Molnupiravir (Lagevrio®) is an antiviral medication to treat mild to medium COVID-19 infection. Molnupiravir is actually a prodrug of the active substrate N4-hydroxycytidine (NHC), a synthetic ribonucleoside analogue. The treatment leads to the introduction of copying errors during viral RNA replication and by this inhibits the viral reproduction. This new Application Note demonstrates how molnupiravir and its active agent β-d-N4-hydroxycytidine can be separated by using a YMC-Triart C18 UHPLC column...
INTEGRA Biosciences has developed the WELLJET family of dispensers to reduce running costs, increase productivity and provide longer walk-away times for bulk microplate filling and reagent dispensing. Available with or without an automated plate stacker, the WELLJET uses the innovative EasySnap™ dispensing cassette to provide accurate and precise hands-free filling of plates ranging from six to 1536 wells – as well as deep well plates and tube racks in plate format – for a wide range of applications.
Ziath announce the launch of the Mohawk 48 tube selector and picker. Designed to select and pick wide, heavy, or tall tubes - this new system is perfect for retrieving individual whole tissue samples from storage. The Mohawk 48 uses forty-eight solenoid pins to enable a specific frozen or thawed sample tube to be raised and selected when a 48-position tube rack is presented according to a pick list from Excel or a LIMS system...
PhoreMost to deploy its SITESEEKER platform to identify novel targets for Roche’s discovery programmes. PhoreMost Ltd., the UK-based biopharmaceutical company dedicated to 'Drugging the Undruggable®' disease targets, has announced it has entered into a multi-project target discovery collaboration with Roche, one of the world's leading biotechnology companies. Under the terms of the agreement, PhoreMost will receive an upfront payment and is eligible for preclinical success-based milestones...
Torrey Pines Scientific announces its EchoTherm™ RIC40 Peltier-driven, compact Chilling/Heating Dry Baths with temperatures settable from 0.0ºC to 100.0ºC. They are designed for use with Robotic Systems. They are controlled via the RS232 I/O port on each RIC40 unit. The RIC40 measures 4.9” (125 mm) long by 3.3” (82 mm) wide by 3.9” (99 mm) tall without a sample block....
Next-generation sequencing (NGS) is quickly becoming the platform of choice for tumor molecular profiling due to its ability to simultaneously report on multiple biomarkers. However, lengthy turnaround times can limit the clinical utility of these results. To meet the need for rapid genomic insights, Thermo Fisher Scientific has launched the CE-IVD (IVDD) Oncomine Dx Express Test and Oncomine Reporter Dx for use in clinical labs...
Queensgate, a brand of Prior Scientific, has announced the launch of the WP-Z-120A Wafer Stage. Millisecond response times and high bandwidth make the WP-Z-120A wafer positioning system ideal for applications where high throughput is essential. The Wafer Stage can be used in wafer inspection with an optical microscope such as the Prior Scientific OpenStand microscope or an OEM version using various optical or other inspection techniques...
Beckman Coulter Life Sciences, a global leader in laboratory automation and innovation, announces it has acquired ValitaCell Ltd. (“ValitaCell”), a biotechnology company that creates pioneering analytical products and technologies for the biopharmaceutical industry. Headquartered in Dublin, Ireland, ValitaCell creates analytical technologies and products for the biopharmaceutical industry with the goal of reducing new therapeutics' cost and time to market...
Uniqsis has launched ColdChip™ - a new versatile mixer/reactor module enabling researchers to experiment with different chemistries particularly exothermic reactions that need to be safely run in a cooled environment with highly efficient mixing. Compact in design, and requiring no input power, the ColdChip™ is optimised for use with the Uniqsis FlowSyn and FlowLab range of flow reactors as well as standalone pumps....
Waters Corporation announced it is providing both technology and expertise to help advance plant-based protein science in collaboration with researchers of the Plant Protein Innovation Center (PPIC) at the University of Minnesota. Waters scientists will work with PPIC researchers to develop a workflow for measuring the amino acid content of plant-based proteins using a Waters ACQUITY™ Premier UPLC System....
Sakura Finetek Europe, the leader in histopathology, announces the launch of its newest solution Tissue-Tek Genie, an Advanced staining system. With this groundbreaking system, the company enters a new market. By continuous 3rd-party clinical validation performed by NordiQC, Sakura Finetek provides optimal scoring antibodies only, focusing on the optimal result for pathologists and their patients...
