Merck, a leading science and technology company, today announced that the Japan Patent Office and the Intellectual Property Office of Singapore have each allowed the company’s patent application for the use of paired CRISPR nickases, bringing Merck’s number of patents to 22 worldwide. “Paired nickases represent a significant step in increasing specificity through a highly flexible and efficient approach to reduce off target effects in gene editing,” said Udit Batra....

Merck, a leading science and technology company, has announced that it has signed a license agreement providing Evotec SE access to Merck’s foundational CRISPR intellectual property. Evotec, an international biotechnology company headquartered in Hamburg, Germany, will use Merck’s CRISPR genome-editing technology to create edited cell lines for Evotec’s commercial and internal research purposes....

Merck, a leading science and technology company, has announced an RMB 100 million (€ 13 million) seed fund targeted at startups in China. The company also officially opened its innovation hub in Shanghai and announced plans to officially open a second innovation hub in Guangzhou in November. “Our RMB 100 million China seed fund underlines our commitment to invest in the Chinese market,” said Stefan Oschmann, CEO and Chairman of the Executive Board of Merck....

Merck, a leading science and technology company, has announced that the European, Israeli, South Korean and U.K. intellectual property offices have issued formal notices allowing seven additional Merck patent application claims covering CRISPR gene-editing technology, bringing the number of patents to 20 worldwide....

Merck has acquired BSSN Software, a Darmstadt, Germany-based laboratory informatics company that makes data more readily accessible for ease of integration, collaboration, analysis and long-term archiving. “BSSN Software and the capabilities that it brings will allow Merck’s customers to better use and share their scientific data — the most important part of laboratory experiments,” said Jean-Charles Wirth, head of Applied Solutions at the Life Science business sector of Merck...

Merck, a leading science and technology company, and the Broad Institute of MIT and Harvard (Boston, Massachusetts) have announced an agreement to offer non-exclusive licenses to CRISPR intellectual property (IP) under their respective control for use in commercial research and product development....

Three-year cooperation between both companies. Unique approach to quantum chemistry on near-term quantum computers. Merck, a leading science and technology company, today announced a three-year cooperation with Heisenberg Quantum Simulations (HQS), a startup based in Karlsruhe, Germany. The cooperation between the startup and Merck Digital will focus on applying and commercializing software...

Merck and Rigaku Corp. have signed a joint development agreement to develop lab consumables based on highly innovative crystalline sponge technology. Merck and Rigaku are collaborating to develop commercially available lab solutions employing highly innovative crystalline sponge technology. Merck will develop lab consumables to determine the absolute chemical structure of substances on sub-microgram scale.....

Merck, a leading science and technology company, today announced the winners of its Advance Biotech Grant program in North America during its Biotech Start-up Summit at the Cambridge Innovation Center (Massachusetts, U.S.). The grant is given to small- and mid-size biotechnology companies that need funding and expertise to get their therapies to market. “With more than 60 percent of drugs in the pipeline today...

Merck, a leading science and technology company, has announced that it has opened the next round of applications for startup companies to participate in the global Merck Accelerator program. Startups can choose to participate in one of the two programs, either at the company’s Innovation Center at global headquarters in Darmstadt or at its China Innovation Hub in Shanghai.

Merck, a leading science and technology company, announce its participation in a collaboration with the Vaccine Formulation Institute and the European Vaccine Initiative. The effort will provide vaccine process development training courses within TRANSVAC2, a collaborative infrastructure project under Horizon 2020. “Involvement in this project is a natural extension to our longtime focus on accelerating vaccine....

Merck, a leading science and technology company, has announced that Susumu Kitagawa, Professor at the Institute for Integrated Cell–Material Sciences at Kyoto University, Japan, has been named the sixteenth recipient of the Emanuel Merck Lectureship. He is being recognized for his pioneering scientific work in the field of metal organic frameworks (MOFs). His fundamental contributions to the development of this innovative class of nanoporous materials could lead to new ways...

Merck, a leading science and technology company, has announced that it has entered into an agreement with HistoCyte Laboratories Ltd, Tyne, U.K., to be the exclusive multinational distributor of the company’s portfolio of cell line reference products for immunohistochemistry and in situ hybridization....

Merck, a leading science and technology company, has launched the new Stericup^® Quick Release 500 ml vacuum filtration system, a filter bottle system ideally suited for sterile filtration of cell culture media, buffers and reagents.

The Stericup^® Quick Release system is the next generation of the original Stericup^® Sterile Vacuum Filtration System, which has been a staple in labs around the world for decades. The improved liquid sterile filtration system offers ergonomic design updates that optimize user control and...

Merck’s ReadyPlate™ 55 ready-to-use agar plates offer streamlined, convenient and efficient sample testing for quality control of water and filterable beverages.

