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All articles from Anasys Instruments

  UCSB and Getty Conservation Institute Researchers Study Cultural Heritage Painting Cross-Sections Using Breakthrough AFM Based Nanoscale Mass Spectrometry Technique

Anasys Instruments reports on the study of cultural heritage painting cross-sections by researchers from UCSB and the Getty Conservation Institute using their breakthrough AFM-based nanoscale mass spectrometry technique. 

anasys instruments The analysis of cultural heritage materials presents a number of challenges such as: limited and extremely small samples, complexity of sample structure, the importance of maintaining spatial integrity and, most notably, the rarity of the samples. These limitations present specific challenges for the identification of many traditional organic dyes, particularly in paintings that may have multiple original paint layers (depending on the artist’s...


  NIST Researchers Enabled by AFM-IR to Publish first Nanoscale IR Spectra of Individual Plasmonic Nanostructures

Anasys Instruments reports on the new AFM-IR results from the Energy Research Group at NIST just published in the journal for Advanced Optical Materials. The paper is entitled “Nanoscale imaging and spectroscopy of plasmonic modes with the PTIR technique.”

PTIR techniqueResearchers from the NIST Center for Nanoscale Science and Technology (CNST) and the University of Maryland have used photothermal induced resonance (PTIR) to characterize individual plasmonic nanomaterials in order to obtain absorption maps and the first examples of absorption spectra with nanometer-scale resolution. Nanostructuring of plasmonic materials enables engineering of their resonant optical response and creates new opportunities for applications that benefit from...


  University of Manchester Selects Anasys AFM-IR for Coatings and Corrosion Research

Anasys Instruments reports on the recent installation of an AFM-IR system at the Corrosion & Protection Centre, part of the School of Materials at the University of Manchester for use by the group of Professor Stuart Lyon.

john waltonCorrosion is of primary concern in many industrial sectors, including oil, transportation, infrastructure, nuclear, and even bio-technology. At the University of Manchester, the Corrosion and Protection Centre has one of the world’s largest academic bases focused on corrosion and its control. Professor Stuart Lyon is the Director of Research and AkzoNobel Professor of Corrosion Control in the School of Materials. His research interests are...


  EPFL Research on the Use of AFM Based Nanoscale IR Spectroscopy for the Study of Single Amyloid Molecules Wins Poster Competition at Swiss Physics Society Meeting

Anasys Instruments reports on EPFL’s Francesco Simone Ruggeri success winning a poster award at the recent annual meeting of the Swiss Physics Society held at the University of Fribourg. 

anasysFrancesco Simone Ruggeri is a member of the Doctoral Program in the group of Professor Giovanni Dietler, head of the Laboratory of the Physics of Living Matter at the École Polytechnique Fédérale de Lausanne (EPFL). The research activity of the laboratory of physics of living matter is mainly devoted to the study of DNA topology, cellular machines, protein mechanics and high-resolution low temperature Atomic Force Microscopy (AFM)...


  EPFL Scientists Use Nanoscale IR Sectroscopy to Demonstrate ? to ? Secondary Structure Transition Associated with Amyloid Formation

Anasys Instruments reports on EPFL’s latest research on lysozyme droplets and α-synuclein macromolecular aggregates illustrating application of the nanoscale AFM-IR technique to demonstrate α to β secondary structure transition associated with amyloid formation. 

anasys instruments nanoProteins aggregating into amyloid structures are involved in important neurodegenerative disorders such as Alzheimer’s and Parkinson’s disease. During aggregation, initially monomeric proteins undergo internal structural rearrangement forming amyloid fibrils with a universal cross β -sheet quaternary structure. During fibrillation, several coexisting amyloidogenic species are formed and the study of these species would allow...


