The European Society for Translational Medicine (EUSTM) is a global non-profit neutral platform for the advancement and progress of Translational Medicine.
Translational medicine has gained significant attention from academia, funding bodies, health care policy makers as well as pharma and biotech industry due to its promise to enhance overall quality of global health care. The society's goal is to facilitate research and development of novel and affordable diagnostic tools and treatments for clinical disorders affecting global population...
Nanotechnology conference secures new backers for next year’s event
Nano London 2014, a conference and exhibition for the international nanotechnology industry, is heading confidently towards next year’s event after securing further investment and adding to its list of key industry partnerships. The conference will assemble the leading thinkers and players in the nanotechnology field, and serve as a platform for education, communication, collaboration and innovation...
Oxford Gene Technology (OGT), provider of innovative genetics research and biomarker solutions to advance molecular medicine, has produced a new, free-to-download application note on combined array comparative genomic hybridisation (aCGH) and single nucleotide polymorphism (SNP) arrays.
The application note, titled ‘Detecting copy number variants and runs of homozygosity on a single array — challenges and applications’ aims to support researchers in navigating this combined approach for the simultaneous detection of copy number variations (CNVs) and runs of homozygosity (ROH). aCGH has established itself as the “gold-standard” platform for array-based CNV detection. Recent advances have enabled the combination of aCGH probes for CNV detection with probes able to detect SNPs...
Drawing upon many years’ experience of designing and supplying liquid flowmeters to meet stringent OEM specifications - Titan Enterprises has produced an informative white paper 'How to specify liquid flowmeters'.
Accurate, reliable, cost effective flow measurement is more important today than it has ever been. However the optimal liquid flowmeter varies considerably according to a wide range of operational parameters including pipe bore, flow path, liquid viscosity, particulate levels, measurement accuracy, measurement dynamic range, maintenance and target purchase price...
New website designed as an easy point of reference for Stomacher® applications and protocols
Seward Limited, founding manufacturer and developer of the world leading, patented Stomacher® Laboratory Paddle Blender range, has launched a new, fully refreshed website. This is designed as a readily accessible point of reference for customers seeking assistance in sample preparation for microbiological analysis in the food, life science and environmental sectors. New to the Seward website includes a Resource Centre to help visitors identify how the Stomacher® may be used. In addition, user guides and technical data are available for download, with useful videos demonstrating various routine protocols...
Nanounity announces the public launch of new characterization tools and techniques for the microscopy community. Products from Pemtron & Delmic will debut at the annual 2013 Microscopy & Microanalysis Conference & Exhibition to be held in Indianapolis, August 4-8. The company will be presenting exciting new products of manufacturers from the USA, Korea and Europe.
New instrumentation, tools and techniques, will be featured on the Nanounity booth, #828, at this year's annual M&M meeting being held in Indianapolis, August 4-8, 2013. The Pemtron SEMART™ PS-250 scanning electron microscope (SEM) will be making its Nanounity US debut. This intermediate microscope provides users with quick and easy operation offering high performance at a reasonable price, a level that a user might expect to pay at least twice to own. With the power of the PS-230, the PS250 allows users to work with larger samples up to 140 mm while retaining 3 nm spatial resolution. Users may add optional EBSD (Electron Detector Back Scattered) and EDS (Energy Dispersive Spectrometer) for more comprehensive analytical performance...
BBI Solutions, a world leader in immunoassay development and contract manufacturing, will launch its unique range of Recombinant Fab Monoclonal Antibodies on booth #3363 at the American Association for Clinical Chemistry’s (AACC) Annual Meeting and Clinical Lab Expo, on July 28-August 31, 2013, in Houston, Texas.
These matched antibodies pairs, developed using proprietary phage display selection and the Luminex platform, exhibit sub-nanomolar affinities, exceptional sensitivity, and provide assay developers with clinically relevant performance characteristics to 34 biomarkers, with more in development...
Porvair Sciences has announced an application note describing the excellent results achievable from a new 96-well format version of its ChromaTrap chromatin immunoprecipitation (ChIP) assay technology.
