To enable pharmaceutical researchers to move quickly into their high‑throughput screening experiments, global genomics solutions provider Integrated DNA Technologies (IDT) has released rapid genes, a new offering in its synthetic biology portfolio. Available from 125 base pairs (bp) to 2000 bp, IDT’s rapid genes are ready-to-use, next generation sequencing (NGS)-verified clonal genes shipped in as little as five business days...

Life sciences companies Integrated DNA Technologies (IDT) and Element Biosciences, Inc. have bolstered their partnership with products to enable more efficient and streamlined next generation sequencing (NGS) workflows for users of the AVITI System, an innovative sequencing and multi-omics platform based on Element’s novel avidity base chemistry. Launching today is a suite of high-quality adapters, universal blockers and library amplification primer mixes designed exclusively for the AVITI System..

With a mission to accelerate the pace of genomics, Integrated DNA Technologies (IDT), a leading provider of differentiated next generation sequencing (NGS) solutions, announces the availability of xGen NGS products designed exclusively for the Ultima Genomics UG 100™ platform. The suite of new xGen NGS tools comprised of adapters, primers, and universal blockers can support a wide range of applications, including DNA, RNA and methylation sequencing workflows, as well as IDT’s proven hybridization capture chemistry..

New ready-to-ship xGen™ NGS solution will enable researchers to combat challenging diseases of today and prepare for the next pathogen of tomorrow. To meet customer demand for a multiplexed, multiple respiratory disease target panel that provides comprehensive genome coverage, Integrated DNA Technologies (IDT) is revealing a new next generation sequencing (NGS) solution, the xGen Respiratory Virus Amplicon Panel...

Integrated DNA Technologies, Inc. (IDT) has announced it closed on the purchase of Next Generation Sequencing (NGS) research assays from Invitae Corporation under the trademarked name Archer®. The integration of IDT’s portfolio with the acquired NGS research assays—which have been foundational in researching novel cancer fusions—will empower labs with an all-in-one solution to uncover biomarkers and advance cancer discoveries...

To support the growing need for an inhibitor resistant, high-performance master mix that allows for direct amplification of crude samples, Integrated DNA Technologies has launched the PrimeTime™ 1-Step 4X Broad-Range qPCR Master Mix. The unique, proprietary blend in this master mix is ideal for viral research and other gene expression applications and features a 4X concentrated formulation that eliminates the need for an extraction step...

Continuing its mission to advance biological research worldwide, Integrated DNA Technologies (IDT) has launched oPools™ Oligo Pools – ready-to-use pools of high quality DNA oligonucleotides (oligos) up to 350 nucleotides in length. Thanks to its industry-leading proprietary oligo manufacturing processes and 30 years of dedication to exceptional quality products, IDT is able to provide oligo pools unparalleled in uniformity at yields that accelerate experiments by eliminating....

As part of its ongoing mission to break down the barriers in genomics research, Integrated DNA Technologies (IDT) is extending its network of collaborations into food quality and safety. Through a new multi-year supplier agreement, IDT will be the primary supplier of NGS oligo products for Clear Labs’ groundbreaking automated and intelligent NGS-based food safety platform....

As part of its commitment to advocate for the genomics age, Integrated DNA Technologies (IDT) aims to lower the barriers to access the latest NGS technologies. In line with this mission, the company has launched a preferred sequencing provider program with McDonnell Genome Institute (MGI) at Washington University....

Integrated DNA Technologies (IDT) announces that it has entered into a strategic cooperation with ChosenMed Technology (Beijing) Co., Ltd (ChosenMed), a medical sequencing firm focused on personalized medicine and transformation healthcare in China. As part of the collaboration, IDT will provide its market-leading NGS enrichment products* for cancer sequencing to ChosenMed, and also help to enhance its scientific research...

