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All articles from Cleaver Scientific Ltd

  Flexible Denaturing Gradient Gel Electrophoresis (DGGE) System

The next generation OmniPAGE VS20WAVE-DGGE from Cleaver Scientific is a flexible Denaturing Gradient Gel Electrophoresis (DGGE) system. Modular in design the system can be simply adapted to perform most single-base pair mutation detection techniques that are used in DNA mutation analysis.

cleaverscientificDenaturing gradient gel electrophoresis (DGGE) is a molecular fingerprinting method that separates polymerase chain reaction generated DNA products. The polymerase chain reaction (PCR) of environmental DNA can generate templates of differing DNA sequence that represent many of the dominant microbial organisms. However, since PCR products from a given reaction are of similar size (bp), conventional separation by agarose gel electrophoresis results only in a single DNA band that is largely non-descriptive. DGGE can overcome this limitation by separating PCR products based on sequence differences that results in differential denaturing characteristics of the DNA....

 

  Sterile Workspace for Preparation of RNA & DNA Samples

Cleaver Scientific has supplied a UV Sterilization Cabinet to Touchlight Genetics (Hampton, UK) who had sought a sterile workspace for the preparation of their RNA and DNA samples and templates.

CleanView range of UV Sterilisation CabinetsTouchlight Genetics Ltd. is a rapidly expanding UK biotech company that has developed an entirely enzymatic process of DNA synthesis that is fast, efficient and has a yield that can easily meet growing demand for DNA. The company's dbDNAℱ expression cassettes eliminate the need for bacterial sequences and antibiotic resistance genes in the production of biological therapies, satisfying stated concerns from the industry’s main...

 

  New Horizontal Polyacrylamide Gel Electrophoresis (hPAGE) System

Cleaver Scientific announces the introduction of a horizontal polyacrylamide gel electrophoresis (hPAGE) system developed in collaboration with the Kirkhouse Trust, an organisation supporting research and education in the biological sciences.

cleaverscientificpr9Whilst vertical systems are commonly used for polyacrylamide gel electrophoresis, this newly developed unit’s horizontal format allows for a large number of samples to be run simultaneously and combines this with the greater resolution of polyacrylamide compared with agarose.  The main advantage of the system is that it is very simple to pour and cast the polyacrylamide gels which takes away some of the complexity normally associated with vertical gel casting....

 

  50% off High Grade Agarose for Nucleic Acid Electrophoresis

Cleaver Scientific CleverGEL

Hurry offer expires 30th June!

Cleaver Scientific, specialists in gel electrophoresis has introduced a new range of high grade agarose for nucleic acid electrophoresis. CleverGEL is a new environmentally friendly agarose suitable for routine analysis of nucleic acids using standard electrophoretic procedures. Manufactured by a process which excludes organic solvents harmful to marine life, CleverGEL is far kinder to the environment than conventional agarose. Try Before you Buy

 

  Safer, More Convenient DNA Electrophoresis

The 'Safe' Series of products from Cleaver Scientific have been designed to make DNA electrophoresis procedures safer, more convenient and more economical to run.

cleaver scientificIt is widely acknowledged that the main hazards of traditional DNA gel electrophoresis lie in the use of Ethidium Bromide stain, a known mutagen and carcinogen, and using UV illumination sources which can cause eye and skin damage. Furthermore, traditional DNA electrophoresis is usually performed without researchers knowing much about what is happening on the gel unit until it is stopped and checked. This blind 'stop and start’ process, where an...

 

  Versatile Integrated System for Gel Electrophoresis

The VS20 WAVE from Cleaver Scientific is a single tank electrophoresis system which provides a fully integrated solution for vertical PAGE, tube gel IEF and electro blotting.