Developments in the field of epigenetics are rapidly expanding as researchers elucidate the principles governing gene regulation through the in vivo dynamic binding of proteins to DNA. Key to this is the need to analyse large numbers of high and low abundant regulatory mechanisms to systematically map protein-DNA interactions following pathogen/disease stimulus...
The global pharmaceutical industry is facing many challenges and uncertainties as companies strive to align their businesses with the key trends shaping the global marketplace.
Revenues are coming under increasing pressure as a consequence of pricing controls caused by healthcare reforms and austerity measures, increased competition, and challenges in bringing new drugs and other products to market. So, what are the most important decisions senior management will need to make to respond to these pressures?..
Thermo Fisher Scientific has developed an accurate and reproducible high-performance liquid chromatography (HPLC) method for the single-injection determination of tolterodine and tartrate—the active pharmaceutical ingredient (API) and its counterion—in an encapsulated drug product containing tolterodine tartrate.
Application Note 1047: Simultaneous Determination of Tartaric Acid and Tolterodine in Tolterodine Tartrate demonstrates that this method requires only 13 minutes per analysis. This new approach uses a trimode silica-based column and a detector that is ideal for the determination of counterions, many of which lack a chromophore. Pharmaceutical companies must ensure that a drug product contains the appropriate amount of its API. This is typically validated with an HPLC-based assay...
Xmark Media the organisers of Photonex, the UK's showcase photonics event dedicated to applied optical equipment, biophotonics, fibre optics, lasers, sensing, vision & LIGHT announces the 2013 event. This will be held on the 16 & 17th October at the visitor-friendly Ricoh Arena in Coventry.
Photonics finds ever more uses in research, industry and the consumer environment. Photonics technologies are of increasing importance to scientific research and for industry. Its use is growing by the day as is the Photonex 2013 conference and exhibition. Photonex organisers, Xmark Media, report that there will be a larger exhibit this year featuring an increasingly diverse range of products & services which will ensure the event continues to attract visitors from around the world...
A series of new application notes posted on the Malvern Instruments website describes the quick and easy measurement of surface zeta potential using the zeta potential planar cell for the Zetasizer Nano particle characterization system.
Widely used as an indicator of the stability of particle suspensions and colloidal samples, surface zeta potential is traditionally measured using the specialist technique of streaming potential. Malvern’s Surface Zeta Potential Cell eliminates the need for a dedicated solution, allowing users to measure the zeta potential of surfaces in an aqueous medium on a standard instrument. The application note ‘Determination of the zeta potential of the surface of PTFE’, and others relating to different aspects of the measurement, can now be downloaded from Malvern’s online knowledge center...
Malvern Instruments has published ‘Static Light Scattering Technologies For GPC/SEC Explained’, a valuable guide for anyone assessing the value of a light scattering detector for gel permeation/size exclusion chromatography (GPC/SEC).
JPK Instruments, a world-leading manufacturer of nanoanalytic instrumentation for research in life sciences and soft matter, report on the success of the fifth international symposium on the applications of optical tweezers and related technologies in the life sciences.
Held in Berlin, over 60 delegates enjoyed excellent presentations for an international group of speakers. This year's symposium was held on the 18th June in Berlin at the excellent Palisa De/Umspannwerk Ost. A sweltering Berlin welcomed over sixty scientists from around the world to discuss their results and share scientific knowledge in a relaxed and informal atmosphere. NanoBioVIEWS™ is the name of a series of international meetings initiated by JPK Instruments to further the scientific knowledge exchange on instrumentation and applications of nanotechnology in the life sciences...
Kinesis has published a new Application Note: Extraction of Metaldehyde, Geosmin and 2-Methylisoborneol from Water
The latest TELOS® SPE Application Note from Kinesis highlights the extraction of Metaldehyde, Geosmin and 2-Methylisoborneol from Water. Metaldehyde is a molluscicide whose use has markedly increased in recent years as a result of changing agricultural practices. Geosmin and 2-methylisoborneol (MIB) are naturally occurring alicyclic alcohols which possess potent earthy/musty taste and odour tainting properties. They can occur in raw and potable waters as metabolites derived from various micro-organisms...
Dates Confirmed for Forensics Europe Expo 2014, an Event to Connect the Entire Forensics Industry.