New high-performance, cost-effective PACE SNP assays will lower the cost and improve the reliability of SNP or indel screening. In the latest collaboration in a series to advocate for genomics research, Integrated DNA Technologies (IDT) is teaming up with 3CR Bioscience (3CR) to widen access to quality custom solutions for genotyping screening. The partnership fuses IDT’s industry-leading oligo synthesis with...

As an advocate for the needs of researchers working at the forefronts of genomic research, Integrated DNA Technologies (IDT)releases its latest CRISPR enzyme Alt-R® Cas12a (Cpf1) Ultra. Cas12a Ultra is a powerful addition to IDT’s Alt-R CRISPR enzyme arsenal – its vastly improved performance makes it easier to achieve precision genome editing at new sites across genomes...

Demonstrating its advocacy for genomics research, Integrated DNA Technologies (IDT) announces a significant expansion to its NGS portfolio. The company is excited to launch a unique Custom NGS Adapters offering, becoming the only genomics provider to provide an easy and flexible customized adapter solution directly to scientists. The cornerstone of this new offering is a truly innovative web-based configurator tool....

Product is the result of a partnership with Integrated DNA Technologies, and provides clinical-stage clients with a critical raw material. Aldevron, a leading contract development and manufacturing organization serving the biotech industry, announces the release of GMP SpyFi Cas9 Nuclease for clinical and commercial applications. SpyFi Cas9 Nuclease, the trade name for Aldevron’s research grade and GMP products....

Increasing accuracy and reducing cost barriers, IDT’s innovative system delivers simple and cost-effective amplicon sequencing. As a dedicated innovator of tools and solutions for genomics applications,Integrated DNA Technologies (IDT)introduces its unique,rhAmpSeq™targeted sequencing system - providing researchers with highly accurate, cost-effective and easy-to-use amplicon sequencing on Illumina®next-generation sequencing (NGS) platforms...

As an advocate for researchers in the genomics age, Integrated DNA Technologies (IDT)is expanding its courier zones to ensure that the highest-fidelity oligos are available in less time and at the same price, to more customers. UK scientists based in Cambridge, Oxford, and London—both inside and out of the M25 orbital—can now benefit from IDT’s free next-day delivery service, enabling projects to be started and finished sooner....

Demonstrating its commitment to advocating for synthetic biology research, Integrated DNA Technologies’ (IDT) Synthetic Biology Start-up Grant Program has once again benefited innovative start-ups in their missions to impact sustainable manufacturing, human health, and/or humanitarian causes. The program provides much-needed synthetic biology products designed to support the next generation of companies aiming to impact these important areas using synthetic biology...

IDT wins two prestigious Life Science Industry Awards. In recognition of its dedication to advocating for customers,Integrated DNA Technologies (IDT), has won a prestigious Life Science Industry Award for Best Overall Customer Experience, as well as a Gold award for Most Useful Website. The awards—entirely nominated and voted for by scientists—validate IDT’s continued efforts to support scientists at every stage of...

Research published in Nature Medicine describes collaborative effort to reduce off-target CRISPR-Cas9 genome editing – removing barriers for human therapeutic applications. Genome editing using the CRISPR-Cas9 system has tremendous promise for therapeutic correction of genetic errors in human cells. Prior to adoption as a medical therapeutic, safety concerns relating to off-target effects must be minimized to...

New website increases accessibility to leading-edge product range and latest information. As advocates for the genomics age, Integrated DNA Technologies (IDT), has launched a new version of its website designed to enhance support to researchers across the globe. The updated website features easy-to-find product information arranged by application and fast navigation - saving valuable time and...

New application note gives researchers insights and guidance on maximizing HDR-mediated insertion of short fragments in CRISPR genome editing

As an advocate for the genomics age, Integrated DNA Technologies (IDT), has published a new application note on optimization of CRISPR-Cas9 for homology-directed repair (HDR) applications. Available as part of the IDT collection of CRISPR application notes and protocols, this article supports researchers using CRISPR...

