The global pharmaceutical industry is facing many challenges and uncertainties as companies strive to align their businesses with the key trends shaping the global marketplace.
Revenues are coming under increasing pressure as a consequence of pricing controls caused by healthcare reforms and austerity measures, increased competition, and challenges in bringing new drugs and other products to market. So, what are the most important decisions senior management will need to make to respond to these pressures?..
Thermo Fisher Scientific has developed an accurate and reproducible high-performance liquid chromatography (HPLC) method for the single-injection determination of tolterodine and tartrate—the active pharmaceutical ingredient (API) and its counterion—in an encapsulated drug product containing tolterodine tartrate.
Application Note 1047: Simultaneous Determination of Tartaric Acid and Tolterodine in Tolterodine Tartrate demonstrates that this method requires only 13 minutes per analysis. This new approach uses a trimode silica-based column and a detector that is ideal for the determination of counterions, many of which lack a chromophore. Pharmaceutical companies must ensure that a drug product contains the appropriate amount of its API. This is typically validated with an HPLC-based assay...
Xmark Media the organisers of Photonex, the UK's showcase photonics event dedicated to applied optical equipment, biophotonics, fibre optics, lasers, sensing, vision & LIGHT announces the 2013 event. This will be held on the 16 & 17th October at the visitor-friendly Ricoh Arena in Coventry.
Photonics finds ever more uses in research, industry and the consumer environment. Photonics technologies are of increasing importance to scientific research and for industry. Its use is growing by the day as is the Photonex 2013 conference and exhibition. Photonex organisers, Xmark Media, report that there will be a larger exhibit this year featuring an increasingly diverse range of products & services which will ensure the event continues to attract visitors from around the world...
A series of new application notes posted on the Malvern Instruments website describes the quick and easy measurement of surface zeta potential using the zeta potential planar cell for the Zetasizer Nano particle characterization system.
Widely used as an indicator of the stability of particle suspensions and colloidal samples, surface zeta potential is traditionally measured using the specialist technique of streaming potential. Malvern’s Surface Zeta Potential Cell eliminates the need for a dedicated solution, allowing users to measure the zeta potential of surfaces in an aqueous medium on a standard instrument. The application note ‘Determination of the zeta potential of the surface of PTFE’, and others relating to different aspects of the measurement, can now be downloaded from Malvern’s online knowledge center...
Malvern Instruments has published ‘Static Light Scattering Technologies For GPC/SEC Explained’, a valuable guide for anyone assessing the value of a light scattering detector for gel permeation/size exclusion chromatography (GPC/SEC).
JPK Instruments, a world-leading manufacturer of nanoanalytic instrumentation for research in life sciences and soft matter, report on the success of the fifth international symposium on the applications of optical tweezers and related technologies in the life sciences.
Held in Berlin, over 60 delegates enjoyed excellent presentations for an international group of speakers. This year's symposium was held on the 18th June in Berlin at the excellent Palisa De/Umspannwerk Ost. A sweltering Berlin welcomed over sixty scientists from around the world to discuss their results and share scientific knowledge in a relaxed and informal atmosphere. NanoBioVIEWS™ is the name of a series of international meetings initiated by JPK Instruments to further the scientific knowledge exchange on instrumentation and applications of nanotechnology in the life sciences...
Kinesis has published a new Application Note: Extraction of Metaldehyde, Geosmin and 2-Methylisoborneol from Water
The latest TELOS® SPE Application Note from Kinesis highlights the extraction of Metaldehyde, Geosmin and 2-Methylisoborneol from Water. Metaldehyde is a molluscicide whose use has markedly increased in recent years as a result of changing agricultural practices. Geosmin and 2-methylisoborneol (MIB) are naturally occurring alicyclic alcohols which possess potent earthy/musty taste and odour tainting properties. They can occur in raw and potable waters as metabolites derived from various micro-organisms...
Dates Confirmed for Forensics Europe Expo 2014, an Event to Connect the Entire Forensics Industry.
Clarion Defence and Security are pleased to announce Forensics Europe Expo 29-30 April 2014, Olympia, London. Forensics Europe Expo is the premier dedicated international forum for the entire forensics sector and supply chain to source forensic products, equipment and services, as well as providing the definitive source of education, best practice, training and networking. Forensic Professionals are requested to add the show dates, 29-30 April 2014, into their diary today...
A series of new application notes posted on the Malvern Instruments website describes the quick and easy measurement of surface zeta potential using the zeta potential planar cell for the Zetasizer Nano particle characterization system.
