VICI Valco’s Cheminert High Pressure PEEK?Fittings are rated at 5000 psi with fingertight nuts, well beyond the burst strength of most PEEK tubing.
The taper angle and detail design conform to the industry standard established by the Valco line. The Cheminert UHPLC Fitting designs permit direct connection of 360 micron OD fused silica, PEEK, stainless, or electroformed nickel tubing without having to use troublesome liners. Because of the fitting’s compact size and fine 2-56 threads, a leak-free connection that seals at pressures well in excess of 20,000 psi can be easily formed with...
At the European Winter Conference on Plasma Spectrochemistry in Münster the Company launches two new mass spectrometers for its global sales
Analytik Jena AG expands its product range: only half a year after the acquisition of the ICP-MS business of the Bruker Corporation in September 2014, Analytik Jena introduces two new ICP-MS products (inductively coupled plasma for use in mass spectronomy) PlasmaQuant ® MS and PlasmaQuant ® MS Elite.The instruments will be unveiled at the European Winter Conference on Plasma Spectrochemistry (EWCPS)...
Genevac has launched a web page that brings together the latest technological innovations and application advances, with links to reference papers, detailing how new fast, safe evaporative sample preparation techniques are benefiting metabolism and toxicology studies.
Visitors to the new web page can gain an insight into how Genevac evaporators are providing fast, safe sample preparation, free from artefact, contamination or loss, from simple concentration or drying of solvent extracts from tissue samples right through to quantitative screening of workers or athletes for the presence of a drug...
Magritek, a leading provider of compact NMR and MRI instruments, report on the use of their Spinsolve Benchtop NMR spectrometer for reaction monitoring studies in the Cronin Group in the Chemistry Department of the University of Glasgow.
Professor Lee Cronin holds the Regius Chair of Chemistry at the University of Glasgow. Research in the Cronin Group is motivated by the fascination for complex chemical systems and the desire to construct complex functional molecular architectures that are not based on biologically derived building blocks. They are developing a new approach to the chemical sciences which they call Chemical Cybernetics. This combines...
A new whitepaper from Malvern Instruments provides detailed guidance on the analytical technologies that help to accelerate oral solid dosage (OSD) product formulation to a successful conclusion.
‘Analytical techniques with a place in the oral solid dosage formulation toolkit’ reviews the regulatory and QbD framework associated with OSD formulation and demonstrates how Malvern systems can be used to generate the data required. The goal of formulation is to incorporate an identified drug substance into a successful pharmaceutical product. The regulatory framework for OSD products highlights the need to comprehensively...
Flame brings flexible sensing power to research and teaching labs
Ocean Optics has launched a spectrometer line that combines decades of miniature spectrometer design expertise with industry-leading manufacturing techniques. The Flame spectrometer delivers high thermal stability and low unit to unit variation without compromising the flexibility and configurability that are the hallmark of modular, miniature spectrometers. Features such as interchangeable slits, indicator LEDs and simpler device...
Taking pictures with your camera you may find that images often look okay on a first glimpse, but when zooming in fine details are barely noticeable.
In contrast, the high information density of high resolution images will reveal even the smallest details. Since the introduction of ICP optical emission spectrometry, the spectral resolution has been a main concern with respect to accuracy and sensitivity. The wealth of emission lines from the plasma frequently leads to overlapping between lines of the analyte and that of accompanying elements. In many sample matrices such spectral interferences...
ACE UltraCore SuperC18 has been specifically designed for demanding MS application work and is based on high efficiency, low back pressure solid-core particles with a unique Encapsulated Bonding Technology (EBT).
This technology dramatically increases ligand coverage on the solid-core silica surface and consequently provides a number of key advantages for MS users. Advantage Number 1 for MS Users: Improved Peak Shape and MS Signal Intensity - ACE UltraCore SuperC18 columns have earned a well deserved reputation for delivering highly efficient symmetrical peaks, even with the most challenging of molecules. The use of a highly efficient column exhibiting minimal peak tailing will result in an improved MS signal response.....
Cogent Diol and Cogent UDA (undecanoic acid) are the latest additions to the MicroSolv range of stationary phases for high performance liquid chromatography (HPLC). Both columns are based on MicroSolv’s unique TYPE-C Silica and silica hydride surface chemistry.
Cogent Diol is a 4um diol bonded phase suitable for the reversed-phase or aqueous normal-phase (ANP) analysis of polar compounds and is LC-MS compatible. Columns show fast equilibration between gradient runs and can be successfully used in studies of pathways in human pathology.
The Qsep100 DNA Analyzer from Precision Biosystems performs rapid, high sensitivity assays at lower cost per sample compared to similar systems.
