Peptide synthesis produces the target peptide along with a mixture of impurities that must be removed before they are used therapeutically. For chemically synthesized peptides, purification requires meticulous methods because these impurities can be structurally similar to the desired product. In this article Gilson covers synthetic peptide purification, focusing on purification by liquid chromatography-mass spectrometry (LC-MS)...

Whilst commonly used air displacement pipettes are highly accurate for most pipetting applications, their performance is adversely affected by the physical properties of the solutions handled, such as viscosity, volatility, surface tension and temperature.  However, positive displacement pipettes like Gilson's ergonomic MICROMAN® E and Capillary Pistons (CPs) work differently, and volume delivery is unaffected by the nature of the sample...

Gilson has launched two new interactive versions of their Fluid News promotional brochures, packed with exclusive special offers, product highlights and resources to make lab life easier for scientists. Each interactive guide contains brand-new offers, including half-price consumables, 4 for 3 on their new personalisable MyPIPETMAN® Select, 40% off their rebranded PIPETMAN® range, and exclusive savings on PIPETMAX®, Gilson's automated liquid handling platform....

The Institute for Research and Innovation in Biomedicine (IRIB) focuses on developing innovative technologies for diagnosing, treating, and preventing diseases. Its research programs are centered around several themes, including cancer, infectious diseases, neurodegenerative diseases, and regenerative medicine. Located in Rouen, France, the IRIB brings together researchers and experts from various fields, including biology, chemistry, physics, and medicine, to collaborate on cutting-edge research projects....

With the introduction of PIPETMAN, we've combined tradition with ease, incorporating all the features and legacy values that made the Classic so popular, but with reduced forces. It maintains the same high standards, reliability, and performance as the Classic, including its design and durability. With less force required, PIPETMAN offers easier handling, enhancing and optimizing your pipetting experience...

Growing demand for analytical laboratory services (and the impact of the COVID-19 pandemic) will see the industry grow globally to about $492 million by 2027. Batch Release Testing shows the biggest growth in the market, estimated to increase at 9% Compound Annual Growth Rate (CAGR). To keep up with the expected demand over the next seven years, you’ll need to know all the latest techniques and analytical methods that could affect your SPE workflows. Here, Gilson discuss some of the latest considerations for your SPE processes...

Oligonucleotides must be of high purity when used within molecular biology applications such as qPCR, next-generation sequencing, and microarray analysis. In the following application note, Gilson explore how the VERITY® Oligo Purification System, configured with automated preparative and analytical HPLC capabilities, can be a solution to isolate, analyze, and desalt reagent-grade oligonucleotides in one continuous run...

For over 60 years, Gilson has prioritized accuracy, precision, and reliability when creating pipettes. Our pipettes are renowned worldwide as a standard in pipetting and have become an iconic tool in laboratories. None more so than the legendary PIPETMAN Classic, which has served as a trusted companion for scientists across the globe for decades. However, as technology advances, our scientific instruments must also evolve. That's why we said goodbye to the iconic PIPETMAN Classic earlier this year and welcomed its successor, the PIPETMAN...

The VERITY 3240 Pump is a welcome addition to Gilson’s VERITY purification portfolio, reaching flow rates up to 150 mL/min and pressures up to 420 bar (6090 psi). This stackable pump saves valuable bench space by holding HPLC system modules on the top. The pump integrates with Gilson’s high-throughput VERITY purification platforms, which are fully and exclusively controlled by TRILUTION® LC Software...

Gilson has recently streamlined its range of PIPETMAN® Classic, PIPETMAN® Neo, and PIPETMAN® G into a single product line called PIPETMAN® to make lab life easier for scientists. The PIPETMAN® range offers a larger range of single and multichannel models giving more flexibility of choice than before. The product line provides accuracy, precision, durability and robustness with the added benefit of reduced pipetting forces...

Gilson has launched two new interactive versions of their Fluid News promotional brochures, packed with exclusive special offers, product highlights and resources to make lab life easier for scientists. Gilson's Biotech Fluid News brochure focuses on lab solutions where quality, safety and compliance are paramount, perfect for Biotech, Pharma and Scientific Research applications. Gilson's Academia Fluid News edition highlights their range of dedicated products aimed at scientists from academia, education, healthcare and life sciences...

Top 5 Questions to fnd the Perfect Preparative HPLC System for your Purification needs. There are many variables to consider when configuring an HPLC system. To help, here are the top five questions you need to answer. Sample Injection, do you need manual or automated sample injection?. Pumping System, what size of column do you need? Detection, what type of detector do you require? Top tips from Gilson...