Support and recognition for biodiversity research with potential for global impact

Demonstrating its ongoing commitment to science advocacy and sustainability, Integrated DNA Technologies (IDT), is inviting applications for its 2017 Sustainability Award program. Open to researchers working on biodiversity projects in academic, non-profit, and government labs, this year IDT has extended the program to...

Integrated DNA Technologies (IDT) today announced the launch of the first Cas9 enzyme variant that extensively reduces off-target effects in CRISPR genome editing without compromising on-target activity.

The Alt-R^® S.p. HiFi Cas9 Nuclease 3NLS enzyme is a recombinant S. pyogenes Cas9 mutant that improves specificity while maintaining a high editing efficiency similar to wild-type Cas9. The launch represents a major step towards therapeutic use of CRISPR, which has previously borne the risk of the unwanted off-target editing events observed with wild-type Cas9....

Innovative method delivers simple, accurate and cost-effective SNP analysis

Reflecting its mission to provide innovative solutions to the genomics community, Integrated DNA Technologies (IDT) introduces its unique rhAmp™ SNP Genotyping System, enabling researchers to make accurate and confident SNP calls both quickly and cost-effectively....

Leaders in NGS tools collaborate to deliver robust multiplexing capabilities and streamline target enrichment methods

Integrated DNA Technologies (IDT) have announced a broad partnership with Illumina, Inc. to provide improved library preparation multiplexing and target enrichment solutions for the next generation sequencing (NGS) market....

Researchers in Switzerland no longer need to import IDT products; local expertise facilitates ordering

Integrated DNA Technologies (IDT), has signed a distributor agreement with LubioScience GmbH (LubioScience), based in Lucerne, Switzerland. Through LubioScience, researchers in Switzerland will benefit from local access to IDT’s full range of high quality reagents for genomics research...

IDT expands its capacity for direct sales of genomic products in Asia-Pacific region

Integrated DNA Technologies (IDT), through its Singapore subsidiary, today completed the acquisition of the oligonucleotide manufacturing business of GeneWorks Pty Ltd. (GeneWorks) in Australia. This acquisition sees IDT expand its reach in the Asia-Pacific region, following its recent establishment of sales offices in Japan and Korea.....

Expanded CRISPR toolkit includes Cpf1 and range of Alt-R™ support products, increasing the options available to molecular biology researchers

Reflecting its drive to provide innovative solutions to the genomics community, Integrated DNA Technologies (IDT) is the first genomics company to develop and bring to market a complete ribonucleoprotein-based Cpf1 CRISPR system. The Alt-R™ A.s. Cpf1 CRISPR System inherits the optimized, efficient, and cost-effective traits of IDT’s innovative Cas9-based system while taking advantage of Cpf1’s natural AT-rich target sequence preference....

Integrated DNA Technologies (IDT), the world leader in custom oligonucleotide synthesis, announces the winners of its 2016 Sustainability Award contest.

This award recognizes innovative research that has the potential to make a global impact in the area of biodiversity. This year’s winning projects highlight the importance of sustaining biodiversity in groundwater, seed banks, and the microbiome of birds....

Innovative product development exemplifies commitment to sustainability—reduces waste and saves costs

Integrated DNA Technologies, has developed a unique master mix for probe-based qPCR assays that is stable for ambient shipping. The company’s PrimeTime® Gene Expression Master Mix is the only widely distributed commercial master mix shipped in solution at ambient temperature. Under these conditions, the master mix, which is compatible with a wide range of real-time PCR instruments....

Natural method also is proving effective against dengue and chikungunya

Integrated DNA Technologies, is donating reagents to Eliminate Dengue Brazil to help combat the spread of Zika virus (ZIKV) in Brazil. The Eliminate Dengue Program is an international, non-profit research collaboration led by Prof Scott O’Neill of Monash University, Australia....

Company welcomes new customers with promise to provide seamless support for genomics research

Integrated DNA Technologies, the global leader in custom nucleic acid synthesis, has announced the acquisition of ValueGene, Inc. (“ValueGene”), an oligonucleotide synthesis services company based in San Diego, California. ValueGene offers custom DNA and RNA oligonucleotide synthesis products, including PAGE and HPLC purification and modification services. Dr Joseph A Walder, IDT founder and chief executive officer...

