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  New Versatile Microplate Sealing System

AutocapperPorvair Sciences announce Autocapper – a new affordable microplate sealing system designed to work with reusable mat caps (friction seals) from all the major manufacturers. Set-up to quickly and securely seal 96-well deep well microplates as standard, the Autocapper is compatible with shallow well and several other plate formats (24-well, 48-well) using a range of supplied adapter blocks. Designed to meet the needs of laboratories for low to medium throughput microplate sealing, the Autocapper is compact and easy-to-use....

 

  Porvair Introduce Reservoir Troughs for Multi-Channel Pipetting

new 8- and 12-channel reservoir troughsPorvair Sciences has introduced new 8- and 12-channel reservoir troughs to help improve multichannel pipetting convenience and productivity in high-throughput laboratories. The reservoir troughs are designed to hold liquid reagents in precise rows that align with 8-channel and 12-channel pipettes allowing researchers to simultaneously aspirate or dispense fluids in all channels.  These reservoir troughs help laboratories improve productivity by increasing the speed and...

 

  Advanced Porous Plastics for Medical & Life Science Applications

Porvair's BioVyonPorvair Sciences, original manufacturers of porous plastics, will be showcasing its advanced materials for the medical and life science markets at this year’s COMPAMED exhibition in Dusseldorf, Germany. Visitors to Booth F08 in COMPAMED Hall 8a, will be able to learn how Porvair's BioVyon™ range of high-performance porous materials have been incorporated into products to achieve more sensitive analysis, better healthcare, improved medical...

 

  Automated Solvent Removal from Tubes & Microplates

ultravap mistralPorvair Sciences new UltraVap Mistral XT 100 allows for the first time, full automated dry down of organic solvent-based samples in tubes up to 100mm in length. The UltraVap Mistral XT 100 is Porvair Sciences latest fully robot compatible nitrogen blow-down evaporator, suitable for integration adjacent to most leading laboratory liquid handling robots. Designed with the demands of linear robots very much in mind, the UltraVap Mistral XT 100...

 

  Public Launch of Porvair Lab Division

Porvair SciencesPorvair has chosen Lab Innovations 2018 to bring together, for the first time on a single exhibition stand (G16), all the latest products and application solutions from its fast-growing Laboratory Division. The Laboratory Division designs and manufactures instruments and consumables for use in environmental and bioscience laboratories with a particular focus on water analysis instruments and sample preparation...

 

  Think Finneran Pink

Beginning October 1st through December 31st, a portion of each sale of our Pink promotional products will be donated to Gilda’s Club. Our donation will be made in the memory of our company founder and Mom – Josephine Finneran. Gilda’s Club is a community organization for people living with cancer, their families and friends....

 

  Fast LC/MS Sample Preparation Microplate

P3 microplatePorvair Sciences reports how its P3 microplate can be used to accelerate removal of interfering proteins from serum, plasma or even whole blood samples prior to analysis by Liquid Chromatography / Mass Spectrometry (LC/MS). Biological samples commonly contain proteins that interfere with downstream applications. Traditionally scientists have used the CRASH method....

 

  Compact Electronic Pipette Filler Perfect for Fumehood Use

UltraJet electronic pipette fillerCompact in size, the UltraJet electronic pipette filler from Porvair Sciences is perfect for use even in confined spaces such as safety cabinets and fume hoods. The UltraJet pipette filler is quick and simple to operate. Its lightweight, ergonomic design ensures you can use it for extended periods of time without discomfort.....

 

  Automation Friendly Cell Growth Microplates

BactiGrowth rangePorvair Sciences has extended its BactiGrowth range of specially packaged plates designed to enable high yield growth of bacteria, yeast, mammalian or insect cell lines. Precisely manufactured to conform to the automation-friendly ANSI/SBS format, BactiGrowth plates are available in plate formats from 24- through to 384-well and well volumes from 300 µl to 10 ml per well to....

 

  High Strength Headspace Vials

high strength rounded or flat-bottomed headspace vialsPorvair Sciences announces its JG Finneran range of high strength rounded or flat-bottomed headspace vials which are available in 6mL, 10mL, 20mL, and 27mL capacities. Available in either clear glass, or amber glass for light sensitive samples, each vial's wide opening allows samples to be simply and quickly added....

 

  New DNA Kits Catalogue

Porvair DNA KitsPorvair Sciences has produced an informative catalogue that describes its growing range of easy-to-use kits for DNA extraction, purification and size selection. Obtaining DNA from biological samples is the first and most crucial step in molecular biology. Eluting both high quality and high yield of DNA from a wide range of biological samples can be challenging...

 

  Stackable Rack for 12mm Vials and Tubes

JG Finneran 50-position stackable rackPorvair Sciences has introduced the JG Finneran 50-position stackable rack for 12mm vials and tubes. This new stackable rack is designed to hold 12mm vials and tubes in the optimum orientation for pipetting tasks. Available in blue, black and white as standard, the 50-position rack is securely stackable saving valuable bench space....

 

  Wide Range of Reagent Reservoirs

reagent reservoirsAvailable in 96- and 384-well configurations - Porvair Sciences reagent reservoirs are designed for simple integration into any automated liquid handling system. Reagent reservoirs provide an economical way to divide up reagents and wash stations on the deck of automated liquid handling systems. Made to the ANSI/SLAS standard, Porvair reagent reservoirs can be used with most liquid handlers and are fully...

 

  Cell Based Screening Array Enhances Drug Discovery

Cell Based Screening ArrayPorvair Sciences has collaborated with Persomics Inc. to develop and supply ANSI/SLAS format Arrays as an OEM product for their ImagineArray™ platform. On the Persomics ImagineArray™ platform, traditional microplate wells are replaced with contact-printed spots on a slide which is mounted into an SLAS/ANSI format frame. Each spot is a...

 

  Circular Dichroism Measurement in Microplates

black Krystal UV Quartz bottomed microplatesPorvair Sciences introduces new black Krystal UV Quartz bottomed microplates that offer excellent optical transmission in the wavelength range 185nm to 1100nm making them ideal for labs looking to make Circular Dichroism (CD) measurements....

 

  Versatile 96-well Multi-Tier Microplate System for High Throughput Chromatography

patented 96-well Multi-Tier Microplate SystemThe patented 96-well Multi-Tier Microplate System (MTP) from Porvair Sciences and sister company - JG Finneran is a unique device providing analysts with the convenience of an ANSI/SLAS microplate footprint but loaded with inert glass vials. Minimising the risk of extractables leaching out into samples to be analysed, the MTP accommodates a wide range of vial volumes enabling it to be...

 

  New Stackable Vial Rack for 12x32mm Vials from J.G. Finneran

J.G. Finneran the industry leader in quality chromatography vials and accessories introduces the new Stackable Vial Rack for 12x32mm vials. Unique chromatography sample vials, closures and accessories manufactured by J.G. Finneran Associates are available internationally from a network of laboratory dealers. J. G. Finneran along with Porvair Sciences will be exhibiting at analytica 2018 – Hall A.1 Stand 523. Please come by and visit us to see what the Finneran Porvair team has to offer....

 

  Guide to Microplate Closure & Sealing

Guide to MicroplatePorvair Sciences, in conjunction with sister company – JG Finneran Associates Inc., has produced a new informative guide to assist lab scientists select the optimum seal and closure device for different types of microplate. Choosing the correct combination of seal and closure device for each type of microplate is important to achieving best laboratory practice and to avoid unnecessary work further downstream. Microplates are a convenient method...

 

  Streamlining ChIP-Seq Library Preparation

Porvair Sciences announces the launch of UniqSeq - a new ChIP-Seq library preparation kit. High quality library preparation is key to a successful ChIP-Seq experiment. Obtaining complex libraries with good coverage and low bias are just some of the features that depend on high quality DNA after performing ChIP assays. As a new or occasional user, creating these libraries can seem like a daunting task.....

 

  Speciality Microplate Design & Manufacture

Porvair Sciences is a leader in bespoke and speciality microplate design and manufacture. Closely examining the needs of clients for special microplate designs, assembly techniques and plate structure, Porvair can deploy more than 30 years’ experience in the design, assembly and testing of microplates to deliver a world-class final product that can meet or exceed the most exacting specifications....

 

  High Performance ChIP-Seq kit for Fresh & Frozen Tissue Samples

Porvair Sciences announces a new and improved Chromatrap® ChIP-Seq kit (v.1.5) that is optimised to work from fresh and frozen extracted tissue as well as cell lines. This latest version of the popular Chromatrap® ChIP-Seq kit enables ChIP to be performed from as little as 50mg of a wide range of extracted tissue samples. The new protocol incorporates optimised lysis and hypotonic buffers and guidelines on how to achieve maximum...

 

  Impact Support Mats Protect Microplates During Centrifugation

Porvair Sciences silicone impact support matsPorvair Sciences has extended its range of silicone impact support mats to protect deep well microplates when they are being centrifuged. Designed to fit into the skirt of the deep well plates, silicone impact support mats allow plates to be used in a centrifuge without risking plate distortion, cracking or breaking, resulting in well leakage and loss of valuable samples. Impact support mats are now available for Porvair Sciences square deep well plates (2ml, 1ml and 350ul), round well plates (2ml & 1ml) and range of large volume deep well plates....

 

  Microplate & Chromatography Products at Analytica 2018

microplatePorvair Sciences has announced that it will showcase its latest microplate and chromatography products at the forthcoming Analytica 2018 exhibition in Munich, Germany. Designed for high recovery extraction of analytes from biological fluids, the 96-well Supported Liquid Extraction (SLE) microplate operates without the need for offline steps such as protein precipitation. The large pore size and high pore volume of...

 

  Porvair Sciences to Feature on Sky TV

Porvair Sciences LtdPorvair Sciences Ltd, a leading supplier of separation and filtration technology for life science and healthcare applications, is hitting the small screen in a special showcase of its healthcare expertise.

Porvair was chosen to be part of a documentary that’s set to be broadcast on Sunday 7 January 2018 at 10am. Entitled ‘Products to Benefit Healthcare’ the programme was filmed in August 2017 at Porvair Sciences facility in Wrexham, North Wales, and will be shown on Sky Digital channel 189....

 

  UK / Chinese Collaboration to Develop Innovative Technologies for Epigenetic Analysis

chromatin immunoprecipitation platform.Porvair Sciences are teaming up with Suzhou Tianlong Bio Technology Co Ltd (China), together with Swansea University and Xi'an Jiaotong University in a collaborative project

The project will integrate Porvair's innovative solid-state chromatin immunoprecipitation platform, ChromatrapŽ with Tianlong's expertise in automated robotic technologies and diagnostic multiplex PCR kits to develop innovative technologies in epigenetic characterisation for patient stratification in renowned precision medicine.

 

  Solvent Dry-Down for LC/MS Sample Preparation

Porvair Sciences complete range of MiniVapPorvair Sciences has posted a new online video demonstrating how nitrogen blowdown evaporators offer a useful tool for removing the solvent dry-down bottleneck in LC/MS sample preparation.

In the new video the presenter demonstrates how nitrogen blowdown evaporators can quickly and easily remove most chromatographic solvents, enabling fast recovery of dry compounds and allowing re-suspension of unknown mixtures in optimised solvents for LC/MS analysis. Additionally, the video introduces Porvair Sciences complete range of MiniVap and UltraVap blowdown evaporators. Blowdown evaporators give significant throughput advantages...

 

  Easy-to-Use, Easy-to-Choose DNA Purification Kits

Chromatrap, a leading developer of cutting-edge life science products, has launched an affordable, easy-to-use range of DNA kits for routine molecular biology applications. 

easy-to-use range of DNA kitsLeveraging proprietary buffer chemistry and unique spin column design, ChromatrapÂŽ DNA kits are all free from salts, contaminants and inhibitors, providing you with the high recovery of top quality DNA perfect for downstream applications....

 

  Biological Sample Preparation Using a Protein Precipitation Plate

Porvair Sciences has published an informative video demonstrating how to use a solid-state filter microplate to remove interfering proteins from serum, plasma or even whole blood samples prior to analysis by LC/MS

Biological samples commonly contain proteins that interfere with downstream applications. The Porvair Sciences Protein Precipitation Plate (P3) plate uses the CRASH method, in which the protein is denatured with acetronitrile and the flocculant filtered out, allowing 96 samples to be handled at one time....

 

  Chemically Resistant Pierceable Microplate Cap Mats

Porvair Sciences has introduced a new range of pierceable cap mats from sister company, JG Finneran Associates Inc.

Pierceable Microplate Cap MatsThese new cap mats ensure the integrity of samples in Porvair 96-well Deep well microplate with glass inserts used in high throughput chromatography. Manufactured from chemically resistant PTFE with a silicone lining, the new JG Finneran pierceable cap mats come with a specially weakened area....

 

  Speciality Microplate for Microbial Research

Porvair Sciences reports on the revolutionary “FlowerPlate” microplate developed and manufactured as an OEM product with and for m2p-labs in Germany.

FlowerPlate microplateBased in Baesweiler, Germany, m2p-labs was founded in 2005 as a spin-off of RWTH Aachen University. The company focuses on development and supply of systems for microreaction and automated solutions for screening and bioprocess development.....

 

  High Performance ChIP Assays from Nanograms of Starting Material

Chromatrap has demonstrated that its unique solid state patented technology allows for ChIP-seq assays to be routinely performed from as little as 500ng of chromatin.

Chromatrap ChIP-SeqTraditionally availability of starting material has been a major problem for epigenetics researchers. The available techniques for tackling small samples which provide low yields of chromatin are usually long and complex, and involve pooling or the spiking of samples with chromatin from another source....