Jackson ImmunoResearch, a manufacturer of secondary antibodies and immunoreagents for the life science market, announces a new addition to its range of products for scientists developing immunoassays for the serology and diagnostics markets. JIR Mouse Monoclonal Anti-Human IgE antibodies are the latest addition to our suite of products suitable for diagnostics research and development. Specific for Human IgE antibodies, they complement our existing Anti-Human IgG, IgM, and IgA antibodies...
Tough? Fatty? Fibrous? No problem for Retsch’s GRINDOMIX GM 200 knife mill which is perfectly suited to homogenize dry, oily, fatty, soft and tough sample materials - for analysis results with minimum standard deviation. A range of new accessories makes the GM 200 suitable for cryogenic grinding of very sticky or moist samples by using dry ice. The so-called cryo kit offered by Retsch for this purpose consists of a full-metal knife and a special stainless-steel grinding container with lid....
Researchers at the University of Huddersfield have combined differential scanning calorimetry (DSC) with thermomicroscopy to reveal detailed energy changes in specific materials. In this first ever study that uses DSC-thermomicroscopy to harness the benefits of analysing rubidium nitrate and polyethylene oxidation using both methods simultaneously, researchers at the University of Huddersfield’s Thermal Methods Research Unit (TMRU) used the Optical DSC450 System from Linkam Scientific Instruments...
Following varieties of certified reference materials such as environmental standards, food & beverage standards, forensic and veterinary standards, life sciences standards, petrochemical standards, and pharmaceutical and drug standards, earlier this month, Alfa Chemistry commenced the supply of clinical standards for customers worldwide to support clinical laboratory use...
Delong Instruments is proud to announce the launch of its newest instrument, the LVEM 25E compact electron microscope. Built on the same LVEM platform as the widely used benchtop LVEM5, and compact LVEM25, the LVEM 25E is a truly ‘All in One’ electron microscope. The LVEM25E is the first LVEM to be equipped with Energy Dispersive Spectroscopy (EDS) for elemental analysis, complementing the TEM, STEM, SEM and ED capabilities already found in all of its other systems...
Manufactured to the ANSI/SLAS standard, the range of reagent reservoirs from Porvair Sciences are designed for simple integration into any automated liquid handling system. Moulded from high-purity polypropylene, in a Class 10,0000 cleanroom environment, Porvair reagent reservoirs offer chemical compatibility with most organic solvents, acids and bases. High heat resistance allows the reagent reservoirs to be autoclaved clean...
In collaboration with Swiss experts in precision manufacturing from CSEM, 3Brain AG has announced an exciting 3D microchip for their brain-on-chip portfolio. This first-in-class cell-electronic interface technology will allow scientists to study the complexity of 3D cellular networks at unrivaled scale and precision – and to gain novel mechanistic insights into the inner workings of the most complex structure in the universe, the human brain....
Bio-Rad Laboratories, Inc., a global leader in life science research and clinical diagnostic products, has introduced a range of type 1 antibodies that inhibit the binding of evolocumab (Repatha®) to its target, human proprotein convertase subtilisin/kexin type 9 (PCSK9), a protein that has been shown to play a key role in the regulation of cholesterol levels. These sequence-defined, recombinant antibodies are suitable for developing highly selective and sensitive pharmacokinetic (PK) and anti-drug antibody (ADA) assays for evolocumab and its biosimilars.
Are you planning a live cell imaging experiment? Do you want to get stunning time-lapse images with maximal quality? Thistle Scientific proudly introduce the new ibidi Silver Line stage top incubators. Building on the success of ibidi's current range of stage top incubators, the Silver Line range provides an optimal environment for cell growth during live cell imaging...
Shimadzu, a global leader in analytical instrumentation, has announced the release of the MALDI-8030. The new instrument offers a versatile, space-saving, easy-to-use, high-performance alternative, and expands the range of solutions offered by Shimadzu's industry-standard family of benchtop matrix-assisted laser-desorption/ionization time-of-flight (MALDI-TOF) mass spectrometers...
Learn about CRISPR technology’s impact on cell and gene therapies and drug discovery and discover tips and tricks for optimized CRISPR editing and screening. On September 20, 2022, Lonza will host a free virtual workshop on using genome editing technologies for cell and gene therapies and drug discovery. The 3-hour workshop brings together renowned genome editing experts from across industry and academia and comprises four interactive speaker sessions....