Company now selling directly to customers in South Korea

Integrated DNA Technologies , the global leader in custom nucleic acid synthesis, has acquired MBiotech, Inc. (“MBiotech”), headquartered in Seoul, South Korea. MBiotech has been a distributor of IDT products for more than a decade. In its promotion of IDT products, MBiotech has successfully made IDT’s brand well-known throughout the South Korean peninsula....

Life science companies combine expertise to enhance transcriptome research 

Takara Bio USA, Inc. (TBUSA, formerly Clontech Laboratories, Inc.), a wholly owned subsidiary of Takara Bio Inc., and Integrated DNA Technologies (IDT) today announced a new collaboration to support targeted RNA sequencing. This relationship will leverage IDT’s unrivalled proficiency in the manufacture and quality control of long oligonucleotides and TBUSA’s expertise in developing low-input solutions for...

Integrated DNA Technologies (IDT), the global leader in nucleic acid synthesis, announces its 2016 Platinum Level sponsorship of the International Genetically Engineered Machine (iGEM) competition.

The iGEM Foundation conducts a yearly international competition for students interested in synthetic biology. Last year, more than 280 teams from 39 countries participated in the competition. IDT also will provide each registered team with up to 20KB of its market leading gBlocks® Gene Fragments synthetic DNA products—for a total value of almost US$1M. “We are very proud to continue our support of iGEM teams that enable...

Caribou has granted IDT worldwide rights to commercialize CRISPR-Cas9 reagents under Caribou™s intellectual property.

The license is subject to a research use limited label. "We are proud to partner with Integrated DNA Technologies, a prominent leader in the field of nucleic acid based technologies",

Sophia Genetics announces a strategic partnership with Integrated DNA Technologies to accelerate the adoption of next generation sequencing (NGS) in routine clinical diagnostics.

PrimeTime^® qPCR Assays and Master Mix from IDT provide superior efficiencies and reliability for gene expression studies

Integrated DNA Technologies (IDT) has introduced its latest addition to an expanding genomic applications portfolio: PrimeTime^® Gene Expression Master Mix, an optimized enzyme mix for probe-based qPCR. IDT continues to provide higher value qPCR products by delivering superior assay performance at a lower price per reaction, while empowering customers with access to assay sequences. This newest product enhances the...

IDT enables insightful NGS results in clinical and companion diagnostics research, every time

Integrated DNA Technologies (IDT), introduces its new xGen^® Exome Research Panel v1.0 for insightful analysis of the human exome via next generation sequencing. A total of 429,826 probes span 39 Mb of the human genome, providing deep and uniform coverage of 19,396 genes. This leads scientists directly to relevant mutations, aiding advances in clinical and companion diagnostics research. By using the xGen Exome Research Panel with xGen...

Biodiversity research on methane sinks and global warming earns $14,001 in oligo credit

Integrated DNA Technologies (IDT), the world leader in custom oligonucleotide synthesis, awarded the inaugural IDT ISO 14001 Sustainability Award to Dr Patricia Tavormina of the Division of Geological and Planetary Sciences at the California Institute of Technology. Dr Tavormina's research focuses on naturally occurring methane-oxidizing bacteria, (MOB), and the role they play in limiting greenhouse gases, which contribute to global warming. IDT introduced...

New IDT Webinar: ‘High throughput qPCR: tips for analysis across multiple plates’

Integrated DNA Technologies (IDT) will be hosting a webinar to help researchers get the most out of gene expression studies that analyze large numbers of samples. Entitled ‘High throughput qPCR: tips for analysis across multiple plates’, the webinar will be presented by Dr Mikael Kubista, founder and CEO of the TATAA Biocenter and head of the Department of Gene Expression at the Institute of Biotechnology of the Czech Academy of Sciences. The webinar will be...