 

  High Recovery Extraction of Analytes from Biological Fluids

The 96-well Supported Liquid Extraction (SLE) microplate from Porvair Sciences is designed for routine, high recovery extraction of analytes from biological fluids.  

microplate from Porvair SciencesHigh analyte recovery, free of proteins and phospholipids, is routinely obtainable without the need for offline steps such as protein precipitation using this new plate. The large pore size and high pore volume of the diatomaceous earth inert support in the SLE microplate, combined with a wide working range....

 

  Krystal Microplate Enables Development of Drug Testing Assay

Porvair Sciences reports that the National Center for Biological Sciences (NCBS) in Bangalore, India is using its Krystal 384 black microplate to produce a standard drug testing assay for Plasmodium vivax infection.

Krystal 384 black microplateThe NCBS is a leading national institute whose faculty members undertake research in the frontier areas of biology. Scientists at the NCBS use experimental and computational approaches to study molecules, cells and organisms creating an understanding of the biology at each of these levels to advance an integrated view of life processes....

 

  Krystal Microplate Enables Development of Drug Testing Assay for Plasmodium vivax

Porvair Sciences reports that the National Center for Biological Sciences (NCBS) in Bangalore, India is using its Krystal 384 black microplate to produce a standard drug testing assay for Plasmodium vivax infection.

Krystal Microplate The NCBS is a leading national institute whose faculty members undertake research in the frontier areas of biology. Scientists at the NCBS use experimental and computational approaches to study molecules, cells and organisms creating an understanding of the biology at each of these levels to advance an integrated view of life processes....

 

  Deep-Well Plate Selection Guide

Porvair Sciences announces the availability of a new guide that improves your background knowledge and makes selection of the optimum deep-well microplate for your application both quick and easy.

deep well platesDeep-well plates are used in a wide variety of applications including compound storage, fraction collection, sample mixing and preparation. Choosing the correct deep-well plate for your application can mean the difference between indifferent and great results. The easy-to-use guide provides....

 

  Supported Liquid Extraction Microplate for Biological Fluids

Porvair Sciences announces a new easy-to-use 96-well Supported Liquid Extraction (SLE) microplate designed for high recovery extraction of analytes from biological fluids.   

easy-to-use 96-well Supported Liquid ExtractionUsing the Porvair SLE plate high analyte recovery, free of proteins and phospholipids, is routinely obtainable without the need for offline steps such as protein precipitation. Supported Liquid Extraction is a separation technique similar to traditional liquid-liquid extraction....

 

  Chromatrap Announce Native ChIP Kit for Mass Spectrometry

Chromatrap announces that its popular Native ChIP kit is now fully compatible for mass spectrometry (MS) as a downstream process.

ChIP Kit for Mass SpectrometryCombining Chromatrap®’s unique solid-state ChIP technology with MS enables researchers to obtain high quality data sets for chromatin proteomic profiling and mapping of histone modification patterns....

 

  Major Biomedical Research Reagents Supplier Licences Chromatrap ChIP Technology

ChromatrapŽ announces that BioLegend, a major US-based manufacturer and supplier of reagents and kits for biomedical research, has chosen their novel solid-state ChIP technology to power a new range of faster and more efficient chromatin immunoprecipitation kits. 

new kits will combine BioLegend expertiseThese new kits will combine BioLegend's expertise in developing the Go-ChIP-Grade™ antibodies that are validated for ChIP assays with the patented solid-state immunocapture surface at the heart of every Chromatrap® product....

 

  Deep-well Plate Removes Risk of False Peaks in uHPLC & MS Applications

Porvair Sciences new Glass Vial Deep-well plate is designed to ensure that absolutely no extractables or leachates are present in a withdrawn sample, thereby removing the risk of false peaks in sensitive uHPLC and MS applications.

Deep-well Plate Removes Risk of False PeaksThis high-quality product combines 96 x 1ml tapered or flat bottomed glass vials held firmly in each well of a 2ml 96 Deep-well plate.  Porvair Glass Vial Deep-well plates are less costly than solid glass plates and are precisely manufactured to comply with ANSI/SLAS dimensions to ensure complete compatibility with automated equipment....

 

  Extractables-free Deep-well Plate for uHPLC and MS Applications

The new Glass Vial Deep-well plate from Porvair Sciences is designed to ensure that absolutely no extractables or leachates are present in a withdrawn sample, thereby removing the risk of false peaks in sensitive uHPLC and MS applications.

Extractables-free Deep-well Plate for uHPLCThis high-quality product combines 96 x 1ml tapered or flat bottomed glass vials held firmly in each well of a 2ml 96 Deep-well plate.  Porvair Glass Vial Deep-well plates are less costly than solid glass plates and are precisely manufactured to comply with ANSI/SLAS dimensions....

 

  Unique Drip Geometry Improves Sample Recovery from Filtration Plates

Porvair Sciences announces a new range of 384-well filtration plates with a unique drip geometry which provides unmatched sample recovery.

384-well filtration platesBy cleverly re-shaping the drip director, and giving it a compound curve structure, the new filtration plates virtually eliminate the traditional “hanging filtrate” effect where excess filtrate clings by surface tension to the outside of the structure. In addition to improving total sample recovery, the new filtration plate design helps to minimise work surface and sample contamination as well as improving productivity...

 

  FFPE ChIP-seq Assay Kit for Tissues, Biopsies and Difficult to Lyse Samples

Chromatrap® has introduced a new and improved version of it’s popular solid phase chromatin immunoprecipitation (ChIP) assay kit for chromatin extracted from Formalin Fixed Paraffin Embedded (FFPE) tissue.

Chromatrap FFPE ChIP-seq kit protocol Ideal for tissue samples, biopsies and difficult to lyse samples, the ChromatrapÂŽ FFPE ChIP-seq kit has overcome the issues often associated with FFPE ChIP, by offering a streamlined protocol which provides the user with excellent quality isolated chromatin....

 

  Comparative Study of Native & Crosslinked Immunoprecipitation

ChromatrapÂŽ has published a new article that describes a detailed genome wide comparison of native and crosslinked chromatin immunoprecipitation followed by next generation sequencing (ChIP-seq) using the company's patented solid state spin column technology.

Native & Crosslinked Immunoprecipitation ChromatrapÂŽ supply high quality N-ChIP-seq and X-ChIP-seq kits. This article compares the enrichment of the histone H3K4me3 modification signal across the whole genome, from chromatin prepared by both methods (native vs cross link)....

 

  Porvair Acquires J.G. Finneran Associates Inc.

Porvair Sciences is pleased to welcome J. G. Finneran Associates into the Porvair family following its acquisition by Porvair plc. 

porvairJ.G. Finneran designs, manufactures and distributes specialist laboratory consumables including vials, filters, microplates, closures and ancillary products. Finneran products clearly complement the biotechnology and chromatography product lines of Porvair Sciences and the combined product ranges will provide an enhanced offering to all customers....

 

  Comparing Sensitivity & Efficiency of N-ChIP-seq and X-ChIP-seq Kits

ChromatrapÂŽ has published a new article that describes a detailed genome wide comparison of native and crosslinked chromatin immunoprecipitation followed by next generation sequencing (ChIP-seq) using the company's patented solid state spin column technology.

 N-ChIP-seq and X-ChIP-seq kitChromatrapÂŽ supply high quality N-ChIP-seq and X-ChIP-seq kits. This article compares the enrichment of the histone H3K4me3 modification signal across the whole genome, from chromatin prepared by both methods (native vs cross link). The histone mark H3K4me3 was chosen for this study to highlight the sensitivity and efficiency of the Chromatrap...

 

  Versatile Automation Friendly Dry Down Station

Porvair Sciences has introduced a new version of its popular Ultravap Mistral automatic dry down station - the Mistral Ex.

ultravapWith an adapted sample platform the automation-friendly Mistral Ex is able to productively remove solvent from a wide range of sample formats including 24 to 384-well format deep and shallow well plates, vials and now test tubes up to 100mm high. The Mistral Ex uses warm nitrogen gas blown down into the microplate wells, vials or tubes, just above the liquid level....

 

  Genomics Community Welcomes ‘Seed Busting’ Microplate

Porvair Sciences launched their new Seed Genomics microplate at the recent Plant & Animal Genomics 2017 conference in San Diego (USA) and received an enthusiastic response from the assembled scientists. 

Seed Genomics microplateVisiting genomic researchers were particularly impressed by the strong reinforced polypropylene deep well plate with its matching polypropylene cap mats. The extra ribbing underneath the plate to support its use in a GenoGrinderÂŽ bead beater system* was a feature welcomed by many visitors who saw the plate....

 

  Undertaking ChIP Assays Using Low Cell Numbers

ChromatrapÂŽ has published a new application note that demonstrates how its unique solid state patented technology provides unrivalled sensitivity allowing users to perform ChIP assays using as few as 1000 cells per immunoprecipitation.

performing ChIPUsually large cell numbers are required for performing ChIP, which poses something of a challenge when dealing with limited starting material. The available techniques for tackling small amounts of sample, rare cell types or difficult cell types which provide low yield of chromatin are usually long and complex, and involve DNA amplification or the spiking of samples with chromatin from another source. In the application note, the authors demonstrate how...

 

  96-well DNA Purification Plates

ChromatrapŽ reports on the excellent results achieved by customers using their 96 well high throughput plates for ultra-pure DNA purification. 

96-well DNA Purification PlatesUsing proprietary filtration media that offer much higher loadings of active material, assay times of less than 5 minutes are routinely achievable. Customers report that using ChromatrapÂŽ DNA purification kit that DNA samples ranging from 50 bp up to 23 kb can be purified with up to 98% recovery.....

 

  Low Cell ChIP – a Process Capable of Using as Little as 1000 Cells

ChromatrapÂŽ has published a new application note that demonstrates how its unique solid state patented technology provides unrivalled sensitivity allowing users to perform ChIP assays using as few as 1000 cells per immunoprecipitation.

porvair scientistUsually large cell numbers are required for performing ChIP, which poses something of a challenge when dealing with limited starting material. The available techniques for tackling small amounts of sample, rare cell types or difficult cell types which provide low yield of chromatin are usually long and complex, and involve DNA amplification or the spiking of samples...

 

  Versatile Laboratory Sample Sealer

Porvair Sciences announces the introduction of Autocapper - a versatile electronic applicator that enables friction sample seals to be quickly and securely applied to both microplates and microtube racks.

AutocapperThe simplicity of the Autocapper design, which features a drawer to hold your microplate and cap mat, ensures highly reliable, high integrity sample sealing over many years’ service. Incorporating a powerful motor the Autocapper is able to apply sufficient force to fit cap mats of varying materials to most commercial available deep well plates....

 

  Porvair Launch Versatile Laboratory Sample Sealer

Porvair Sciences announces the introduction of Autocapper - a versatile electronic applicator that enables friction sample seals to be quickly and securely applied to both microplates and microtube racks.

AutocapperThe simplicity of the Autocapper design, which features a drawer to hold your microplate and cap mat, ensures highly reliable, high integrity sample sealing over many years’ service. Incorporating a powerful motor the Autocapper is able to apply sufficient force to fit cap mats of varying materials to most commercial available deep well plates....

 

  Are You Struggling with Chromatin in your ChIP Assays?

ChromatrapŽ  offers an optimised unique buffer chemistry that provides the leading solution for the isolation of high quality and high yield chromatin.

human regulatory chromatinThe success of any ChIP assay is dependent upon the quality of your chromatin. The unique buffer system for chromatin extraction developed by ChromatrapŽ has been cited in a growing number of recent publications investigations into G-quadruplex structures in human regulatory chromatin and receptor signals in natural killer cells....

 

  Porvair Showcases Products for Plant & Animal Genomics

Porvair Sciences will showcase two important technical breakthroughs at PAG XXV in San Diego (USA) from January 14-18, 2017.

brand-new 96-well Seed Genomics plate setsTheir brand-new 96-well Seed Genomics plate sets a new standard for high throughput plant genomics sample preparation. Unlike most commercially available deep well plates, the Seed Genomics plate has been proven to withstand demanding applications using steel ball bearings in the wells shaken at up to 1500rpm used to homogenise seeds, leaves or tissue ready for DNA extraction...

 

  Re-usable Capmats Offer Increased Chemical Resistance

Porvair Sciences announces a new range of 96-well (square and round) capmats made from 100% pure silicone that has been conditioned for low bleed and ease of needle penetration when used with autosamplers.

96-well (square and round) capmatsAdvantageously these silicone capmats reseal after each piercing and may be re-pierced many times without loss of function. Specially treated with a PTFE coating, Porvair silicone capmats offer increased chemical resistance thereby maintaining high sample integrity even over extended periods of time. Resistant to organic solvents including ethanol, methanol, DMSO and DMF, these flexible silicone capmats individually seal the top of each microplate well reducing the chance of...

 

  Preparing High Quality Fragmented Chromatin for ChIP Analysis

The ChromatrapÂŽ Enzymatic Shearing Kit provides an excellent method for the preparation of high quality, ideally fragmented chromatin for ChIP analysis.

The ChromatrapÂŽ Enzymatic Shearing Kit The success of a ChIP assay is highly dependent on the quality of chromatin prepared. The Enzymatic shearing kit provides buffers to optimise the shearing conditions of your chromatin by enzymatic digestion. Chromatin prepared using this kit demonstrates excellent enrichment, independent of starting cell number...

 

  Chromatin Immunoprecipitation (ChIP) Applications Compendium

ChromatrapŽ has published a comprehensive Applications Compendium that includes hints and tips to improve your Chromatin Immunoprecipitation (ChIP) experiments, increase the effectiveness of your ChIP-seq library preparation and brings together its latest application notes in one informative document.

comprehensive Applications CompendiumChromatrapŽ solid-state ChIP technology has been adopted and shown by leading research groups worldwide to be more efficient than conventional bead-based methodologies. This is because the solid phase porous polymer, functionalized with either protein A or G, provides a greater surface area for chromatin antibody binding with very low non-specific binding....

