The Cambridge Crystallographic Data Centre (CCDC), world leading providers of structural chemistry data and insights for materials and life sciences, have announced an update to their Mercury software, a widely adopted solution for crystal structure visualisation, exploration and analysis.The CCDC curates a database of nearly one million experimentally determined chemical structures – the Cambridge Structural Database (CSD)....
Testa Analytical Solutions e.K reports on a growing number of customers using their Nanobrook ZetaPALS instrument to accurately determine the size and surface charge of liposomes, exosomes and microvesicles. A new application note is available describing how the Nanobrook ZetaPALS instrument, using a phase analysis light scattering technique, has been used to accurately determine the size and surface charge of liposomes, exosomes and microvesicles....
Technology company Semcon is increasing its focus on Life Science. Smart technical solutions can be used to improve care and welfare for patients and healthcare staff alike. A new framework agreement has also been concluded with AstraZeneca, applicable to everything from product and production development to product information. “We have extensive experience of Life Science, developing digital...
With years of experience in the pharmaceutical and life science sector, Creative Diagnostics launches NanoHollows, which contain cavity enclosed by a non-porous nanoshell. NanoHollows have great potential applications in biological sensing, biomedical imaging and photothermal therapy due to their unique localized surface plasmon resonance (LSPR) feature...
Incorrect capillary blood sampling is most common reason for inaccurate POC hemoglobin results. EKF Diagnostics, the global in vitro diagnostics company, has published an Educational Guide which provides a quick overview of capillary blood sampling best practice. It aims to help health care professionals understand common causes of pre-analytical errors and reduce their impact on hemoglobin results...
By Rajeev Sehgal, Director of Informatics at BD (Becton, Dickinson and Company)
Microbiology laboratories are facing challenges on a number of fronts: cost pressures and staff shortages constrain their ability to process samples, and increasing test volumes make it difficult for some labs to run tests and get results back to clinicians in a timely manner. Microbiology labs are constantly juggling at least four key priorities....
Genevac has published a technical article that describes how its Rocket™ Evaporator has been used by the Technical University of Munich (Germany) as a sample preparation tool for extraction of active phytochemicals from the leaves of Gymnema sylvestre. A Genevac Rocket Evaporator was chosen to dry the samples because of its high-volume sample capacity, unique technology that eliminates cross contamination due...
A new case study from Autoscribe Informatics discusses the useof the Matrix LIMS (Laboratory Information Management System) in the Cereal, Milling and Baking Science Laboratory at Allied Technical Centre (ATC). It illustrates how a flexible, configurable LIMS can be adapted by the users themselves to meet changing requirements....
We are happy to share our latest application note where we demonstrate how the FLS1000 Photoluminescence Spectrometer can be used for studying the carrier lifetime in perovskite photovoltaic cells. We are pleased to have worked alongside the research group of Prof. Ifor Samuel at St Andrews University. Halide perovskite materials are revolutionising the field of solar cell research thanks to their low cost and high efficiency...
Postnova Analytics reports on how the inorganic analysis team within LGC (Teddington, UK) has been using the AF2000 Field Flow Fractionation system coupled to Inductively Coupled Plasma Mass Spectrometry (ICP-MS) to characterise nanomaterials in complex food sample matrices. Nanomaterials are known to be present in over 1300 foods and commercial products....
Genevac reports on how its hydrochloric acid (HCl) resistant EZ-2 evaporator offers significant benefits to clinical labs tasked with analysing plasma, blood or urine samples for neonatal disorders. In new born infants, tandem Liquid Chromatography Mass Spectrometry (LC/MS/MS) is a widely used analytical technique to identify metabolic neonatal disorders which include aminoacidemia’s, urea cycle disorders...
ASIT biotech, a Belgian clinical-stage biopharmaceutical company specialized in immunotherapy products for the treatment of allergies, is publishing a new article in the prestigious science journal ALLERGY. ALLERGY is the official journal of the European Academy of Allergy and Clinical Immunology (EAACI). Its task is to promote links between fundamental research and clinical research in the fields of allergies and immunology.....
