Thermo Fisher Scientific has released a new technical note which demonstrates the complete recovery of human hormones from drinking water.
Technical Note 148: Automated Extraction and Determination of Human Hormones in Drinking Water uses our newly released polymeric sorbent extraction cartridges (Thermo Scientific™ Dionex™ SolEx™ SPE HRPHS cartridges) on our solid-phase extraction instrument (Thermo Scientific™ Dionex™ AutoTrace 280 instrument) for the determination of human hormones. The SPE instrument can reduce solvent and labor costs by up to 90% in sample preparation...
Drawing upon a wealth of experience of working with a wide range of 3D cell culture procedures and formats - AMSBIO has produced an extensive 48-page handbook for research scientists looking to culture cells in more physiologically relevant environments.
Over the past two decades, many researchers have actively sought ways to culture cells in 3D. The conclusion reached by many researchers is that there is no single optimal solution, each cell type needs a different environment and many biological processes may need specific methods to study them. Leading the field in the provision of solutions for 3D Cell Culture, AMSBIO’s scientists have distilled the best technologies into a useful guide....
Blood cancers (leukemias) are life-threatening diseases that can devastate the lives of patients and their families. Great progress has been made in treatments to improve the survival of these otherwise invariably fatal conditions. Major advances in the understanding of leukemia genetics for genome sequencing of individual patients has taken us one step further towards realizing personalized medicine for many patients.
In acute myeloid leukemia (AML) our understanding of how modifications to DNA molecules that do not result in sequence change (i.e., epigenetic changes) can lead to the development of the disease has paved the way for new more targeted treatments. We will hear about how these new epigenetic targets can be exploited to maintain remission after patients have completed the initial intensive phase of their treatment....
Read MoreBioTek's Think Possible" Video Wins Silver Telly AwardApr 25, 2014
BioTek's Think Possible video, created by Hen House Media, was recently awarded a Silver Telly Award in the "Non-Broadcast, Motivational" category as part of the 35th Annual Telly Awards. Standing out from over 12,000 entries, the Silver Telly is the highest honor bestowed upon film and video productions, and awarded to less than 10 percent of entries.
The awards are judged by the Silver Telly Council, which consists of over 500 accomplished media and video industry professionals, each a previous award winner. Entries are judged against a high standard of merit, and winners represent the best work among the most respected advertising agencies, production companies, television stations, cable operators and corporate video departments in the world....
JPK Instruments, a world-leading manufacturer of nanoanalytic instrumentation for research in life sciences and soft matter, reports on the study of the research work of Dr Paul Squires and his colleagues at the University of Warwick.
Dr Paul Squires and Dr Claire Hills from the School of Life Sciences (SLS) at the University of Warwick have international expertise in cell biology, signalling and endocrinology. They are using the JPK CellHesion® 200 system (funded by Diabetes UK) to nurture multi-disciplinary research between SLS and the School of Engineering (Dr K-K Liu) in addition to external collaborations, e.g. Professor Peter Jones (King’s College London). The innovative nanotechnology is being used to explore a range of problems in biomedicine, biology and pharmacokinetics related to the field of energy homeostasis and diabetes...
Read MoreMerck Millipore and VWR Extend Western European Distribution AgreementApr 24, 2014
Provides VWR access to more Merck Millipore products and reagents for chemical and microbiological analysis
Merck Millipore, the Life Science division of Merck, today announced a new non-exclusive, preferred distribution agreement for Western Europe with VWR a global provider of laboratory supplies, equipment and services. The contract includes a range of Merck Millipore products and reagents for chemical and microbiological analysis, which are mainly used in quality control solutions for the pharmaceutical, food and beverage and chemical industries, as well as products for research in the field of organic synthesis and biosciences...
Read MoreNew Chromatography Product HighlightsApr 24, 2014
An overview of some of the latest chromatography products available from Hichrom Limited.
MicroSolv Technologies have launched Cogent Diol, a 4um diol bonded phase suitable for the reversed-phase or aqueous normal-phase analysis of polar compounds, and Cogent UDA, a new unique selectivity phase featuring an eleven carbon chain terminating in a carboxylic acid (undecanoic acid) group. Both columns are based on MicroSolv’s TYPE-C Silica chemistry.....Read MoreAn Integrated Approach to Clinical Genetics ResearchApr 24, 2014
Oxford Gene Technology (OGT), The Molecular Genetics Company, has produced a new whitepaper titled ‘Comprehensive genomic analysis – complementing sequencing with high-resolution CNV detection’.
