Channels

 

Special Offers & Promotions

 

 

Latest News

 

 

View Channel

New Products

 

 

View Channel

Video Presentations

 

 

View Channel

Separation Science

 

 

View Channel

Microscopy & Image Analysis

 

 

View Channel

Laboratory Automation & IT Solutions

 

 

View Channel

 

Krystal Microplate Enables Development of Drug Testing Assay for Plasmodium vivax

publication date: Sep 22, 2017
 | 
author/source: Porvair Sciences Limited

Porvair Sciences reports that the National Center for Biological Sciences (NCBS) in Bangalore, India is using its Krystal 384 black microplate to produce a standard drug testing assay for Plasmodium vivax infection.

Krystal Microplate The NCBS (https://indiabioscience.org/orgs/ncbs) is a leading national institute whose faculty members undertake research in the frontier areas of biology. Scientists at the NCBS use experimental and computational approaches to study molecules, cells and organisms creating an understanding of the biology at each of these levels to advance an integrated view of life processes.

In their research, the NCBS is using Krystal 384-well black microplates as the microenvironment to grow the cells infected with small numbers of parasites. Researchers are then treating the Krystal 384 black plates with different concentrations of drugs to check the effect on the infection and the development of the Plasmodium vivax parasites inside the cells.

Dr Mulaka Maruthi, a senior NCBS researcher commented "Because they are manufactured to a very high flatness tolerance the Porvair Sciences Krystal 384-well black plates are very convenient to use with both our inverted microscope and High Content Screening machine. The clear plate bottom permits direct microscopic viewing or HCS imaging and the images are of high resolution". Dr Maruthi added "Using the Krystal 384-well black plates we have been able to minimize the number of cells for seeding, use smaller numbers of parasites, and lower volumes of drugs. Overall the Krystal 384 black plate has enabled us to perform these experiments in a single plate instead of many 96 well plates or other well formats".

The Krystal 384-well microplate range incorporates novel square wells with a large liquid capacity of 120µl per well, increasing the achievable sensitivity of most HTS assays. Using a proprietary manufacturing technique, the Krystal 384 offers market leading plate flatness (+/- 0.1mm tolerance) that translates into a significant increase in measurement precision and elimination of read errors when performing cell based assays using fluorescent or luminescent imaging. All tissue-culture treated plates are supplied lidded and sterile, in individual bags.


more about porvair sciences


more news from porvair sciences


 


If you have not logged into the website then please enter your details below.



 

Subscribe to any of our newsletters for the latest on new laboratory products, industry news, case studies and much more!

Newsletters from Lab Bulletin

 

Request your free copies HERE

 

 

 

Popular this Month

Top 10 most popular articles this month

 

 

Today's Picks

 


 

Looking for a Supplier?

Search by company or by product

 


Company Name:

Product:


 

 

 

 

Please note Lab Bulletin does not sell, supply any of the products featured on this website. If you have an enquiry, please use the contact form below the article or company profile and we will send your request to the supplier so that they can contact you directly.

Lab Bulletin is published by newleaf marketing communications ltd.


 

Media Partners

 

Exhibitions & Events