Capillary gel electrophoresis technology is recognized as an optimal approach to performing post PCR separation, detection of DNA and RNA fragments and assessing the quality of genomic DNA. The Qsep100 DNA Analyzer, by Precision Biosystems, uses micro-capillary gel electrophoresis combined with fluorescence detection, and is capable of performing 200 assays automatically as quickly as 2 minutes per sample. With costs per sample as low as $0.10 each, Qsep100 is...
Thermo Scientific MAbPac HIC-20 and MAbPac HIC-Butyl Columns Join Lineup
Laboratories characterizing monoclonal antibodies (mAb) now have additional hydrophobic interaction chromatography (HIC) selectivity options, thanks to the expanded family of Thermo Scientific MAbPac HIC HPLC columns. New Thermo Scientific MAbPac HIC-20 and MAbPac HIC-Butyl columns join the company’s line of columns for monoclonal antibody analysis, a response to customer demand for additional selectivity options for...
Advanced Chromatography Technologies Limited have launched new 0.5mm and 1.0mm i.d. microbore ACE UltraCore columns, based on high efficiency, low back pressure solid-core particles with unique Encapsulated Bonding Technology (EBT). These columns have been specifically designed for demanding MS application work and deliver extremely efficient, highly symmetrical peak shapes, which ensures improved MS signal intensity. The SuperC18 phase is...
J. G. Finneran Vial Loaders, manufactured from environmentally-friendly, recycled materials, provide a fast and convenient way of loading vials into all of your 96-well plates.
Finneran Vial Loaders are available with conical or flat bottom polypropylene or glass vials for our patented Multi-TierTM Micro Plate System, or glass conical or tapered bottom vials for many popular 96-Square Deep Well plates. Insert volume sizes range from 350µL glass conical, 6x32mm pulled-point inserts, to volumes of 2.0mL. The inserts are available in clear or amber, with an optional marking spot for easier sample identification....
The MiniVap™ blowdown evaporator from Porvair Sciences takes just minutes to remove volatile organic solvents from your 96-well microplates.
The MiniVap™ is the perfect tool for labs where smaller numbers of individual plates need drying. Incorporating advanced evaporator head technology and an innovative manifold design, which directly injects heated nitrogen into each well of a 96-well microplate simultaneously, the MiniVap enables researchers to remove the traditional laboratory ‘bottleneck’ of solvent evaporation from microplates prior to analysis or reconstitution in buffer...
Merck Millipore, the Life Science business of Merck, today announced the introduction of its AFS® 40E / 80E / 120E and 150E water purification systems.
These new systems have been developed to provide clinical laboratories with an economical and reliable water purification solution for daily water volumes of up to 3000 L. The AFS® 40E / 80E / 120E and 150E systems rely on two powerful technologies to produce water quality meeting Clinical and Laboratory Standards Institute® (CLSI®) Clinical Laboratory Reagent Water standards. State-of-the-art, proven Elix® electrodeionization (EDI) technology ensures constant water quality...
SampleGenie 4 is the latest version of Genevac’s unique technology for direct concentration of large sample volumes into vials, designed for use in the Rocket Synergy Evaporator.
SampleGenie technology enables large sample volumes to be dried directly into vials, eliminating a number of time-consuming sample handling steps and the attendant risk of errors. The latest generation SampleGenie further enhances the exceptional capabilities of the original design. Accommodating sample volumes of up to 250ml, and featuring a new vial adapter insert to suit a range of vials from 12mm to 28mm diameter and up to...
A completely new gel permeation/size exclusion chromatography (GPC/SEC) platform from Malvern Instruments breaks new ground in delivering the high performance, ease of use and productivity demanded in today’s analytical laboratories.
Malvern’s innovative OMNISEC platform integrates highly efficient sample separation via the OMNISEC RESOLVE module and high sensitivity analysis using OMNISEC REVEAL, a fully integrated multi-detector array. The system has applications wherever there is a need for detailed analysis and understanding of natural or synthetic polymers, proteins and macromolecules. GPC/SEC is a two-step analytical process that involves separating a...
Reliable containment of samples is crucial and the integrity, cleanliness and consistency of vials is critical for accurate analysis.
Many analysts think of vials as simple components that do not affect results which is an easy mistake to make…until something goes wrong. Using vials that are not fit for purpose can have a significant impact on the quality of analysis and there are a number of issues to look for in uncertified autosampler vials, including: Non-uniform bottom thickness which can damage needles and cause inconsistent sample draw...
Biologics characterisation from cradle to grave 12th – 13th May 2015 MedImmune Cambridge
Complete characterisation of proteins and peptides is essential across a wide range of industries and applications. The emergence of protein based bio-pharmaceuticals has resulted in increased reliance on the chromatographic and spectrometric techniques used to determine the key quantitative and qualitative attributes of such complex therapeutic entities.