Widely used as an indicator of the stability of particle suspensions and colloidal samples, surface zeta potential is traditionally measured using the specialist technique of streaming potential. Malvern’s Surface Zeta Potential Cell eliminates the need for a dedicated solution, allowing users to measure the zeta potential of surfaces in an aqueous medium on a standard instrument....
Thermo Fisher Scientific has developed an efficient high-performance liquid chromatography (HPLC) method using ultraviolet detection for the simultaneous determination in drinking water of all 19 phthalate compounds listed in key environmental regulatory documents.
Application Note 1045: Determination of Phthalates in Drinking Water by UHPLC with UV Detection demonstrates that the phthalates listed in European Union Directive 2005/84/EC, U.S. Environmental Protection Agency Methods 606 and 8061A, the Chinese HJ/T 72-2001, and the Standardization Administration of China GB/T 20388-2006 and GB/T 21911-2008 are well separated on a reversed-phase HPLC column in less than 25 minutes...
Tim Freeman, Managing Director of Freeman Technology, will deliver two lectures at the International Powder and Technology Expo (PTX) in Brazil on the topic of understanding the variability of powder behaviour.
Freeman Technology will also exhibit the FT4 Powder Rheometer® at the event, which takes place from 6-8 August 2013 at the Expo Center Norte in Sao Paolo. This is the first time that the company has participated in an exposition in Brazil and provides an opportunity for those working with powders to learn more about the use....
Read MoreRegister for Science World 2013Jun 28, 2013
Fisher Scientific, part of Thermo Fisher Scientific Inc., the world leader in serving science, today announced the full programme of events for their annual customer show Science World. The event takes place on October 10th at ‘The Point’, Old Trafford and is free to attend.
Now in its fifteenth year, Science World 2013 promises to be better than ever. Featuring more than 75 leading industry names, the event provides visitors with the opportunity to see laboratory products firsthand, including demonstrations, seminars and workshops. Keynote speakers include Ben Goldacre and Marcus Du Sautoy. Among the many benefits for attendees are exclusive offers, vouchers, prize draws, competitions and more. Visitors can also go on a guided tour of The Point, based within Lancashire County Cricket Club which is home to The Ashes 2013. All activities are free....
In a new paper published in Polymers & Polymer Composites (Vol 21, No 1, 2013), researchers at Kingston University in the UK report the results of continuing work to examine the effects of gamma irradiation on intraocular lenses (IOLs) used in cataract surgery. Triple detection gel permeation chromatography (GPC) using the Viscotek TDAmax system from Malvern Instruments was a key analytical tool in this work.
Baljit Ghatora and co-authors examined medical grade poly(methyl methacrylate) (PMMA), which is used especially widely in developing countries to make rigid intraocular lenses and for which low cost, convenient gamma irradiation is increasingly the preferred method for sterilisation. Previous reports have suggested that gamma irradiation has the potential to alter the structural features of the polymer, such as molecular weight and molecular size distribution, which in turn may impact the efficacy and performance of IOLs....
Read MoreSub-Visible Particles: Impact On Therapeutic ProteinsJun 26, 2013
SP Scientific has announced a new LyoLearn webinar, due to run on 27th June 2013, entitled 'Sub-visible Particles: Impacts on Aggregation Pathways, Adverse Immunogenicity and Regulatory Expectations for Therapeutic Proteins'.
During the session, Dr. John Carpenter Professor of Pharmaceutical Sciences and Co-Director of the Center for Pharmaceutical Biotechnology, University of Colorado (USA), discusses key areas and presents the latest results from his research. In addition, he will highlight the particle counting instruments that have been vital to the progress made to date. Over the past several years there has been greatly increasing attention on sub-visible particles in therapeutic protein products...
New Family of UltraPerformance LC Columns Pushes the Limits of Separation Efficiency and Throughput. Waters Corporation (NYSE:WAT) today introduced CORTECS™ Columns, a new family of 1.6 micron solid-core UltraPerformance LC® Columns that set a new standard in LC column performance. The higher efficiency brought to chromatography with CORTECS Columns allows laboratories to produce greater amounts of information faster with every chromatographic separation...
New White Paper on Pipetting Ergonomics aims to protect researchers
Pipetting is a forceful and repetitive activity, and there is a strong association between pipetting and the occurrence of repetitive motion injuries. In fact, pipetting for just over an hour a day over the course of a year is enough to put researchers at risk, and the chances increase exponentially with workload and age. A new white paper about “The Ergonomics of Pipetting” has now been published by METTLER TOLEDO...
