AMSBIO reports on the pioneering work by researchers at the University of Sheffield, UK to measure the interaction between the SARS-CoV-2 Spike S1 protein receptor binding domain (SARS-CoV-2 S1 RBD) and heparin. This has resulted in a new assay which could be a useful first screen for novel inhibitors of coronavirus infection. Evidence is mounting that SARS-CoV-2 uses heparan sulfates (HS) during the initial attachment to hosts cells, and this interaction appears to increase the affinity for the critical receptor, ACE2....
Having launched a unique AI-aided drug discovery platform last month, this company grows quickly with concerted support from many talented researchers and scientists. It offers drug R & D solutions from the perspective of AI for medical institutions and pharmaceutical enterprises worldwide...
The first accreditations for laboratories conducting COVID-19 diagnostic testing have been awarded. The UK’s sole National Accreditation Body (UKAS) is responsible for the managing the accreditation assessments for all laboratories, in a process that is globally recognised. It has granted St Helen’s & Knowsley (STHK) NHS Trust accreditation against ISO 15189 (the medical laboratories standard), whilst the Metropolitan Police (Met) has been awarded accreditation to ISO/IEC 17025 (the general laboratories standard)...
Illumina, Inc. is paving the way for large-scale, next-generation sequencing-based (NGS) COVID-19 testing. The U.S. Food and Drug Administration (FDA) has issued an Emergency Use Authorization (EUA) for the Illumina COVIDSeq™ Test, a high-throughput, sequencing-based, in vitro diagnostic (IVD) workflow enabling the detection of SARS-CoV-2. The end-to-end workflow extends the options available for labs to scale diagnostic testing...
BBI Solutions has welcomed the ‘significant progress’ made by the UK-Rapid Test Consortium (UK-RTC) – of which it is a part – to develop a COVID-19 lateral flow antibody test. Seven weeks ago, the UK Government commissioned the UK-RTC to develop a COVID-19 lateral flow antibody test that can be used by people in their homes. The UK-RTC says it has made ‘significant progress’ in both developing the antibody test, as well as progress with the regulatory and logistics challenges needed....
The introduction of Thermo Scientific Orbitrap Exploris 480 mass spectrometer and new Thermo Scientific Orbitrap Exploris 240 mass spectrometer, in combination with the Biognosys PQ500 kit, has driven the delivery of a streamlined, simplified workflow that provides increased depth of coverage and sensitivity for analysis of blood-derived samples. In addition, the novel FAIMS DIA method, enabled with Thermo Scientific FAIMS Pro interface, uses Field Asymmetric Ion Mobility Spectrometry...
Alfa Chemistry Testing Lab, a professional testing and analysis organization, announced to have released nano-products safety evaluation services for companies and agencies that are engaged with the development and application of nano-products. Nanomaterials exhibit unique physical and chemical properties in contrast with engineered materials. As more nanotechnology products have moved into the marketplace, especially in the public health-related areas such as food, cosmetics or drug...
As part of an ongoing cooperation, Hamilton Storage and Titian Software announce that Titian’s Automated Stores (AMS) control application now connects Hamilton Storage automated storage systems to Titian’s Mosaic sample management software. Using this integrated system, users can easily and efficiently manage multiple automated storage systems from a single interface. The AMS control application is compatible with the following Hamilton Storage automated storage systems...
Accelerated Technology Laboratories, Inc. (ATL), a leader in Laboratory Information Management Systems (LIMS), continues its 2020 LIMS Webcast series on Wednesday, June 17th with Method Validation: Selecting the Ideal Solution. This webcast will provide guidance, show optimized workflows, and suggest tools for selecting and implementing the ideal method validation solution. Attendees will learn how to reduce the time needed to perform these tasks normally by 70 percent....
Are you required to analyse very small sample amounts? Or do you need to analyse very low concentrations of antibodies in different kinds of matrices? By using of microLC-MS/MS, only a very small amount of valuable samples, e.g. solutions prepared for patient application (usually a dilution of the dosage form), is required to identify and quantify. In addition, microLC-MS/MS can also be used to monitor residues on surfaces or materials in hospitals, pharmacies or laboratories that prepare solutions for patient application....