 

  Informative ChIP Applications Compendium

ChromatrapŽ has published a comprehensive Applications Compendium that includes hints and tips to improve your Chromatin Immunoprecipitation (ChIP) experiments, increase the effectiveness of your ChIP-seq library preparation and brings together its latest application notes in one informative document.

Applications CompendiumChromatrapŽ solid-state ChIP technology has been adopted and shown by leading research groups worldwide to be more efficient than conventional bead-based methodologies. This is because the solid phase porous polymer, functionalized with either protein A or G, provides a greater surface area for chromatin antibody binding with very low non-specific binding.....

 

  Porvair Announce Record Sales of Microplate Evaporators

Porvair Sciences has confirmed that 2016 will see record sales of its Ultravap and Minivap ranges of blowdown evaporators to laboratories worldwide. 

minivapThe company first began selling nitrogen blowdown evaporators for microplate sample drying in 1999. Offering unmatched ease of integration into robotic liquid handling workflows, the latest Porvair microprocessor controlled evaporators, the Ultravap Mistral and Ultravap Levante, has consolidated their position as a leading international supplier of microplate evaporators....

 

  Validated Antibodies for Mammalian Epigenetic Research

ChromatrapÂŽ announces that seven further popular antibodies have been validated for use in chromatin immunoprecipitation (ChIP) assays by their UK-based research team.

chromatrapThe new crop of antibodies represents some of the most frequently-cited antibodies in mammalian epigenetic research including H3K4me1, H4K5ac, H4K12ac, H2Az, H3, H4, H3K9me1 and H3K9me2. In addition the new ChIP validated antibodies are now available from ChromatrapÂŽ with matching primers....

 

  ChIP-seq Assay Kit for Histone Methylation

ChromatrapÂŽ reports on the advantages of using its Chromatin Immunoprecipitation Sequencing (ChIP-seq) assay kits for histone methylation applications.

Chromatin Immunoprecipitation SequencingChromatrap’s® ChIP-seq kit uses solid state technology in parallel with high throughput sequencing to deliver a streamlined ChIP-seq protocol from small cell numbers and low chromatin concentrations to investigate the epigenetic landscape. Specifically adapted for broader chromatin concentrations, Chromatrap® ChIP-seq combines the dynamic range of Chromatrap® with the downstream analysis power of deep sequencing...

 

  High Productivity SPE Sample Preparation

Proven in labs around the world, the Porvair Sciences Microlute SPE sample preparation system provides a fast, trouble-free alternative to cartridges for high productivity sample clean-up.

Microlute SPE sample preparation systemThe Microlute SPE sample preparation system also enables you to increase your assay sensitivity by providing reliable pre-injection clean-up and concentration on samples as small as 150¾l. Supplied as a package including filter plate, collection plate, waste tray and manifold, the Microlute SPE sample preparation system contains all the elements to deliver the advantages of high productivity SPE sample preparation in a convenient microplate format. Microlute SPE plates are available...

 

  Wide Range of Epigenetic Assay Kits for Genomic Research

Chromatrap is a pioneer in the development of solid-state filter-based technology that significantly enhances and accelerates the important epigenetic research tool of chromatin immunoprecipitation (ChIP). 

Chromatrap 24 column ChIP-qPCRThe company has developed a range of optimised ChIP assay kits for use in many areas of genome research including classical qPCR, DNA sequencing and from formaldehyde fixed paraffin embedded samples (FFPE) using either discrete spin columns or dedicated 96-well filter plates. The simplicity and efficacy of Chromatrap ChIP assays, enabling more IPs from less material, more quickly than traditional methods...

 

  Automation-Ready Blowdown Evaporator

The Ultravap Levante from Porvair Sciences is a next generation nitrogen blowdown evaporator designed to meet the needs of the modern automated laboratory.

Ultravap Levante RS232 connectionThe Ultravap Levante comes with an RS232 connection and a remote command set enabling it to connect to and be operated from most commercially available robotic liquid handling systems. Porvair have positioned this automation-ready microplate evaporator to appeal to the budget-conscious laboratory who may wish to automate their sample dry-down bottleneck in the future....

 

  Chromatrap Article Describes Methodologies for Increasing ChIP Efficiency

Chromatrap, a business unit of Porvair Sciences, has published a new technical article that discusses and describes methodologies to increase Chromatin Immunoprecipitation (ChIP) efficiency by making sure chromatin in your samples is sheared to the correct size range.

Chromatin ImmunoprecipitationThe authors describe how for every chromatin preparation it is essential to check the chromatin is sheared to fragments between 100-500 bp. They emphasise using a microfluidics platform is the most accurate measure of quantifying DNA. Problems associated with over or under sheared Chromatin fragments are discussed....

 

  Techniques for Increasing ChIP Efficiency

Chromatrap, a business unit of Porvair Sciences, has published a new technical article that discusses and describes methodologies to increase Chromatin Immunoprecipitation (ChIP) efficiency by making sure chromatin in your samples is sheared to the correct size range.

ChIPThe authors describe how for every chromatin preparation it is essential to check the chromatin is sheared to fragments between 100-500 bp. They emphasise using a microfluidics platform is the most accurate measure of quantifying DNA. Problems associated with over or under sheared Chromatin fragments are discussed and a protocol for optimised enzymatic shearing described.....

 

  Porvair Sciences Extend Range of High Performance PCR Plates

Porvair Sciences range of high performance PCR plates are made from polypropylene for extra rigidity.

High Performance PCR PlatesThese plates are compatible with the majority of 96- and 384-well block PCR and sequencing instruments, including fast sequencers and the (TM) RT-PCR machine. Manufactured under Class 10,000 clean room conditions the complete range of 13 microplates is certified free of pyrogens as well as DNAse and RNAse enzyme activity enabling optimised PCR results....

 

  Porvair Extend Range of PCR Plates

Porvair Sciences range of high performance PCR plates are made from polypropylene for extra rigidity.

PCR PlatesThese plates are compatible with the majority of 96- and 384-well block PCR and sequencing instruments, including fast sequencers and the Roche Light Cycler (TM) RT-PCR machine. Manufactured under Class 10,000 clean room conditions the complete range of 13 microplates is certified free of pyrogens as well as DNAse and RNAse enzyme activity enabling optimised PCR results....

 

  384-well Plates for Sample Storage / Assay Set-up

Porvair Sciences range of 384-well plates are produced in class 10,000 cleanroom conditions from superior grade, ultra-clean polypropylene to strict quality control guidelines.

384-well plateAvailable both sterile and non-sterile, Porvair 384-well plates provide a perfect solution for sample storage and assay set-up, allowing dilutions and aliquots to be simply handled, stored, or transported. Manufactured extra flat to ensure effective sealing, Porvair 384-well plates maintain your sample integrity over extended periods down to –80ºC....

 

  384-well Plates for Sample Storage & Assay Set-Up

Porvair Sciences range of 384-well plates are produced in class 10,000 cleanroom conditions from superior grade, ultra-clean polypropylene to strict quality control guidelines.

porvair mocroplatesAvailable both sterile and non-sterile, Porvair 384-well plates provide a perfect solution for sample storage and assay set-up, allowing dilutions and aliquots to be simply handled, stored, or transported. Manufactured extra flat to ensure effective sealing, Porvair 384-well plates maintain your sample integrity over extended periods down to –80ºC. Manufactured to conform to ANSI/SLAS plate dimensions all Porvair...

 

  Peer Review Research Demonstrates Benefits of Chromatrap Solid State ChIP Technology

Chromatrap reports on 3 further customer papers published in different prestigious peer reviewed journals, which cite how its proprietary solid state Chromatin Immunoprecipitation (ChIP) technology has enabled ground breaking research.

lab tech porvairA recent study published in Drug Metabolism & Deposition [1] looks at " The role of Chromatin structural changes in regulating human CYP3A ontogeny. Variability in drug metabolizing enzyme developmental trajectories contributes to inter-individual differences in susceptibility to chemical toxicity and adverse drug reactions, particularly in the first years of life. Factors linked to these inter-individual differences are largely unknown...

 

  New 96-well Purification Plate for Ultra-Pure DNA

ChromatrapÂŽ has announced a new 96-well high throughput purification plate for production of ultra-pure DNA.

96-well Purification Plate for Ultra-Pure DNAUsing proprietary filtration media that allow much higher loadings of active material than has been previously possible, typical assay times using the ChromatrapÂŽ DNA Purification Plate are less than 5 minutes. Buffers are optimised to remove any unwanted impurities while providing efficient DNA recovery from samples. The ChromatrapÂŽ DNA Purification Kit is designed for the purification and concentration of samples from PCR...

 

  Rapid Production of Ultra-Pure DNA

ChromatrapÂŽ has announced a new 96-well high throughput purification plate for production of ultra-pure DNA.

ChromatrapŽ DNA Purification PlateUsing proprietary filtration media that allow much higher loadings of active material than has been previously possible, typical assay times using the ChromatrapŽ DNA Purification Plate are less than 5 minutes. Buffers are optimised to remove any unwanted impurities while providing efficient DNA recovery from samples. The ChromatrapŽ DNA Purification Kit is designed for the purification and concentration of samples from PCR...

 

  Chromatrap Customer Focused Website Goes Live

Following extensive customer research, ChromatrapÂŽ has re-designed its website to better serve the needs of end users.

chromatrap websiteWith an expanding product range, new families of ChIP validated antibodies and a suite of useful new support information including articles, application notes, video tutorials and guides a new site was required. The bright, fresh new website layout makes it easier and quicker to find the ideal Chromatrap ChIP kit for your immunoassay. “We wanted a fresh approach” said Chromatrap Marketing Director...

 

  Robust Microplate for Genomics Sample Preparation

Porvair Sciences has announced that it will launch an exciting new microplate for genomics sample preparation at the forthcoming Analytica 2016 exhibition in Munich, Germany.

new microplate for genomics sample preparationDesigned with thickened walls and strengthened ribs underneath to stop cracking or leaking when used in Geno/Grinder or Tissulyser machines the robust 96-well 2ml deep well Genomics Sample Preparation Plate sets a new standard for high throughput genomics sample preparation. Unlike most commercially available deep well plates, the Genomics Sample Preparation Plate has been proven to...

 

  Automated Microplate Drying for Medicinal Chemistry

Porvair Sciences reports that a major Pharmaceutical company based in France has integrated its Ultravap Mistral blowdown evaporation system with a Hamilton Star robotic liquid handling system to enhance new drug candidate processing in its medicinal chemistry department.

Ultravap Mistral Using the Ultravap Mistral the pharmaceutical scientists have been able to remove the traditional ‘bottleneck’ of solvent evaporation from microplates by automated this time consuming step.  Set-up for unattended operation the Ultravap Mistral performs an evaporation every 20 minutes, and after each cycle, the level of liquid is checked by the robot and the needle depth is automatically modified to be about...

 

  Preparing Samples for Lab Automation

Porvair Sciences has announced it has chosen the ELRIG Symposium in Rennes, France (3-4th May 2016) to demonstrate its latest products that enable Lab Automation facilities to optimise sample preparation and improve productivity.

Ultravap MistralVisitors to the ELRIG Symposium will be able to see the Ultravap Mistral - a product designed to remove the traditional laboratory ‘bottleneck’ of solvent evaporation from microplates. Designed to be automation-friendly, the Ultravap Mistral gives significant throughput advantages to laboratories looking to optimise microplate sample preparation. Faster than centrifugal evaporation for single plates, significant increases in sample throughput are...

 

  Chromatrap launches Matched Antibodies & Primer Sets

Chromatrap announces that its high quality ChIP-validated antibodies can now be supplied with optimised matching primer sets.

chromatrap antibodiesUsing this out-of-box solution there is now no need to waste your valuable time searching databases and designing your own forward and reverse primers. Purchasing Chromatrap ChIP-validated antibodies with their matching high-quality primers, saves you time and gives you the confidence of using primers tested with the exact antibody and gene target with which you work. Many common epigenetic targets of interest...

 

  Matched ChIP-Validated Antibodies & Primer Sets

Chromatrap announces that its high quality ChIP-validated antibodies can now be supplied with optimised matching primer sets.

ChromatrapUsing this out-of-box solution there is now no need to waste your valuable time searching databases and designing your own forward and reverse primers. Purchasing Chromatrap ChIP-validated antibodies with their matching high-quality primers, saves you time and gives you the confidence of using primers tested with the exact antibody and gene target with which you work.
 Many common epigenetic targets of...

 

  Black Storage Plate for Light Sensitive Samples

Available from Porvair Sciences is a black 96-well deep well plate, offering a working volume of 1ml per well, that in conjunction with black sealing films ensures that light sensitive assays and samples are not degraded by exposure to light, even over long-term storage periods.

Black Storage PlateManufactured from polypropylene, Porvair's black deep well microplate has excellent heat and solvent resistant qualities. Using only ultra-pure grade polymer means that the black deep well plate has near zero leachates ensuring long-term sample integrity.  The black plate is fully validated RNase and DNase free allowing it to be used with even the most sensitive biological samples. Benefiting from a cylindrical well...

 

  Porvair Sciences Krystal UV Assay Microplates

Krystal UV quartz bottomed microplates from Porvair Sciences Ltd. are designed for high throughput applications which require excitation or detection wavelengths in the far UV region below 350nm.

Krystal UV quartz bottomed microplates.Made from highly polished fused quartz - Krystal UV plates are suitable for the most demanding cell-based assay requiring monitoring in the UV region down to 200nm. Direct quantitation of DNA/Protein rations at 260, 280 and 240nm is possible through use of these plates. Designed to exhibit low auto fluorescence, Krystal UV plates are available in 96- and 384-well plate designs, both compliant with ANSI/SLAS standards...