With a diameter of just 55 mm, ReadyPlate™ 55 plates are much smaller than standard 90 mm plates, freeing up valuable space in the incubator while reducing waste. The plates are available in a variety of certified kits which combine the agar plates with matching membranes needed for testing....

Merck's Advanced Proteomics Grade SOLu-Trypsin is an exclusive, solution stable enzyme for mass spectrometry.

Designed to be stable in solution when refrigerated, SOLu-Trypsin can be used immediately without preparation. Other forms of trypsin require thawing or reconstitution and must be discarded if not used immediately. SOLu-Trypsin allows excess product to be saved for future use, thus eliminating unnecessary waste and cost.....

Merck, a leading science and technology company, has developed a new genome editing tool that makes CRISPR more efficient, flexible and specific, giving researchers more experimental options and faster results that can accelerate drug development and access to new therapies.

This new technique, called "proxy-CRISPR," provides access to previously unreachable areas of the genome. Most natural CRISPR systems, found in bacteria, cannot work in human cells without significant re-engineering....

Merck has announced that BioInvent International AB, a Swedish company which develops novel immuno-regulatory antibodies to treat cancer, is upgrading and expanding its drug manufacturing facility with a full line of Merck’s Mobius^® single-use bioreactors.

BioInvent will add 3-, 50-, 200- and 1000-liter bioreactors to its upstream facility in Lund, Sweden, expanding capacity and improving flexibility and scalability....

Merck, a leading science and technology company, has announced the global launch of the Milli-Q^® IQ 7000 system, the seventh-generation Milli-Q^® water purification innovation.

This launch marks 50 years of providing ultrapure water to scientists in laboratories all over the world. The company announced details about the water purification system during a press briefing at the Pittcon Conference & Expo 2017 in Chicago, Illinois.

Merck's new Integritest® 5 instrument is an easy-to-use, portable and fully automated integrity test system for verification of filters and processing equipment.

The latest model of the first commercially available automated integrity test instrument introduced more than 25 years ago now incorporates an improved algorithm to simplify test creation and accelerate test completion. The user-friendly software makes it easy to set up and manage users and tests, while offering a depth of advanced functionality for those who need additional options....

Merck, a leading science and technology company, today announced the introduction of its new testosterone calibrator kit for in vitro diagnostic (IVD) use.

The certified kit allows users to calibrate assays and verify calibrations, and is the first of its kind to receive CE mark approval, indicating compliance with the European Union's Medical Device Directive. The CE mark allows the kit to be marketed and sold in the European Union and in any country recognizing CE mark approval....

Product offers smaller sample volumes and four times higher throughput than traditional assays

Merck, a leading science and technology company, today launched the MILLIPLEX^® MAP Human High Sensitivity cytokine panelfor faster and more cost-effective human cytokine assays. The new panel allows researchers to achieve four times higher throughput than traditional assays while using smaller sample sizes....

Merck, a leading science and technology company, has announced that it has entered into a set of agreements with Evotec AG, whereby Evotec AG will provide screening services for Merck's collection of genetic reagents such as CRISPR and shRNA libraries.

Merck, a leading science and technology company, has launched the CellASIC® ONIX2 Microfluidic System for advanced live cell imaging.

The system converts laboratory microscopes into powerful tools for live cell imaging to more effectively perform in-depth analysis of cellular mechanisms and behavior in a live environment....

Merck, a leading science and technology company, today announced that its digital acquisition marketing team won the 2016 US Search award for "Best In-House" team.

New EZ-Fit™ Filtration Units from Merck

Merck has expanded its portfolio of EZ-Fit™ filtration units, ready-to-use, disposable filtration devices for bioburden testing. The new EZ-Fit™ filtration units come with a wide range of membrane sizes to suit all applications, and a new patented drain design to accelerate processing of turbid and hard-to-filter matrices....

Elix^® High-Throughput water purification system delivers up to 9000 liters of pure water daily with real-time monitoring 

Purification technologies ensure constant water quality with low and predictable running costs. Merck, a leading science and technology company, have introduced the Elix^® High-Throughput water purification system, providing laboratories with a reliable water purification solution for daily water volumes of up to 9000 liters...

Merck has entered into an agreement with PCAS S.A. to expand Merck’s excipients portfolio. Under the agreement, Merck will be the exclusive, global distributor of the Expansorb^® line of biocompatible and biodegradable polymers.

The portfolio will include 38 polymers for sustained release of small molecule and selected peptide injectables, allowing customers to optimize and precisely control release kinetics of final drug products. The ability to better control and sustain the release of drugs allows for delivery via reduced numbers of injections with the same therapeutic efficacy...

Emprove^® risk assessment program provides easy access to information on materials used for drug product manufacturing

Merck has expanded its industry-leading Emprove^® risk assessment program to include a selection of products for filtration and single-use processing. The program provides documentation and regulatory information on materials used in the manufacture of drug products.....