VS20 WAVEInterchangeable modular inserts on the innovative VS20 WAVE allow users to combine vertical PAGE with capillary gel IEF to perform 2D electrophoresis, followed by Western transfer for enhanced sensitivity. In addition to unmatched operational versatility the VS20 WAVE also offers ultra-fast set-up. Proprietary vertical screw-clamp technology reduces the number of screws required for set up compared to traditional electrophoresis systems, thereby dramatically reducing assembly time. The ergonomic design of the VS20 WAVE aids both handling and set-up, while its built-in inner buffer chamber allows set-up to be completed without the inclusion of a top tank or upper buffer chamber....

 

  Affordable High Performance Gel Documentation & Analysis

The omniDOC series of gel documentation and analysis systems from Cleaver Scientific provide researchers with a quick, simple and flexible solution for their gel documentation needs in a compact and affordable benchtop unit.

omnidoc cleaverscientificUniquely combining high performance, leading edge features and affordability the omniDOC series provide an easy-to-use, yet powerful gel imaging system that satisfies the needs of most laboratories. The omniDOCi shares all the same features as the standard omniDOC but with the added benefit of wireless connectivity enabling the system to be run in a darkroom from a remote PC or tablet....

 

  New Catalogue for Electrophoresis Equipment & Supplies

Cleaver Scientific, a leading manufacturer of innovative electrophoresis equipment and related products for the life science market, has introduced the 5th edition of its product catalogue.

Cleaver Catalogue 2015The new 2015 catalogue has been expanded to 156-pages to provide detailed information covering the company’s comprehensive range of instruments, chemicals and consumables for electrophoresis and general lab equipment for life science research. Intuitively organized into sections covering horizontal and vertical gel electrophoresis systems, blotting systems, power supplies, gel documentation apparatus, reagents, chemicals and associated general lab equipment the catalogue...

 

  Cleaver Scientific Helps in UK Fight Against Ebola

Cleaver Scientific reports that its horizontal electrophoresis equipment is being used on the frontline of the UK fight against Ebola

cleaverThe Cleaver Scientific MultiSUB electrophoresis system features in a recent ITV report on UK Government plans to step up Ebola screening of passengers arriving from West Africa at Heathrow and Gatwick airports as well as major rail terminus. At the Porton Down research centre in Wiltshire, UK - scientists are working on detecting and minimising the risk of the Ebola virus appearing in the UK. Currently researchers are analysing 10-15 blood samples / week taken from National Health Service (NHS) patients, all to date have proved negative for Ebola....

 

  Toxicity Test Technology Hits the Market

University of Leicester develops technique for high throughput screening of substances that could cause DNA damage.

  • New technology launches to the market
  • It allows for testing of drugs and cosmetics that could pose a risk to human health
  • Damage to DNA is assessed by technique
  • It provides a way of reducing reliance on animal testing
  • Leicester technique in association with Cleaver Scientific Ltd provides a high throughput method of assessing samples

 

  New COMPAC-50 HTP Comet Assay Tank on display at Lab Innovations

Visit Cleaver Scientific at Lab Innovations | Stand D8 and learn how to reduce your assay time by 60%

cleaverscientificpr2The COMPAC-50 marks the first of a new range of innovative systems designed specifically for rapid high throughput single cell gel electrophoresis. Developed in collaboration with the Oxidative Stress Group at the University of Leicester (Leicester, UK), the unique design of the COMPAC-50 enables simultaneous electrophoresis of up to 50 COMET Assay slides saving considerable lab space and reducing slide handling time by up to two-thirds when compared to previous standard methods. This would equate to a significant time-saving of up to 90% when handling 50 COMET Assay slides....

Visit Cleaver Scientific at Lab Innovations | Stand D8

 

  New High Throughput COMET Assay System

Cleaver Scientific has introduced the innovative new COMPAC-50 High Throughput COMET Assay system.

COMPAC-50Developed in collaboration with the Oxidative Stress Group at the University of Leicester (Leicester, UK), the unique design of the COMPAC-50 enables simultaneous electrophoresis of up to 50 COMET Assay slides saving considerable lab space and reducing slide handling time by up to two-thirds when compared to previous standard methods. This would equate to a significant time-saving of up to 90% when handling 50 COMET Assay slides.

