Artificial sweeteners are added to many foods and cosmetic products. As useful as they are in these areas, they pollute wastewater and groundwater. Therefore, powerful LC-MS/MS applications for the most common artificial sweeteners acesulfame, saccharin and cyclamateare essential. Find out more about how to implement an ultra-fast analysis routine in your lab by downloading the application note...
New treatment re-sensitises advanced prostate cancers to treatment by stopping tumours hijacking myeloid white blood cells to help fuel their growth. Prostate cancer’s resistance to treatment can be reversed in some patients by stopping hijacked white blood cells from being ‘pulled into’ tumours, according to new research published in Nature. In an early clinical trial, researchers showed that blocking the messages cancer uses to hijack white blood cells can re-sensitise a subset of advanced prostate cancers to treatment – shrinking tumours or halting their growth...
The Chief Executive of one of Britain’s leading tissue engineering companies has co-authored a book entitled Advances in Cultured Meat Technology that explores the potential of cultured meat production in solving food security challenges and helping to achieve climate targets. With the global population estimated to reach 9 billion by 2050, Professor Che Connon, Chief Executive of the pioneering UK-based clinical and cellular agriculture company 3D Bio-Tissues together with Professor Mark and Dr Chris Bryant...
INTEGRA Biosciences has awarded 31 EVOLVE manual pipettes, GRIPTIPS®pipette tips worth US $1000, and lab accessories to the bioanalytical company DNTOX as part of its recent ‘INTEGRA supports start-ups’ competition, which ran until April 2023. The pipettes will greatly streamline the company’s neurotoxicological hazard assessments, helping to increase its testing capacity and advance research in this vital area...
The Pistoia Alliance, a global, not-for-profit alliance that advocates for greater collaboration in life sciences R&D, is releasing the results of a new global survey conducted in partnership with Open Pharma Research, organizers of the Lab of the Future Congress, examining lab technology investment, barriers, and benefits. The Alliance surveyed 200 experts spanning Europe, the Americas and APAC from its network of members, including lab professionals and R&D experts from top pharma companies, medium enterprises and life science start-ups...
Charles River Laboratories International, Inc. and PathoQuest SAS, a leader in the development and provision of next-generation sequencing (NGS) testing services for biopharmaceuticals, have announced the publication of the results of a seminal study in Vaccine. This unique study demonstrated that PathoQuest’s proprietary, good manufacturing practice (GMP) grade NGS-based assay had a greater capability of detecting viral contaminants when compared to in vivo assays...
Four astronauts ended a six-month science expedition onboard the International Space Station (ISS) with the successful splashdown of the SpaceX Dragon Endeavour spacecraft off the coast of Florida. During their time in space, the crew members worked on dozens of research investigations and technology demonstration projects that were sponsored by the ISS National Laboratory...
The Institute for Research and Innovation in Biomedicine (IRIB) focuses on developing innovative technologies for diagnosing, treating, and preventing diseases. Its research programs are centered around several themes, including cancer, infectious diseases, neurodegenerative diseases, and regenerative medicine. Located in Rouen, France, the IRIB brings together researchers and experts from various fields, including biology, chemistry, physics, and medicine, to collaborate on cutting-edge research projects....
Researchers at the Wellcome Centre for Mitochondrial Research (WCMR), within the Faculty of Medical Sciences at Newcastle University in the UK, have chosen INTEGRA Biosciences’ VOYAGER adjustable tip spacing pipette to support their research on mitochondrial diseases. The multidisciplinary team is using the equipment to streamline various steps in its high throughput screening assays to identify drugs that are capable of rescuing mitochondrial function to improve the quality of life of those living with a mitochondrial condition...
Chromatographic purification on a research scale is a must-have in many areas such as academia and pharmaceutical research. However, this can be very time consuming. Therefore, effective development of the purification method is essential. These guidelines from YMC demonstrate the main steps for an effective purification method development...
Axis Healthcare, a family-run care facility in Oklahoma, has introduced VOYAGER adjustable tip spacing pipettes from INTEGRA Biosciences into its PCR laboratory workflows. These multichannel pipettes offer the laboratory a straightforward and easy-to-use liquid handling solution to provide accurate and high throughput testing as part of a holistic strategy to support patients in overcoming opioid addiction...