The free, downloadable whitepaper provides researchers with an opportunity to explore the latest strategies in the genomic characterisation of complex disorders, and to discover how, when used alongside sequencing, microarrays play a vital role in delivering accurate detection of point mutations and single exon copy number aberrations. The new whitepaper explains how utilising a range of available tools builds a more complete picture of inherently complex genetic disorders...
Porvair Sciences has announced a new video that provides an informative introduction to the Ultravap Mistral - a next generation robot-compatible dry down station designed to remove the 'bottleneck' of solvent evaporation from microplates.
Drawing upon Porvair’s market leading position in nitrogen blow down evaporation – the UltraVap Mistral offers a simple, turnkey solution for integrating an automatic dry down step into your automated liquid handling protocol. The UltraVap Mistral is fully optimised to work with robotic liquid handling systems from suppliers including Beckman, Hamilton and Tecan and features a “shuttle” design capable of serving and retrieving microplates to and from the robot deck without further need for off-deck handling....
Read MoreLinkApr 24, 2014
Link Technologies Ltd, an ISO 9001:2008 certified specialist oligonucleotide reagent manufacturer, has expanded its range of lipophilic modifiers for the effective delivery of oligonucleotides into cells.
As oligos continue to be of interest in drug discovery, offering exciting potential as therapeutic agents, there is an increasing demand for improved oligo delivery techniques. Link’s proven collection of lipophilic oligo modification reagents, which include cholesterol and tocopherol modifiers, now also includes 5’-Palmitate-C6-CE Phosphoramidite....
Hichrom has announced an expansion to its range of training courses and seminars to include a range of practical ‘Hands-On’ courses covering all aspects of LC, LC/MS, GC and GC/MS including Advanced GC Injection Techniques.
Additionally, Hichrom is now able to offer courses covering areas such as Sample Preparation, Ion Chromatography, Practical Laboratory Skills, Data Handling and more. In fact, working with experienced experts in their fields, we are confident that we can meet all your chromatography training needs. Initially the new courses will be available for group or on-site bookings but open enrolment courses may be introduced at a later date...
Read MoreChildrenApr 23, 2014
TAP Biosystems, (now part of the Sartorius Stedim Biotech Group), a leading supplier of innovative cell culture systems and consumables for life science applications, today announced its Fill-It™, automated cryovial filling system is being routinely used in clinical trials of novel cell-based cancer immunotherapies at children’s oncology units in three major US hospitals.
The system is being utilised in research labs to help determine the correct dosage of cells to treat children with life-threatening cancers, as well as to create stocks of consistent, high-quality product in cryovials for clinical trials. Scientists at the hospitals are using Fill-It to produce batches of around 400 cryovials per run, with each 1ml vial containing between 40 and 100 million cell/ml of cell immunotherapy, depending on their requirements...
Analytical laboratories standardized on the Waters® Empower® Chromatography Data System (CDS) now have a wider choice of Thermo Scientific chromatography systems and modules which can be integrated into this environment.
Users of Thermo Scientific Dionex UltiMate 3000 series UHPLC and HPLC systems can now drive Thermo Scientific Dionex Corona Veo charged aerosol detectors and Thermo Scientific Dionex UltiMate 3000 ECD-3000RS electrochemical detectors with Waters Empower. The new version 1.12 of Thermo Scientific Dionex Instrument Integration (DII) for Empower enables control of these additional instruments on any LC system controlled by Empower for additional freedom in experimental design....
HORIBA Scientific is pleased to announce the launch of EzPlex, the new flagship instrument of the label-free molecular interaction platform based on Surface Plasmon Resonance imaging (SPRi).
EzPlex gives quantitative and qualitative information on multiplex molecular interaction assays involving oligonucleotides, oligosaccharides, proteins, antibodies, aptamers or even cells and bacteria. The imaging capability dramatically enhances the throughput of conventional SPR and allows from few up to several hundred molecular interactions to be screened and characterized simultaneously. Interaction kinetic profiles can be obtained within minutes and give precious data about binding strength, kinetics and affinity....