 

  New Compact, Low-Cost Gel Image Capture & Documentation System

The latest products to be introduced by electrophoresis specialists CLEAVER SCIENTIFIC (CSL) are their new gel documentation and analysis systems omniDOC and omniDOCi. 

cleaverThese units provide researchers with a quick, simple and flexible solution for their gel documentation needs in a compact and affordable bench-top unit. The integral 5 megapixel camera combined with CSL basic gel analysis software ensures a perfect image every time along with the provision for image analysis.  By providing many of the features used by leading gel documentation brands, but without the added price premium, each omniDOC system provides a simple yet sophisticated imaging solution for most laboratories and most budgets....

 

  Fully Integrated GEL Electrophoresis System Saves Time & Space

The VS20 WAVE is a complete electrophoresis system which provides a fully integrated solution using one get tank and lid for vertical PAGE, tube gel IEF and electro blotting. 

VS20 WAVE - FULLY INTEGRATED GEL ELECTROPHORESIS SYSTEM SAVES TIME & SPACEAvailable from gel electrophoresis specialists CLEAVER SCIENTIFIC Ltd (CSL) the innovative VS20 Wave is designed to perform a variety of separations, ranging from first and second dimension SDS-PAGE to capillary tube gel IEF and electroblotting. Unlike other systems whose traditional clamping configurations require adjustment of as many as 24 screws to secure just two glass plates, the VS20 WAVE insert utilises only four screws to secure as many 20 x 20cm gels...

 

  Cleaver Scientific at Lab Innovations - Stand F8

Gel Electrophoresis specialists CLEAVER SCIENTIFIC will be exhibiting their range of innovative electrophoresis and related products at Lab Innovations - NEC, Birmingham 6th and 7th November 2013.

 Cleaver Scientific LTD Product Guide

Among the products on display will be the revolutionary “Safe” series of electrophoresis products including:- runView – Let’s you see your samples separate out in real time on your lab bench, no transport of gels or dark room required. runDoc – The self-contained, low-cost bench-top gel documentation system that allows the capture of gel images in real time. runSafe – A completely safe stain for DNA that also doubles up as the sample loading buffer. Once again, Cleaver Scientific will be running a prize draw. 1st prize is a Ipod and second prize a bottle of champagne!..

 

  Cleaver Scientific and Biocentre Collaboration in Hungary

Cleaver Scientific and Biocenter Collaboration is Appreciated at the University Of PĂ©cs in Hungary

Molecular background pictureGel Electrophoresis specialists CLEAVER SCIENTIFIC Ltd (CSL) and their Hungarian distributor Biocenter recently exhibited at and sponsored the 11th International Symposium on Vasoactive Intestinal Peptide (VIP) and Pituitary Adenylate Cyclase-Activating Peptide (PACAP) and related peptides. The event, staged at the University of Pécs in Hungary at the end of August, was an excellent example of the successful collaboration between CSL and their Hungarian distributor...

 

  3 Steps to Safer and Simpler DNA Gel Electrophoresis.

Helping to make DNA electrophoresis procedures safer, more convenient and more economical are the fundamental principles behind the development of the ‘Safe’ Series of products from CLEAVER SCIENTIFIC (CSL).

DNA gel Electrophoresis AB13-610Laboratories around the world will acknowledge that there are two main hazards with traditional DNA gel electrophoresis.  For example, the stain most commonly used is Ethidium Bromide which is a mutagen and carcinogen, whilst the illumination source most often used is Ultra Violet, which can cause eye and skin damage.  Furthermore, traditional DNA electrophoresis is usually performed without the researcher knowing much about what is happening on the gel unit until is stopped and checked...

 

  Precast Gels provide Speed, Convenience and Flexibility

Electrophoresis specialists CLEAVER SCIENTIFIC (CSL) have introduced a new range of 10 x 10cm Precast Gels which are ideally suited to all SDS-PAGE applications. PAGE-PRO Precast gels provide fast run times from 45 to 75 minutes and a superior performance compared to traditional Laemmli gels.