 

  Simple & Efficient Protocol for Native Chromatin Immunoprecipitation

Chromatrap, a business unit of Porvair Sciences, announces a new patented protocol that is able to simply, quickly and efficiently enrich transcription factors from Native Chromatin.

chromatrap imageNative Chromatin Immunoprecipitation (N-ChIP) is an alternative to traditional cross-linked (X-ChIP), which removes the need for fixing cells with formaldehyde prior to extraction. As a consequence the cells remain in a more natural 'native state'. The DNA/protein fragments are selectively immunoprecipitated using antibodies directed against the protein of interest and the resulting fractions treated to separate the DNA and...

 

  Sample Evaporators and Microplate Products for LC/MS

Porvair Sciences offer a range of sample evaporators and microplate products optimised for use in conjunction with LC/MS and LC/MS/MS instrumentation.

UltraVapTo facilitate better analysis of very dilute samples by LC/MS, Porvair Sciences nitrogen blowdown evaporators can assist by evaporating solvent to increase concentration thereby increasing sensitivity. In applications where serum or plasma samples have been de-proteinated using a protein precipitation microplate, such as the Porvair P3 plate, the sample is typically left in acetonitrile. Porvair evaporators provide a quick and...

 

  Epigenetics in Drug Discovery

Chromatrap®, a business unit of Porvair Sciences, has announced that it will be the Lead Sponsor at the prestigious “Epigenetics in Drug Discovery” conference to be held in Cambridge, UK from 26th-27th January 2016.

Epigenetics in Drug DiscoveryViewed as a new frontier in drug discovery, rapid progress has been made in enhancing understanding of epigenetic mechanisms of both new and existing drugs. With the processes that control epigenomic function providing new opportunities, epigenetics targets are enabling the discovery of novel drugs. At the conference - Dr Amy Beynon will deliver a presentation highlighting the use of new Chromatrap solid state ChIP...

 

  Sample Preparation for LC/MS

Porvair Sciences offer a range of sample evaporators and microplate products optimised for use in conjunction with LC/MS and LC/MS/MS instrumentation.

UltravapTo facilitate better analysis of very dilute samples by LC/MS, Porvair Sciences nitrogen blowdown evaporators can assist by evaporating solvent to increase concentration thereby increasing sensitivity. In applications where serum or plasma samples have been de-proteinated using a protein precipitation microplate, such as the Porvair P3 plate, the sample is typically left in acetonitrile. Porvair evaporators provide a quick and easy-to-use method of removing the acetonitrile...

 

  Twin Head Blowdown Evaporator Doubles Productivity

Porvair Sciences has announced the MiniVap™ Gemini - an all new entry-level product designed to remove the solvent from two microplates simultaneously.

MiniVap GeminiUsing a highly efficient evaporator head technology and an innovative manifold design, which directly injects heated nitrogen into each well of two 96-well microplate simultaneously, the MiniVap Gemini enables researchers to remove the traditional laboratory ‘bottleneck’ of solvent evaporation from microplates prior to analysis or reconstitution in buffer. The productive MiniVap™ Gemini has been designed to accommodate any ANSI / SLAS footprint 96-well...

 

  High Quality Specific ChIP-validated Antibodies

Chromatrap, a business unit of Porvair Sciences Ltd, has announced the launch of its own range of Chromatin Immunoprecipitation (ChIP)-validated antibodies.  

chromatrap visualBuilding on the company’s success in the solid-state ChIP market, which underpins modern epigenetic research, the addition of ChIP-validated antibodies further enhances the high performance application solutions that Chromatrap can provide researchers. Chromatrap Product Development Manager, Dr Amy Beynon commented “The use of high quality and specific ChIP-validated antibodies is essential for the success of a ChIP assay...

 

  Chromatrap ChIP-seq Protocol Yields Improved Results

ChromatrapÂŽ, a business unit of Porvair Sciences, has developed a new protocol that further extends the many advantages of its popular Chromatin Immunoprecipitation Sequencing (ChIP-seq) assay kits.

porvair imageKey developments for the Chromatrap® ChIP-seq kit (version 1.2) include high quality chromatin can now be achieved via sonication or enzymatic digestion ; high and low abundant enrichment is possible from small chromatin samples ; improved antibody binding ; greater chromatin loading flexibility and the ability to use increased slurry volumes for difficult samples. Chromatrap’s® ChIP-seq kit uses solid state technology...

 

  Top 10 Tips for ChIP Sequencing Library Preparation

Chromatrap®, a business unit of Porvair Sciences, has produced an informative new guide entitled ‘Top 10 Tips for ChIP-seq Library Preparation'.

Top 10 Tips for CHIPChIP-sequencing, also known as ChIP-seq, is a method used primarily to determine how transcription factors and other chromatin-associated proteins influence phenotype-affecting mechanisms. Determining how proteins interact with DNA to regulate gene expression is essential for fully understanding many biological processes and disease states. ChIP-seq combines chromatin immunoprecipitation (ChIP) with massively parallel DNA sequencing to identify...

 

  New Guide for Optimising ChIP Sequencing Library Preparation

Chromatrap®, a business unit of Porvair Sciences, has produced an informative new guide entitled ‘Top 10 Tips for ChIP-seq Library Preparation'.

Chromatrap 10 tipsChIP-sequencing, also known as ChIP-seq, is a method used primarily to determine how transcription factors and other chromatin-associated proteins influence phenotype-affecting mechanisms. Determining how proteins interact with DNA to regulate gene expression is essential for fully understanding many biological processes and disease states. ChIP-seq combines chromatin immunoprecipitation (ChIP) with massively parallel DNA sequencing to identify...

 

  Selecting the Correct Assay Plate

Correct assay plate selection is vital for successful research, whether you are performing absorbance, fluorescence or luminescence assays.

assay platesPorvair Sciences offers a wide range of assay plates which are recognized as industry-leading tools for Pharma drug discovery and screening.
A new guide, contained within an updated assay plates mini catalogue, has been produced by Porvair to provide information and guidance on how to choose the correct assay plate for your research. By carefully selecting the correct plate type for your assay, it is possible to significantly improve results. By following the simple instructions set out in the...

 

  Clear Bottom Assay Plates

The unique Krystal 2000 microplate range from Porvair Sciences has been optimised for luminescence and fluorescence assays.

clear bottom assay platesA patented manufacturing process, using a ‘two-shot’ mould, provides clear, individual wells in an opaque matrix. The special design of the plate totally eliminates the well-to-well optical crosstalk inherent with other clear bottomed microplate designs, giving unmatched accuracy, sensitivity and repeatability of photometric readings. Very high signal-to-noise ratio and low detection limits can be achieved with this superb plate. All tissue-culture treated plates are supplied...

 

  Efficient, Sensitive and Robust Chromatin Immunoprecipitation Methods

ChromatrapŽ, a business unit of Porvair Sciences, has produced a new 10-page brochure that provides an informative introduction to chromatin immunoprecipitation (ChIP) technology and a detailed comparison of traditional bead based and ChromatrapŽ solid state ChIP technologies.

ChromatrapÂŽ ChIP kitsChromatrapÂŽ ChIP kits use revolutionary spin columns or microplates which contain discs of an inert, porous polymer to which protein A or G has been covalently attached. This patented format is unique. During an assay, the chromatin/antibody complex is selectively retained by the disc. Flushing with three buffers and an elution step are all that is required to obtain the selectively enriched DNA, making ChromatrapÂŽ more efficient in the laboratory. With a fast processing time of...

 

  New Modern Microplate Evaporator

The Ultravap Levante™ is a new introduction to Porvair Sciences’ popular series of nitrogen blow-down sample concentrators and evaporators. 

Ultravap LevanteUsing technology from the successful Ultravap Mistral™ series of robot-ready, integration compatible evaporators Porvair have re-designed the classic single plate evaporator to meet the needs of the modern laboratory. The Ultravap Levante makes it even easier to integrate an automatic dry down step into your biological sample preparation protocol. With the needs of LC/MS users very much in mind, the Ultravap Levante offers rapid programmable dry down of samples dissolved in...

 

  ChIP-seq Assay Kit Helps Understanding of Protein-DNA Regulatory Network

ChromatrapŽ, a business unit of Porvair Sciences, has published a new application note that describes how ChromatrapŽ ChIP-seq assays now enable unbiased, genome-wide understanding of protein-DNA regulatory networks. 

ChIP-seq Assay KitGenome-wide mapping of protein-DNA interactions is essential for a complete understanding of gene regulation. A detailed map of epigenetic marks and transcription factor binding is necessary for deducing the regulatory networks that underpin gene expression in a variety of biological systems. The most widely used tool for examining these interactions is ChIP followed by massively parallel sequencing (ChIP-seq). The new application note reports on how the Chromatrap...

 

  Optimised ChIP Protocols for qPCR and Sequencing

ChromatrapÂŽ, a business unit of Porvair Sciences, has announced a new web page that brings together protocols developed using their proprietary solid state chromatin immunoprecipitation (ChIP) technology.

ChIP assaysThe new web page provides scientists with optimised ChIP methodologies for qPCR, high throughput qPCR, sequencing, high throughput sequencing and enzymatic chromatin shearing using ChromatrapŽ  kits. ChromatrapŽ is a ground breaking technology that offers a quicker, easier and more efficient way of undertaking ChIP assays. ChromatrapŽ kits for qPCR use revolutionary ChromatrapŽProtein-A or Protein-G spin columns which contain...

 

  Highly Efficient ChIP Assay Kit for FFPE Samples

ChromatrapŽ, a business unit of Porvair Sciences, has introduced a new Formaldehyde Fixed Paraffin-Embedded (FFPE) ChIP Kit which overcomes the widely acknowledged shortfalls of the technique.

ChIP analysisDue to the cross-linking of proteins by formaldehyde, FFPE tissues have traditionally presented a particular challenge for ChIP analysis. In addition, the small size and delicate nature of the tissue, and the difficulty in extracting samples from paraffin, used to provide tissue support after preservation, can damage complex cellular complexes such as chromatin. ChIP assays from these samples until now have therefore proved time consuming and difficult...

 

  Optimised Solid Phase Extraction of Polar Compounds

Porvair Sciences offers a range of products that enable optimised Solid Phase Extraction (SPE) of polar compounds. 

porvairThis includes a new C18 silica packed Microlute™ plate, vacuum manifolds, collection plates and solvent evaporators all designed to streamline your sample preparation. The new C18 Microlute plate offers good separation of a wide range of polar compounds which are not attracted to the C18 tail. MicroLute™ is the original 96-well format SPE plate proven in labs worldwide. The plate provides all the advantages of automated and...

 

  High Throughput ChIP-seq Assay for Genome-wide Protein-DNA Analysis

ChromatrapŽ, a business unit of Porvair Sciences, has published a new application note that describes how ChromatrapŽ ChIP-seq assays now enable unbiased, genome-wide understanding of protein-DNA regulatory networks. 

porvair chemistGenome-wide mapping of protein-DNA interactions is essential for a complete understanding of gene regulation. A detailed map of epigenetic marks and transcription factor binding is necessary for deducing the regulatory networks that underpin gene expression in a variety of biological systems. The most widely used tool for examining these interactions is ChIP followed by massively parallel sequencing (ChIP-seq). The new application note reports on how...

 

  High Throughput ChIP Sequencing

ChromatrapÂŽ, a business unit of Porvair Sciences, has announced a major product launch at the European Human Genetics Conference (Glasgow, UK) and the Festival of Genomics (Boston, USA) on the 6th June 2015 and 22nd-24th June 2015 respectively.

chromatrapVisitors to ESHG Stand 268 and Festival of Genomics Booth 18 will be able to see a new high-throughput ChIP Sequencing product and learn about Chromatrap's latest developments in solid state Chromatin Immunoprecipitation (ChIP) technology. Chromatrap’s® new ChIP-seq kit utilises the company's proprietary solid state technology in parallel with high throughput sequencing to deliver a streamlined ChIP-seq protocol from small cell...

 

  Application Optimised Microplate Products at ACHEMA

Visitors to ACHEMA 2015 have been invited by Porvair Sciences to Stand F44 in Halle 4.2 to see their expansive range of application optimised microplates and microplate equipment.

ultrawrap mistralFor labs involved with fraction collecting, compound storage, plate replication and mixing applications - Porvair has developed a genuine 2.00 ml 96 round well deep well plate that enables scientists to use the full 2.00 ml well capacity. Manufactured under class 10,000 conditions from ultra-pure grade polypropylene the 2.00ml 96 ROUND well deep well plates are certified as RNase / DNase free and contain no measurable contaminants that could otherwise leach out and affect the sample...

 

  Porvair Launch uHPLC Storage Plate

Porvair Sciences glass vial storage plate combines 96 borosilicate glass vials of 700¾l into a rigid polypropylene carrier microplate to provide a superior product for storage and transportation applications.

 uHPLC storage plateThis extremely hard wearing plate provides a zero-leachates solution for UHPLC and also for storage scenarios such as combinatorial chemistry where broad chemical resistance and thermal stability is vital. Porvair glass vial storage plates are less costly than solid glass plates and are precisely manufactured to comply with ANSI/SLAS dimensions to ensure complete compatibility with automated equipment. To prevent evaporation or...

 

  96-well Glass Vial Storage Plate for UHPLC

Porvair Sciences glass vial storage plate combines 96 borosilicate glass vials of 700¾l into a rigid polypropylene carrier microplate to provide a superior product for storage and transportation applications.

96-well Glass Vial Storage Plate for UHPLCThis extremely hard wearing plate provides a zero-leachates solution for UHPLC and also for storage scenarios such as combinatorial chemistry where broad chemical resistance and thermal stability is vital. Porvair glass vial storage plates are less costly than solid glass plates and are precisely manufactured to comply with ANSI/SLAS dimensions to ensure complete compatibility with automated equipment. To prevent evaporation...

