New Insights Published on Key Protein Interactions Involved in the Bacterial Flagellar Motor Complex Show Promise for Other Difficult Biomolecular Systems

New Application Note from Wyatt Technology Showcases the Ability of CG-MALS to Quantify Complex Proteins. Wyatt Technology Corporation, the world leader in absolute macromolecular characterization instrumentation and software, has today published a new application note highlighting a study on the complex interactions between proteins and how they modulate the rotational direction of bacteria flagella....

The Innovation Forum is launching their first annual Innovation Leaders Conference to be held at Cambridge University, UK on February 27th and 28th 2014.

The aim of the conference is to promote the translation of cutting edge research into leading products and services – by building bridges between academia, investors, industry and government and linking innovative minds across disciplines. The event is being supported by leading recruitment specialists - george james ltd who have arranged for leading industry experts across a broad range of disciplines to be available to give free advice to both start up and established companies and individuals looking for careers advice...

Thermo Fisher Scientific is pleased to announce a new technical note which demonstrates high resolution chromatographic separations of organic acids in beer samples.

Organic acids are end products of yeast fermentation critical to the flavor of beer, but are also products of bacterial fermentation that introduce a sour flavor, either purposely or unintentionally due to spoilage. Technical Note 126: Determination of Organic Acids in Beer Samples Using a High-Pressure Ion Chromatography System specifically discusses the separation of organic acids in beer samples using a Thermo Scientific™ Dionex™ IonPac™ AS11-HC-4μm anion-exchange column....

VICI Metronics’ Dynacalibrator® Model 150  is a constant temperature system designed to generate precise ppm or ppb concentrations of chemical compounds in a gas stream, using permeation devices as the trace gas source.

It is used as a reference for the calibration of gas chromatography instruments and in other instruments that measure gas concentrations. This light-weight unit is a compact calibrator capable of delivering the precise concentrations required. A passivated Inertium® coated stainless steel permeation chamber houses the permeation device(s), with measured inert carrier gas sweeping the calibration gas/vapor from the chamber.....

Dates and Agenda Set, Registration Now Open for Quantitative Proteomics and ProteoMMX 3.0 Events

Waters Corporation (NYSE:WAT) and the Biochemical Society announced today the opening of registration for the Biochemical Society’s Quantitative Proteomics Training Day and the ProteoMMX 3.0 Symposium, consecutive events taking place March 24 - 27, 2014 in Chester, England. The Quantitative Proteomics Training Day is aimed at researchers seeking to gain familiarity with the field of quantitative proteomics. ProteoMMX 3.0, following immediately after the Training Day, is dedicated to current thinking and state of the art research in quantitative proteomics...

Microbiology specialist Lab M is exhibiting for the first time at this year’s Arab Health exhibition and congress.

The company will take this opportunity to introduce visitors to its comprehensive portfolio of dehydrated culture media (DCM) as well as the recently launched µPREP™ line of ready-to-reconstitute bagged media  and an extended range of Captivate™ immunomagnetic separation products.“Demand for Lab M products, especially our DCM products that are used both by those working in labs and by commercial plate pourers, continues to grow in the countries that the Arab Health event serves and we are looking to extend our representation in the region....

Malvern Instruments brings a new addition to Pittcon in 2014, exhibiting NanoSight Nanoparticle Tracking Analysis (NTA) systems within its growing portfolio of analytical solutions for industry and academia.

Pittcon 2014 is Malvern’s first major exposition in the US since acquiring NanoSight in September 2013, a move which resulted in the addition of NTA to Malvern’s technologies for particle sizing and counting at the nanoscale. NTA systems will be on show alongside the Zetasizer Nano and the new Viscotek SEC-MALS 20 GPC/SEC detector.  Also on the Malvern booth is the Mastersizer 3000 laser diffraction particle size analyzer featuring new software....

Malvern Instruments has posted a new application note demonstrating the use of the company’s Viscotek SEC-MALS 20 multi angle light scattering (MALS) detector for size exclusion chromatography (SEC) in the analysis of monoclonal antibodies.

The application note, ‘Molecular weight measurements of an antibody using Viscotek SEC-MALS 20’, reports experimental data for the analysis of aggregates within monoclonal antibody formulations and can be freely downloaded. Monoclonal antibodies are being targeted for use in a growing range of therapeutic applications. Measuring the molecular weight of the protein, monomer, oligomers and aggregates within the sample and in formulations is an important part of assessing their safety and efficacy as drugs.....

Photoactivated localization microscopy (PALM) in 3D with ZEISS ELYRA

Expanding its 3D microcopy portfolio, ZEISS is introducing superresolution photoactivated localization microscopy (PALM) in 3D at the Society for Neuroscience Annual Meeting in San Diego, California. With a new module, ELYRA P.1 now enables superresolution photoactivated localization microscopy (PALM) in 3D for endogenously-expressed photo-switchable fluorescent proteins. Users can capture highly resolved structures in 3D, while treating the sample so gently it stays fit for long-term observation...

Dynaflow^® Resolve Temperature Control combines controlled solution exchange with precise temperature regulation

Cellectricon, a leading provider of advanced cell-based screening technologies and services, launches the Dynaflow^® Resolve Temperature Control system at Neuroscience 2013 (San Diego), booth #933. Cellectricon’s Dynaflow Resolve automated perfusion system uses microfluidics for rapid and efficient solution exchange experiments, enabling the measurement of ion channel current regardless of cell type or compound. The new Temperature Control add-on module has been specifically developed to enable high performance patch clamp experiments at physiological temperatures, from room temperature up to 45 °C...