IDT’s Ebola PrimeTime^® qPCR Assay Validated

In a recent DECODED research profile, Integrated DNA Technologies (IDT), details how IDT scientists Kristin Beltz and Dr Scott Rose are collaborating with Dr Brian Taylor’s research team at Battelle (Aberdeen, MD, USA) to design and validate a RT-qPCR assay that can detect the Ebola virus in the field. The IDT PrimeTime^® Ebola qPCR Assay detects Zaire ebolavirus, the species involved in the 2013–2015 West African Ebola outbreak. Initial sensitivity...

IDT first to offer easy online ordering of MGB Eclipse^® qPCR probes licensed for human in vitro diagnostics use

Integrated DNA Technologies (IDT), has become the only company to add fully licensed Minor Groove Binder (MGB) Eclipse^® GMP probes to its online service, enabling quick and efficient ordering. GMP-produced and supplied under license for use as components in human in vitro diagnostic tests, these robust and economical qPCR probes join the company’s wider product portfolio of GMP probes and primers available to order through the...

IDT facilitates a unique, scalable method for analyzing hundreds of enhancer:promoter interactions in a single assay

Advancing the development of novel methods for understanding gene expression, Integrated DNA Technologies (IDT) has enabled Dr Jim Hughes, Associate Professor at the Weatherall Institute of Molecular Medicine, Oxford, UK, to optimize his unique Capture-C method, based on Chromosomal Conformational Capture (3C). As outlined in the recent DECODED Online article, Understanding How Distal Regulatory Elements Control Gene...

Dr Caifu Chen to lead new product development at California site

Already the world’s leader in custom nucleic acid synthesis, Integrated DNA Technologies (IDT) is capitalizing on its expertise to deliver a broader range of validated molecular biology products. Research and development for these products will now be performed in a newly built facility in Redwood City, California. The 8,000 square foot building houses state-of-the-art labs that will allow IDT scientists to maximize the company’s world-class...

In a recent DECODED Online entry, Integrated DNA Technologies (IDT), the world leader in oligonucleotide synthesis, provides an overview of the CRISPR/Cas9 system to scientists looking to enhance their genome modification strategy in model organisms or cell lines.

The CRISPR/Cas9 system has rapidly become a leading method for genome editing. Faster and more efficient than other methods, the system is continually being improved. This entry informs researchers on the latest developments and highlight the potential of this evolving technology. Bringing together the latest information on CRISPR/Cas9, the piece links through to resources that cover the many advantages over other methods such as...

IDT supports bioengineering educational initiative that will provide color-changing flowers

To help the general public understand how bioengineering is changing the world for the better, Integrated DNA Technologies (IDT) is supporting a unique public outreach program led by expert plant synthetic biologists at Revolution Bioengineering. Detailed in a recent DECODED article, “Color-Changing Flowers—Biotechnology for Everyone”, Revolution Biotechnology is creating bioengineered Petunia flowers that change color on...

Comprehensive resource pools the latest in the field for newcomers and experts

Integrated DNA Technologies (IDT) has pooled its expertise in genome editing into a free web resource dedicated to providing researchers a hub of information on the very latest in using the CRISPR/Cas9 system. On the webpage, researchers can find a range of educational and practical resources suited to those both experienced and new to genome editing. These include a recent highly successful and comprehensive IDT webinar...

To accelerate the understanding of disease and the development of gene knockdown therapies, Integrated DNA Technologies (IDT) is facilitating the advancement of a new transfection technique.

This nanoparticle-based method is explored in a recent DECODED article contributed by Precision NanoSystems Inc. (PNI). By combining IDT’s highly potent Dicer-substrate RNAs (DsiRNAs) and PNI’s unique nanoparticle delivery system for hard-to-transfect cells, the IDT-PNI partnership presents a successful solution for challenging gene silencing applications, achieving >95% transfection efficiency. The novel NanoAssemblr™ system and...

