Channels

 

Special Offers & Promotions

 

 

Latest News

 

 

View Channel

New Products

 

 

View Channel

Video Presentations

 

 

View Channel

Separation Science

 

 

View Channel

Microscopy & Image Analysis

 

 

View Channel

Laboratory Automation & IT Solutions

 

 

View Channel

 

Merck Millipore Introduces Magna Nuclear RNA-binding Protein Immunoprecipitation (RIP) Kits

publication date: Aug 21, 2014
 | 
author/source: Merck Millipore

Merck Millipore, the Life Science division of Merck, today introduced the Magna™ Nuclear RNA-binding Protein Immunoprecipitation (RIP) kits.

merck logoThese kits are specially designed to allow the discovery and analysis of both coding and non-coding chromatin-associated RNAs. Two versions of the kit are available, enabling users to analyze RNA both strongly and weakly associated with chromatin; one version uses cross-linked chromatin while the other uses native chromatin. Native RIP allows recovery of high affinity, more direct interactions while the cross-linked method is designed to capture higher molecular weight complexes and more readily trap weaker interacting RNAs.

Compared with other kits available to researchers, the Magna™ Nuclear RIP kits deliver much lower background signals, high signal-to-noise ratios and have been demonstrated to work in RNA-seq to enable NGS-based discovery and profiling. The kits offer flexible and scalable input requirements; RNA can be recovered from as few as 5,000 cells (cross-linked) or 100,000 cells (native).  

"A significant amount of research is being invested in understanding the complex nature of how various chromatin-associated RNAs impact gene expression and epigenetic regulation," said Christophe Couturier, Senior Vice President and Head of the Merck Millipore Bioscience Business Area. "With the Magna™ Nuclear RIP kits, researchers now have complete, user-friendly kits to facilitate isolation and identification of regulatory RNAs such as short and long non-coding RNAs, snRNAs and enhancer RNAs."

These new kits add to the family of Magna™ RIP kits first introduced in 2009, which allowed for analysis of cytoplasmic and nuclear-associated RNA molecules. With the new Magna™ Nuclear RIP kits, researchers can target those proteins associated with RNA in a chromatin context.


more about merck millipore


 

 



 

Subscribe to any of our newsletters for the latest on new laboratory products, industry news, case studies and much more!

Newsletters from Lab Bulletin

 

Request your free copies HERE

 

 

 

Popular this Month

Top 10 most popular articles this month

 

 

Today's Picks

 


 

Looking for a Supplier?

Search by company or by product

 


Company Name:

Product:


 

 

 

 

Please note Lab Bulletin does not sell, supply any of the products featured on this website. If you have an enquiry, please use the contact form below the article or company profile and we will send your request to the supplier so that they can contact you directly.

Lab Bulletin is published by newleaf marketing communications ltd.


 

Media Partners

 

Exhibitions & Events