Follow us...


Search News Archives

Monthly Newsletter


Lab Bulletin May Newsletter

view the latest issue


News Channels


New Laboratory Products


Lab News


Microscopy & Image Analysis


Separation Science


Research & Case Studies






Events | Webinars




Conferences | Events

Dionex Demonstrates a Reliable Automated Solution for Phosphopeptide-Enrichment Applications

Dionex is proud to announce a new method to selectively isolate and enrich phosphopeptides from a peptide digest. Application Update 173: Enrichment and Identification of Chicken Ovalbumin Phosphopeptides by Immobilized Metaldemonstrates use of immobilized metal affinity chromatography (IMAC) in the ferric Affinity and Reversed-Phase Chromatographies form and exploits the affinity of the phosphopeptide phosphate group to ferric ions immobilized on the ProPac® IMAC-10 stationary phase of a Dionex UltiMate® 3000 high-performance liquid chromatography (HPLC) system.

Characterizing the phosphoproteome is key to understanding cellular degeneration associated with certain types of cancer. Although a variety of methods are currently used to separate phosphorylated from unphosphorylated species, the overlap between methods is poor, suggesting that each approach isolates a different subset of the phosphoproteome. This update demonstrates optimization of IMAC elution conditions for ovalbumin phosphopeptides, thus providing a reliable and easy-to-use solution for routine phosphopeptide- enrichments applications. This method also may be used to characterize phosphoproteins.

For more details, visit

Dionex (NASDAQ:DNEX) is a global leader in the manufacturing and marketing of liquid chromatography and sample preparation systems, consumables, and software for chemical analysis. The company's systems are used worldwide in environmental analysis and by the life sciences, chemical, petrochemical, food and beverage, power generation, and electronics industries. Our expertise in applications and instrumentation helps analytical scientists to evaluate and develop pharmaceuticals, establish environmental regulations, and produce better industrial products.

ProPac and UltiMate are registered trademarks of Dionex Corporation.



Popular this Month...

Our Top 10 most popular articles this month


Today's Picks...




Looking for a Supplier?

Search by company or by product


Company Name:




Please note Lab Bulletin does not sell, supply any of the products featured on this website. If you have an enquiry, please use the contact form below the article or company profile and we will send your request to the supplier so that they can contact you directly.

Lab Bulletin is published by newleaf marketing communications ltd




Media Partners