Recent Articles in Laboratory Exhibitions and Conferences
Preheating of mobile phases - "nice-to-have" or "need-to-have"?Dec 30, 2009
Controlling the temperature of a column is a prerequisite for reproducible results in HPLC. Column ovens are part of most HPLC systems and many of them offer space even for semi preparative columns. But with increasing inner diameter the heat transfer from the air surrounding the column to the whole cross section of the column (filled with the cold mobile phase) becomes more and more difficult. This may result in bad peak shapes, as the radial temperature gradientcauses different separation conditions for every part of the sample depending on its distance to the outer diameter.
Read MoreHPLC-Tip: Degassing of the mobile phaseDec 30, 2009
A released gas in mobile phases during analysis causes noisy baselines and pressure fluctuations which affect sensitivity and reproducibility. It also severely compromises the use of fluorescence-, refractive-index- or UV-detectors (particularly at wavelengths below 210 nm). As a consequence effective mobile phase degassing must be employed for many analyses.
Read MoreUltra Fast LC for Peptide mappingDec 29, 2009
In order to succeed in developing protein-based drugs, a fast and easy detection of alteration within the protein structure is necessary. In many cases, peptide mapping is the method of choice, where proteins are analysed after digestion.
Read MoreFast routine analysis of alkaloidsDec 29, 2009
The method transfer from a conventional column to an ultra fast analysis for alkaloids has shown that the use of YMC-UltraHT 2 µm column and adjustment of flow parameters for the smaller column dimensions can reduce the analyses time by about 85% accompany with significant solvent savings and significant solvent savings whilst increasing the sample throughput in the laboratory.
Read MoreHPLC hint: The advantage of premixed solvents in HPLCDec 29, 2009
For several reasons the storage of 100% pure solvents in the reservoir bottles of an HPLC system can be a problem. Pure acetonitrile, in particular, affects the system by adsorption of polymers from transmission lines resulting in sticky surfaces that inhibit the opening and closing of the valves
Read MoreSimultaneous separation of pesticides by LC/MSDec 29, 2009
With the constantly rising population and frequent uncertain weather, the need for high yielding agriculture is paramount. This means that use of plant protection agents, such as herbicides and insecticides is necessary, in order to secure harvests.
Read MoreNormal Phase Chromatography Dec 28, 2009
Normal phase chromatography is not very popular with most analytical HPLC users. Poor reproducebility of the results is often cited as an argument against normal phase chromatography.
Read MoreFastLC Application for CurcuminDec 28, 2009
The plant pigment curcumin, found in the popular Indian curry spice turmeric, is well known as an antioxidant for foods. However, researches have paid attention to another characteristic. Curcumin is highly active against the growth of certain cancers.
Read MoreMelamine in pet-foodDec 23, 2009
Melamine (sometimes confused with the plant and animal compound, melanine or another compound, melanin) is an industrial chemical used in the manufacture of plastic products. Despite that, tests showed that a number of milk companies have used it in processing milk to artificially increase the apparent protein content by addition of non-protein nitrogen and so allowing illegal dilution of the product with water with a corresponding increase in sales value.
Read MoreDetection of Mycotoxins in NutsDec 21, 2009
Mykotoxins are natural metabolism products of molds which have a toxic effect on humans and animals. Just like micro-organisms which generate antibiotics, molds which generate mycotoxins have spread all over the world. Aflatoxins are the most toxic form of mycotoxins. Some types of food show an increased risk of aflatoxin release due to fungal infestation: dried fruit, spices, nuts (peanuts, hazelnuts, pistachios) and grain (wheat, corn).
In many pilot-plant or production facilities temperature control systems are like a wallflower at the junior high school dance – they are not the most technical, expensive or exciting equipment in the room and are easily overlooked. But, when the most popular person in the class asks the wallflower to dance...
Read MoreMycotoxins in NutsDec 11, 2009
Every year during the pre- holiday activities the use of nuts increases in order to prepare for the holiday baking. To a large degree unnoticed by consumers is the problem of a possible contamination of these foods with mycotoxins.
Read MoreParticle sizing with static laser scatteringDec 11, 2009
When determining particle sizes a wide variety of techniques are used in which sieving may be the most popular. Sieving is a relatively simple technique, despite the fact that of course different instrumental approaches can be used. The main advantages of sieving are the low price of the instrumentation and the fact that different fractions of the original sample can be prepared for further use.
Read MoreDionex Application Demonstrates a More Efficient and Precise Determination of Steviol Glycosides in Consumer SweetenersDec 11, 2009
Dionex announces a new method for determination of steviol glycosides in consumer sweeteners, which is precise, accurate, and more efficient compared to existing methods (USP and JECFA monographs).
Read MorePittcon Launches Online Scientific CommunityDec 10, 2009
Pittsburgh, PA, December 10, 2009 - Pittcon is pleased to announce the launch of Pittconnect, its new online scientific community. Pittconnect.com was created to provide an online resource for scientists from all over the world to connect with each other to discuss problems, techniques, research, etc
Read MoreUnique Component of the Pittcon Technical Program The 21st James L. Waters Annual SymposiumNov 21, 2009
Pittcon 2010 is pleased to annouce the highlights of the 21st James L. Waters Annual Symposium, which is a unique component of the Pittcon Technical Program.
Read MorePittcon Recognizes Scientists from Academia & Industry Nov 12, 2009
Pittcon is pleased to announce the recipients of ten prestigious awards recognizing the significant contributions of leaders in the fields of Analytical Chemistry and Applied Spectroscopy.
Read MoreTrace-level aliphatic amines in pharmaceutical ingredientsNov 6, 2009
The determination of aliphatic amines in interfering matrices is a challenging task because protonated amines are often poorly retained on the column. This problem is met by applying ion chromatography using coupled-column matrix elimination.
Read MoreIon chromatographic analysis of carbohydrates in essential and non-essential foodstuffsNov 5, 2009
This article describes a straightforward ion chromatographic method that uses isocratic elution and pulsed amperometric detection (PAD) to sensitively determine water-soluble polyols and sugar alcohols as well as mono-, di- and oligosaccharides in essential and non-essential foodstuffs. While carbohydrate determination of most foodstuffs requires only minimal sample pretreatment such as dilution and filtration, samples with interfering matrices such as protein-containing dairy products have to be dialyzed prior to injection.
Read MoreEconomical monitoring of uranium in drinking waterNov 5, 2009
Compared to ICP-MS, determining ultra-trace levels of uranium in drinking and mineral water by adsorptive cathodic stripping voltammetry (AdCSV) is a straightforward, much less expensive alternative allowing measurements with superior sensitivity
Read MorePittcon Announces 2010 Technical Program Nov 3, 2009
The Pittcon Program Committee is pleased to announce that the 2010 Technical Program listing of sessions is now available on the Pittcon website. The Technical Program which begins Sunday, February 28 and closes on Thursday, March 4, 2010, will consist of 62 Symposia, 28 Organized Contributed Sessions, 120 Oral Sessions, 8 Workshops, 45 Conferee Networking Sessions, and 88 Poster Sessions. Read MoreMono Trap A New Generation Tool Adsorption & ExtractionOct 30, 2009
MonoTrapTM is a state-of-the-art silica monolithic and hybrid adsorbent having a large surface area and properties based on silica, activated carbon and Octadecyl functional group.
MonoTrapTM can be used for the simple enrichment analyses and screening of aroma components, foods and environment