Latest Application Note from Wyatt Technology Demonstrates How Absolute Molar Mass can be Measured Using UHPLC SEC-MALS
Wyatt Technology Corporation, the world leader in absolute macromolecular characterization instrumentation and software, has announced the availability of a new application note which outlines the combined use of the Wyatt μDAWN™ multi-angle light scattering (MALS) detector and the Optilab® UT-rEX™ refractive index (RI) detector to measure the absolute molecular weight (or molar mass) and size of eluting species in ultra high performance liquid chromatography (UHPLC)....
Read MoreAre mega M&As back in pharma?Apr 22, 2014
Ranjith Gopinathan, Life Sciences Programme Manager at Frost & Sullivan, comments on the Novartis – GSK deal
The pharmaceutical industry is witnessing a new wave of mergers and acquisitions activities, especially mega M&As. Big pharma companies have historically been fighting, albeit with little success, on various issues such as patent expiry of blockbuster molecules, regulatory hurdles, generics competition, under utilization of resources, declining pipeline due to a low R&D productivity and governmental price control. Biopharmaceutical companies with a strong biologics pipeline and low exposure to patent expiries have become the most attractive acquisition targets....
Read MoreFull list of speakers for the 2nd Annual Next Generation Sequencing Data Congress AnnouncedApr 22, 2014
Oxford Global are pleased to announce the full list of speakers for the 2nd Annual Next Generation Sequencing Data Congress. Taking place on 19th & 20th May at the Copthorne Tara Kensington in London, this event is not to be missed.
Market leaders in temperature controlled microscopy, Linkam Scientific Instruments report on the use of their PE120 stage and Imaging Station in the development of smart energy windows at RavenBrick LLC in the USA.
Since 2006, a small start-up solar technology company, RavenBrick based in Denver, Colorado, has been working on various processes to take them to the forefront of the booming solar technology market through helping builders and architects respond to the energy challenges of the future with green building materials. The company manufactures smart windows which use thermochromatic filter technology to help regulate the temperature of a building by saving energy costs and reducing glare from sunlight....
Read MoreSimplified Determination of Inositol Phosphates in Dried Distillers Grains with SolublesApr 22, 2014
Thermo Fisher Scientific has developed a rapid and reliable sample preparation procedure and ion chromatography-based method to determine the phytate hydrolysis products in dried distillers grains with solubles (DDGS).
Application Note 1070: Determination of Inositol Phosphates in Dried Distillers Grains with Solubles demonstrates the determination of 25 inositol phosphate isomers—InsP2–InsP6—in an in-house prepared reference solution. Separation is achieved in less than 42 minutes using a column designed for high-resolution separations of carbohydrates. Using this separation, inositol phosphates are determined in DDGS....
Two new xGen® next generation sequencing panels to be launched
Integrated DNA Technologies (IDT), the world leader in oligonucleotide synthesis, is extending its portfolio of NGS panels with the addition of the xGen® Inherited Disease and Pan-Cancer Panels. Adding these to the xGen AML Panel which was launched at the end of last year, IDT now offers a range of panels for deep sequencing that can be supplemented to cover a comprehensive range of diseases....
Merck Millipore, the Life Science division of Merck, today introduced a new recombinant protein purification protocol that combines lysis and purification into a single step.
The condensed workflow can be completed in about 45 minutes, reducing processing time by 75% compared to traditional techniques, while delivering high yield and purity. The new protocol requires significantly less hands-on time than the conventional workflow, provides greater consistency and results in more reproducible yields....
International Research Team Relies on CAMECA Atom Probe and Ion Mass Spectrometer to Determine Age and Geochemistry of 4.4-Billion-Year-Old Australian Zircon Crystal
An international team of geoscientists, utilizing advanced microanalytical instruments, has determined that a tiny fragment of zircon crystal from Western Australia is about 4.4 billion years old, making it the oldest confirmed intact piece of the Earth’s crust. The crystal, not much larger than the width of four human hairs, was analyzed using the latest Atom Probe Tomography (APT) and Secondary Ion Mass Spectrometry (SIMS) instrumentation from CAMECA®, a unit of the Materials Analysis Division of AMETEK®, Inc....