Cleaver-AB13-577PAGE-PRO gels have a specially formulated proprietary gel matrix composition which ensures their enhanced performance and a guaranteed shelf-life of a minimum of 12 months. Available in single and gradient percentage acrylamide compositions, PAGE-PRO gels are manufactured using an automated filling technique that ensures total reproducibility between batches.  They can also be used with standard Tris-MOPS, Tris-HEPES and Tris Tricine SDS running buffers and are suitable for use with Cleaver Scientific’s omniPAGE mini vertical electrophoresis and blotting systems....

 

  Compact, Portable Gel Documentation System for Imaging Real-Time Nulceic Acid Gels

A new lightweight, portable gel documentation system which enables  visualisation of real-time size fractionation of nucleic acids has been introduced by electrophoresis specialists CLEAVER SCIENTIFIC LTD (CSL)

CSL-RVGEL Doc2The RunDOC gel documentation system is designed exclusively for use with CSL’s innovative runVIEW system and comprises a darkroom hood and a 10 megapixel digital camera to capture images of nucleic acids gels stained with EtBr, SYBR and runSAFE. RunDOC is designed to be placed directly over the RVMSCHOICE gel tank located on the runVIEW base unit, which includes an ...

 

  New Video Showcases Gel Electrophoresis Systems from Cleaver Scientific

The comprehensive range of CLEAVER SCIENTIFIC (CSL) electrophoresis systems is featured in a new series of videos recently produced to highlight the many features and benefits of these innovative products

GEL ELECTROPHORESIS SYSTEMS videoThe videos include a review of the CSL Multisub range of horizontal systems which are designed for all nucleic acid gel electrophoresis applications and include the choice of models available, such as; MSMIDI, MSCHOICE and MSMINIDUO...

 

  Wave Goodbye to time-consuming Large Format Vertical Gel Electrophoresis

Helping to make life that ‘little bit easier in the Lab’ is one of the objectives that drives Gel Electrophoresis specialists CLEAVER SCIENTIFIC Ltd (CSL) to continually develop new products which save time and space. A good example of this is the new VS20 Wave Maxi System - their latest innovation for large-format vertical gel electrophoresis

The new VS20 Wave Maxi SystemThe VS20 Wave is designed to perform a variety of separations, ranging from first and second dimension SDS-PAGE to capillary tube gel IEF and electroblotting. However, unlike other systems whose traditional clamping configurations require adjustment of as many as 24 screws to secure just two glass plates, the VS20 WAVE insert utilises only four screws to secure as many 20 x 20cm gels. This innovative vertical screw-clamp technology ensures not only much faster set-up speed it also exerts uniform pressure along the height of the glass plates to facilitate a leak-free seal without gel compression and bowing to provide even migration...

 

  New Gene Cloning Tool is a Safer, More Sensitive Option A new, ready-to-use, safe, sensitive and more flexible alternative to ethidium bromide and other DNA stains has been introduced by electrophoresis specialists CLEAVER SCIENTIFIC (CSL). 

Cleaver-AB12RunSafeTM is a significant new tool for gene cloning applications which enables scientists to see their samples separate in real time. RunSafeTM is a non-mutagenic fluorescent reagent that produces instant visualisation of DNA bands upon Blue Light or UV illumination of gels...

 

  New ‘Real Time’ Gene Cloning Tool Saves Time, Space and Money A new, self-contained GENE CLONING SYSTEM which enables real-time fractionation and recovery of nucleic acids in real time has been introduced by electrophoresis specialists CLEAVER SCIENTIFIC (CSL).

cleaver_runVIEWThe RunVIEW system is claimed to be the most innovative and versatile tool for gene cloning for real-time horizontal gel electrophoresis. RunVIEW combines the flexibility and high resolution capability of the MSCHOICE system with the time and space-saving convenience of having the power supply and gel illuminator integrated within one highly compact, bench top unit...