  New NIST Publication on AFM-IR has Implications for Catalysis Research

Anasys Instruments reports on a new publication from their nanoIR users at NIST which assess the chemical composition of a metal-organic framework with nanoscale resolution. The publication may be accessed in the leading journal “Angewandte Chemie International Edition.”

anasys instruments

Researchers from the NIST Center for Nanoscale Science and Technology (CNST), in collaboration with researchers from University of Lyon, France, have applied a novel microscopy technique to characterize metal-organic framework (MOF) materials, potentially opening a pathway for engineering the chemical properties of these materials at the nanoscale.* MOFs are composed of metal ions connected by organic linker molecules to form 3D-crystalline networks of nanopores with....


  Inventor of AFM-IR technique to receive the prestigious Ernst Abbe Memorial Award for pioneering field of nanoscale IR Spectroscopy

Anasys Instruments is pleased to announce that the inventor of the AFM-IR technique, Professor Alexandre Dazzi from the Université Paris-Sud, is to receive the Ernst Abbe Memorial Award.

Nanoscale IR System 2The award is given by the New York Microscopy Society and will be presented at the 2014 Eastern Analytical Symposium and Exhibition being held November 17-19, Somerset, New Jersey, USA. Professor Alexandre Dazzi, from the Laboratoire de Chimie Physique at the Université Paris-Sud has been selected to receive the New York Microscopy Society’s Ernst Abbe Award. Since its inception in 1973, 24 scientists have been recognized including innovators such as Albert V. Crewe (inventor of Scanning Electron Transmission Microscopy), Edwin H. Land (inventor of Polaroid photography), Gerd Binning & Heinrich Rohrer (inventors of AFM)...


  AFM-IR used by French researchers to identify best microbes for biofuel production

Anasys Instruments reports on the publication in the Journal of Physical Chemistry Letters demonstrating the use of AFM-IR used by French researchers to identify best microbes for biofuel production.

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While the debate over using crops for fuel continues, scientists are now reporting a new, fast approach to develop biofuel in a way that doesn't require removing valuable farmland from the food production chain. Their work examining the fuel-producing potential of Streptomyces, a soil bacterium known for making antibiotics, appears in ACS' The Journal of Physical Chemistry Letters (see footnote). The scientists used atomic force microscopy combined with infrared spectroscopy (AFM-IR) to measure the size and map the distribution of oil inclusions inside of microorganism without staining or other special sample preparation...



Anasys Instruments reports on EPFL's publication in Plant Cell on the use of nanoIR to look into the process of photosynthesis to shed more light on how plants produce energy

The Anasys nanoIR system of Andrzej Kulik from Giovanni Dietler's group at EPFLÉcole Polytechnique Federale de Lausanne, better known as EPFL, has recently reported on how a group of its scientists have used powerful imaging techniques including nanoIR to support a study which sheds light on photosynthesis. All plants use a form of photosynthesis to produce energy, though not all rely exclusively on it. In higher plants, capturing light takes place in specialized compartments called thylakoids. These are found in cell organelles called chloroplasts, which are the equivalent of a power station for the plant....


  Anasys Instruments unveils the nanoIR2 - the second generation AFM based IR spectroscopy platform, incorporating top-side illumination

Anasys Instruments announces the release of the nanoIR2™, the second generation of AFM-based IR spectroscopy.

The new nanoIR2 AFM based IR spectrometer system from Anasys Instruments Anasys Instruments is proud to announce the nanoIR2™, a second generation AFM based IR spectroscopy (AFM-IR) platform. A key breakthrough is the ability of the nanoIR2 to operate with top-side illumination, eliminating the prior need to prepare samples on a ZnSe prism and enabling measurements on a much more diverse set of samples. AFM-IR measurements have now been demonstrated....


  Anasys users publish new peer-reviewed research papers using nanoIR.

Anasys Instruments reports on three user groups who have published peer reviewed papers where nanoIR is being applied to look at characterization challenges in semiconductors, polymers and healthcare.

A scanning AFM tip detects the expansion of the underlying material in response to absorption of infrared light.

