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Advanced Materials Technology are pleased to announce HALO® Fused-Core® Selectivity Toolkits – containing 3 columns and available for a limited time – to help bring develop HPLC methods with the speed and efficiencies of UHPLC methods! Available with pore sizes of 90 Å for small molecule analysis and 1,000 Å for biomolecule analysis, each column in the toolkit can be screened under the same mobile phase conditions to help you develop your ultra-fast separation quickly and efficiently.....
Hichrom now owns the worldwide exclusive rights to manufacture the Alltima®, Alltima® HP, Prevail™, Apollo™, Allsep®, Apex™, and Genesis™ HPLC column ranges from Grace. Additionally, Vydac® HPLC columns continue to be available exclusively from Hichrom. Hichrom manufactures these column ranges to the same exacting manufacturing protocols and to identical technical specifications previously used by Grace/Alltech in manufacturing facilities accredited to both ISO9001 and ISO14001 standards...
Do you want improve your chromatography or have requirements when it comes to your training? If so, you could benefit from training courses by Hichrom! Our courses – delivered by world renowned experts including Mel Euerby and Mark Power – are designed to cater to every level of experience, from chromatography newcomers to more seasoned professionals....
In May 2016, Hichrom acquired the worldwide exclusive rights to manufacture the Alltima®, Alltima® HP, Prevail™, Apollo™, Allsep®, Apex™, and Genesis™ HPLC column ranges from Grace. Additionally, Vydac® HPLC columns are now available exclusively from Hichrom. Hichrom manufactures these column ranges to the same exacting manufacturing protocols and to identical technical specifications previously used by Grace/Alltech in manufacturing facilities accredited to both ISO9001 and ISO14001 standards....
Advanced Material Technologies (AMT) have announced the brand-new HALO® 1,000 Å ES-C18 phase as part of their BioClass range of Fused-Core® HPLC columns! This unique phase is perfect for the separation of monoclonal antibodies, antibody-drug conjugates, and large proteins....
Hichrom’s 2018 training courses
HALO 160 Å Peptide Phenyl-Hexyl – a BioClass Fused-Core HPLC/UHPLC column – is specifically designed to offer alternative selectivity to C18 and CN columns, for separations of peptides and tryptic digests. It offers excellent separation of peptide and protein digests, unique selectivity, rugged stability and excellent lot-to-lot reproducibility.
This unique phase is based on TYPE-C™ silica in which the silica surface is populated with silicon-hydride bonds instead of silanols. Patented bonding technology is used to create the ‘Diamond-Hydride’ with direct silicon-carbon bonds on the silica hydride surface....
Trastuzumab (MW ~148 kDa) is used to treat breast cancer. Enhanced resolution of trastuzumab and its variants is acheived using a new HALO 1000Å C4 column. HALO 1000Å C4 columns contain the world’s first 2.7 micron superficially porous silica particles with 1000Å pores....
New HALO 1000Å C4 columns contain the world’s first 2.7 micron superficially porous silica particles with 1000 Angstrom pores. The pore size and structure of these particles enable molecules to achieve complete penetration of the porous structure, allowing them to interact with more of the bonded surface for better retention and selectivity....
John Dolan, Mel Euerby and other leading experts deliver world class chromatography training in 2017
Jan 23, 2017
Whether you are a relative newcomer to chromatography or a seasoned veteran, you can benefit from one of our courses. New courses for 2017 include Pharmaceutical Data Integrity, Preparative HPLC and Method Development for HILIC Separations.Costs for our courses are just £55 for a short course and from £195 for a day course and ChromSoc, RSC and IBMS members all receive a 10% discount on all courses....
Metabolomics and bioanalytical laboratories worldwide have widely recognized the benefits of using Cogent TYPE-C HPLC columns for their HPLC separations. The new Cogent columns catalogue is now available. This 48-page technically-focused catalogue includes a description of the features and benefits of TYPE-C Silica phases, which are based on silicon-hydride surface chemistry and are ideal for the separation of polar compounds...
Vydac, Alltima, Alltima HP, Prevail, Apollo, Allsep, Apex and Genesis HPLC Columns are Still Available
Jun 27, 2016
Hichrom is pleased to announce that we have acquired the worldwide exclusive rights to manufacture and sell these analytical HPLC column ranges from Grace. All columns are manufactured to identical protocols and to the same exacting specifications previously used by Grace/Alltech. Part numbers also remain unaffected by this acquisition. Based in the UK, Hichrom is a leading European manufacturer and distributor of UHPLC and HPLC columns, consumables and media, with manufacturing facilities accredited to both ISO9001 (Quality) and ISO14001 (Environmental) standards.
Solve your Sample Management Control Problems with New U-2D 96 Well Plates from MicroSolv
Apr 25, 2016
The key benefits of the U-2D 96 Well Plates system include:
Training from John Dolan, Mel Euerby and other leading chromatography experts - Hichrom
Feb 22, 2016
These HALO-2 Peptide columns are packed with 2 µm “core-shell” type particles having an optimised pore size of 160 Å. This provides greater separation efficiencies for these types of biomolecules.