Clarion Defence and Security are pleased to announce Forensics Europe Expo 29-30 April 2014, Olympia, London. Forensics Europe Expo is the premier dedicated international forum for the entire forensics sector and supply chain to source forensic products, equipment and services, as well as providing the definitive source of education, best practice, training and networking. Forensic Professionals are requested to add the show dates, 29-30 April 2014, into their diary today...
A series of new application notes posted on the Malvern Instruments website describes the quick and easy measurement of surface zeta potential using the zeta potential planar cell for the Zetasizer Nano particle characterization system.
Widely used as an indicator of the stability of particle suspensions and colloidal samples, surface zeta potential is traditionally measured using the specialist technique of streaming potential. Malvern’s Surface Zeta Potential Cell eliminates the need for a dedicated solution, allowing users to measure the zeta potential of surfaces in an aqueous medium on a standard instrument....
Thermo Fisher Scientific has developed an efficient high-performance liquid chromatography (HPLC) method using ultraviolet detection for the simultaneous determination in drinking water of all 19 phthalate compounds listed in key environmental regulatory documents.
Application Note 1045: Determination of Phthalates in Drinking Water by UHPLC with UV Detection demonstrates that the phthalates listed in European Union Directive 2005/84/EC, U.S. Environmental Protection Agency Methods 606 and 8061A, the Chinese HJ/T 72-2001, and the Standardization Administration of China GB/T 20388-2006 and GB/T 21911-2008 are well separated on a reversed-phase HPLC column in less than 25 minutes...
Tim Freeman, Managing Director of Freeman Technology, will deliver two lectures at the International Powder and Technology Expo (PTX) in Brazil on the topic of understanding the variability of powder behaviour.
Freeman Technology will also exhibit the FT4 Powder Rheometer® at the event, which takes place from 6-8 August 2013 at the Expo Center Norte in Sao Paolo. This is the first time that the company has participated in an exposition in Brazil and provides an opportunity for those working with powders to learn more about the use....
Read MoreRegister for Science World 2013Jun 28, 2013
Fisher Scientific, part of Thermo Fisher Scientific Inc., the world leader in serving science, today announced the full programme of events for their annual customer show Science World. The event takes place on October 10th at ‘The Point’, Old Trafford and is free to attend.
Now in its fifteenth year, Science World 2013 promises to be better than ever. Featuring more than 75 leading industry names, the event provides visitors with the opportunity to see laboratory products firsthand, including demonstrations, seminars and workshops. Keynote speakers include Ben Goldacre and Marcus Du Sautoy. Among the many benefits for attendees are exclusive offers, vouchers, prize draws, competitions and more. Visitors can also go on a guided tour of The Point, based within Lancashire County Cricket Club which is home to The Ashes 2013. All activities are free....
In a new paper published in Polymers & Polymer Composites (Vol 21, No 1, 2013), researchers at Kingston University in the UK report the results of continuing work to examine the effects of gamma irradiation on intraocular lenses (IOLs) used in cataract surgery. Triple detection gel permeation chromatography (GPC) using the Viscotek TDAmax system from Malvern Instruments was a key analytical tool in this work.
Baljit Ghatora and co-authors examined medical grade poly(methyl methacrylate) (PMMA), which is used especially widely in developing countries to make rigid intraocular lenses and for which low cost, convenient gamma irradiation is increasingly the preferred method for sterilisation. Previous reports have suggested that gamma irradiation has the potential to alter the structural features of the polymer, such as molecular weight and molecular size distribution, which in turn may impact the efficacy and performance of IOLs....
Read MoreSub-Visible Particles: Impact On Therapeutic ProteinsJun 26, 2013
SP Scientific has announced a new LyoLearn webinar, due to run on 27th June 2013, entitled 'Sub-visible Particles: Impacts on Aggregation Pathways, Adverse Immunogenicity and Regulatory Expectations for Therapeutic Proteins'.
During the session, Dr. John Carpenter Professor of Pharmaceutical Sciences and Co-Director of the Center for Pharmaceutical Biotechnology, University of Colorado (USA), discusses key areas and presents the latest results from his research. In addition, he will highlight the particle counting instruments that have been vital to the progress made to date. Over the past several years there has been greatly increasing attention on sub-visible particles in therapeutic protein products...