In this new 10-page Technology Note, learn how different image processing methods have the potential to make widefield microscope systems more powerful and versatile. Understand each methods limitations and pitfalls, as well as suitability for your specific applications. For decades, fluorescence microscopy has been an invaluable tool in life sciences research, with new variations and implementations emerging almost every year....
Digital Science, a leading technology company serving emergent needs across the research sector, has released a report highlighting the global research landscape trends and cultural changes in response to the COVID-19 pandemic. The report How COVID-19 is Changing Research Culture analyses publication trends, regional focal points of research, collaboration patterns, and top institutional producers of research in COVID-19....
Analytik reports how the renowned Quadram Institute (Norwich, UK) has invested in a ZetaView Nanoparticle Tracking Analyser to help them develop a new approach for vaccine delivery based on engineering the natural ability of resident gut bacteria to generate nanoparticle sized Outer Membrane Vesicles (OMVs). In combination with the latest developments in recombinant protein production established at the University of Kent, Department of Synthetic Biology and Bioinformatics, researchers at the Quadram Institute have identified key antigen targets within the COVID-19 virus...
As a leading British autoclave manufacturer, Priorclave is delighted to announce that it has gained approval by the SFDA- Saudi Food & Drug Authority for its entire range of range of research grade laboratory autoclaves. This is an important development and will enable the company to further expand its business in the region. Priorclave has developed and manufactures more than 60 standard laboratory models at its UK production facility....
New UK Biobank research, led by the University of Glasgow and published in BMC Medicine, has found that black and south Asian ethnic groups have a higher risk of testing positive with SARS-CoV-2, the virus which causes COVID-19. These groups were also at a higher risk of testing positive while attending hospital, suggesting they were also at greater risk of severe disease from the virus...
At Lab Innovations, the UK’s largest trade exhibition for the laboratory industry, professionals, scientists, researchers and more will come together and do business for the first time in 2020. On 4 & 5 November 2020, at the NEC, Birmingham, the show will open its doors to a visitors and exhibitors with a bigger floor space than ever before. Despite the unfortunate start of the year, where trade shows throughout the country have had to be cancelled or postponed, Lab Innovations is scheduled to drive the business of science once again in 2020...
To assist labs involved with the essential RT-PCR assay part of the “test, trace and isolate” strategy for dealing with the SARS-CoV-2 virus pandemic – Ziath has introduced two optimized packages for reliable tracking of patient samples submitted for Coronavirus (COVID-19) testing. For large-scale, high-density Coronavirus (COVID-19) testing labs...
Avacta and Adeptrix will collaborate to develop and manufacture an Affimer-based BAMS coronavirus antigen test that will provide clinicians with a significant expansion of the available testing capacity for COVID-19 infection in hospitals. Adeptrix’s novel BAMS platform combines enrichment of the sample to improve sensitivity with the power of mass-spectrometry to improve specificity...
Alfa Chemistry Testing Lab, a professional testing and analysis organization, have released nano-products safety evaluation services for companies and agencies that are engaged with the development and application of nano-products. Nanomaterials exhibit unique physical and chemical properties in contrast with engineered materials....
From sourdough starters to biotechnological bugs, micro-organisms make the products society wants and needs. The new European Green Deal is dependent on engineered microbes to make biochemicals to replace oil and synthetic chemicals as building blocks for consumer goods. Microbes can be repurposed to make useful products but one limitation is that many microbes are not able...
Indica Labs, a leading provider of computational pathology software, and Octo, a premiere information technology systems provider to the U.S. Federal Government, are pleased to announce the online COVID Digital Pathology Repository (COVID-DPR), a virtual collection of high resolution microscopic COVID-related human tissue images hosted at the National Institutes of Health....
When UCLA’s Dr. Araceli Espinosa-Jeffrey sent human brain cells into space, her goal was to gain a better understanding of how neural stem cells grow and develop in microgravity. That understanding is key to discovering more about the serious issues of intracranial hypertension affecting astronauts returning from space. The information may also one day be used to further cell replacement therapies...