The Pittcon Exposition Committee is now accepting booth space reservations for Pittcon 2014, which will be held March 3-6, 2014, at McCormick Place, North America's premier convention facility, located in Chicago, Illinois.
The discounted rate of $2,300 for a standard 10' x 10' space is available to all exhibitors until July 15, 2013. The cost per booth after July 15, is $2,700. Those who wish to be included in the first round of booth assignments should have their agreements submitted by the end of July, as floor placements will begin August 2013...
A new application note from Porvair Sciences details a protocol for its Chromatrap® ChIP assay kit that has been developed to enrich epigenetic marks from primary human tissue cells.
Chromatrap® Pro-A, the novel solid-based matrix for chromatin immunoprecipitation assays (ChIP) has been successfully used for isolation of high quality chromatin from difficult biopsy material. Focusing on an application to precipitate epigenetic marks from primary endometrial stromal cells - results show high abundant epigenetic marks from 1 million cells isolated from a tissue biopsy, with selective amplification of positive gene targets relative to negative IgG and negative gene loci....
Waters Corporation (NYSE:WAT) has unveiled the new Waters® SYNAPT® G2-Si Mass Spectrometer at the 61st conference of the American Society of Mass Spectrometry (ASMS).
The company is also previewing its UNIFI® CCS Research Edition and the new TransOmics Version 2.0 informatics products for the new SYNAPT G2-Si mass spectrometer and demonstrating their benefits for a variety of small molecule applications and cutting-edge Omics-focused research. The SYNAPT G2-Si System integrates a third dimension of resolution and separation power into a new suite of untargeted and targeted LC/MS/MS workflows. This powerful new tool gives researchers a means with which to gain a deeper understanding of molecular biology and disease mechanisms, to develop the next generation of healthcare treatments or chemical materials, or to screen food products or environmental samples for contaminants...
Buying technician workstations for your laboratory is a major capital expense, deserving of careful consideration to avoid making a costly mistake. The choice can be complicated and there are a number of factors that you should consider.
The key ones include initial purchase price, long term ownership cost, laboratory layout and workstation design, supplier support services, and flexibility. This last one is especially tricky, since it requires a bit of crystal ball to make sure your choice supports changing laboratory environments, due to expansion and consolidation, as well as changing trends in equipment design and usage. Follow these six tips for selecting a laboratory workstation that meets all your current needs, while positioning you to adapt to whatever comes down the parkway....
Discounted Attendee Passes Available for a Limited Time
Experts predict that the stem cell industry will be worth over $5 billion by 2014, reflecting the enormous potential of stem cell technologies in the pharmaceutical industry. In the light of this Oxford Global Conferences are proud to present our Stem Cell Congress, to be held on the 4th & 5th November 2013 at the Copthorne Tara, London Kensington. Over this two day conference our esteemed experts will offer invaluable insights into the latest stem cell applications in translational research as well as exploring advances in bioprocessing and engineering technologies...
Xmark Media announces the launch of Vacuum Expo and its partner conference, Vacuum Symposium. In response to industry needs and enthusiasm, the organisers have added a new meeting this year.
The UK's key event for vacuum and nano technologies and techniques taking place in a vacuum chamber is to be held on the 16th & 17th October 2013 at the Ricoh Arena in Coventry. The past successes of these combined events have shown just how much enthusiasm there is for this a quality, well-organised and low cost event. The 2012 event saw a 30% growth in visitors indicating the healthy state of the industry in the UK....
Read More
Revenues are coming under increasing pressure as a consequence of pricing controls caused by healthcare reforms and austerity measures, increased competition, and challenges in bringing new drugs and other products to market. So, what are the most important decisions senior management will need to make to respond to these pressures?..
Photonics finds ever more uses in research, industry and the consumer environment. Photonics technologies are of increasing importance to scientific research and for industry. Its use is growing by the day as is the Photonex 2013 conference and exhibition. Photonex organisers, Xmark Media, report that there will be a larger exhibit this year featuring an increasingly diverse range of products & services which will ensure the event continues to attract visitors from around the world...
Widely used as an indicator of the stability of particle suspensions and colloidal samples, surface zeta potential is traditionally measured using the specialist technique of streaming potential. Malvern’s Surface Zeta Potential Cell eliminates the need for a dedicated solution, allowing users to measure the zeta potential of surfaces in an aqueous medium on a standard instrument. The application note ‘Determination of the zeta potential of the surface of PTFE’, and others relating to different aspects of the measurement, can now be downloaded from Malvern’s online knowledge center...