The novel design enables the rack containing precision glass inserts to be removed from the plastic base, for checking individual inserts for bubbles or missed fills, or for transfer to a thermal bath for controlled heating or cooling. Additionally individual glass inserts can be removed and placed into 9mm screw top autosampler vials for storage or for transfer to another instrument platform. This enables small volume samples to be stored with minimal loss of sample.
The novel design enables the rack containing precision glass inserts to be removed from the plastic base, for checking individual inserts for bubbles or missed fills, or for transfer to a thermal bath for controlled heating or cooling. Additionally individual glass inserts can be removed and placed into 9mm screw top autosampler vials for storage or for transfer to another instrument platform. This enables small volume samples to be stored with minimal loss of sample.
Researchers today are keenly interested in both fast and high resolution separations of numerous biomolecules to support the development of novel therapeutic proteins and peptides in pharmaceutical drug development, to advance understanding in modern university laboratories, to characterise protein post-translational modifications and to fully assess subtle differences in biosimilars and other products of bioengineering and manufacture.
Princeton Chromatography were the first company to develop and market the popular 2-Ethylpyridine phase which was launched in 2001 and later the 4-Ethylpyridine phase. PrincetonSFC 2-Ethylpyridine has become the column of choice for achiral SFC analysis of basic compounds. This phase generally requires no addition of amines to the eluent, producing excellent peak shape and reproducibility.
The new HALO Glycan HPLC stationary phase is a high performance material specifically targeted for separations of highly polar oligosaccharides, and particularly protein-linked glycans and glycopeptides, by hydrophilic interactive liquid chromatography (HILIC). The phase has a highly polar ligand containing 5 hydroxyl groups, which is attached to a 2.7micron Fused-Core silica particle via novel proprietary linkage chemistry....
Cogent Diol is a 4um diol bonded phase suitable for the reversed-phase or aqueous normal-phase (ANP) analysis of polar compounds and is LC-MS compatible. Columns show fast equilibration between gradient runs and can be successfully used in studies of pathways in human pathology.
Cogent TYPE-C silica HPLC phases offer unique opportunities for the separation of a wide range of sometimes difficult to separate compounds. They have the ability to retain polar solutes at high concentrations of organic solvent by aqueous normal-phase (ANP) and non-polar compounds under reversed-phase (RP) conditions.
Whether you are a relative newcomer to chromatography or a seasoned veteran, you can benefit from one of our courses. In addition to the well-established and well received theoretical courses (which are available as full day training courses or short 1-2 hour seminars), a wide range of practical ‘Hands-On’ courses covering all aspects of LC, LC/MS, GC, GC/MS and sample preparation is now also available.
The patented CDMR vial manufacturing process and design results in an internal glass surface that is virtually seamless, eliminating the “internal ridge” that may result in some vial designs when the vial blank is fused to the vial bottom. This “internal ridge” can retain up to 17ul of fluid sample in a 1.8ml vial....
These adsorption properties are routinely tested by MicroSolv using LCMS and other analytical techniques, by measuring the degree of disappearance of polar compounds from solution over time due to ionic interactions with the glass surface. MicroSolv have demonstrated that ordinary (non-RSA glass) vials adsorb far greater levels of these basic, polar compounds....
Kromasil EternityXT UHPLC/HPLC Columns
These columns use patented bonding technology to create a surface populated by silicon-hydride functional groups instead of silanols. The lack of surface silanols leads to fast equilibration times, excellent peak shape and extended column lifetimes for a wide range of analytes. To demonstrate the unique abilities of Cogent TYPE-C silica LC phases a wide range of application notes are available including.....
Type-C silica columns have a surface populated by silicon-hydride functional groups instead of silanols. These bonded phases have the ability to retain polar solutes at high concentrations of organic solvent by aqueous normal-phase (ANP) and non-polar compounds under reversed-phase conditions. The lack of surface silanols leads to fast equilibration times, excellent peak shape and extended column lifetimes...
In addition to HPLC, UHPLC and superficially porous particle columns, the latest catalogue contains details of SFC, GC, SPE, TLC, Flash, CE, LC-MS and GC-MS products. Vials, syringe filters, tubing, fittings and other chromatography accessories are also included. This catalogue includes a comprehensive and invaluable technical summary section with a wide range of LC and LC related topics, plus detailed overviews on C1 to C30 columns and Polar Embedded, Wide Pore, HIC, Phenyl, PFP, Polar Bonded, HILIC, Silica, Ion-Exchange, SEC, Affinity and Chiral phases, all with helpful column recommendations.
In addition to the full programme of 1 and 2 day courses, a comprehensive series of short 1¾ hour seminars is also available, either as open enrolment courses or for on-site training. New courses for 2014 include: Superficially Porous Phases – Development and Benefits, The Analysis of Polar Molecules, Method Development Strategies to Exploit Selectivity in UHPLC/HPLC and The Technique of Gas Chromatography - in 3 parts.
