Porvair Sciences has announced an online video demonstrating its MicroShake™ orbital shaker and how it can be used to accelerate sample preparation when using the company's popular p3 protein precipitation plates
By simply placing a p3 plate on the MicroShake™ dedicated plate holder and agitating for less than 30 seconds - rapid and complete mixing of serum samples with acetonitrile is ensured. The MicroShake™ has been rigorously tested with p3 plates to ensure that no breakthrough of supernatant liquid can occur and has been shown to be the fastest way to ensure protein precipitation throughout the sample....
Read MoreWaters Biopharmaceutical, Bioanalysis and Screening Solutions Now Shipping with UNIFI 1.6Apr 26, 2013
UNIFI 1.6 is Industry’s First Multi-User, Server-Based Technology for Management of Analytical LC, LC/MS, and LC/MS/MS Data
Waters Corporation (NYSE: WAT) is now shipping UNIFI® Scientific Information System, release version 1.6, for the Waters® Biopharmaceutical Platform Solution, Regulated Bioanalysis Platform Solution, Screening Platform Solution, Pesticide Screening Application Solution and Metabolite Identification Application Solution. UNIFI 1.6 features improved software performance, default and customizable workflows capabilities, and multi-user server-based connectivity....
Thermo Scientific™ Barnstead™ water purification systems are designed for you and your applications - from everyday needs to the most critical needs. Benefit from solutions that address the challenges of a shared laboratory environment
Advanced ergonomics, remote dispensing and innovative water monitoring technologies help you produce lab water with ease. Feed water monitoring alerts you to fluctuations in the feed water quality. UV intensity monitoring reduces the risk of false total organic carbon (TOC) values. Design a configuration that best suits your lab. Choose from numerous mounting options, as well as flexible dispensing options. Many systems can be easily upgraded to allow for additional capacity. The portfolio includes two systems that produce both Type 1 and Type 2 water....
Advanced Chromatography Technologies is pleased to announce the launch of ACE SuperC18
These UHPLC and HPLC columns offer excellent stability across an extended pH range (pH 1.5 to 11.5), allowing chromatographers to routinely exploit beneficial selectivity changes at low, intermediate and high pH. ACE SuperC18 columns are designed for use with LC/MS compatible buffers and offer ultra-low bleed for improved LC/MS compatibility. They can be used with both MeOH and MeCN mobile phases and offer rapid column equilibration without memory effects...
Read MoreApr 22, 2013
A two day symposium focussing on today’s challenges to Separation Science posed by Complex Matrices to be held at the Bat Research Labs on 22nd & 23rd May 2013
Chromatographic and mass spectrometric analysis in vegetable matter, smoke aerosols, particulates and products of combustion will be explored by specialists from a variety of industries. An exhibition of analytical instrumentation by leading manufacturers will also form an important element of the symposium....
Wyatt Technology is pleased to report the success of the Calypso® composition-gradient multi-angle light scattering (CG-MALS) system in a study conducting by the Molecular Interactions Research Group (MIRG) of the Association of Biomolecular Research Facilities (ABRF). The conclusions of the 2012 MIRG study were announced at the ABRF 2013 annual meeting in Palm Springs earlier this month.
In the study, a pair of unknown proteins, prepared and characterized by the ABRF, was sent out to multiple labs to determine binding affinity and stoichiometry. In a single afternoon consisting of 2 CG-MALS runs, the Wyatt Calypso system correctly determined that Protein Y (26.3 kDa) contains two binding sites for Protein X (11.9 kDa). The first X binds with KD of 10 nM and the second X binds with 14 μM. This analysis agreed perfectly with extensive analytical ultracentrifugation (AUC) and isothermal titration calorimetry (ITC) measurements performed by ABRF prior to distributing the samples....
Structural Proteomics Laboratory Directed by Prof. Dr. Amit Kumar Mandal Recognized for Global Disease Research
At a ceremony at St. John’s Research Institute (Bangalore, India) Waters announced the selection of the St. John’s Research Institute for its Centers of Innovation Program for research in the field of structural proteomics. It is the first institution in India to receive the designation of a Waters® Center of Innovation. Under the direction of Prof. Dr. Amit Kumar Mandal, a Professor of Molecular Medicine and Clinical Proteomics, St. John’s has earned a reputation for its research in blood disorders and other diseases that disproportionately affect disadvantaged populations...