Molnupiravir (Lagevrio®) is an antiviral medication to treat mild to medium COVID-19 infection. Molnupiravir is actually a prodrug of the active substrate N4-hydroxycytidine (NHC), a synthetic ribonucleoside analogue. The treatment leads to the introduction of copying errors during viral RNA replication and by this inhibits the viral reproduction. This new Application Note demonstrates how molnupiravir and its active agent β-d-N4-hydroxycytidine can be separated by using a YMC-Triart C18 UHPLC column...
INTEGRA Biosciences has developed the WELLJET family of dispensers to reduce running costs, increase productivity and provide longer walk-away times for bulk microplate filling and reagent dispensing. Available with or without an automated plate stacker, the WELLJET uses the innovative EasySnap™ dispensing cassette to provide accurate and precise hands-free filling of plates ranging from six to 1536 wells – as well as deep well plates and tube racks in plate format – for a wide range of applications.
Ziath announce the launch of the Mohawk 48 tube selector and picker. Designed to select and pick wide, heavy, or tall tubes - this new system is perfect for retrieving individual whole tissue samples from storage. The Mohawk 48 uses forty-eight solenoid pins to enable a specific frozen or thawed sample tube to be raised and selected when a 48-position tube rack is presented according to a pick list from Excel or a LIMS system...
PhoreMost to deploy its SITESEEKER platform to identify novel targets for Roche’s discovery programmes. PhoreMost Ltd., the UK-based biopharmaceutical company dedicated to 'Drugging the Undruggable®' disease targets, has announced it has entered into a multi-project target discovery collaboration with Roche, one of the world's leading biotechnology companies. Under the terms of the agreement, PhoreMost will receive an upfront payment and is eligible for preclinical success-based milestones...
Torrey Pines Scientific announces its EchoTherm™ RIC40 Peltier-driven, compact Chilling/Heating Dry Baths with temperatures settable from 0.0ºC to 100.0ºC. They are designed for use with Robotic Systems. They are controlled via the RS232 I/O port on each RIC40 unit. The RIC40 measures 4.9” (125 mm) long by 3.3” (82 mm) wide by 3.9” (99 mm) tall without a sample block....
Next-generation sequencing (NGS) is quickly becoming the platform of choice for tumor molecular profiling due to its ability to simultaneously report on multiple biomarkers. However, lengthy turnaround times can limit the clinical utility of these results. To meet the need for rapid genomic insights, Thermo Fisher Scientific has launched the CE-IVD (IVDD) Oncomine Dx Express Test and Oncomine Reporter Dx for use in clinical labs...
Queensgate, a brand of Prior Scientific, has announced the launch of the WP-Z-120A Wafer Stage. Millisecond response times and high bandwidth make the WP-Z-120A wafer positioning system ideal for applications where high throughput is essential. The Wafer Stage can be used in wafer inspection with an optical microscope such as the Prior Scientific OpenStand microscope or an OEM version using various optical or other inspection techniques...
Beckman Coulter Life Sciences, a global leader in laboratory automation and innovation, announces it has acquired ValitaCell Ltd. (“ValitaCell”), a biotechnology company that creates pioneering analytical products and technologies for the biopharmaceutical industry. Headquartered in Dublin, Ireland, ValitaCell creates analytical technologies and products for the biopharmaceutical industry with the goal of reducing new therapeutics' cost and time to market...
Uniqsis has launched ColdChip™ - a new versatile mixer/reactor module enabling researchers to experiment with different chemistries particularly exothermic reactions that need to be safely run in a cooled environment with highly efficient mixing. Compact in design, and requiring no input power, the ColdChip™ is optimised for use with the Uniqsis FlowSyn and FlowLab range of flow reactors as well as standalone pumps....
Waters Corporation announced it is providing both technology and expertise to help advance plant-based protein science in collaboration with researchers of the Plant Protein Innovation Center (PPIC) at the University of Minnesota. Waters scientists will work with PPIC researchers to develop a workflow for measuring the amino acid content of plant-based proteins using a Waters ACQUITY™ Premier UPLC System....
Sakura Finetek Europe, the leader in histopathology, announces the launch of its newest solution Tissue-Tek Genie, an Advanced staining system. With this groundbreaking system, the company enters a new market. By continuous 3rd-party clinical validation performed by NordiQC, Sakura Finetek provides optimal scoring antibodies only, focusing on the optimal result for pathologists and their patients...