New application note gives researchers insights and guidance on maximizing HDR-mediated insertion of short fragments in CRISPR genome editing
As an advocate for the genomics age, Integrated DNA Technologies (IDT), has published a new application note on optimization of CRISPR-Cas9 for homology-directed repair (HDR) applications. Available as part of the IDT collection of CRISPR application notes and protocols, this article supports researchers using CRISPR...
FLIR Systems has published a technical article that discusses the benefits of next-generation ROIC and detector material technologies and how they are pushing the boundaries on high-speed thermal imaging of ballistic testing.
For many years, high-speed visible cameras offered the ability to stop motion on fast-moving objects and provided unique insight through slow-motion playback for high-speed applications such as ballistics, munitions and tracking applications....
Fluorescence spectroscopy is regarded as a thorough and flexible technique which can be employed to study and characterize unique materials.
Fluorescence spectroscopy is often used in the life sciences as a means of examining cells and understanding the processes taking place within them. Continual breakthrough developments in the instrumentation used for fluorescence spectroscopy, along with the ongoing availability of new fluorescent materials....
Metrohm is proud to announce an update to the application finder on its website that allows users to search application notes by industry method.
The company’s extensive library features more than 2,000 documents that apply to a variety of industries. Metrohm application notes are concise documents that present real-world instrument data to prove the feasibility of a particular measurement....
The latest software release for the Matrix Gemini Laboratory Information Management System (LIMS) from Autoscribe Informatics provides greater bulk sample registration flexibility and enhanced features for visualisation and communications for users.
These include the ability to define the location of a sampling point on an image, record a screenshot with a single button and add attachments to e-mails generated within the LIMS. These useful new features have all been introduced in response to suggestions from Matrix Gemini users....
Chromatrap® has published a new article that describes a detailed genome wide comparison of native and crosslinked chromatin immunoprecipitation followed by next generation sequencing (ChIP-seq) using the company's patented solid state spin column technology.
Chromatrap® supply high quality N-ChIP-seq and X-ChIP-seq kits. This article compares the enrichment of the histone H3K4me3 modification signal across the whole genome, from chromatin prepared by both methods (native vs cross link)....
Chromatrap® has published a new application note that demonstrates how its unique solid state patented technology provides unrivalled sensitivity allowing users to perform ChIP assays using as few as 1000 cells per immunoprecipitation.
Usually large cell numbers are required for performing ChIP, which poses something of a challenge when dealing with limited starting material. The available techniques for tackling small amounts of sample, rare cell types or difficult cell types which provide low yield of chromatin are usually long and complex, and involve DNA amplification or the spiking of samples with chromatin from another source. In the application note, the authors demonstrate how...
Genevac has published an informative customer article that reviews the development of a new sample preparation method using its EZ-2 centrifugal evaporator to help simplify and accelerate the detection and quantitation of algal toxins in surface water.
Due to a warming global environment there has been a rise in occurrences of cyanobacteria blooms in lakes which can generate cyanotoxins. With surface water a major source of drinking water, the presence of cyano bacterial blooms pose a potential threat to human health. Using Ultra-high Performance Liquid Chromatography (UPLC) researchers have been able to...
The fluorescent probe NR12S detects changes in plasma membrane cholesterol levels
The cell membrane is a bilayer of phospholipids with embedded proteins. It contains cholesterol that determines the membrane’s fluidity, permeability and activity of membrane proteins. Changes in membrane cholesterol are implicated in diseases such as Alzheimer’s and cancer, demanding its investigation....
Chromatrap® has published a new application note that demonstrates how its unique solid state patented technology provides unrivalled sensitivity allowing users to perform ChIP assays using as few as 1000 cells per immunoprecipitation.
Usually large cell numbers are required for performing ChIP, which poses something of a challenge when dealing with limited starting material. The available techniques for tackling small amounts of sample, rare cell types or difficult cell types which provide low yield of chromatin are usually long and complex, and involve DNA amplification or the spiking of samples...