Integrated DNA Technologies (IDT), and Ubiquitome today announced a partnership to develop the Ubiquitome Freedom4 Real-Time RT-PCR Ebola Virus Assay for easy use in the field.

This rapid test is designed to be run on Ubiquitome’s hand-held, battery powered real-time PCR device, the Freedom4. IDT, a market leader in the manufacture of GMP quality products for use in molecular diagnostic tests, is leveraging its PrimeTime qPCR Assay platform to develop an assay that will provide accurate and consistent test results for Ebola virus disease. Fitting in the palm of a hand, Ubiquitome’s Freedom4...

Integrated DNA Technologies (IDT) has acquired a license from ELITech Group (Bothell, WA) to manufacture and supply MGB Eclipse^® Probes for use as a component in human in vitro diagnostic tests.

As a result of improved knowledge and understanding of the human genome, quantitative real-time PCR (qPCR) has become an increasingly important tool for in vitro diagnostics and patient management. The gold standard 5′ nuclease qPCR assay uses oligonucleotide probes that have three critical features: fluorescent reporter dyes, quenchers for these dyes, and a minor groove binder. qPCR is a sensitive method for detecting abnorma...

In a recent DECODED Online article,  scientists at Geneseeq Technology, Inc., a cancer diagnostics company, demonstrate improved target capture methods for increasing reliability of next generation sequencing data, particularly important for clinical diagnostics.

The scientists’ insights cover use of blocking oligos, optimizing hybridization conditions, and getting the most out of formalin-fixed and paraffin embedded (FFPE) samples. Geneseeq provides clinicians with guided treatment solutions for cancer, based on comprehensive, systematic analysis of patients’ genomic mutations. The company was an early adopter of IDT’s xGen^® Lockdown^® Probes and uses these with xGen^® Blocking Oligos to...

Integrated DNA Technologies (IDT), the world leader in oligonucleotide synthesis, today announced the introduction of xGen^® Predesigned Gene Capture Pools and Plates.

These modular gene capture probes are the latest addition to IDT’s growing portfolio of high quality, customizable next generation sequencing products. xGen Predesigned Gene Capture Pools and Plates are ideal for creating customized target capture panels for enrichment of 10 or more genes or for enhancing the performance of existing panels. Predesigned Gene Capture Pools and Plates are ideal for scientists who need to reduce the cost of...

In DECODED Online, Integrated DNA Technologies (IDT), the world leader in oligonucleotide synthesis, looks at how its novel RNase H2–dependent polymerase chain reaction (rhPCR) method has helped researchers to detect differential amplification of alternatively spliced latrophilin (Lphn) transcripts in mice.

Latrophilins are cell adhesion molecules that have been linked with synaptic function, development, and maintenance. The three Lphn genes are very similar, which complicates the use of standard qRT-PCR to distinguish the various transcripts. The rhPCR method developed by IDT overcomes this problem by simultaneously increasing PCR specificity and eliminating primer-dimer formation. This is achieved by using blocked primers, which require cleavage by...

Integrated DNA Technologies (IDT), the world leader in oligonucleotide synthesis, is sharing its wealth of qPCR expertise and knowledge in a special qPCR compendium edition of the DECODED newsletter, available free of charge online.

In this issue, number 4.2, researchers can read an interview with internationally recognized expert on quantitative PCR, Dr Jo Vandesompele. Discussing the common issues researchers face when using qPCR, and the future direction of the technology, Dr Vandesompele notes a trend towards digital PCR (dPCR). For those who want to discover dPCR in more depth there is a special article dedicated to the topic – ‘Digital PCR (dPCR) – what is it and...

Two new xGen® next generation sequencing panels to be launched

Integrated DNA Technologies (IDT), the world leader in oligonucleotide synthesis, is extending its portfolio of NGS panels with the addition of the xGen^® Inherited Disease and Pan-Cancer Panels. Adding these to the xGen AML Panel which was launched at the end of last year, IDT now offers a range of panels for deep sequencing that can be supplemented to cover a comprehensive range of diseases....