OGT provides insight on NGS enrichment optimisation

Oxford Gene Technology (OGT), provider of innovative genetics research and biomarker solutions to advance molecular medicine, has produced a free whitepaper titled ‘The importance of enrichment assay choice and optimisation for confident variant detection.’ The paper investigates the main strategies employed to optimise target enrichment for next generation sequencing (NGS) assays, assisting researchers to make informed decisions when designing studies...

A new application note from Malvern Instruments explores the role of particle size and the importance of particle size measurement in optimizing the formulation of drilling muds used in oil extraction processes.

Thermo Fisher Scientific has developed a reliable method for determining levels of dithiocarbamate fungicides (DTCs) with high precision using gas chromatography-mass spectrometry (GC-MS).

The complex extraction and identification of DTCs is performed on various food samples after a thorough method validation. Application Note 10333, Analysis of Dithocarbamate Pesticides by GC-MS, compares DTC levels in various food samples to matrix-matched calibration standards. SIM mode analysis provides high selectivity with easy-to-integrate chromatograms. The analysis uses a Thermo Scientific™ TRACE GC Ultra™ gas chromatograph equipped with a Thermo Scientific™ TriPlus™ RSH liquid autosampler coupled to a Thermo Scientific™ ITQ™ 900 ion trap mass spectrometer...

Updated Clinical Chemistry and Toxicology Document on Measurement Procedures for the Determination of Lead Concentrations in Blood and Urine

The Clinical and Laboratory Standards Institute (CLSI) has published a new version of C40-A2—Measurement Procedures for the Determination of Lead Concentrations in Blood and Urine; Approved Guideline—Second Edition. C40-A2 is intended for members of the clinical laboratory testing community involved in the collection and measurement of lead in blood and urine. C40-A2 provides direction for specimen collection, measurement by graphite furnace atomic absorption spectrometry, anodic stripping voltammetry, and inductively coupled plasma mass spectrometry. It includes guidelines for quality assurance and quality control, as well as information on proficiency testing programs and laboratory certification. This edition of the document addresses the clinical significance of lead concentrations < 10 μg/dL (0.48 μmol/L)...

The launch of Malvern Instruments’ Viscotek SEC-MALS 20 chromatography detector has triggered record downloads of one of the supporting white papers ‘Static light scattering technologies for GPC/SEC explained’, underlining the enthusiasm amongst users for straightforward information on GPC/SEC analysis.

The recent addition of Viscotek SEC-MALS 20 to Malvern’s range of detectors puts the company in the unique position of being the sole provider of every commercially available light scattering technology for GPC/SEC. Customers can therefore be assured of a truly unbiased choice of detector solutions. The popular white paper is just one of a suite of educational information and application notes provided by Malvern’s specialist team to help users select the right detector for their application...

Malvern Instruments has recently released an article detailing the use of laser diffraction particle size analysis  for powder metallurgy applications.

Entitled ‘Using laser diffraction to measure particle size distributions’, the article presents new data on how laboratory and on-line laser diffraction provide the comprehensive particle size and size distribution data required to support metal powder product and manufacturing process development. Powder metallurgy - the production of a solid object from the sintering of a fine metal powder - is a versatile and precise method for creating a wide range of metal components.....

XEI Scientific Inc, manufacturer of the popular EVACTRON^® De-Contaminator™ Plasma Cleaning System for electron microscopes and other vacuum chambers, is pleased to announce the publication of a paper in collaboration with General Electric's Global Research Center on the use of in-situ plasma cleaning.

The paper appears in the Journal of Vacuum Science & Technology. A contamination, even at extremely low levels, can often hide or distort analyses of surfaces that researchers would like to study. Such is the case of many of the samples analysed at General Electric's Global Research Center in New York. Attempts to study "as received" samples by time of flight secondary ion mass spectrometry (ToF-SIMS) reveal a contamination signature that has come from processing, handling and/or a specific exposure...

Improved drug delivery and compound identification with the Cellaxess technology

Cellectricon, a leading provider of advanced cell-based screening technologies and services, presented new data at Neuroscience 2013. In a series of poster presentations, Cellectricon demonstrated how its technology can be applied effectively for drug discovery, particularly in relation to cytoskeletal disorders and neurodegenerative diseases.

Pharmig Annual Microbiology Conference covers pharmaceuticals and medical devices

Cherwell Laboratories, specialist suppliers of environmental monitoring and process validation solutions, will once again be supporting Pharmig’s Annual Microbiology Conference at The Oxford Belfry Hotel, Thame. The annual conference, to be held on 20^th & 21^st November, provides the opportunity for individuals to keep up-to-date with the latest hot topics in microbiology. This year the Pharmig conference has presentations and discussions on regulation, investigation, best practice and risk management for microbiology, covering sterile and non-sterile pharmaceuticals and medical devices...

Forensics Europe Expo 29-30 April 2014, is the only dedicated international forum for the entire forensics sector and supply chain to source forensic products, equipment and services, as well as providing the definitive source of education, best practice, training and networking.

Anasys Instruments reports on EPFL's publication in Plant Cell on the use of nanoIR to look into the process of photosynthesis to shed more light on how plants produce energy

École Polytechnique Federale de Lausanne, better known as EPFL, has recently reported on how a group of its scientists have used powerful imaging techniques including nanoIR to support a study which sheds light on photosynthesis. All plants use a form of photosynthesis to produce energy, though not all rely exclusively on it. In higher plants, capturing light takes place in specialized compartments called thylakoids. These are found in cell organelles called chloroplasts, which are the equivalent of a power station for the plant....

Lab Innovations - the UK’s only show dedicated to the latest laboratory technology & consumables, analytical & biotech equipment – which took place last week at the NEC, Birmingham, was a huge success.