Gilson has launched a new novel customisable, modular pipette. MyPIPETMAN^® is Gilson’s most comfortable and ergonomic pipette, offering technical and personalisation options to adapt to the researcher’s laboratory needs. The newest MyPIPETMAN mechanical pipettes are available through two main options: MyPIPETMAN Select and MyPIPETMAN Enterprise. As a core life sciences lab tool, pipettes should be lightweight, ergonomic, reliable, and easy-to-use....

Since the start of the pandemic, a surge in sampling demand is putting ?laboratories under pressure, driving up the market, especially in labs that do qPCR and PCR applications. Automated liquid handling platforms, like PIPETMAX®, automate most of the liquid handling steps in your assays, increasing throughput and establishing a robust method for your laboratory workflow. Read our article "The benefits of adding robotics to your lab" to discover the major benefits of adopting automated pipetting systems into your liquid handling workflow...

Gilson, a leader in liquid handling technology, has announced that PIPETMAN® L multichannel pipettes featuring V-rings were awarded a Red Dot Award: Product Design 2022. The PIPETMAN L multichannel pipettes equipped with V-rings were a group of products that stood out among a record number of entries evaluated by an international jury. Since 1993, the Red Dot Award has come to represent high standards of design quality....

Gilson, a leader in purifications systems, announce the launch of the VERITY® 1601 ELS Detector (ELSD). Designed for purifications by semi-preparative and preparative liquid chromatography (LC), the VERITY 1601 ELSD provides a powerful and cost-effective detection method for new compound discovery. The VERITY 1601 ELSD is an evaporative light scattering detector that can detect any analyte with or without a chromophore that is less volatile than the eluent...

Gilson has released the new 2022 Product Guide that contains their latest liquid handling, purification and extraction instruments which help make lab life easier. Gilson, who is a leading global manufacturer of sample management and purification technologies for the life sciences industry, have advanced their guide to be even more interactive and useful.  It has been designed to help signpost customers through to online tools and resources which will help them discover the right solutions for their applications....

Gilson’s AmpliPur® Expert Tips, perfect for molecular biology applications, are in stock, ready-to-ship. Gilson’s AmpliPur Expert Tips are equipped with filters that protect precious samples from cross-contamination and are designed to fit various manual and electronic pipette brands for maximum convenience on the bench. If you would like to try a FREE tip sample in your lab, simply complete the online request form...

Labviva, a leader in life sciences marketplace software that modernizes procurement practices announce Gilson as a strategic supply partner. Gilson’s liquid handling, purification, and extraction solutions will be available through Labviva’s marketplace. Through this partnership, organizations like large pharmaceuticals, research institutions, and biotechnology firms who use the Labviva platform to procure laboratory supplies can easily access Gilson’s portfolio...

Whilst commonly used air displacement pipettes are highly accurate for most pipetting applications, their performance is adversely affected by the physical properties of the solutions handled, such as viscosity, volatility, surface tension and temperature.  However, positive displacement pipettes like Gilson's ergonomic MICROMAN® E and Capillary Pistons (CPs) work differently, and volume delivery is unaffected by the nature of the sample...

Centrifugal Partition Chromatography (CPC) or Counter Current Chromatography (CCC), as it is sometimes known, is a cost-effective solution for natural product purification using liquid-liquid phases rather than a solid stationary phase. With no column to replace or silica to recycle, CPC offers low solvent consumption compared with traditional chromatography techniques and requires no extensive pre-treatment of samples....

Gilson has announced a new UV-VIS detector to its VERITY^® line of purification systems. The VERITY® 1741 UV-VIS Detector is specifically designed with the needs of semi-preparative and preparative HPLC customers in mind. It relies on the power of UV-VIS with diode array detection (DAD) technology, like that found in Gilson's popular PLC Purification Systems. The VERITY 1741 Detector is an ideal solution for purification applications in drug discovery, food supplements, natural products, and biomolecular research.

As the demand for rapid SARS-CoV-2 testing continues to grow, so does the need for accurate, reliable and fast results. Gilson’s new COVID-19 Testing Fluid News Brochure highlights their range of world-renown and trusted manual and automated lab solutions that can easily integrate into your qPCR and RT-Lamp testing workflows. When protection, speed of analysis, reliability and traceability are paramount, Gilson’s range of lab equipment and instruments delivers verifiable data and complete confidence in results...

Whilst commonly used air displacement pipettes are highly accurate for most pipetting applications, their performance is adversely affected by the physical properties of the solutions handled, such as viscosity, volatility, surface tension and temperature. However, positive displacement pipettes like Gilson's ergonomic MICROMAN® E and Capillary Pistons (CPs) work differently, and volume delivery is unaffected by the nature of the sample...