One of the most common causes of LC column failure is particulate material collecting on the inlet frit of the column, causing high back pressure and/or distortion of peak shape. By one estimate, over 70% of LC column failures are caused by inlet frit plugging. UHPLC columns, especially those packed with sub-2μm size particles, are particularly vulnerable to inlet frit plugging. Advanced Chromatography Technologies offers three different ranges of pre-column filters, each designed for column specific protection...
Bridge the Gap between HPLC and UHPLC with HALO Fused-Core columns - time is running out
Oct 25, 2013
RStech Corporation of Korea manufactures the OPTIMAPAK and HECTOR ranges of HPLC columns and the INOPAK range of SPE columns. OPTIMAPAK columns are available in C18, C8, NH2 and Silica chemistries. The newer HECTOR HPLC column ranges include series of bonded phases, offering the customer a wide choice of selectivities. The INOPAK SPE range consists of C18, C8, NH2, Silica and Florisil phases for high recoveries and a wide range of applications...
Contained within the catalogue is information on over 100 LC column brands and details of products from over 35 chromatography suppliers. In addition to HPLC, UHPLC and superficially porous particle columns, the new catalogue contains details of SFC, GC, SPE, TLC, Flash, CE, LC-MS and GC-MS products. Vials, syringe filters, tubing, fittings and other chromatography accessories are also included.....
RSA Glass vials are not coated or silanized. The lack of surface silanols make RSA Glass vials an excellent choice for many applications. If you are working with sensitive compounds commonly found in natural products, biological samples or chemical synthesis, the glass wall of your vial could be a problem for basic compounds. With RSA Glass vials this problem is eliminated....
HALO-5 columns are initially available in C18 and PFP phases and have been specifically developed in order to provide improved HPLC performance when used with traditional HPLC equipment, as the lower back pressure of these columns is ideally suited to these instruments. It has been demonstrated that for a given operating pressure, HALO-5 columns deliver significantly higher efficiency than a column packed with 5µm totally porous particles...
Detect low abundance analytes normally adsorbed by glass
HALO Penta-HILIC is the latest addition to the original 2.7µm range of Fused-Core columns manufactured by Advanced Materials Technology. HALO columns feature a 0.5µm porous silica layer ‘fused' onto a 1.7µm solid silica particle. The resulting columns provide faster separations and higher sample throughput, without compromising column efficiency, ruggedness and reliability. These Fused-Core particles generate significantly lower back pressure compared to other UHPLC columns, enabling them to be used with conventional HPLC as well as UHPLC equipment.
Partisil and Partisphere HPLC column ranges acquired by Hichrom from Whatman/GE Healthcare
Mar 23, 2012
Hichrom Limited are pleased to announce the acquisition of the Partisil® and Partisphere® HPLC column consumable product line from Whatman, a division of GE Healthcare. Based in the UK, Hichrom are a leading European manufacturer and distributor of HPLC columns, consumables and media, with manufacturing facilities accredited to both ISO9001 (Quality) and ISO14001 (Environmental) standards...
A next generation of glass reduces the interaction of analytes and the glass
Hichrom Limited have launched a new breakfast seminar - "Practical Chiral Chromatography - a User's Perspective." This seminar is being held in Cambridge (27th July), Oxford (28th September), York (26th October) and Manchester (23rd November) and costs just £25...
Hichrom are pleased to announce that YMC-Triart C18, a revolutionary, multi-layered, hybrid material from YMC, is now available in 1.9µm particles. Manufactured using innovative "micro-reactor" technology, YMC-Triart's unique structure firmly tackles the challenges of high pH separations (pH 1-12) and high temperature separations (up to 70oC)...
A new approach for sample adsorption and extraction of volatile and semi-volatile components
May 23, 2011
MonoTrap is a state-of-the-art tool for the extraction and analysis of volatile and semi-volatile components by MMSE (Monolithic Material Sorption Extraction), which will be of interest to many industries including the perfume and cosmetic, food and beverage, forensic, toxicology, environmental, chemical and biochemical...
GC and its uses in the modern analytical laboratory, 28th & 30th June, Reading & Manchester
Apr 21, 2011
Hichrom Limited & Thermo Scientific are running GC Seminars taking place at the Madejski Stadium, Reading on the 28th June and at the Radisson Blu Hotel, Manchester Airport, on the 30th June. These days will be of great interest to all those who are involved in Gas Chromatography in the modern analytical environment and wish to expand their knowledge or simply want to keep up-to-date with the latest developments in GC...
HALO, the ‘original' Fused-Core UHPLC columns manufactured by Advanced Materials Technology, feature a 0.5µm porous silica layer ‘fused' onto a 1.7µm solid silica particle. The resulting columns provide faster separations and higher sample throughput, without compromising column efficiency, ruggedness and reliability. HALO® PFP is the latest addition to the range of original Fused-Core® columns for HPLC and UHPLC (ultra-fast) separations...
Hichrom's 2011 HPLC training programme is now available, featuring courses covering every area of HPLC and delivered by world-renowned experts John Dolan, Mel Euerby and Tom Jupille. Whether you are a relative newcomer to HPLC or a seasoned veteran, you can benefit from one of these courses.
A new approach for sample adsorption and extraction of volatile and non-volatile components.
Sep 30, 2009
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