Integrated DNA Technologies (IDT) announced today a minority investment by growth equity investor Summit Partners. IDT’s founder, Dr. Joseph Walder, will remain the company’s majority owner. Additional terms of the investment were not disclosed.

IDT is the world’s largest manufacturer of custom nucleic acid products. The company supplies scientists with synthetic DNA and RNA sequences, serving the academic research, biotechnology, clinical diagnostics, and pharmaceutical sectors. IDT develops innovative products while providing unmatched product value, excellent delivery times, and personalized customer service....

Sequence and application flexibility allow for the exploration of CRISPR and Cas9 function

Integrated DNA Technologies (IDT), the world leader in oligonucleotide synthesis, advances CRISPR research with the use of its gBlocks Gene Fragments. Detailed online in the latest issue of DECODED, CRISPRs can be used in conjunction with CRISPR associated (Cas) proteins, for example Cas9 has been well documented, to recognize and cleave complementary DNA. This mechanism, which is found naturally within bacteria and archaea to protect cells from foreign sequence, has been harnessed for use in genome editing.

IDT presents latest developments at AGBT

Integrated DNA Technologies (IDT), the world leader in oligonucleotide synthesis, will present its findings on the use of molecular inversion probes (MIPs) for next generation sequencing (NGS) target enrichment at the 15^th annual Advances in Genome Biology and Technology (AGBT) meeting in Marco Island, Florida, Feb 12-15. John Havens PhD, Vice-President of Business Development at IDT, will talk about MIPs and their proven effectiveness in the enrichment of genomic content of biological samples for specific regions of interest...

Integrated DNA Technologies Presents at Antibody Engineering and Therapeutics 

Michel Cannieux, PhD, MBA, Director of Product Commercialization, Synthetic Biology at IDT discussed a novel, rapid and reliable method to build and clone genes of interest at a fraction of the cost of full gene synthesis. The talk, entitled “Rapid and Reliable Gene Construction with gBlocks™ Gene Fragments and Gibson Assembly™ Method” took place at 12.00 on December 11. As double stranded, sequence verified DNA blocks up to 750 base pairs, gBlocks Gene Fragments have high sequence fidelity. As a result, they are ideal for use in a broad range of biological applications....

Harvard professor explains how to programme complex oligo structures for new applications 

The quarterly newsletter DECODED, from Integrated DNA Technologies (IDT) explores the work of Dr Pen Yin, assistant professor of systems biology at Harvard Medical School, who is harnessing the base pairing properties of DNA to create 3D structures of “DNA bricks”. This new nano-construction technique is based on short DNA oligos, which assemble at right-angles to interlocking sequences, forming 3D units. With such a heavy dependency on oligonucleotide quality, Dr Yin has relied on IDT. These DNA bricks are inspiring many future applications, such as catalysts and drug compounds, and can eventually be used to create electrical circuit boards on the nanometer scale...

Enhancing the performance of target capture experiments

Integrated DNA Technologies (IDT), the world leader in oligonucleotide synthesis, has launched the latest addition to its portfolio of next generation sequencing (NGS) products, xGen® Universal Blocking Oligos. By incorporating these oligos into target capture experiments, users can decrease the complexity and increase throughput of their target capture experiment without degradation of performance. Blocking oligos are commonly used to enhance the performance of capture experiments, through the prevention of cross-hybridization between adapter sequences...

Fast and accurate screening for mutations identified in acute myeloid lymphoma using the xGen® Acute Myeloid Lymphoma Panel v1.0

Integrated DNA Technologies (IDT), the world leader in oligonucleotide synthesis, is enabling cancer research with its latest next generation sequencing (NGS) product, the xGen® Acute Myeloid Leukemia Cancer Panel v1.0. Consisting of 11,743 xGen Lockdown® Probes, this cancer panel targets over 260 clinically relevant genes that were found to be mutated in a study of 200 patients with acute myeloid leukemia (AML), and published by The Cancer Genome Atlas consortium. The AML Cancer Panel is used for enriching the genome for regions of interest before performing NGS. It can, therefore, be used to study disease occurrence and progression, and help with the development of better targeted therapies...