 

  Polypropylene PCR Plates

To ensure full compatibility with robotic systems, DNase / RNase- and pyrogen-free PCR plates from Porvair Sciences feature high rigidity to minimise distortion before and after thermal cycling.

Polypropylene PCR plates Produced in Class 10,000 clean room conditions – Porvair range of PCR plates are certified free of pyrogens as well as DNAse and RNAse enzyme activity enabling routine achievement of excellent PCR results. Porvair PCR plates are based upon a well design where the liquid meniscus comes below the plate surface eliminating sample carryover problems when using a plate lid.
Summarised in an easy-to-use selection guide...

 

  Entry Level Microplate Solvent Evaporator

The MiniVap™ blowdown evaporator from Porvair Sciences takes just minutes to remove volatile organic solvents from your 96-well microplates.

porvairThe MiniVap™ is the perfect tool for labs where smaller numbers of individual plates need drying. Incorporating advanced evaporator head technology and an innovative manifold design, which directly injects heated nitrogen into each well of a 96-well microplate simultaneously, the MiniVap enables researchers to remove the traditional laboratory ‘bottleneck’ of solvent evaporation from microplates prior to analysis or reconstitution in buffer...

 

  Streamlining ChIP for qPCR Analysis

ChromatrapÂŽ, a business unit of Porvair Sciences, has an announced solid state ChIP kits which rapidly improve chromatin immunoprecipitation (ChIP) through a unique patented technology that streamlines the process, ensuring chromatin preparation to qPCR analysis can be performed in under five hours.

porvairChromatrapŽ is a ground breaking technology that offers a quicker, easier and more efficient way of undertaking ChIP assays. ChromatrapŽ kits for qPCR use revolutionary ChromatrapŽProtein-A or Protein-G spin columns which contain discs of an inert, porous polymer to which protein A/G has been covalently attached. During an assay, the chromatin/antibody complex is retained by the disc. Flushing with three buffers and an elution step are...

 

  Space Saving 96-Well Deep Well Plate

Porvair Sciences low profile 96-well deep well plate achieves a storage volume of 1.1ml / well in a height of just 27 mm enabling more plates to be stacked or stored in a given space.

porvairpr415Manufactured from extractables-free polypropylene in an ISO 10,000 approved clean room environment - Porvair low profile plates undergo extensive quality testing to ensure they are of the highest quality, certified free from DNase, RNase and endotoxin contamination. Combining an affordable price with uncompromising high quality, Porvair low profile 96-well deep well plates are precisely manufactured to comply with...

 

  Tissue Culture Plastics & Epigenetic Supplies

Porvair Sciences has released a new 2015 catalogue that describes its popular range of high quality tissue culture treated plastics and consumable products for Epigenetics.

porvairPorvair Tissue Culture plastics are made to the highest international standards for material quality, surface optical polish, tissue culture treatment, sterility and pack integrity. All products are certified to be free from DNA/RNA, DNase/RNase and Pyrogen contamination. Investment in UK based laboratory testing ensures that you receive consistently high quality products. Complementing its tissue culture treated flasks...

 

  Rapid & Simple SPE Methods Development

The Development Microlute™ from Porvair Sciences is a Solid Phase Extraction (SPE) microplate which provides a wide assortment of phase chemistries and sorbent loadings in a single plate making it ideally suited for method development.

microplateOffering scientists a choice of up to 12 different phases and sorbent loadings (10 -100mg) in a standard format 96-well plate the Development Microlute™ allows you to simply and rapidly screen for the optimal retention and selectivity required to achieve your sample preparation objectives. By providing a complete SPE methods development solution that does not need to be constructed by the user, the Development Microlute™ delivers...

 

  Automated Microplate Drying Workstation

ÂŁ1000 trade-in value on any evaporator system against the purchase of a new UltraVap Mistral

UltraVap MistralThe UltraVap Mistral from Porvair Sciences makes it easy to integrate an automatic dry down step into your automated liquid handling protocol. Optimised to work with most commercial robotic liquid handling systems the UltraVap Mistral represents the leading edge in automated microplate drying technology.  Until 30th November 2014 - Porvair Science is offering a £1000 trade-in value on any evaporator system against the purchase of a new UltraVap Mistral....

 

  ChIP Sequencing Kit for Next Generation Sequencing

Porvair Sciences has developed a new ChIP sequencing assay kit extending the benefits of their proprietary ChromatrapŽ solid state ChIP technology to preparation of purified Chromatin for the generation of sequencing libraries.

porvairpr405-image copyChromatin immunoprecipitation (ChIP) is a technique used to detect interactions between proteins and DNA, and is based on the enrichment of DNA associated with a specific protein of interest. Combining ChIP with massively parallel sequencing (ChIP-seq) allows the accurate survey of interactions between proteins and DNA, enabling the study of epigenetic marks which is essential for a full understanding of...

 

  ChromaTrap Helps Advance Research into Women`s Reproductive Health

An informative video interview with Professor Steve Conlan of the College of Medicine at Swansea University (UK) highlights the latest research developments in women’s reproductive health using unique molecular biology tools.

 

  Automation Compatible 10ml Microplates

Porvair Sciences 24-well deep well plates permit  users to simply undertake multiple, high volume (10ml / well) experiments in a single unit maximising both productivity and  operational flexibility. 

microplateThe 24-well plates are constructed of high grade, low extractable polypropylene, which imparts excellent temperature and  chemical resistance making them the perfect tool for applications including  serial dilution, mixing, reaction chemistry and cell culture growth. The  wells are square with a conical base to optimise sample concentration and  recovery...

 

  High Volume Microplates Precisely manufactured to SLAS/ANSI specifications

Porvair Sciences 24-well deep well plates permit users to simply undertake multiple, high volume (10ml / well) experiments in a single unit maximising both productivity and operational flexibility.

horiba nanoThe 24-well plates are constructed of high grade, low extractable polypropylene, which imparts excellent temperature and chemical resistance making them the perfect tool for applications including serial dilution, mixing, reaction chemistry and cell culture growth. The wells are square with a conical base to optimise sample concentration and recovery. The plate dimensions are precisely manufactured to SLAS/ANSI specifications making them... 

 

  Introduction to Solid State ChIP Technology

A new instructional video from Porvair Sciences explains exactly how to conduct a ChIP assay for epigenetic research starting from a confluent monolayer of human cells.

porvairpr401This live demonstration of the Chromatin Immunoprecipitation (ChIP) assay uses Porvair’s innovative solid-state ChIP kit – Chromatrap 96. The video was prepared to inform researchers of an optimised protocol for preparing fresh chromatin from a dish of growing cells and how to verify the quality of the chromatin recovered...

 

  New Multilayer Flask Enhances Cell Culture Production

Porvair Sciences has announced a new 5-layer cell culture flask developed to fulfil the need of the growing number of applications that require large numbers of cells. 

porvairpr402While single layer flasks are well proven for small-scale cell culture scale up, their use can become laborious and time-consuming when large numbers of cells are required. Offering a sterile growth area of 870cm2 in a compact footprint - Porvair's new 5-layer cell culture flask offers a high performance solution to this application need...

 

  Enrichment of Highly Abundant Epigenetic Marks from Endometrial Stromal Cells

ChromatrapŽ, the novel solid-based matrix for chromatin immunoprecipitation (ChIP) assays, available from Porvair Sciences, has been successfully used to isolate high quality chromatin from difficult biopsy material.

porvairpr400Focusing on the precipitation of epigenetic marks from primary endometrial stromal cells, researchers have produced excellent enrichment of high abundant epigenetic marks from 1 million cells isolated from a tissue biopsy. The selective enrichment using Chromatrap was highlighted by the selective amplification of both positive and negative gene targets relative to negative IgG. Further the work described demonstrates how the Chromatrap ChIP Assay Kit is able to delineate the balance between active and repressive associated marks and also is compatible with human tissue...

 

  Video Introduction to Automated Microplate Sample Drying

Porvair Sciences has announced a new video that provides an informative introduction to the Ultravap Mistral - a next generation robot-compatible dry down station designed to remove the 'bottleneck' of solvent evaporation from microplates.

porvair videoDrawing upon Porvair’s market leading position in nitrogen blow down evaporation – the UltraVap Mistral offers a simple, turnkey solution for integrating an automatic dry down step into your automated liquid handling protocol.  The UltraVap Mistral is fully optimised to work with robotic liquid handling systems from suppliers including Beckman, Hamilton and Tecan and features a “shuttle” design capable of serving and retrieving microplates to and from the robot deck without further need for off-deck handling....

 

  ChromaTrap Receives Positive Commentary in Cited Research

Porvair Sciences reports on positive commentary by researchers in published papers citing how using the fast, sensitive ChromaTrap™ Chromatin Immunoprecipitation (ChIP) technology has benefited their research.

ChromaTrap Receives Positive Commentary in Cited ResearchIn a paper by C.R Williams et al (Am J Physiol Cell Physiol 303: C213–C223, 2012) - Chromatrap was used to assess the occupation of NFkB p65 onto the Nox4 promoter in human aortic endothelial cells which had been treated with normal and high glucose. ChIP data using Chromatrap pro A spin columns demonstrated that in high glucose concentrations NfkB binding to the Nox4 promoter was increased when compared to normal glucose concentrations and rosiglitazone attenuated NfkB binding to the promoter. Their findings illustrated that NFkB/p65-Nox4 axis as an important target of rosigliatzone in vascular endothelial cells following hyperglycemia...

 

  New Guide to Improving Your ChIP Assay Results

Porvair Sciences' has produced an informative new guide entitled ‘Top 10 tips for positive ChIP results’.

ChIP Assay ResultsThe success of a Chromatin immunoprecipitation (ChIP) assay is highly dependent on the quality of chromatin prepared.  Written by scientists with many years experience of ChIP, the new 8-page document provides an informative 10-point illustrated guide to help you improve your ChIP assay results. ChIP is a commonly used immunprecipitation technique for mapping the DNA-protein interactions in cells which are crucial for correct gene regulation. In a ChIP assay  DNA-protein complexes (Chromatin) are selectively immunoprecipitated using....

 

  Double O-ring Ensures High Integrity Cap Mat Seal

Porvair Sciences has introduced new silicone cap mats for its range of 2ml deep well storage blocks.

Double O-ringIncorporating a novel double O-ring feature - the new silicone cap mats ensure a tight liquid proof seal every time. Such is the quality of the seal that capped storage blocks can be shaken, inverted or frozen without any loss of stored sample integrity. Manufactured under class 10,000 clean room conditions from high grade silicone, which is resistant to most solvents, the new cap mats contain no contaminants that may leach out and affect stored sample.....

 

  Comprehensive Microplate & Microplate Equipment Catalogue

Porvair Sciences' product catalogue for 2013-2014 is packed with vital information on the company's wide range of microplates, plate sealers and microplate evaporators to help you get the best from your separations, assays and storage applications.

Microplate Equipment CatalogueThe comprehensive 96-page catalogue combines the most reliable microplate instruments with high quality microplates and related consumables to provide a one-stop reference source for all your microplate needs. Porvair's comprehensive microplate range includes polystyrene assay plates, clear and solid bottomed plates, polypropylene storage plates (deep and shallow well), vacuum manifolds, manual as well as electro-pneumatic plate sealers and nitrogen blow down evaporators....

 

  Specialist Microplate Products for Life Sciences

Porvair Sciences has announced that it will be showing its latest specialist microplates and microplate equipment at the forthcoming Pittcon 2014 (Chicago), Analytica 2014 (Munich) and Genomics Research 2014 (San Francisco) exhibitions.

Specialist Microplate Products for Life Sciences

Visitors to Pittcon Booth 4021 and Analytica Stand B2.320A will be able to see Porvair’s complete range of automation friendly microplates and equipment. On display will be the Ultravap Mistral - Porvair's new generation robot-compatible nitrogen blow down station. For many years, Porvair Sciences has led the field in nitrogen blow down evaporation. The UltraVap Mistral makes it even easier to integrate an automatic dry down step into your automated liquid handling protocol. Combining uncompromising high quality with an affordable price...

 

  ChIP Enzymatic Shearing Kit

Porvair Sciences has announced a new Chromatrap Enzymatic Shearing Kit that contains all the necessary reagents and buffers for up to 10 chromatin preparations.

Chromatrap Enzymatic Shearing Kit

The success of a ChIP assay is highly dependent on the quality of chromatin prepared.  The Chromatrap® enzymatic shearing kit  - allows you to determine optimal shearing conditions for your chromatin preparations and can supply you with enough chromatin to perform up to 24 ChIPs if using standard Chromatrap® ChIP spin column kit or up to 96 IP’s if using Chromatrap®  ChIP 96 High throughput microplate. Chromatin immunoprecipitation (ChIP) is a technique used to study the association of specific proteins,or their modified isoforms, with defined genomic regions...

 

  Epigenetics Researchers Enthuse Over ChromaTrap ChIP technology

Porvair Sciences reports strong growing demand for their ChromatrapÂŽ chromatin immunoprecipitation (ChIP) assay technology from academic groups and biopharmaceutical organisations involved with epigenetic research.

ChromatrapÂŽ 96 HT solid-state ChIP

Stephen Knight, Sales and Marketing Director commented "An expanding number of proven application solutions and the introduction of the ChromatrapŽ 96 HT solid-state ChIP high throughput platform has enabled us to more than double the number of research groups using ChromaTrap assay technology during the last 12 months".  He added "We are particularly pleased by the very positive feedback from early adopters of the technology"...

 

  Adaptable Semi-Automatic Microplate Sealer

The MiniSeal II semi-automatic microplate sealer from Porvair Sciences comes complete with adapters enabling it to process deep well, shallow well, low profile deep well, filter and assay plates that conform to the ANSI / SLAS standard format.

