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Analysis of commercial monoclonal antibodies by microLC-MS/MS
Are you required to analyse very small sample amounts? Or do you need to analyse very low concentrations of antibodies in different kinds of matrices?
By using of microLC-MS/MS, only a very small amount of valuable samples, e.g. solutions prepared for patient application (usually a dilution of the dosage form), is required to identify and quantify. In addition, microLC-MS/MS can also be used to monitor residues on surfaces or materials in hospitals, pharmacies or laboratories that prepare solutions for patient application.
In this application note, YMC-Triart Bio C4 is used in YMC capillary column format to analyse and identify intact commercial MAbs, such as rituximab (MabThera®) or bevacizumab (Avastin®), by microLC-MS/MS.
Download the application note 'Analysis of commercial monoclonal antibodies by microLC-MS/MS' with the full method details for more information.
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