Gilson and Acumium announce their collaboration to develop contemporary technologies and tools for academic and industrial cell culture laboratories. The partnership aims to bring scientists new digital solutions for managing cell culture protocols, data collection and maximizing data use. Both companies see these advances to be of particular importance to pharmaceutical research and the burgeoning cell-based cancer therapeutics arena...

Whilst commonly used air displacement pipettes are highly accurate for applications, viscosity, volatility, surface tension and temperature of samples can adversely affect performance. Positive displacement pipettes like Gilson's ergonomic MICROMAN^® E, along with Capillary Pistons (CPs), offer the highest precision and comfort when pipetting non-aqueous liquids such as oils, cosmetics, blood, glycerol, radioactive samples, RNA, DNA and more...

Lab technicians and clinicians are on the front lines of the fight against the COVID-19 pandemic. With the realities of more infections putting governments, health agencies, and the scientific community under additional pressure, ensuring the safety of skilled resources at all times should be a priority for principal investigators and lab managers...

High performance Liquid Chromatography (HPLC) is the industry standard for cannabinoid extraction, but Centrifugal Partition Chromatography (CPC) offers a cost effective alternative with comparable yields and purity. Below we describe how each method works and what differences to take into consideration during cannabis testing....

With the ever-increasing demand for COVID-19 testing, laboratories are placed under immense pressure for rapid and reliable analysis. Gilson's portable Connected smart devices can create a fully traceable and reliable lab environment from wherever you are, bringing confidence to manual pipetting within your COVID workflow and preserving the integrity of your sample....

The 2021 Gilson Product Guide is now available to download. This year, it’s packed with our liquid handling, extraction and purification instruments, enabling verifiable science and making lab life easier for researchers. With the current pandemic, this new guide also features solutions dedicated to COVID-19 research. We’ve consolidated our tools, technology, services, and resources to help scientists as they ramp up testing capabilities or study the virus...

Grab 25% of more off Gilson’s world-renown pipettes.  Choose from their ergonomic, manual or electric, single and multichannel models.  Hurry, limited time offer. Gilson is world-renowned for our accurate, comfortable, and reliable PIPETMAN^® pipettes. Available in a variety of ergonomic designs, volume sizes, and channels, our pipettes can enhance your pipetting experience and help you achieve reproducible results...

Gilson has developed a compact, low-cost tube filling system that has the flexibility to fill bottles, tubes, vials, or microplates quickly. With the current pandemic, there is an exponential demand for diagnostic testing of patients for COVID-19, the disease caused by the SARS-CoV-2 virus.  Viral transport media (VTM) is a critical component of COVID-19 test kits and is used for the collection, transport, and storage of clinical specimens....

Gilson has released two new models to the PIPETMAN® L range of pipettes, the most comfortable air-displacement pipettes in the Gilson portfolio. The PIPETMAN L x1200 multichannel pipettes are available in 8- and 12-channel models, helping scientists increase their daily productivity without sacrificing comfort. These new 1200 µL multichannel models are an ideal solution for many protocols that require a working volume from 100 to 1200 μL....

Testing for coronavirus is an essential diagnostic and research tool for monitoring and managing the current pandemic. qPCR and RT-qPCR are proving to be powerful techniques for testing labs worldwide for the detection of SARS-CoV-2. However, each step in the extremely sensitive qPCR procedure can potentially contribute to experimental error and affect the reproducibility of results...

Gilson has consolidated tools, technology, services and resources to help scientists ramp up testing capabilities or study the SARS-COV-2 virus. Their new PCR FOCUS Fluid News Brochure highlights their world-renown manual and automated sample prep technologies suitable for COVID-19 diagnostics and research. For such situations when protection, speed of analysis, reliability and traceability are paramount, Gilsons range of lab equipment and instruments can deliver verifiable data and confidence in results.

For decades, Gilson and our legendary PIPETMAN® instruments have been synonymous with pipetting. We believe nobody knows more about liquid handling than we do and, certainly, nobody cares more about our pipettes than us. Regular pipette maintenance, calibration and servicing are essential to ensure reliable performance and verifiable results. By using our Gilson accredited Pipette Service Centres, you can entrust us to service, calibrate and repair your Gilson pipette...

Gilson, renown experts in liquid handling, are hosting a series of seminars across Europe on “How to Enhance your Manual and Automated Liquid Handling”. Liquid handling is at the heart of most laboratory practices. From manual pipetting, transferring simple solutions, through to complex extractions and purifications, they all present unique challenges that can affect the reproducibility, accuracy and productivity of experiments....

An ideal choice for SPE clean-up prior to LC-MS for bioanalysis, the ASPEC Manifold incorporates easily into laboratory workflows and provides a fast and simple way to prepare several samples for later analysis. It offers a cost-effective approach to automation for clinical, forensic, and food or beverage testing laboratories....