 

  New Electrophoresis and Laboratory Consumables Catalogue Now Available from Cleaver Scientific Cleaver Scientific Catalogue 2012/13Cleaver Scientific Ltd is delighted to announce that their latest product catalogue is now available. Since the company was incorporated, just 8 years ago, the new catalogue has grown to a publication of 96 pages and offers a range of instruments, chemicals and consumables for both electrophoresis and indeed the life science laboratory...

 

  Safe and Effective Protection from Radioactive Compounds Cleaver acrylic radiation shielding productsSafe, effective protection for laboratory personnel is essential where applications and techniques involve either beta or gamma emitting materials, such as the detection of nucleic acids and proteins, or for radioimmunoassay and metabolic studies. To meet this requirement laboratory supply specialists CLEAVER SCIENTIFIC (CSL) offers an extensive range of competitively priced acrylic radiation shielding products, which are manufactured in the UK.  The range includes over 120 products, including shields, boxes, racks, waste bins, spillage trays and cabinets...

 

  Fast, Flexible and Convenient Electrophoresis Cleaver-AB11Saving time, space and minimising effort in the laboratory, yet producing products which contribute toward achieving high quality scientific results, are the main features and benefits of the CLEAVER SCIENTIFIC (CSL) range of electrophoresis products.  The range now includes the compact CSL multiSUB Midi 96 system which can be used in conjunction with samples from 96 well plates to allow direct loading and easy identification of samples...

 

  A convenient ‘Mini Cleanroom’ within your laboratory The CSL UV sterilisation cabinetsA compact and convenient, yet safe, nucleic acid-free environment is one of the main advantages offered by the uvCAB UV Sterilisation Cabinets available from CLEAVER SCIENTIFIC (CSL). Similar to having a ‘mini-cleanroom' within your laboratory these cabinets provide a low-cost, easily accessible area for setting-up PCR (Polymerase Chain Reactions) whilst minimising the potential for PCR reaction contamination...

 

  Organic Agarose is Clever for DNA, Kinder to the Environment CleverGELA new high grade, more environmentally friendly Agarose for Nucleic Acid Electrophoresis techniques has been introduced by laboratory equipment specialists CLEAVER SCIENTIFIC (CSL). CleverGEL is suitable for routine analysis of nucleic acids and is manufactured using an organic, more environmentally friendly solvent-free process...

 

  Mini Centrifuge sets new Standards for Capacity & Flexibility Cleaver-myfugeA Mini Centrifuge, which eliminates the need to change rotors when switching between microtubes and PCR strips and provides twice the capacity of traditional mini centrifuges, has been introduced by CLEAVER SCIENTIFIC (CSL). The multifuge features an innovative duoROTOR design that enables the simultaneous spinning of 12 microtubes and 4 PCR strips which effectively doubles its capacity compared to most conventional mini centrifuges...

 

  Environmentally friendly Mini Drybath fits In the palm of your hand Cleaver microBLOCKA new personal mini drybath, which has the smallest footprint of any dry bath presently available, has been introduced by laboratory equipment specialists CLEAVER SCIENTIFIC (CSL). The microBLOCK is an ultra-compact mini dry bath with a 15 x 10cm footprint, so is not only small enough to fit within the palm of your hand, but is also perfect for use in laboratories where bench space is limited...

 

  All-in-One Electrophoresis Packages Save Time and Money ALL-IN-ONE ELECTROPHORESIS PACKAGESElectrophoresis specialists CLEAVER SCIENTIFIC (CSL) now offer their range of electrophoresis products as all-in-one package deals for optimum economy and convenience. The complete range of these package deals means that CSL provides one of the widest ranges of combination packages to meet the DNA, RNA and protein electrophoresis requirements of today's scientists...