Adaptable Semi-Automatic Microplate Sealer

MiniSeal II plate adaptors not currently in use are ingeniously designed to stack on top of the unit to keep them readily available. The MiniSeal II heat sealer operates with a very high force, this together with a powerful 450W heater ensures high integrity sealing of almost any type of microplate. With so much available power, sealing times for most polypropylene plates with Porvair seals are less than 3 seconds each....

 

  Compact Multiple Format Laboratory Mixer

Porvair Sciences has introduced the Co-Mix - an accurate, reliable, compact and simple-to-use multi-format mixer.

Compact Multiple Format Laboratory Mixer

Operated via an intuitive touchscreen the Co-Mix offers effortless changing between mixing of 96- and 384-well microplates in skirted, semi-skirted and unskirted variants plus deep-well plates and PCR tubes / strips.  An innovative plate holding mechanism ensures smooth manipulation of microplates eliminating sample spillage and cross-contamination problems. A vortex module enables mixing of numerous tube formats including micro test tubes...

 

  Porvair Expands Tissue Culture Plasticware Range

Porvair Sciences has announced new additions to its popular range of high quality tissue culture (TC) treated laboratory plasticware.

Porvair Tissue Culture Plastic Range

Complementing its tissue culture treated flasks, dishes, syringe filters, centrifuge tubes and microplates – Porvair has added new ranges of affordably priced, top quality pipettes, micro-pipettes, pipette fillers, filter tips and cell scrapers. Porvair TC-plastics are made to the highest international standards for material quality, surface optical polish, tissue culture treatment, sterility and pack integrity. All products are certified to be free from DNA/RNA, DNase/RNase and Pyrogen contamination. Investment in UK based laboratory testing ensures that you receive consistently high quality products...

 

  Porvair Launches High Throughput ChIP Assay Plate

Porvair Sciences has announced that it will officially launch Chromatrap®96 HT – an innovative 96-well chromatin immunoprecipitation (ChIP) assay plate at Epigenomics of Common Diseases (Wellcome Trust, Cambridge, UK) from 7th-10th November 2013.

Porvair Sciences has announced that it will officially launch ChromatrapÂŽ96 HTThe ChromatrapÂŽ96 HT is a new high throughput ChIP microplate based on the novel spin-column ChIP technology. It is essentially 96 separate Chromatrap spin-columns in one device designed to enable researchers to perform up to 96 ChIP experiments in parallel. Assays can be performed either by using hand-held multichannel pipette or by using automated liquid handling robots for even higher throughputs...

 

  Ultra-Flat Glass Bottom Plates Optimise Imaging of Growing Cells

Porvair Sciences new generation Krystal™ glass bottom plates are precision manufactured using a proprietary process resulting in excellent light transmission and an ultra-flat optical plane (+/- 15µm) making them perfect for imaging growing cells.

Krystal glass bottom plates

The complete range of 24-, 96- and 384-well Krystal glass bottom microplates is available sterilised for tissue culture to optimise cell growth or non-sterile for assay development. Deep black plates for fluorescent studies are available, together with brilliant white plates which increase sensitivity for luminescence and absorbance work. The high optical clarity base of each plate in the range offers the advantage of easy positioning and crisp images when used with confocal microscopes....

 

  New Starter Kit for SPE Sample Preparation

Porvair Sciences has announced the Microlute SPE sample preparation starter kit.

Microlute SPE sample preparation starter kit

This kit contains everything needed to begin productive SPE sample preparation in a 96 well plate format, including two development filter plates and a popular C18 sorbent filter plate, 2ml collection plates, disposable waste trays and, most importantly, the Microlute Acrylic Vacuum Manifold. The new starter kit offers all the advantages of SPE sample preparation in a convenient microplate format, capable of rapidly processing 96 samples in one run, repeatedly and precisely. All that is required for full operation is a suitable laboratory vacuum connection or pump...

 

  Porvair Launches Genuine 2ml Deep Well Plate

Porvair Sciences has developed the first 96-well round deep well plate that genuinely delivers 2.00 ml liquid capacity / well in an automation compatible SLAS / ANSI footprint.

2ml deep well plate

The revolutionary "common wall" design provides a full 2ml round well, round bottom well within a 45mm height limit, thus ensuring full compatibility with most plate handling equipment. Unlike other '2ml' deep well plates that typically offer just 1.80-1.90ml / well,  the new Porvair plate enables labs involved with fraction collecting, compound storage, plate replication and mixing applications the chance to use the full 2.00 ml well capacity without compromise. Manufactured under class 10,000 conditions from ultra-pure grade polypropylene, Porvair's new 2.00ml 96-well deep well plates are certified as RNase / DNase free and contain no measurable contaminants that could otherwise leach out and affect the sample...

 

  Fast Access to High Microplate Sample Integrity

Porvair Sciences has launched a new online service providing organisations with easy access to next day delivery on competitively priced, high performance microplate thermal seals.  For laboratories in the UK choosing to use the new service all microplate seals are also delivered free-of-charge.

Microplate Seal - Online Service

Available in a wide choice of colour-coded designs - Porvair microplate thermal seals are available optimised for use with all brands of assay plates. These easy to use thermal seals work with all commercially available heat sealers that take pre-cut strip seals. They are printed in five different colours and marked “This way up” to ensure easy selection of the right gauge of seal and correct positioning on the microplate.  Seals are compatible with most heat sealers...

 

  Large Volume Plates for Storage and Transport Applications

Porvair Sciences offers a range of high quality, large volume microplates (5ml, 7ml and 10ml) to meet the special requirements of storage / transport applications in combinatorial chemistry, environmental and food technology markets.

Large volume microplate

Produced under class 10,000 clean room conditions from virgin polypropylene, each 24-well (10ml) and 48-well (5ml and 7ml) plate contains no contaminants that may leach out and affect the samples being stored or transported. All these large volume plates can be heat sealed or capped with flexible polymer “cap mats” to enable high integrity storage of samples for prolonged periods at -80°C....

 

  New Robot-Compatible Automatic Dry Down Station

Porvair will officially launch the UltraVap Mistral robot-compatible automatic dry down station at Drug  Discovery 2013 (Manchester, UK) and Biotechnica 2013 (Hannover, Germany)

Porvair-UltravapMistralDrawing upon Porvair’s market leading position in nitrogen blow down evaporation – the UltraVap Mistral offers a simple, turnkey solution for integrating an automatic dry downstep into your automated liquid handling protocol.  The UltraVap Mistral is fully optimised to work with robotic liquid handling systems from suppliers including Beckman, Hamilton and Tecan and features a new “shuttle” design capable of serving and retrieving microplates to and from the robot deck without further need for off-deck handling.

 

  Reference Guide to Microplate Chemical Compatibility

Porvair Sciences has announced a new version of its Chemical Compatibility Chart that provides an easy-touse reference guide detailing the chemical resistance of membranes and matrices used in microplates to a wide range of common laboratory chemicals.

Porvair Catalogue

Employing tests performed at room temperature (25°C) - Porvair has compiled data as to the compatibility of different microplate matrices and membranes to a wide range of acids, alcohols, bases, esters, hydrocarbons /chlorinated hydrocarbons, ketones and other chemicals. In the tabulated chart - chemical compatibility data for each microplate material is listed as ‘suitable’, ‘ok for medium term use’ or ‘unsuitable’ thereby offering lab scientists the information to enable selection of just microplates constructed from materials optimised for their application...

 

  North American Microplate Catalog

Porvair Sciences has announced the first North American edition* of its internationally trusted ‘Catalog of Microplates and Microplate Equipment’.

Porvair Catalogue

Many scientists around the world have come to rely upon the Porvair Sciences catalog as a trusted source of information that enables them to choose the optimum microplate, microplate evaporator or sealer for their application. This new2013 edition brings together information on Porvair Sciences comprehensive microplate and microplate equipment product range that is available and supported by knowledgable local agents** through the USA and Canada. Reflecting Porvair's continuing commitment to continuous technological innovation, the North American catalog introduces a suite of exciting new products..

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  High Throughput ChIP Assay for Multiple Epigenetic Target Screening

Porvair Sciences has announced an application note describing the excellent results achievable from a new 96-well format version of its ChromaTrap chromatin immunoprecipitation (ChIP) assay technology.

Porvair ChromaTrap 96Developments in the field of epigenetics are rapidly expanding as researchers elucidate the principles governing gene regulation through the in vivo dynamic binding of proteins to DNA. Key to this is the need to analyse large numbers of high and low abundant regulatory mechanisms to systematically map protein-DNA interactions following pathogen/disease stimulus...

 

  Novel Microplate Design Eliminates Well-to-Well Crosstalk

To address performance limiting well-to-well crosstalk inherent in most assay plates – Porvair Sciences has developed the Krystal 2000 microplate range. 

Novel Microplates - Krystal 2000Incorporating unique individual clear cups molded into either a black or white polypropylene matrix – crosstalk is eliminated and the sensitivity, photometric accuracy and repeatability of your bottom reading absorbance, fluorescence and luminescence measurements markedly improved. Maintaining industry standard 96-well microplate dimensions the Krystal 2000 range is fully compatible with all commercially available plate readers, robotic sample processors and automated liquid handling systems...

 

  Chromatrap enriches epigenetic marks from primary cells

A new application note from Porvair Sciences details a protocol for its ChromatrapÂŽ ChIP assay kit that has been developed to enrich epigenetic marks from primary human tissue cells.

Chromatrap

ChromatrapÂŽ Pro-A, the novel solid-based matrix for chromatin immunoprecipitation assays (ChIP) has been successfully used for isolation of high quality chromatin from difficult biopsy material. Focusing on an application to precipitate epigenetic marks from primary endometrial stromal cells - results show high abundant epigenetic marks from 1 million cells isolated from a tissue biopsy, with selective amplification of positive gene targets relative to negative IgG and negative gene loci....

 

  Porvair Sciences Announces Summer Show Program

Porvair Sciences has announced that its latest applications focused microplates and microplate equipment will be exhibited at Forum LABO, European Lab Automation  ASMS and HPLC 2013

Porvair Exhibition StandVisitors to Porvair’s stands at these important events will be able to meet technical specialists, see the company's new UltraVap Mistral microplate evaporator, recently launched range of HPLC sample evaporators and review a wide selection of high quality microplates. Also available will be copies of new mini catalogues for Porvair’s deep well plates, assay plates plus a special catalogue dedicated to serving the North American market....

 

  Orbital Shaker Helps Accelerate Protein Precipitation Sample Preparation

Porvair Sciences has announced an online video demonstrating its MicroShake™ orbital shaker and how it can be used to accelerate sample preparation when using the company's popular p3 protein precipitation plates

porvairpr376By simply placing a p3 plate on the MicroShake™ dedicated plate holder and agitating for less than 30 seconds - rapid and complete mixing of serum samples with acetonitrile is ensured. The MicroShake™ has been rigorously tested with p3 plates to ensure that no breakthrough of supernatant liquid can occur and has been shown to be the fastest way to ensure protein precipitation throughout the sample....

 

  Porvair Speeds Up Evaporation of HPLC Solvents

Porvair Sciences announces new versions of its MiniVap and UltraVap blowdown evaporators that use warm air or nitrogen to speed up the evaporation of common HPLC solvents such as dichloromethane, methanol and acetonitrile from sample vials, significantly improving throughput and removing this common laboratory bottleneck

Porvair Speeds Up Evaporation of HPLC SolventsCombining a new 48-well needle head with a dedicated HPLC vial holder that accepts 48 standard 1.5ml vials* transforms any MiniVap or UltraVap system into a high throughput HPLC sample evaporator. Applications that will benefit from the new HPLC sample evaporators include pre-concentration prior to injection (to increase sensitivity) as well as evaporation to dryness of post-column fractions for recovery of compounds....

 

  Porvair Sciences Expands Product Range for Epigenetics

Porvair Sciences has announced the addition of the novel Chromatrap chromatin immunoprecipitation (ChIP) assay range to its portfolio of products for epigenetics

Porvair products for epigenetics research Developed in conjunction with Department of Life Sciences at University of Swansea, UK - ChromatrapÂŽ uses a solid phase porous polymer functionalised with protein A, allowing the chromatin capture to be more efficient than bead based methods. The Chromatrap spin column approach offers significant advantages compared to methods based on sepharose or magnetic beads, which involve many steps of separation, pipetting and re-suspension. Independent tests with Chromatrap demonstrate levels of DNA pull down up to 25 times higher than with traditional bead based procedures, excellent DNA enrichment with signal-to-noise ratios typically 2 to 3 times better than competing procedures...

 

  Untreated Microplates for Growing Cells in Suspension

Porvair Sciences has announced a new range of 12-, 24-, 48- and 96 well format untreated polystyrene culture microplates for growing cells in stationary suspension or other applications where reduced cell attachment is desired

untreated polystyrene culture microplatesUntreated polystyrene plates are the lab tool of choice for growing embryoid bodies and other cells where cell attachment needs to be reduced or avoided. Natural, unmodified polystyrene surfaces are hydrophobic and only bind cells and biomolecules through passive hydrophobic interactions. Moulded from ultra-pure polystyrene in a class 100,000 cleanroom production environment - Porvair untreated culture plates are supplied with lids in individual sterile packs. The proprietary design of Porvair untreated culture plates includes raised well rims to reduce evaporation, a single position lid to avoid cross contamination and alphanumeric code marking to enable easy identification of individual wells...

 

  Meet the Microplate Specialists at Pittcon 2013

Porvair Sciences has chosen the forthcoming Pittcon 2013 exhibition to showcase its latest applications focused microplates and microplate equipment to scientists visiting the event in Philadelphia

the UltraVap MistralVisitors to Pittcon Booth 2854 will be able to meet Porvair's technical specialists, see the company's new MiniSeal II heat sealer, a wide selection of high quality microplates and have a preview of a new microplate evaporator - the UltraVap Mistral. The new MiniSeal II from Porvair Sciences offers users unmatched reproducibility in sealing microplates of all types and sizes. Operating with a very high force ensures the MiniSeal II delivers high integrity sealing of deep well or even irregularly shaped microplate...