A team of scientists, from the University of Bath’s Department of Chemistry and Institute for Sustainability have found a way to create two of the world’s most common painkillers, paracetamol and ibuprofen, out of a compound found in pine trees, which is also a waste product from the paper industry. It is perhaps not widely known that many common pharmaceuticals are manufactured using chemical precursors derived from crude oil, presenting a niche sustainability challenge as the world targets Net Zero...
A new six-month science expedition in low Earth orbit (LEO) begins when four astronauts launch to the International Space Station (ISS) as part of NASA’s SpaceX Crew-7 mission. While onboard the space station, the Crew-7 astronauts, who will be part of Expeditions 69 and 70, will perform a variety of investigations sponsored by the ISS National Laboratory. This 7th rotational crewed mission from SpaceX, which is part of NASA’s Commercial Crew Program, is scheduled to launch from NASA’s Kennedy Space Center in Florida...
Promega scientists contribute to new research to improve precision and efficiency of groundbreaking gene editing technique. A new study published in Nature Communications demonstrates how small molecule inhibitors can be used to improve the precision and efficiency of CRISPR-Cas9 gene editing. The results demonstrate how this groundbreaking technique can be enhanced by using two inhibitors to boost insertion rates and reduce off-target effects...
Growing demand for analytical laboratory services (and the impact of the COVID-19 pandemic) will see the industry grow globally to about $492 million by 2027. Batch Release Testing shows the biggest growth in the market, estimated to increase at 9% Compound Annual Growth Rate (CAGR). To keep up with the expected demand over the next seven years, you’ll need to know all the latest techniques and analytical methods that could affect your SPE workflows. Here, Gilson discuss some of the latest considerations for your SPE processes...
Research labs are complicated environments and it is not always clear what can be done to improve sustainability. To date, most of the discussion around sustainability has focussed on the energy efficiency of instruments and equipment, such as fume hoods and cryogenic freezers. While this is important, it means that things like chemical and solvent selection are overlooked. Here Paul Vanden Branden, Director at SciMed, an exhibitor at Lab Innovations 2023 and member of the show’s advisory board, discusses...
Researchers in the Cho Lab at Seoul National University’s College of Veterinary Medicine, are using the VACUSAFE safe aspiration system and VACUSIP portable aspiration system from INTEGRA Biosciences to help them culture organoids from cancer-stricken domesticated dogs as part of a comparative medicine research initiative. Collaborating closely with the university’s veterinary practitioners, researchers aim to expand the number of canine NGS datasets, in a bid to advance our understanding of the biological progression of tumors...
Advances in technology mean that moving from microscopes to digital alternatives can now be achieved without sacrificing image quality. But this isn’t about the technology. Professor Gina Zini, reflects on the key benefits of digital developments, including better quality screening, saved time for busy morphologists, better clinical collaboration, improved training, and sharing expertise with developing countries...
Powders are used in all production processes of solid dosage forms like tablet or dry powder inhaler (DPI) manufacturing processes. Among all the powder properties, permeability, which is the capacity of a fluid (air) to pass through a powder bed, plays a crucial factor in different pharmaceutical processes. In the die filling of tablet manufacturing, the permeability determines the powder flowability during the displacement of the powder within the die and the capacity of the powder to pack in the die...
The International Space Station (ISS) National Laboratory is collaborating with NASA on a solicitation to advance research on cancer and other diseases. ISS National Lab Research Announcement (NLRA) 2023-10: Igniting Innovation: Science in Space to Cure Disease on Earth, in partnership with NASA’s Biological and Physical Sciences Division, will offer resource allocation and up to $5 million in total funding for an expected two to four awards for multiflight translational and transformative research and technology development projects...
New study shows that graphene-based TENGs could finally unlock nature’s wasted energy. Scientists may have finally found a solution to effectively harvesting energy from humans into electrical energy. Researchers from the Institute of Thin Films, Sensors and Imaging (ITFSI) from the University of the West of Scotland (UWS) explored the use of the 3D graphene foam material Gii™ by Integrated Graphene as an active layer in an energy generator (known as a TENG)...
AMSBIO, a leading supplier of human cell lines and research tools, is proud to announce its collaboration with WARR Space Labs, a student group from the Technical University of Munich (TUM). The students undertook an exciting project aimed at advancing our understanding of neurodegenerative disorders, particularly Alzheimer’s disease, through spaceborne experiments.