Market leader in temperature and environmental-controlled microscopy, Linkam Scientific Instruments, presented its cryo-correlative systems – the CMS196 and the CryoGenium plunger – at this year’s Microscopy and Microanalysis conference (M&M).

Linkam showcased a range of temperature-controlled stages at this year’s M&M, with a focus on its cryo-correlative portfolio, and hosted live tutorials on system operation and performance. Linkam also be presented a poster at the event.

The CMS196 is a cryo-correlative stage which can be used for the correlation of biochemical processes within cells. Providing high-resolution structural information from electron microscopy (EM) images, it can be interfaced with a variety of upright microscopes and is an integral part of a correlative light and electron microscopy (CLEM) workflow. The system also supports reduced sample contamination, improved sample handling, and enhanced stability for super-resolution cryo imaging.

Also at the booth will be the Linkam CryoGenium, one of the company’s newest developments in electron microscopy (EM) grid vitrification. The system aims to address problems faced by users using Cryo-EM, cryo-tomography, single particle tomography (SPT) and cryo-CLEM, as the novel design replaces the common blotting mechanism to improve process stability and repeatability. This is done through the system’s patented suction method, with optical monitoring to adjust the sample thickness in a controllable manner.

Clara Ko, Sales and Marketing Manager at Linkam, comments: “We are excited to be back at M&M this year, demonstrating how we can support scientists who are conducting research at sub-zero temperatures. The CMS196 stage is one of our best-selling systems, and we’re looking forward to being able to showcase this alongside our new CryoGenium plunging system. Our live demonstrations allow delegates to see the systems in action, and provides them with an opportunity to speak to our specialists at the booth.”

About Linkam Scientific Instruments 

Linkam develops and manufactures a broad range of temperature and environmental control stages for both OEMs and end users. From high to cryo temperatures as well as humidity, electrical connections, gas purging, vacuum and pressure, for enhanced sample analysis. Linkam stages are used with light microscopes and a wide range of analytical techniques including Raman, FTIR, SAXS-WAXS and many more to visualise and characterise the properties of materials. Linkam stages are found in thousands of laboratories worldwide with the most successful microscope heating stage, the THMS600, selling over 6,000 units alone. Linkam is the market leader in temperature-controlled microscopy.  

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