There have been several recent exciting publications by nanoIR users in a number of growing applications areas. These include plasmonics, health care, fuel cell membranes and polymer nanostructures. Three of these publications are reported here. Nanoscale Imaging of Plasmonic Hot Spots and Dark Modes with the Photothermal-Induced Resonance Technique. The lead author is Dr Andrea Centrone from NIST, USA. In this publication from NIST, the AFM-IR technique is applied for the first time to image the dark plasmonic resonance of gold asymmetric split ring resonators (A-SRRs) in the mid-infrared (IR) spectral region with nanoscale resolution...



Anasys Instruments announces a new application for AFM-IR to study as reported by research scientists in NIST publication "Tech Beat."

A scanning AFM tip detects the expansion of the underlying material in response to absorption of infrared lightResearchers from the National Institute of Standards and Technology (NIST) and the University of Maryland have shown how to make nanoscale measurements of critical properties of plasmonic nanomaterials—the specially engineered nanostructures that modify the interaction of light and matter for a variety of applications, including sensors, cloaking (invisibility), photovoltaics and therapeutics. Their technique is one of the few that allows researchers to make actual physical measurements of these materials at the nanoscale without affecting the nanomaterial's function...


  Anasys reports on University of Illinois study of near-field behavior of semiconductor plasmonic microparticles using AFM-IR published in APL

Anasys Instruments reports on the announcement from the University of Illinois which describes the effect of nanometer-scale heating on semiconductor plasmonic microparticles which reveal surface plasmon resonance. The work is described in a paper published in Applied Physics Letters.

An atomic force microscope image of plasmonic semiconductor microparticlesRecent progress in the engineering of plasmonic structures has enabled new kinds of nanometer-scale optoelectronic devices as well as high-resolution optical sensing. But until now, there has been a lack of tools for measuring nanometer-scale behavior in plasmonic structures which are needed to understand device performance and to confirm theoretical models...


  New University of Illinois publication on nanoscale chemical analysis using AFM-IR

Anasys Instruments reports on the recent publication from the University of Illinois which describes the development of a novel technique for chemical identification at the nanometer scale based on AFM-IR. The work is described in a paper published in the Review of Scientific Instruments 84.

AFM-IR is a product from Anasys Instruments

For more than 20 years, researchers have been using atomic force microscopy (AFM) to measure and characterize materials at the nanometer scale. However AFM-based measurements of chemistry and chemical properties of materials were generally not possible, until now...


  Anasys report on EPFL researchers applying AFM-based infrared spectroscopy to the study of drug resistant bacteria

Dr Andrzej Kulik is a research associate in the Laboratory of the Physics of Living Matter at the EPFL in Switzerland.

Experienced microsopist Dr Sunny Jeong from EPFL using the Anasys nano-IRUnder the leadership of Professor Giovanni Dietler, the research activity of the laboratory of physics of living matter is mainly devoted to the study of DNA topology, cellular machines, protein mechanics and high-resolution low temperature Atomic Force Microscopy (AFM). Through internal and external collaborations, a certain number of other research activities are carried out in particular on knots hydrodynamics, DNA gel electrophoresis, cell elasticity, cell motility, etc. Kulik and his colleagues are measuring the mechanical properties of proteins, cells and tissues. To date, AFM has been the main tool but is now complemented with the arrival of a nanoIR™ AFM-IR system from Anasys...


  Anasys report on the Lorentz Contact Resonance imaging mode now available for their afm+ and nanoIR systems

Anasys Instruments continues to expand the capabilities of their nanoscale materials characterization techniques with the Lorentz Contact Resonance (LCR) imaging mode. This is now available for their afm+® and nanoIR™ systems

Schematic to illustrate Lorentz Contact Resonance imagingThe Lorentz Contact Resonance imaging mode further enhances the capabilities of the afm+ and nanoIR systems from Anasys. LCR allows rapid broadband nanomechanical measurements over a range of temperatures. LCR imaging differentiates between multiple components of a sample and allows precise location of the probe for subsequent chemical or thermal analysis with nanoscale resolution...