 

  Low Cost Gel Tanks and Classroom Kits Serve Growing Needs of Further Education CLEAVER SCIENTIFIC educational electrophoresis kitsMolecular biology, once only the remit of university life science laboratories, is becoming increasingly important in the curricula of secondary schools, sixth forms and colleges of further education. Electrophoresis, which underpins many molecular biology techniques, including gene cloning, is now explained to students in comprehensive detail by the electrophoresis specialists, CLEAVER SCIENTIFIC (CSL), in their newly launched educational electrophoresis kits.

 

  Cleaver Scientific offers New Range of Fermentation Systems Cleaver Scientific offers New Range of Fermentation SystemsCleaver Scientific now provides versatile high-performance bench top fermentor and bioreactor systems for cell cultivation applications. Each system is offered as a complete package with vessel, impeller, control station and probes for growth of microbial, plant and animal cells.

 

  Buy British For A Greener, More Efficient Laboratory CLEAVER SCIENTIFIC Choosing British designed and manufactured products will always be viewed as a better choice, especially for UK based companies and this certainly applies to the UK laboratory and life science sectors. Furthermore, when the environmental benefits, based on the increasingly important energy-efficiency comparisons are taken into account, the reasons for choosing British products become even more compelling

 

  More Features, at Lower Cost, with Ultra-Compact Gel Documentation System A new, ultra-compact Gel Documentation system, which offers a host of new features, yet is simple and easy-to-use, occupies a very small footprint and is competitively priced, has been introduced by CLEAVER SCIENTIFIC (CSL). The CSL microDOC BASIC is based upon existing microDOC systems and includes many of the features from these successful models.

 

  New Electrophoresis Catalogue from Cleaver Scientific The latest Cleaver Scientific catalogue represents a tremendous fillip for scientific manufacturing within the UK. A three-fold expansion in content over previous editions - with each product being individually showcased on every page - the new Cleaver Scientific catalogue offers everything from precision manufactured gel tanks to chemicals, gel documentation systems, and general laboratory and radiation safety products.

 

  INCUBATORS PROVIDE OPTIMUM CHOICE AND FLEXIBILITY A range of compact, space-saving benchtop incubators which provide excellent choice and flexibility to the laboratory scientist are now available from laboratory supply specialists CLEAVER SCIENTIFIC (CSL). These incubators, or hybridisation units, provide a chamber temperature from ambient to 85ÂșC and are ideal for many laboratory tasks, such as cell and tissue culture applications.

 

  EFFECTIVE PROTECTION FROM RADIOACTIVE COMPOUNDS Where life science research laboratory applications and techniques involve radioactive compounds, safe and effective protection for operatives is an essential requirement. For example, techniques involving either beta or gamma emitting materials used in the detection of nucleic acids and proteins, or others such as radioimmunoassay and metabolic studies.

 

  SMOOTH, VARIABLE SPEED MIXER IS COMPACT & LIGHTWEIGHT Smooth, fast and efficient mixing with minimal vibration across all speeds is an important requirement for many laboratory applications and the new variable speed Vortex Mixer from laboratory equipment specialists CLEAVER SCIENTIFIC is an ideal solution.

 

  COMPACT AND ECONOMICAL DRY BATHS Compact, easy-to-use and offering excellent value for money are among the key features and benefits of the cube digital dry baths available from laboratory equipment specialists CLEAVER SCIENTIFIC (CSL).

 

  ULTRA-COMPACT GEL DOCUMENTATION SYSTEM TICKS ALL THE BOXES The popular CSL MicroDOC ultra-compact and easy-to-use gel documentation system is now available with software and a choice of transilluminators in either 21 x 21cm or 21 x 26cm sizes.

 

  FASTER, EASIER SAMPLING FROM 96-WELL PLATES Saving time and minimising effort in the laboratory, yet producing products which contribute toward high quality results, are the main objectives behind the development of the CLEAVER SCIENTIFIC (CSL) range of electrophoresis products.

 

  FAST, FLEXIBLE AND CONVENIENT ELECTROPHORESIS Saving time and minimising effort in the laboratory, yet producing products which contribute toward high quality results, are the main objectives behind the development of the CLEAVER SCIENTIFIC (CSL) range of electrophoresis products.