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New Amicon Pro Purification System for Protein Purification from Merck Millipore

Merck Millipore, the Life Science division of Merck, has introduced Amicon® Pro Purification System for Protein Purification

amicon_pro1This centrifugal device streamlines the affinity purification workflow and minimizes protein loss. Users experience consistent, accurate sample preparation, resulting in more reliable recovery, uncompromised purity and easier data generation.

  • Centrifugal device streamlines the affinity purification workflow and minimizes protein loss
  • Combines the bind, wash, elute, buffer exchange and concentration steps into one device
  • Supports additional applications including depletion of abundant proteins, protein enrichment and clean-up of antibody labeling reactions

 

The Amicon® Pro purification system combines the bind, wash, elute, buffer exchange and concentration steps into one device, eliminating risky sample transfers and reducing hands-on time. The device integrates affinity-based spin column purification with downstream sample concentration and buffer exchange. Featuring a large reservoir that accommodates a range of sample volumes, the Amicon® Pro system reduces the need for multiple washing and elution steps.  

"Traditional protein purification is a long process with many steps, dilutions and multiple tubes, often resulting in protein degradation and loss," notes John Sweeney, Head of the Bioscience business unit, Merck Millipore. "The Amicon® Pro affinity purification system is a game-changing improvement in general affinity purification and also transforms applications such as depletion of abundant proteins, protein enrichment and clean-up of antibody labeling reactions."

In addition to fast and efficient affinity purification, the Amicon® device supports single-spin diafiltration and depletion with concentration in a single step. 

The Amicon® Pro purification system also provides the ideal processing tool for small-batch antibody labeling. Antibody labeling and high-yield purification can be completed in as little as one hour. Antibody cleanup routinely involves the removal of BSA/carrier, labeling, removal of unbound label, dialysis, and final concentration. Using standard dialysis, the procedure can take up to three days to complete. With the all-in-one format of the Amicon® Pro device, loss due to sample transfers is eliminated and recovery can be significantly improved.


more about the The Amicon® Pro purification system


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