  Anasys to discuss major improvements to its AFM-IR nanoscale spectroscopy product family at Pittcon 2013

The rapid introduction of nanostructured materials continues to drive nanoscale characterization techniques to provide timely, accurate, easy to use analysis methods. Anasys designs breakthrough, award-winning products that measure nanoscale material properties while providing high quality AFM imaging

Kevin KjollerThis family of instrumentation includes the nano-TA™ which provides nanoscale thermal property measurements and the nanoIR™ platform which has pushed the barriers of the field of nanoscale IR measurement to new levels of resolution. User-feedback has led to a number of new capabilities being added to systems bringing greater benefit in terms of resolution and instrument performance...


  Researchers from the University of East Anglia, UK, use nanoscale thermal analysis techniques to improve drug delivery systems

Anasys Instruments report on the use of their award-winning nanoscale characterization instrumentation to advance developments in the understanding of drug delivery systems

Dr Jonathan Moffat

The Drug Delivery & Materials Characterization Group at the University of East Anglia, UK, is internationally recognized for work involving the development of novel thermal, dielectric, rheological and microscopic techniques as analytical tools within the pharmaceutical sciences. There is particular emphasis on the study of the physical properties of drugs and dosage forms in relation to performance...


  NIST research highlights promise of AFM-IR for quantitative nanoscale chemical analysis

Anasys Instruments announces a new paper authored by Dr Andrea Centrone and his colleagues at NIST published recently in Small, a leading publication which focuses on the nano and micro worlds

Schematic to show the operation of AFM-IRDr Centrone's team reported on experiments that carefully studied the AFM-IR signal strength versus sample thickness. The experiments showed that the AFM-IR signal increases linearly with thickness for samples up to 1µm thick. This observed linearity may pave the way for quantitative chemical analysis at the nanoscale...


  Reverse Engineering of polymers using nanoscale IR spectroscopy via AFM-IR A recent publication in Spectroscopy Europe by lead authors from Kimberly Clark Corporation showed the use of AFM based nanoscale IR Spectroscopy for reverse engineering of polymeric multilayer films.

AnasysThe Atomic Force Microscope (AFM) is a fairly common nanoscale characterization technique but its main drawback to date was its inability to provide chemical composition information from a sample. By combining the AFM with a tunable Infrared (IR) source, IR spectra with nanoscale spatial resolution can be collected. As film thicknesses in multilayer films continue to shrink, AFM-IR provides an important capability for sample analysis...


  Purdue University researchers use nanoscale IR spectroscopy via AFM-IR to provide key insights into drug-polymer blends AnasysTwo new papers are going to press featuring the use of Anasys Instruments' nanoIRTM system by Professor Lynne S. Taylor's group in the Department of Industrial and Physical Pharmacy at Purdue University. In each study, miscibility of pharmaceutically relevant blends was examined and specific sub-micrometer-sized domains characterized using standard atomic force microscopy (AFM) and nanoscale Infrared spectroscopy (AFM-IR)...


  nanoTA nanoscale Thermal Analysis for Cure Rate and Cross Link Density determination receives 2011 Best Paper Award from SPE ANTEC Anasys InstrumentsAnasys Instruments has been chosen to receive a Best Paper Award for 2011 for a talk given at ANTEC 2011. The paper, titled "Rapid Determination of Cure Rate and Direct Identification of Spatial Variations in Cross Link Density", was presented at the Polymer Analysis: Advances in Analytical Characterization: Hyphenated and New Techniques Division session during the ANTEC conference at the beginning of May this past year. On behalf of Anasys, Roshan Shetty will receive the award at ANTEC 2012...