As the importance of steroids in the regulation of bioprocesses has increased so has the demand for fast screening methods for their detection.
HPLC is a highly regarded analytical technique for pharmaceutical applications due to its unrivalled analytical validation characteristics; including accuracy, precision, limit of detection, specificity, linearity and range, and ruggedness. The high throughput demands of quantitative steroid analysis require faster run times and as a result there has been a focus on the development of fast HPLC screening methods to detect steroids...
Researchers at the University of Lethbridge, Alberta, Canada, are using Viscotek multi-detector Gel Permeation/Size Exclusion Chromatography (GPC/SEC) (Malvern Instruments, UK) to analyze performance defining polymer features in the development of novel polymer coatings for metal nanoparticles.
“Multi-detection GPC/SEC helps us to monitor and control reaction conditions to engineer advanced polymer coatings which stabilize nanoparticle suspensions to ease their handling and preserve their industrial value,” said Dr. Farhad Faghihi, Research Associate at the University of Lethbridge. “GPC/SEC is the only technique that we have to determine molecular weight and molecular weight distribution with the speed and accuracy...
New Clarit-E® Choice Stretch Horizontal Electrophoresis Tank
If you need to separate samples with very similar molecular weights, the new Clarit-E® Choice Stretch Electrophoresis Gel Tanks from Alpha Laboratories Ltd. provide the perfect solution. Plus, when you need high throughput, these tanks allow up to 350 samples to be resolved per gel. The extended run lengths of the Choice Stretch Horizontal Tanks allow restriction fragments or other close molecular weight sample bands...
The taper angle and detail design conform to the industry standard established by the Valco line. The Cheminert UHPLC Fitting designs permit direct connection of 360 micron OD fused silica, PEEK, stainless, or electroformed nickel tubing without having to use troublesome liners. Because of the fitting’s compact size and fine 2-56 threads, a leak-free connection that seals at pressures well in excess of 20,000 psi can be easily formed with...
Analytik Jena AG expands its product range: only half a year after the acquisition of the ICP-MS business of the Bruker Corporation in September 2014, Analytik Jena introduces two new ICP-MS products (inductively coupled plasma for use in mass spectronomy) PlasmaQuant ® MS and PlasmaQuant ® MS Elite.The instruments will be unveiled at the European Winter Conference on Plasma Spectrochemistry (EWCPS)...
Visitors to the new web page can gain an insight into how Genevac evaporators are providing fast, safe sample preparation, free from artefact, contamination or loss, from simple concentration or drying of solvent extracts from tissue samples right through to quantitative screening of workers or athletes for the presence of a drug...
Professor Lee Cronin holds the Regius Chair of Chemistry at the University of Glasgow. Research in the Cronin Group is motivated by the fascination for complex chemical systems and the desire to construct complex functional molecular architectures that are not based on biologically derived building blocks. They are developing a new approach to the chemical sciences which they call Chemical Cybernetics. This combines...
‘Analytical techniques with a place in the oral solid dosage formulation toolkit’ reviews the regulatory and QbD framework associated with OSD formulation and demonstrates how Malvern systems can be used to generate the data required. The goal of formulation is to incorporate an identified drug substance into a successful pharmaceutical product. The regulatory framework for OSD products highlights the need to comprehensively...
Ocean Optics has launched a spectrometer line that combines decades of miniature spectrometer design expertise with industry-leading manufacturing techniques. The Flame spectrometer delivers high thermal stability and low unit to unit variation without compromising the flexibility and configurability that are the hallmark of modular, miniature spectrometers. Features such as interchangeable slits, indicator LEDs and simpler device...
In contrast, the high information density of high resolution images will reveal even the smallest details. Since the introduction of ICP optical emission spectrometry, the spectral resolution has been a main concern with respect to accuracy and sensitivity. The wealth of emission lines from the plasma frequently leads to overlapping between lines of the analyte and that of accompanying elements. In many sample matrices such spectral interferences...
This technology dramatically increases ligand coverage on the solid-core silica surface and consequently provides a number of key advantages for MS users. Advantage Number 1 for MS Users: Improved Peak Shape and MS Signal Intensity - ACE UltraCore SuperC18 columns have earned a well deserved reputation for delivering highly efficient symmetrical peaks, even with the most challenging of molecules. The use of a highly efficient column exhibiting minimal peak tailing will result in an improved MS signal response.....
Cogent Diol is a 4um diol bonded phase suitable for the reversed-phase or aqueous normal-phase (ANP) analysis of polar compounds and is LC-MS compatible. Columns show fast equilibration between gradient runs and can be successfully used in studies of pathways in human pathology.