 

  Parallel Sample Preparation System for HPLC Vials

Porvair Sciences has announced a new version of its MiniVap™ Blowdown Evaporator able to quickly and safely remove solvent from up to 48 vials in parallel

 the new MiniVap Vial HolderMade from solvent resistant black polypropylene the new MiniVap Vial Holder has been designed to accommodate up to 48 vials* in a standard SLAS / ANSI format. Incorporating advanced evaporator head technology which directly injects heated nitrogen into 48 HPLC vials simultaneously, the MiniVap removes the traditional laboratory ‘bottleneck’ of solvent evaporation from vials...

 

  Bringing Microplate Innovation to Market

For organizations looking to commercialise technology innovations or companies looking to develop a high quality product with a competitive edge - Porvair Sciences has a long history of successfully helping customers develop new and innovative microplates and microplate equipment

Porvair Sciences has a long history of successfully helping customers develop new and innovative microplate

Specialising in microplate technology since 1992 - Porvair Sciences has accumulated a wealth of technical and production expertise that have made its custom microplate design and manufacture service second to none. Academic research groups and commercial companies are able to benefit from a range of proprietary techniques used by Porvair in the generation of custom microplates including polymer ultrasonic welding, plasma surface treatment, co-sintering of polymers / silicas and 'two-shot' injection moulding...

 

  Effortless Access to Microplate Information

Porvair Sciences, specialist manufacturer of high quality microplates, microplate equipment and tissue culture plastics, has launched a new website to provide visitors with in-depth information relating to its comprehensive range of products and custom design service

New Porvair Sciences websiteDesigned to enable visitors to effortlessly navigate through over 900 products, arranged according to application use, the new website is truly a site worth bookmarking by microplate and tissue culture plastics users. Reflecting the global nature of Porvair's business the new site has been developed in English, Chinese, French and German...

 

  Protecting Light Sensitive Samples from Degradation

To protect light sensitive samples - Porvair Sciences offers a selection of high quality, black microplates and seals that eliminate sample degradation, even over long storage periods

black microplates and sealsManufactured from ultra-pure grade polypropylene, Porvair black microplates are resistant to a wide range of solvents and have near zero leachates ensuring long-term sample integrity. The black plates are supplied RNase / DNase free meaning they can be used with even the most sensitive biological samples. Available in a choice of 96-well formats - Porvair black plates are precisely manufactured to applicable ANSI / SLAS dimensions* ensuring complete compatibility with almost all readers and automated equipment...

 

  High Throughput Sample Clean-up

The Microlute™ SPE sample preparation system from Porvair Sciences provides a faster, trouble-free alternative to cartridges for high throughput sample clean-up

The Microlute™ SPE sample preparation systemHandling samples as small as 150ul the Microlute™ SPE sample preparation system helps you increase your assay sensitivity by providing pre-injection clean-up and concentration you can trust. As a complete package, including filter plate, collection plate, waste tray and manifold, the Microlute™ SPE sample preparation system offers all the advantages of automated and high throughput SPE sample preparation in a convenient microplate format capable of rapidly processing 96 samples in one go repeatedly and precisely...

 

  Economic Approach to Protein Precipitation Sample Preparation

The Combipack™ is Porvair Sciences economic response to the growing use of protein precipitation separation techniques in chromatography labs

Porviar combipackComprising four Porvair p3 protein precipitation plates and four 1ml deep well collection plates (colour coded in red or blue polypropylene) the Combipack provides all the elements you require to undertake protein precipitation separations at a very affordable price...

 

  Economic Approach to Protein Precipitation Sample Preparation The CombipackTM is Porvair Sciences economic response to the growing use of protein precipitation separation techniques in chromatography labs.

Porviar combipackComprising four Porvair p3 protein precipitation plates and four 1ml deep well collection plates (colour coded in red or blue polypropylene) the Combipack provides all the elements you require to undertake protein precipitation separations at a very affordable price...

 

  Multi-Well Plates Ensure High Filtered Sample Integrity The need for reliable methods to purify samples and improve assays has led Porvair Sciences to develop a range of proprietary multi-well filtration microplates optimised for applications including cell harvesting, DNA separations, binding studies, plasmid isolation, general filtration and sample clean-up.

porvairpr35Filtration plates are used in their simplest form to remove particulate matter from liquid, typically either the particulate matter or the filtrate is needed for further study. Included within the Porvair range are filtration plates that can simultaneously filter 96 or 384 samples of up to 350Âľl volume providing great productivity benefits and high filtered sample integrity. For larger volume applications (up to 5 ml / well) a choice of 48-well filtration plates are available...

 

  Sterile Glass Bottom Assay Plates Sterile Glass Bottom Assay PlatesPrecision engineered KrystalTM glass bottom plates from Porvair Sciences are manufactured using a polystyrene upper and a borosilicate glass sheet fixed to the base with a biocompatible adhesive.  This proprietary process results in consistent flatness (+/- 15 microns) across the base, excellent light transmission and a flat optical plane for growing cells...

 

  New Serological Pipettes and Pipette Controllers Brochure Porvair Sciences has issued a new brochure detailing its range of serological pipettes and pipette controllers that form part of its increasing presence in the tissue culture plastic consumables market.

Porvair serological pipettesPorvair serological pipettes are high-quality disposable pipettes that can be used for a variety of applications. The range of disposable, colour-coded, Porvair pipettes covers all the popular sizes from 1ml to 50ml and includes special shortened "mini" pipettes for use in safety cabinets and confined spaces. Made the highest quality virgin crystal polystyrene, Porvair pipettes have graduations calibrated for accurate dispensing to within Âą2%...

 

  Sample Preparation Products for Regenerative Medicine Porvair tissue culture plastics Porvair Sciences has chosen the forthcoming Achema 2012 exhibition in Frankfurt am Main, Germany (18th - 22nd June 2012) to show its latest sample preparation products for epigenetics and regenerative medicine. Visitors to Achema Stand F44 in Halle 4.2 will be able to see Porvair's growing range of tissue culture plastics which, while affordably priced, are made to the highest international standards for material quality, surface finish, tissue culture treatment, sterility and pack integrity...

 

  Automation Friendly Microplate Products Universal Robotic ManifoldPorvair Sciences will present its complete range of automation friendly microplates and equipment at European Lab Automation 2012 in Hamburg, Germany in partnership with long-term collaborator, KBiosystems. Visitors to the Porvair / KBio stand at ELA 2012 will be able to see the Universal Robotic Manifold plus a growing range of high quality reagent reservoirs. The Universal Robotic Manifold is designed to be easily assembled and disassembled by robotic manipulators, thus enabling productive automation of SPE or DNA clean-up procedures...

 

  Porvair introduces New Flip Cap Centrifuge Tubes Porvair 15ml and 50ml flip cap centrifuge tubesPorvair Sciences has introduced a new range of high grade polypropylene flip cap centrifuge tubes that combine ease of use, chemical resistance and high speed tolerance. Designed for easy one-handed operation the secure leak proof flip cap lid on each centrifuge tube can also be unscrewed. Available in a range of standard sizes the dimensions of Porvair flip cap centrifuge tubes are compatible with almost all centrifuge rotors. Affordably priced - Porvair flip cap centrifuge tubes can be spun up to 9400G and will withstand repeated autoclaving at 121C or long term storage at -80C. For easy identification each centrifuge tube has a solvent resistant writing area...

 

  Gas Permeable Adhesive Seals for Live Cell Assays Porvair Sciences 500120 series gas permeable adhesive microplate seals.Porvair Sciences announces the introduction of the 500120 series gas permeable adhesive microplate seals. These unique gas permeable adhesive seals allow uniform air and carbon dioxide (CO2) exchange, but prevent moisture evaporation making them perfect for Eukaryotic cell culture and long-term live cell assays...

 

  Heat Sealer reproducibly seals microplates of all types & size The new MiniSeal Plus heat sealer from Porvair SciencesThe new MiniSeal Plus heat sealer from Porvair Sciences operates with a very high force thereby ensuring high integrity sealing of deep well or even irregularly shaped microplates. Building upon the proven track record of Porvair's trusted MiniSeal semi-automatic microplate sealer - MiniSeal Plus offers users even greater comfort and safety in use, together with unmatched reproducibility in sealing microplates of all types and sizes...

 

  Optimised PCR plates for all thermal cyclers and sequencers Porvair Sciences range of high quality PCR platesManufactured from polypropylene for extra rigidity the Porvair Sciences range of high quality PCR plates are compatible with the majority of 96- and 384-well block PCR and sequencing instruments, including FAST sequencers. Summarised in an easy-to-use selection guide - the Porvair PCR plate range of standard or low profile 96-well PCR plates are available in specific optimised formats (full, half or no skirt), with well volumes of 100-200 microlitres...

 

  Porvair Sciences Announces 2012 Microplate Catalogue Porvair Sciences Catalogue Many scientists around the world have come to rely upon the Porvair Sciences Catalogue as a primary source of information that enables them to choose the optimum microplate or tissue culture consumable for their application. The new 2012 edition brings together information on Porvair Sciences comprehensive microplate and microplate instruments product range, together with a recently introduced range of high quality epigenetics and tissue culture plastics. Reflecting Porvair's continuing commitment to continuous technological innovation, the 2012 catalogue introduces a suite of exciting new products...

 

  Low Profile Deep Well Plate Increases Storage Capacity low profile deep well microplatePorvair Sciences has introduced a low profile deep well microplate designed to make optimum use of storage space in HPLC autosamplers, robotic stackers and freezers. The new low profile 96-well deep well plate achieves a storage volume of 1.6ml / well in a height of just 32 mm.  This allows more plates to be stored or stacked in a give space.  Combining an affordable price with uncompromising high quality, Porvair low profile 1.6ml deep well plates are precisely manufactured to comply with ANSI/SBS dimensions** ensuring complete compatibility with all automated sample handling systems, microplate readers and washers...

 

  High quality flasks streamline cell culture workflow Porvair cell culture flasksPorvair Sciences has announced a new range of affordable, high quality cell culture flasks with design features to streamline your cell culture workflow. Combining the unrivalled optical purity of high-pressure molded 100% USP Class VI virgin crystal polystyrene with a patented low-pressure gas plasma surface treatment allows cells to adhere more efficiently to the surface by reducing its hydrophobicity. Highly polished moulds and rigorous quality control ensure that you get perfect visualization every time...

 

  New Cell Culture Dishes for all Applications Porvair cell culture dishes Porvair Sciences has introduced a new line of cell culture dishes that support a range of applications and growth of many important cell types including primary cells, stem cells, neuronal, mesenchymal, hepatocyte, and endothelial cells. Available in a range of sizes and styles - Porvair cell culture dishes are designed for optimal performance and ease-of-use.  Porvair cell culture dishes include lids designed for optimal gas exchange and stacking rings that facilitate easy stacking and handling...

 

  Affordable, High Quality Cell Culture Flasks Porvair cell culture flasks Porvair Sciences has announced a new range of affordable, high quality cell culture flasks with design features to streamline your cell culture workflow. Combining the unrivalled optical purity of high-pressure molded 100% USP Class VI virgin crystal polystyrene with a patented low-pressure gas plasma surface treatment allows cells to adhere more efficiently to the surface by reducing its hydrophobicity. Highly polished moulds and rigorous quality control ensure that you get perfect visualization every time...

 

  Independent Report Compares Tissue Culture Plastics Porvair tissue culture products An independent evaluation by the University of Swansea, UK was undertaken to investigate characteristics of established cell lines in culture using tissue culture vessels from Porvair Sciences and comparing this to using products from another leading manufacturer. The researchers conclude that the Porvair tissue culture products provide a viable and economic alternative to the market leading supplier...

 

  Entry Level Electronic Microplate Sealer Porvair MiniSeal microplate sealer Porvair Sciences reports that its entry level MiniSeal microplate sealer is proving popular with laboratories handling smaller batches of plates and in particular those tasked with sealing deep well plates that require extra pressure. Designed for convenience the compact MiniSeal just requires plugging into a single electrical outlet to operate. The need to site your thermal sealer near a compressed air source or buying a dedicated compressor is eliminated...

 

  Zero Crosstalk Luminescence Assay Plate Krystal 2000 plate from Porvair Sciences LtdConstructed in ultra-pure grade polystyrene, the opaque white Krystal 2000 plate from Porvair Sciences Ltd. maximises reflectivity enabling even weakly emitting luminescence assays to be routinely undertaken. Designed for luminescence applications that require the highest levels of photometric accuracy and repeatability the Krystal 2000 white microplate (well volume - 350 microlitres) incorporates a unique clear cup design that eliminates the performance-limiting well-to-well light crosstalk inherent in most other clear bottomed microplate designs...

 

  High Quality Tissue Culture Plasticware 'High Quality Tissue Culture Plasticware' from Porvair SciencesDrawing upon its many years experience of supplying scientists with tissue culture treated microplates - Porvair Sciences have announced a new range of range of carefully selected and quality controlled tissue culture treated laboratory plasticware...

 

  Low Volume Bioassay SPE Preparation and Clean-ups BioVyon™ C18 silica microplates from Porvair Sciences BioVyonTM C18 silica microplates from Porvair Sciences Ltd offer unmatched performance in low volume Bioassay Solid Phase Extraction (SPE) sample preparation and clean-ups. Traditional packed bed SPE microplates perform relatively inefficiently when using the shallow sorbent beds necessary to get good recovery from smaller sample volumes. By immobilising the C18 sorbent within the porous BioVyonTM polymer - Porvair have created a novel, high surface area, low bed volume matrix that provides unmatched control of flow rate...