Program aims to improve access to cancer care in Africa and increase number of oncologists on the continent - Paediatric and adult medical fellowship planned for African doctors in India

Merck, a leading science and technology company, today announced to start the first Merck Africa Medical Oncology Fellowship Program for Sub-Saharan African countries in partnership with University of Nairobi, Kenya. The program will be conducted at University of Nairobi and is part of Merck’s efforts to improve access to cancer care and strengthen the healthcare system in emerging markets....

Merck, a leading science and technology company, is expanding its popular line of Guava® flow cytometers to include a high-power modulated green laser. 

The addition of a 532 nanometer laser expands the detection capabilities of the Guava® easyCyte instrument line to enable simultaneous detection of multiple fluorescent proteins. It also offers researchers more spectral choice using fluorescent reagents. More powerful violet, blue and red lasers are now standard in most configurations, meaning the Guava® cytometers are sensitive enough to detect subcellular particles as small as viruses....

Merck, a leading science and technology company, today introduced the IsoBag™ for faster, easier and more convenient transfer of contact and settle plates to production isolators. 

The new IsoBag™ offers a more streamlined alternative for environmental monitoring, and helps make workflows more efficient, productive and flexible. In traditional environmental monitoring workflows, single-bagged plates are decontaminated and stored in the isolator. Limited space in the isolator allows storage of only a small supply of ready-to-use plates. When this supply runs out, workflows are interrupted for...

Merck, a leading science and technology company, reported record results for 2015, emerging stronger from the transformation process that started in 2007. Net sales and EBITDA pre exceptionals were higher than ever before in Merck’s history of nearly 350 years.

“2015 was not only an eventful, but above all a very successful year for Merck. We again achieved profitable growth. By acquiring Sigma-Aldrich, we successfully completed the portfolio realignment of recent years. In immuno-oncology, we initiated six pivotal clinical trials. Research advances and future-oriented investments form the foundation for future success. And our new bold and vibrant branding shows what makes Merck unique,” said Karl-Ludwig Kley, Chairman of the Executive Board....

Merck, a leading science and technology company launch a range of new products for separation and analysis

The innovations include high performance liquid chromatography (HPLC) and capillary gas chromatography (GC) columns, and tools for effective analysis of water and easier sample preparation. "We are committed to providing innovations that help our customers solve their toughest problems, advance science and accelerate access to health care around the world," said Udit Batra, CEO of Merck's life science business

Merck Millipore's heipha ICRplus Neutralizer A contact plates improve detection of microorganisms on disinfected surfaces in isolators and cleanrooms.

Common disinfectants may contain residues from a variety of sources that inhibit the detection of microorganisms during surface monitoring, which can lead to false negative results. Heipha Neutralizer A ICRplus contact plates allow the detection of microorganisms in the presence of many disinfectants, including those which cannot be sufficiently inactivated by common neutralizers, such as polysorbate 80, lecithin, histidine and thiosulfate...

Merck Millipore, the Life Science division of Merck, has introduced the SNAP i.d.® 2.0 Protein Detection System for Immunohistochemistry (IHC), which streamlines immunohistochemistry workflows and significantly decreases slide handling time.

The system enables parallel processing of up to 24 tissue slides at a time, making it easier to apply consistent conditions and reduce potential process variability inherent in manual IHC methods. The system's intuitive format reduces slide handling and speeds wash steps during blocking, washing, antibody incubation and labeling. A controlled vacuum force removes solutions evenly from all slides at once, in seconds. This approach systemizes the handling of...

Merck Millipore, the Life Science division of Merck, has launched the EZ-Fit™ Filtration Unit, a ready-to-use, disposable filtration device for bioburden testing.

The system is faster and more efficient than traditional methods, resulting in increased reliability and streamlined workflows. The unit, which conforms to international standards (EP/USP) and water testing regulations, can be used for filtration of liquid samples including water, raw materials, in-process samples and final products. "The EZ-Fit™ Filtration Unit represents the latest addition to our comprehensive portfolio of products that facilitate and...

Polyplus-transfection SA, a privately-held company developing innovative technologies for molecular and cellular biology and Merck, a leading pharmaceutical, chemical and life science company with total revenues of EUR 11.2 billion in 2012, announce today a global prior use license agreement and extended supply agreement for Polyplus-transfection’s polyethylenimine (PEI) based transfection reagents. Financial details were not disclosed.

Polyplus-transfection has granted Merck rights to the prior use of PEI for transfection. Polyplus-transfection will also supply Merck sites worldwide with batches of high quality linear PEI transfection reagent. The reagent is specifically formulated and subject to appropriate quality controls (transfection activity and microbiological tests). These ensure reliable, safe and reproducible protein production in medium to large scale....