  Anasys adds arbitrary polarization control to the nanoIR, the nanoscale IR spectroscopy system AFM-IRAnasys Instruments, the company that pioneered nanoscale thermal analysis and nanoscale IR spectroscopy using an AFM, is pleased to announce further capabilities for their nanoIR nanoscale infrared spectroscopy system. The availability of arbitrary polarization control enables the user to measure and visualize molecular orientation with nanoscale spatial resolution. This is useful in a variety of applications where the understanding molecular orientation is important. One of the most exciting applications is the study of polymeric fibers where molecular orientation is vital to controlling their properties...


  Invited award symposium presentation on molecular orientation of electrospun fibers using nanoscale IR spectroscopy at Pittcon 2012 Anasys InstrumentsAnasys Instruments, the company that pioneered nanoscale thermal analysis and nanoscale IR spectroscopy using an AFM, is pleased to announce that Dr. Bruce Chase is presenting an invited talk entitled "Structure and Orientation in Electrospun Nanofibers" at the 2012 Pittsburgh Conference, as part of the Organized Contributed Session on Analytical Applications of Broadly Tunable Lasers. The presentation will include spatially resolved measurements of molecular orientation obtained by a technique combining atomic force microscopy and infrared spectroscopy (AFM-IR)...


  New AFM platform from Anasys for analytical measurements afm+, the new AFM platform from AnasysAnasys Instruments, the company that pioneered nanoscale thermal analysis and nanoscale IR spectroscopy using an AFM, has chosen the Fall 2011 MRS meeting to introduce a brand new, easy-to-use research and analysis tool. The afm+ is the first fully integrated AFM platform to offer three important analytical capabilities...


  Leading researchers publish keynote paper applying AFM-IR to better understand polymer crystallization processes on the sub-micron length scale The Anasys AFM-IR systemAnasys Instruments' AFM-IR system is featured in a new keynote publication in this month's issue of Applied Spectroscopy: Spatial Differentiation of Sub-Micrometer domains in a Poly(hydroxyalkanoate) copolymer using instrumentation that combines Atomic Force Microscopy (AFM) and Infrared (IR) Spectroscopy...


  Anasys Instruments receives Microscopy Today Anasys AFM-IR system Anasys Instruments' AFM-IR system has been recognized by Microscopy Today in the receipt of the 2011 Innovation Award. It was presented to CEO, Roshan Shetty, at the 2011 M&M Annual conference held this year in Nashville, TN. The AFM-IR technique was developed by Dr. Alexandre Dazzi at the University of Paris-Sud. It uses an AFM probe as the IR absorbance detector and hence obtains IR spectroscopy at up to 2 orders of magnitude better than traditional IR spectroscopy...


  Top journal announces highlighted Schematic representation of AFM-IR Anasys Instruments is pleased to report the publication and highlighting of a "hot paper" from a group of leading French scientists in the leading scientific journal, Angewandte Chemie. The paper address a molecular mapping challenge using the exciting technique of AFM-IR, the combination of an atomic force microscope (AFM) and IR spectroscopy...


  Anasys scientific co-founder appointed to prestigious professorship in the College of Engineering at the University of Illinois, Urbana-Champaign William P King, newly appointed Bliss Professor of Engineering at the University of IllinoisAnasys Instruments is pleased to announce that Dr William P King has been appointed as the Bliss Professor of Engineering at the University of Illinois at Urbana-Champaign. In addition to his faculty position at UIUC, Dr. King serves as a key scientific advisor to Anasys Instruments...


  Breakthrough Nanoscale Infrared Spectroscopy Technology Anasys Instruments is pleased to announce that their nanoIRTM platform, a powerful new measurement tool that reveals the chemical composition of samples at the nanoscale, has been selected to receive a prestigious R&D 100 Award.


  Anasys Instruments Unveils Breakthrough Nanoscale Infrared Spectroscopy Technology Anasys Instruments is pleased to introduce its highly innovative nanoIRTM platform, a powerful new measurement tool that reveals the chemical composition of samples at the nanoscale.



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