 

  Glass Bottom Microplates for Imaging Applications Krystal™ glass bottom plates from Porvair Sciences Precision manufactured to be extremely flat (+/- 15 microns across base) - KrystalTM glass bottom plates from Porvair Sciences provide unmatched performance for whole-plate CCD imaging and laser detection applications. Available in a choice of 24-, 96- and 384-well formats - Krystal glass bottom plates combine the advantageous optical properties of glass, low background and low birefringence, with the versatility of a microplate...

 

  Productive SPE Sample Preparation MaxiLute™ solid phase extraction (SPE) system from Porvair Sciences The MaxiLuteTM solid phase extraction (SPE) system from Porvair Sciences is fully compatible with automated liquid handling and robotic devices providing considerable productivity benefits. The MaxiLute is a novel 48-well SPE microplate system that offers significant advantages for laboratories currently using SPE cartridges...

 

  Wide Range of Microplate Reservoir Trays Microplate Reservoir Trays Porvair Sciences offers a wide range of disposable Reservoir trays designed for use with any robotic liquid handling system. Reservoirs are available offering options to accommodate a single liquid or partitioned space for several liquids. Most working configurations are accounted for as well as liquid volumes...

 

  High yield cell growth microplates BactiGrowth plates from Porvair SciencesBactiGrowth plates from Porvair Sciences provide an optimal microplate solution enabling high yield growth of bacteria, yeast, mammalian or insect cell lines. Every batch of BactiGrowth plates is rigorously tested to validate their contamination-free status ensuring reproducibility and maintaining customer confidence in the cells you grow. BactiGrowth plates are available in a choice of well formats (24-, 96- and 384-well) and well volumes from 300 Âľl to 10 ml per well to suit most cellular growth applications...

 

  Free Microplate-shaped USB Memory Stick Porvair Microplate USB SticksWe know that your laboratory works with microplates - but how do you save the data you generate from them? Porvair Sciences Ltd. is offering free-of-charge, for a limited time, attractive microplate-shaped 1GB USB memory sticks just for this purpose. Tell us the main application your lab uses microplates for and the memory stick is yours!

 

  Optimised Filter Plates Porvair Sciences Porvair Sciences has developed a range of high performance filter plates to suit most filtration applications. Filter plates are used in their simplest form to remove particulate matter from liquid where either the particulate matter or the filtrate is required for further study...

 

  UV Clear Bottomed Microplates Porvair UV Clear Bottomed MicroplatesAvailable from Porvair Sciences Ltd - the Krystal UV range of high specification, quartz-bottomed microplates are designed for scientists using assay chemistries which require excitation or detection in the far UV spectral region...

 

  Personal Evaporator for HPLC Sample Preparation MiniVap™ Blowdown Evaporator from Porvair Sciences The MiniVap Blowdown Evaporator from Porvair Sciences takes just minutes to remove volatile organic solvents from your HPLC fractions collected in 24- or 96-well microplates. Compact in design the affordably priced MiniVap is simple to install, operate and maintain. Installation just requires connection to a gas supply and standard mains socket. Safety of operation is ensured as the CE marked compact unit fits into all fume cupboards...

 

  High Quality 96-well Deep Well Plates Porvair 96-well Deep Well PlatesA wide range of high quality 96-well deep well plates are available from Porvair Sciences Ltd. optimized for applications in cell biology, molecular biology, drug discovery, combinatorial chemistry, screening and genomics...

 

  Versatile Filter Plate Vacuum Manifold Versatile Filter Plate Vacuum ManifoldThe Universal Robotic Manifold from Porvair Sciences has been designed to operate with all brands of filter plate and waste collection reservoir tray. Adaptable to work with three different lengths of drip director (short, medium and long) the Universal Robotic Manifold is able to accommodate collection plates from 14mm - 44mm in height...

 

  Win a luxury chocolate microplate Win a luxury chocolate microplatePorvair Sciences Ltd. is offering all laboratories that register the main applications they use microplates for - a special thank-you by sending them a delicious full-size chocolate microplate made from the finest Belgian chocolate together with a digital or printed copy of their latest 2010-2011 Microplates & Microplate Equipment catalogue

 

  Microplate Chemical Compatibility Reference Guide Microplate Chemical Compatibility Reference GuidePorvair Sciences has announced a reference guide for scientists that details the chemical compatibility of materials used in microplates to a wide range of common laboratory chemicals. Downloadable direct from the Porvair Sciences website the easy-to-use reference guide describes the compatibility of different microplate matrices and membranes to a wide range of acids, alcohols, bases, esters, hydrocarbons, chlorinated hydrocarbons, ketones and other chemicals.

 

  Biomedical Researcher wins Microplate Catalogue prize draw Dr Ian McFarlaneA scientist at the Genomics CoreLab of the NIHR Biomedical Research Centre at Addenbrooke's Hospital (Cambridge, UK) has won Porvair Sciences' latest free prize draw for people registering online for the company's 2010-2011 Microplate Catalogue.

 

  Streamlining the Protein Precipitation Sample Preparation Technique The p3 microplate from Porvair Sciences LtdThe p3 microplate from Porvair Sciences Ltd. eliminates the mess and complex sample preparation (no centrifuging, no vortexing) traditionally associated with protein precipitation techniques.

 

  SPE Methods Development Made Easy Microlute™ Solid Phase Extraction (SPE) microplate Porvair Sciences has introduced a version of its popular MicroluteTM Solid Phase Extraction (SPE) microplate which provides a wide assortment of phase chemistries and sorbent loadings in a single plate making it ideally suited for method development. The mix of phase chemistries and sorbent loadings available in the Development MicroluteTM allows you to simply and rapidly screen for the optimal retention and selectivity required to achieve your sample preparation objectives.

 

  Porvair Sciences Announces International Sales Growth Porvair Sciences Announces International Sales GrowthPorvair Sciences Ltd, an established specialist manufacturer of microplates and microplate products, has reported 9% growth in international sales for the fiscal year ending November 30th 2010.

 

  Oligo Manufacturer Standardizes On Ultravap for Sample Preparation Ultravap™ Blowdown Station Porvair Sciences Ltd. has announced that a leading manufacturer of ready-made oligonucleotides, with bases in both North America and Europe, has standardized on their UltravapTM Blowdown Station for careful drying of their production samples.

 

  New Manual Thermal Plate Sealer from Porvair Sciences MicroSeal - a new budget priced manual microplate heat sealer Porvair Sciences has announced the MicroSeal - a new budget priced manual microplate heat sealer that offers great performance. Designed to meet the needs of low to medium throughput laboratories for microplate sealing the MicroSeal is compact and easy-to-use. An ergonomic pull down mechanism makes single action heat sealing of a wide range of plates quick and simple.

 

  Porvair Announces Low Profile 96-well Microplate Porvair Announces Low Profile 96-well Microplate Porvair Sciences Ltd, specialists in applications optimised microplates, has announced a low profile 96-well microplate designed to minimise the space required for compound storage.

 

  High Volume Plate Optimised for High Yield Yeast Production High Volume Plate Optimised for High Yield Yeast ProductionA 24-well microplate, with a working volume of 10ml / well, has been developed by Porvair Sciences Ltd. for large scale, high yield growth of yeast. Produced under class 10,000 clean room conditions from virgin polypropylene, the new 24-well plate contains no contaminants that may leach out and affect yeast growth

 

  Eliminating the Difficulties In Handling Adhesive Sealing Films Porvair Sciences has announced MicroBurst - a revolutionary new microencapsulated clear sealing film for microplates.

 

  Robot-Compatible Blowdown Evaporator Porvair Sciences' Ultravap Microplate Evaporator has become a trusted standard for removing unwanted solvents from laboratory microplates. The open-access design of the Ultravap, combined with full RS232 control of every parameter, enables integration with laboratory robotics

 

  Low and High Binding Filtration Plates Drawing upon a selection of proprietary microfilters - Porvair Sciences has developed a comprehensive range of low and high binding plates with well volumes ranging from 350Âľl to 5ml to suit almost all filtration applications.

 

  Porvair Sciences Announces Q3 2010 Events Program Porvair Sciences Ltd has announced a comprehensive program of events it will attend over the next few months to launch its 2010 / 2011 Microplate Catalogue and introduce several new products.

 

  Glass Vial Storage Microplates Porvair Sciences has announced a new introduction to its range of storage microplates. For scenarios where chemical resistance and thermal stability is vital - the new Glass Vial Storage Plate offers 96 high quality glass vials in a 45mm high storage block - ideal for UHPLC and combinatorial chemistry applications.

 

  Porvair Sciences Announce 2010/2011 Microplate Catalogue Many scientists around the world have come to rely upon previous editions of the Microplate Catalogue from Porvair Sciences Ltd. as a primary source of information that enables them to choose the right assay, filter, storage or PCR plate.

 

  Win a digital SLR camera ! Porvair Sciences Ltd. is offering laboratories that register to receive its new 2010-2011 Catalogue of Microplates & Microplate Equipment the chance to win a brand new Canon EOS1000D DSLR camera

 

  High Integrity Compound Storage Plate Manufactured from ultra-pure grade polypropylene under clean room conditions the 2ml square deep well microplate from Porvair Sciences Ltd. is the 96-well plate of choice for laboratories tasked with high integrity compound storage, fraction collection and SPE collection..

 

  Heat Seals for PCR, Storage & Life Science Applications Porvair Sciences, specialists in microplate technology, has announced a new range of aluminium heat seals for PCR, storage and life science applications.

 

  Acrylic Manifold for Vacuum Separations Available from Porvair Sciences Ltd. the Acrylic Manifold has been designed to be fully compatible with all ANSI / SBS standard* compliant solid phase extraction, filtration, protein precipitation and collection plates.

 

  Maintaining the Integrity of Light Sensitive Samples Porvair Sciences has announced a black microplate and seal combination that eliminates sample degradation by exposure to light, even over long-term storage periods.

 

  Rapid Microplate Solvent Removal Incorporating advanced evaporator head technology and an innovative manifold design, which directly injects heated nitrogen into each well of a 96-well microplate simultaneously, the affordable MiniVapTM from Porvair Sciences takes just minutes to remove volatile organic solvents from your plate.

 

  Video Presentation Brings Microplate Sealer 'To Life' Porvair Sciences Ltd. has announced the launch of a new video presentation for its popular MiniSeal Plus microplate sealer.

 

  Online Video Presentations Bring Microplate Products 'To Life' Porvair Sciences Ltd. has announced the launch of a new suite of product presentation videos for its website. Located at www.porvair-sciences.com/videos.php the new product presentation video facility has been designed to offer a new level of useful information to anyone involved with using microplates or microplate technologies.

 

  Report On Extractables Testing In Deep Well Microplates A new technical report is available from Porvair Sciences Ltd. that investigates and demonstrates the importance of high quality raw material selection for the manufacture of deep well microplates.

 

  New Comprehensive Microplate Catalogue The Porvair Sciences Product Catalogue for 2010 is packed with vital information on the company's wide range of microplates, plate sealers and microplate evaporators to help you get the best from your separations, assays and storage applications.

 

  Reliable Easy-to-Use Microplate Sealer Porvair Sciences has announced that a new pdf download brochure is now available for its MiniSeal Plus thermal microplate sealer.

 

  Informative Report on Deep Well Microplate Sample A new technical report is available from Porvair Sciences Ltd. that investigates and demonstrates the importance of high quality raw material selection for the manufacture of deep well microplates.

 

  Reproducible High Integrity Plate Sealing The Thermobond II manual heat sealer from Porvair Sciences Ltd. has been designed to seal polypropylene collection plates, PCR plates, microplates and deep well blocks with a specially prepared pierceable film or foil. Sealing plates prevents sample evaporation and leakage during storage and transportation

 

  Sterile Shallow Well Plate Porvair Sciences Ltd. has announced a new sterile 96-well Shallow Polypropylene Plate that offers a capacity of just 150ÂľL per well reducing reagent costs and round well bottoms to ensure good mixing.

 

  Increased German Market Focus for Porvair Sciences Porvair Sciences Ltd has chosen the forthcoming Analytica meeting in Munich, Germany (23rd - 26th March) as the launch pad for its increased focus on German speaking markets in 2010

 

  Partitioned Reagent Reservoir Helps Save Deck Space Porvair Sciences Ltd. has announced a new 4-row partitioned reservoir plate that enables aspiration of up to 4 reagents into a single well space thereby saving valuable deck space on your automated liquid handling system.

 

  Affordable, high quality 2ml compound storage plate The 2ml square deep well microplate from Porvair Sciences Ltd. is the 96-well plate of choice for laboratories involved with compound storage.

 

  OEM Microplate Design & Production Specialists in microplate technology - Porvair Sciences Ltd. has announced a 20% growth in its OEM design and manufacture business during 2009

 

  Continuous Roll Microplate Heat Sealer The TriSeal Pro from Porvair Sciences Ltd. is a new budget-priced continuous roll microplate heat sealer optimised for medium to high throughput plate sealing applications

 

  High Volume Microplate for Sensitive Photometric Assays With a well volume of 3.1ml the Krystal 24 from Porvair Science Ltd. is the microplate of choice for screening applications that require high sensitivity combined with photometric accuracy and repeatability. In addition the Krystal 24's large surface area per well makes the tissue culture treated version of the plate perfect for cell growth applications.

 

  Technical report compares well-to-well crosstalk in luminescence microplates Porvair Sciences Ltd. has announced a new technical report that evaluates well-to-well crosstalk in commercially available microplates used for luminescence measurements.

 

  Microplate Sealer Combines Ease-of-Use & Excellent Repeatability. Porvair Sciences has announced a new budget priced, semi-automatic thermal microplate sealer - the MiniSeal Plus.