Over the past two decades, many researchers have actively sought ways to culture cells in 3D. The conclusion reached by many researchers is that there is no single optimal solution, each cell type needs a different environment and many biological processes may need specific methods to study them. Leading the field in the provision of solutions for 3D Cell Culture, AMSBIO’s scientists have distilled the best technologies into a useful guide....
In acute myeloid leukemia (AML) our understanding of how modifications to DNA molecules that do not result in sequence change (i.e., epigenetic changes) can lead to the development of the disease has paved the way for new more targeted treatments. We will hear about how these new epigenetic targets can be exploited to maintain remission after patients have completed the initial intensive phase of their treatment....
The awards are judged by the Silver Telly Council, which consists of over 500 accomplished media and video industry professionals, each a previous award winner. Entries are judged against a high standard of merit, and winners represent the best work among the most respected advertising agencies, production companies, television stations, cable operators and corporate video departments in the world....
Dr Paul Squires and Dr Claire Hills from the School of Life Sciences (SLS) at the University of Warwick have international expertise in cell biology, signalling and endocrinology. They are using the JPK CellHesion® 200 system (funded by Diabetes UK) to nurture multi-disciplinary research between SLS and the School of Engineering (Dr K-K Liu) in addition to external collaborations, e.g. Professor Peter Jones (King’s College London). The innovative nanotechnology is being used to explore a range of problems in biomedicine, biology and pharmacokinetics related to the field of energy homeostasis and diabetes...
Merck Millipore, the Life Science division of Merck, today announced a new non-exclusive, preferred distribution agreement for Western Europe with VWR a global provider of laboratory supplies, equipment and services. The contract includes a range of Merck Millipore products and reagents for chemical and microbiological analysis, which are mainly used in quality control solutions for the pharmaceutical, food and beverage and chemical industries, as well as products for research in the field of organic synthesis and biosciences...
The free, downloadable whitepaper provides researchers with an opportunity to explore the latest strategies in the genomic characterisation of complex disorders, and to discover how, when used alongside sequencing, microarrays play a vital role in delivering accurate detection of point mutations and single exon copy number aberrations. The new whitepaper explains how utilising a range of available tools builds a more complete picture of inherently complex genetic disorders...
Drawing upon Porvair’s market leading position in nitrogen blow down evaporation – the UltraVap Mistral offers a simple, turnkey solution for integrating an automatic dry down step into your automated liquid handling protocol. The UltraVap Mistral is fully optimised to work with robotic liquid handling systems from suppliers including Beckman, Hamilton and Tecan and features a “shuttle” design capable of serving and retrieving microplates to and from the robot deck without further need for off-deck handling....
As oligos continue to be of interest in drug discovery, offering exciting potential as therapeutic agents, there is an increasing demand for improved oligo delivery techniques. Link’s proven collection of lipophilic oligo modification reagents, which include cholesterol and tocopherol modifiers, now also includes 5’-Palmitate-C6-CE Phosphoramidite....
The system is being utilised in research labs to help determine the correct dosage of cells to treat children with life-threatening cancers, as well as to create stocks of consistent, high-quality product in cryovials for clinical trials. Scientists at the hospitals are using Fill-It to produce batches of around 400 cryovials per run, with each 1ml vial containing between 40 and 100 million cell/ml of cell immunotherapy, depending on their requirements...
EzPlex gives quantitative and qualitative information on multiplex molecular interaction assays involving oligonucleotides, oligosaccharides, proteins, antibodies, aptamers or even cells and bacteria. The imaging capability dramatically enhances the throughput of conventional SPR and allows from few up to several hundred molecular interactions to be screened and characterized simultaneously. Interaction kinetic profiles can be obtained within minutes and give precious data about binding strength, kinetics and affinity....
Wyatt Technology Corporation, the world leader in absolute macromolecular characterization instrumentation and software, has announced the availability of a new application note which outlines the combined use of the Wyatt μDAWN™ multi-angle light scattering (MALS) detector and the Optilab® UT-rEX™ refractive index (RI) detector to measure the absolute molecular weight (or molar mass) and size of eluting species in ultra high performance liquid chromatography (UHPLC)....