Covering the theory and practice of molecular weight measurements using static light scattering, this basic guide serves as both an introduction for those with no prior knowledge of the technique and a reference document for anyone looking to enhance their understanding. The white paper is available as a free download from the Malvern Instruments website
Held in Berlin, over 60 delegates enjoyed excellent presentations for an international group of speakers. This year's symposium was held on the 18th June in Berlin at the excellent Palisa De/Umspannwerk Ost. A sweltering Berlin welcomed over sixty scientists from around the world to discuss their results and share scientific knowledge in a relaxed and informal atmosphere. NanoBioVIEWS™ is the name of a series of international meetings initiated by JPK Instruments to further the scientific knowledge exchange on instrumentation and applications of nanotechnology in the life sciences... 
Clarion Defence and Security are pleased to announce Forensics Europe Expo 29-30 April 2014, Olympia, London. Forensics Europe Expo is the premier dedicated international forum for the entire forensics sector and supply chain to source forensic products, equipment and services, as well as providing the definitive source of education, best practice, training and networking. Forensic Professionals are requested to add the show dates, 29-30 April 2014, into their diary today...
Widely used as an indicator of the stability of particle suspensions and colloidal samples, surface zeta potential is traditionally measured using the specialist technique of streaming potential. Malvern’s Surface Zeta Potential Cell eliminates the need for a dedicated solution, allowing users to measure the zeta potential of surfaces in an aqueous medium on a standard instrument....
Freeman Technology will also exhibit the FT4 Powder Rheometer® at the event, which takes place from 6-8 August 2013 at the Expo Center Norte in Sao Paolo. This is the first time that the company has participated in an exposition in Brazil and provides an opportunity for those working with powders to learn more about the use....
Now in its fifteenth year, Science World 2013 promises to be better than ever. Featuring more than 75 leading industry names, the event provides visitors with the opportunity to see laboratory products firsthand, including demonstrations, seminars and workshops. Keynote speakers include Ben Goldacre and Marcus Du Sautoy. Among the many benefits for attendees are exclusive offers, vouchers, prize draws, competitions and more. Visitors can also go on a guided tour of The Point, based within Lancashire County Cricket Club which is home to The Ashes 2013. All activities are free....
Baljit Ghatora and co-authors examined medical grade poly(methyl methacrylate) (PMMA), which is used especially widely in developing countries to make rigid intraocular lenses and for which low cost, convenient gamma irradiation is increasingly the preferred method for sterilisation. Previous reports have suggested that gamma irradiation has the potential to alter the structural features of the polymer, such as molecular weight and molecular size distribution, which in turn may impact the efficacy and performance of IOLs....
During the session, Dr. John Carpenter Professor of Pharmaceutical Sciences and Co-Director of the Center for Pharmaceutical Biotechnology, University of Colorado (USA), discusses key areas and presents the latest results from his research. In addition, he will highlight the particle counting instruments that have been vital to the progress made to date. 
New Family of UltraPerformance LC Columns Pushes the Limits of Separation Efficiency and Throughput. Waters Corporation (NYSE:WAT) today introduced CORTECS™ Columns, a new family of 1.6 micron solid-core UltraPerformance LC® Columns that set a new standard in LC column performance. The higher efficiency brought to chromatography with CORTECS Columns allows laboratories to produce greater amounts of information faster with every chromatographic separation...
Pipetting is a forceful and repetitive activity, and there is a strong association between pipetting and the occurrence of repetitive motion injuries. In fact, pipetting for just over an hour a day over the course of a year is enough to put researchers at risk, and the chances increase exponentially with workload and age. 
The discounted rate of $2,300 for a standard 10' x 10' space is available to all exhibitors until July 15, 2013. The cost per booth after July 15, is $2,700. Those who wish to be included in the first round of booth assignments should have their agreements submitted by the end of July, as floor placements will begin August 2013...
The key ones include initial purchase price, long term ownership cost, laboratory layout and workstation design, supplier support services, and flexibility. This last one is especially tricky, since it requires a bit of crystal ball to make sure your choice supports changing laboratory environments, due to expansion and consolidation, as well as changing trends in equipment design and usage. Follow these six tips for selecting a laboratory workstation that meets all your current needs, while positioning you to adapt to whatever comes down the parkway....
The UK's key event for vacuum and nano technologies and techniques taking place in a vacuum chamber is to be held on the 16th & 17th October 2013 at the Ricoh Arena in Coventry. The past successes of these combined events have shown just how much enthusiasm there is for this a quality, well-organised and low cost event. The 2012 event saw a 30% growth in visitors indicating the healthy state of the industry in the UK....