IDT xGEN^® Lockdown^® Probes advance research at the University of Texas at Austin, USA

Integrated DNA Technologies (IDT), the world leader in oligonucleotide synthesis, provides researchers in Prof Jeffrey Barrick’s laboratory (University of Texas at Austin, USA) with its xGEN^® Lockdown^® Probes for target enrichment of specific gene regions. Detailed in the DECODED quarterly newsletter from IDT, Prof Barrick’s research team is developing methods to track rare mutations in evolving populations to assess effects on fitness from sequence alone...

The perfect choice for qPCR, on any scale

Integrated DNA Technologies (IDT), the world leader in oligonucleotide synthesis, has further expanded its portfolio of PrimeTime^® qPCR products with the launch of two new probes. The PrimeTime Eco Probe and PrimeTime Mini LNA Probe complete the existing offering, providing new options for customers performing gene expression and genotyping experiments...

IDT helps users to safeguard their experiments

Integrated DNA Technologies (IDT), the world leader in oligonucleotide synthesis, provides an overview in the latest issue of its quarterly newsletter, DECODED, of the importance of checking for single nucleotide polymorphisms (SNPs) when designing PCR assays. If PCR is performed using primers that overlap a SNP, the SNP can impact the progress of the PCR, and thus the accuracy of resulting data...

The IDT newsletter DECODED features the latest research to rescue the CFTR functionality

Integrated DNA Technologies (IDT), the world leader in oligonucleotide synthesis, offers insight into recent research that has unearthed an miRNA-regulated network implicated in the pathogenesis of Cystic Fibrosis (CF). Described in the April edition of DECODED, the international IDT customer newsletter, optimized DIG-labeled DsiRNAs (IDT) were used to develop a novel, enhanced approach for oligonucleotide delivery....

World’s largest supplier of custom nucleic acids opens SGD 6 million manufacturing facility in Singapore

Already the world’s leader in custom nucleic acid synthesis, Integrated DNA Technologies (IDT) has expanded its manufacturing capabilities to Singapore. IDT is now able to provide locally-manufactured oligonucleotides to researchers in Singapore and throughout the region from the company’s first synthesis facility in Asia. In January of 2012, IDT acquired the oligo business of Singapore’s top supplier, 1st BASE Pte. Ltd. Shortly thereafter, IDT began work to create a state-of-the art hub for oligo manufacturing and support dedicated to the Asian market. IDT completed the nearly SGD 6 million project in spring of 2013, and the Singapore company’s synthesis and other processes are now fully integrated with IDT’s operations in the US and Europe...

PrimeTime® qPCR Assay Plates with online tool for ordering primers and probes in 96 well format

Integrated DNA Technologies (IDT), the world leader in oligonucleotide synthesis, has announced the launch of PrimeTime^® qPCR Assay Plates, for high throughput qPCR analysis. Primers and probes for 5’-nuclease and intercalating dye assays (e.g., SYBR^®) can now be directly ordered online in a 96 well plate format, eliminating the time-consuming transfer of primers and probes from reagent stocks, and streamlining the reaction set-up. PrimeTime qPCR Assay Plates offer an ideal solution for many applications that generate large quantities of data, such as validation of NGS and microarray data, as well as high throughput gene expression screening...

Integrated DNA Technologies, Inc. (IDT) and SGI-DNA announce an expanded partnership to develop, manufacture, and market a variety of synthetic DNA products

IDT is the world’s leader in custom oligonucleotide synthesis and SGI-DNA is a newly formed subsidiary of Synthetic Genomics, Inc. (SGI), which focuses on genomic-driven solutions to a variety of global needs. In February of 2012, IDT and SGI began to co-manufacture, commercialize, and market small synthetic gene products of up to 5 kb....

Providing fast and accurate gene assembly