Capillary gel electrophoresis technology is recognized as an optimal approach to performing post PCR separation, detection of DNA and RNA fragments and assessing the quality of genomic DNA. The Qsep100 DNA Analyzer, by Precision Biosystems, uses micro-capillary gel electrophoresis combined with fluorescence detection, and is capable of performing 200 assays automatically as quickly as 2 minutes per sample. With costs per sample as low as $0.10 each, Qsep100 is...
Laboratories characterizing monoclonal antibodies (mAb) now have additional hydrophobic interaction chromatography (HIC) selectivity options, thanks to the expanded family of Thermo Scientific MAbPac HIC HPLC columns. New Thermo Scientific MAbPac HIC-20 and MAbPac HIC-Butyl columns join the company’s line of columns for monoclonal antibody analysis, a response to customer demand for additional selectivity options for...
Advanced Chromatography Technologies Limited have launched new 0.5mm and 1.0mm i.d. microbore ACE UltraCore columns, based on high efficiency, low back pressure solid-core particles with unique Encapsulated Bonding Technology (EBT). These columns have been specifically designed for demanding MS application work and deliver extremely efficient, highly symmetrical peak shapes, which ensures improved MS signal intensity. The SuperC18 phase is...
Finneran Vial Loaders are available with conical or flat bottom polypropylene or glass vials for our patented Multi-TierTM Micro Plate System, or glass conical or tapered bottom vials for many popular 96-Square Deep Well plates. Insert volume sizes range from 350µL glass conical, 6x32mm pulled-point inserts, to volumes of 2.0mL. The inserts are available in clear or amber, with an optional marking spot for easier sample identification....
The MiniVap™ is the perfect tool for labs where smaller numbers of individual plates need drying. Incorporating advanced evaporator head technology and an innovative manifold design, which directly injects heated nitrogen into each well of a 96-well microplate simultaneously, the MiniVap enables researchers to remove the traditional laboratory ‘bottleneck’ of solvent evaporation from microplates prior to analysis or reconstitution in buffer...
These new systems have been developed to provide clinical laboratories with an economical and reliable water purification solution for daily water volumes of up to 3000 L. The AFS® 40E / 80E / 120E and 150E systems rely on two powerful technologies to produce water quality meeting Clinical and Laboratory Standards Institute® (CLSI®) Clinical Laboratory Reagent Water standards. State-of-the-art, proven Elix® electrodeionization (EDI) technology ensures constant water quality...
SampleGenie technology enables large sample volumes to be dried directly into vials, eliminating a number of time-consuming sample handling steps and the attendant risk of errors. The latest generation SampleGenie further enhances the exceptional capabilities of the original design. Accommodating sample volumes of up to 250ml, and featuring a new vial adapter insert to suit a range of vials from 12mm to 28mm diameter and up to...
Malvern’s innovative OMNISEC platform integrates highly efficient sample separation via the OMNISEC RESOLVE module and high sensitivity analysis using OMNISEC REVEAL, a fully integrated multi-detector array. The system has applications wherever there is a need for detailed analysis and understanding of natural or synthetic polymers, proteins and macromolecules. GPC/SEC is a two-step analytical process that involves separating a...
Many analysts think of vials as simple components that do not affect results which is an easy mistake to make…until something goes wrong. Using vials that are not fit for purpose can have a significant impact on the quality of analysis and there are a number of issues to look for in uncertified autosampler vials, including: Non-uniform bottom thickness which can damage needles and cause inconsistent sample draw...
Complete characterisation of proteins and peptides is essential across a wide range of industries and applications. The emergence of protein based bio-pharmaceuticals has resulted in increased reliance on the chromatographic and spectrometric techniques used to determine the key quantitative and qualitative attributes of such complex therapeutic entities.
HPLC is a highly regarded analytical technique for pharmaceutical applications due to its unrivalled analytical validation characteristics; including accuracy, precision, limit of detection, specificity, linearity and range, and ruggedness. The high throughput demands of quantitative steroid analysis require faster run times and as a result there has been a focus on the development of fast HPLC screening methods to detect steroids...
“Multi-detection GPC/SEC helps us to monitor and control reaction conditions to engineer advanced polymer coatings which stabilize nanoparticle suspensions to ease their handling and preserve their industrial value,” said Dr. Farhad Faghihi, Research Associate at the University of Lethbridge. “GPC/SEC is the only technique that we have to determine molecular weight and molecular weight distribution with the speed and accuracy...
If you need to separate samples with very similar molecular weights, the new Clarit-E® Choice Stretch Electrophoresis Gel Tanks from Alpha Laboratories Ltd. provide the perfect solution. Plus, when you need high throughput, these tanks allow up to 350 samples to be resolved per gel. The extended run lengths of the Choice Stretch Horizontal Tanks allow restriction fragments or other close molecular weight sample bands...