Jackson ImmunoResearch, a manufacturer of secondary antibodies and immunoreagents for the life science market, announces a new addition to its range of products for scientists developing immunoassays for the serology and diagnostics markets. JIR Mouse Monoclonal Anti-Human IgE antibodies are the latest addition to our suite of products suitable for diagnostics research and development. Specific for Human IgE antibodies, they complement our existing Anti-Human IgG, IgM, and IgA antibodies...
Tough? Fatty? Fibrous? No problem for Retsch’s GRINDOMIX GM 200 knife mill which is perfectly suited to homogenize dry, oily, fatty, soft and tough sample materials - for analysis results with minimum standard deviation. A range of new accessories makes the GM 200 suitable for cryogenic grinding of very sticky or moist samples by using dry ice. The so-called cryo kit offered by Retsch for this purpose consists of a full-metal knife and a special stainless-steel grinding container with lid....
Researchers at the University of Huddersfield have combined differential scanning calorimetry (DSC) with thermomicroscopy to reveal detailed energy changes in specific materials. In this first ever study that uses DSC-thermomicroscopy to harness the benefits of analysing rubidium nitrate and polyethylene oxidation using both methods simultaneously, researchers at the University of Huddersfield’s Thermal Methods Research Unit (TMRU) used the Optical DSC450 System from Linkam Scientific Instruments...
Following varieties of certified reference materials such as environmental standards, food & beverage standards, forensic and veterinary standards, life sciences standards, petrochemical standards, and pharmaceutical and drug standards, earlier this month, Alfa Chemistry commenced the supply of 
Delong Instruments is proud to announce the launch of its newest instrument, the LVEM 25E compact electron microscope. Built on the same LVEM platform as the widely used benchtop LVEM5, and compact LVEM25, the LVEM 25E is a truly ‘All in One’ electron microscope. The LVEM25E is the first LVEM to be equipped with Energy Dispersive Spectroscopy (EDS) for elemental analysis, complementing the TEM, STEM, SEM and ED capabilities already found in all of its other systems...
Manufactured to the ANSI/SLAS standard, the range of reagent reservoirs from Porvair Sciences are designed for simple integration into any automated liquid handling system. Moulded from high-purity polypropylene, in a Class 10,0000 cleanroom environment, Porvair reagent reservoirs offer chemical compatibility with most organic solvents, acids and bases. High heat resistance allows the reagent reservoirs to be autoclaved clean...
In collaboration with Swiss experts in precision manufacturing from CSEM, 3Brain AG has announced an exciting 3D microchip for their brain-on-chip portfolio. This first-in-class cell-electronic interface technology will allow scientists to study the complexity of 3D cellular networks at unrivaled scale and precision – and to gain novel mechanistic insights into the inner workings of the most complex structure in the universe, the human brain....
Bio-Rad Laboratories, Inc., a global leader in life science research and clinical diagnostic products, has introduced a range of type 1 antibodies that inhibit the binding of evolocumab (Repatha®) to its target, human proprotein convertase subtilisin/kexin type 9 (PCSK9), a protein that has been shown to play a key role in the regulation of cholesterol levels. These sequence-defined, recombinant antibodies are suitable for developing highly selective and sensitive pharmacokinetic (PK) and anti-drug antibody (ADA) assays for evolocumab and its biosimilars.
Are you planning a live cell imaging experiment? Do you want to get stunning time-lapse images with maximal quality? Thistle Scientific proudly introduce the new ibidi Silver Line stage top incubators. Building on the success of ibidi's current range of stage top incubators, the Silver Line range provides an optimal environment for cell growth during live cell imaging...
Shimadzu, a global leader in analytical instrumentation, has announced the release of the MALDI-8030. The new instrument offers a versatile, space-saving, easy-to-use, high-performance alternative, and expands the range of solutions offered by Shimadzu's industry-standard family of benchtop matrix-assisted laser-desorption/ionization time-of-flight (MALDI-TOF) mass spectrometers...
Learn about CRISPR technology’s impact on cell and gene therapies and drug discovery and discover tips and tricks for optimized CRISPR editing and screening. On September 20, 2022, Lonza will host a free virtual workshop on using genome editing technologies for cell and gene therapies and drug discovery. The 3-hour workshop brings together renowned genome editing experts from across industry and academia and comprises four interactive speaker sessions....