Gilson, renowned for their legendary PIPETMAN pipettes have enhanced their range by adding new features and updates to their PIPETMAN® Classic and PIPETMAN® G models. Trusted by scientists worldwide as one of the pipetting standards for robustness and performance, this new update reinforces the PIPETMAN Classic as the benchmark in pipetting excellence....

Mass spectrometry (MS) technology has become an essential tool in the purification field. Once viewed as a complex and expensive process requiring highly specialized technicians to operate, the VERITY 1910 MS Detector makes MS detection simple and affordable for any preparative purification system. The VERITY® 1910 MS Detector is a unique, chip-based mass detector that can be integrated....

Gilson has launched a brand new range of benchtop instruments that perfectly complements their pipetting systems and laboratory workflows. The new benchtop instruments feature a variety of advanced technologies for mixing, temperature control, and centrifugation that improve lab productivity and save valuable time. For a limited time, Gilson are offering an introductory 15% discount across the Benchtop range....

Positive displacement pipettes have been used for many years for PCR applications. Gilson, experts in liquid handling have published three new papers which describe the use of positive displacement technology to help solve the issues of pipetting problem liquids.

Gilson’s MICROMAN E positive displacement pipette with its Capillary Pistons helps scientists counter common pipetting problems that may affect accuracy and precision when working with problem liquids. Leaks are known to occur when pipetting volatile solutions such as acetone, hexane and ethanol with an air-displacement pipette.

With the capability to purify compounds by preparative HPLC and FLASH on the same instrument, Gilson's Personal Liquid Chromatography (PLC) systems will simplify and streamline compound purification for your lab - accelerating your research.

These customizable instruments are available in a simple configuration for basic applications, but with a wide range of upgrade options in order to meet the demands of more advanced organic/medicinal chemists and experienced chromatographers. Systems are controlled via an intuitive touch screen interface, making it easy to write and edit methods, or adjust parameters on the fly....

Gilson have released two new brochures for PCR and ELISA applications, highlighting the latest technology and products that help researchers enhance throughput.

Gilson’s PCR brochure introduces the new qPCR pipetmaX, a simple and complete solution for reproducible qPCR sample preparation workflows for 10’s and 100’s of samples.  Their range of pipettes, Starter Kits and manual 96 channel pipetting systems help streamline PCR protocols for accurate, dependable results. Download the PCR brochure for the latest product information and special offers, including 25% off PlateMaster....

Gilson, the global leaders in liquid handling and purification are proud to announce distributorship of a selection of tubes and plates frequently used in lifescience analysis routines into the UK market.

The new plasticware range includes microtubes, microplates and reservoirs that are regularly used in-house and recommended for use on both the PipetmaX® and Flexus liquid handling platforms.  Combining the most popular lines from Simport, Heathrow Scientific and Porvair, these strong-pedigree products are offered by Gilson UK to provide a single reliable source of the most respected laboratory vessels available for both manual pipetting or integration with automated liquid handling systems....

The Nanodrop nanolitre dispensing instrument line is a robust laboratory automation and liquid handling solution to life science researchers worldwide. 

Produced by Bionex Inc and distributed in the UK through Gilson these low-volume automated pipetting systems offer the highest level of performance in the industry. The Nanodrop allows miniaturization of samples and is the ideal tool for those using 384 and 1536 well plates. Typical applications include MALDI plate spotting, cell/bead dispensing, protein crystallography and high throughput screening....

The well respected GE Osmonics transfer membrane and general lab filtration range is now supplied by Maine Manufacturing Inc and distributed in the UK by Gilson UK.

Routinely used in DNA/RNA and protein blotting applications these membranes combine high material purity and strong binding affinity with excellent dimensional stability. Nitrocellulose, nylon and PVDF membrane types are all high binding/low background engineered. Pure nitrocellulose is ideal for single transfers while nylon has a higher binding capacity (approx 350µg-cm²) and binds a greater range of fragment sizes....

The pipette of choice for problem liquids

The Gilson MACROMAN is a large volume motorised pipette controller designed for dilutions, sampling, media preparation and more. It can be used with graduated pipettes up to 100ml in volume providing a safer, more efficient and consistent method of dosing than manual systems allow....

The Innovadyne Nanodrop II and Nanodrop Express liquid handlers from IDEX are market leaders in low volume, non-contact sample handling. These instruments can aspirate and dispense both samples and reagents across a wide range of biological applications. The Nanodrop has a wide dynamic volume range from 50nl to 500µl allowing procedures to utilize both large and small volumes without compromising accuracy or precision...