Merck Millipore, the Life Science division of Merck, has introduced Amicon® Pro Purification System for Protein Purification
This centrifugal device streamlines the affinity purification workflow and minimizes protein loss. Users experience consistent, accurate sample preparation, resulting in more reliable recovery, uncompromised purity and easier data generation.
Centrifugal device streamlines the affinity purification workflow and minimizes protein loss
Combines the bind, wash, elute, buffer exchange and concentration steps into one device
Supports additional applications including depletion of abundant proteins, protein enrichment and clean-up of antibody labeling reactions
It is with much sadness that we write to inform you that Bernie finally lost his battle with a liver condition, with which he had been suffering for the past few years, and died on Saturday evening at around 8:30pm in the UK. The effects of the liver disease had become more pronounced in recent months and, despite various medical attempts to try and treat him, the condition worsened and also started to affect his other major organs. Bernie died peacefully, his wife Jude and son Kevin were with him....
Porvair Sciences announces new versions of its MiniVap and UltraVap blowdown evaporators that use warm air or nitrogen to speed up the evaporation of common HPLC solvents such as dichloromethane, methanol and acetonitrile from sample vials, significantly improving throughput and removing this common laboratory bottleneck
Combining a new 48-well needle head with a dedicated HPLC vial holder that accepts 48 standard 1.5ml vials* transforms any MiniVap or UltraVap system into a high throughput HPLC sample evaporator. Applications that will benefit from the new HPLC sample evaporators include pre-concentration prior to injection (to increase sensitivity) as well as evaporation to dryness of post-column fractions for recovery of compounds....
Read MoreISOLUTE Myco SPE columns, a dedicated product for the efficient extraction of mycotoxins from food matricesApr 9, 2013
Biotage has announced the launch of ISOLUTE® Myco SPE columns, a new product for the ‘catch and release’ clean up of mycotoxins from food matrices, prior to analysis by LC-MS/MS
The ISOLUTE® Myco sorbent is a proprietary polymeric phase (patent pending) optimized for the extraction of a broad spectrum of mycotoxins from a wide range of foodstuffs; enabling chemists to utilize a single SPE product to extract all relevant mycotoxins from an individual foodstuff. Using a single, easy to use sample preparation product, along with optimized matrix specific application notes, scientists can prepare diverse samples for analysis by LC-MS/MS...
Thermo Scientific TriPlus 300 Headspace Autosampler features 120-vial sample tray and 18-vial incubation capacity for high-throughput capability
Thermo Fisher Scientific Inc., the world leader in serving science, has introduced the Thermo Scientific TriPlus 300 Headspace Autosampler, designed for fast start-up, high productivity, and flexibility for analyzing organic volatiles. Throughput of this new valve-and-loop headspace autosampler is enhanced by its 120-vial sample tray capacity and large 18-vial incubation oven overlap capacity, enabling long, unattended high-throughput runs....
Chromeleon 7.2 chromatography data system supports mass spectrometry along with liquid, gas and ion chromatography to simplify workflows
Thermo Fisher Scientific Inc., the world leader in serving science, has introduced the next generation of its gold-standard Chromeleon chromatography data system (CDS), which now supports mass spectrometry along with mainstream front-end separation techniques in the same software package. Thermo Scientific Dionex Chromeleon 7.2 CDS bridges the gap between gas, liquid, or ion chromatography and mass spectrometry to offer enterprise-wide gains in laboratory productivity....
Based on customer demand Waters Corporation today announced improvements to the Waters Alliance HPLC System. The updated system will maintain key Alliance performance specifications and control algorithms to ensure that analysts can seamlessly replicate their existing methods
“The Alliance HPLC System has been the benchmark for HPLC in the laboratory for nearly two decades. Because of its dependability, high quality and flexible operation, tens of thousands of these systems are used every day to run methods varying from USP monographs to polymer analyses,” said Ian King, Vice President of Separation Technologies for the Waters Division. “Since its introduction, the Alliance HPLC System has been continually enhanced accommodating an enormous range of separation challenge...
Read MorePorvair Sciences Expands Product Range for EpigeneticsApr 4, 2013
Porvair Sciences has announced the addition of the novel Chromatrap chromatin immunoprecipitation (ChIP) assay range to its portfolio of products for epigenetics
Developed in conjunction with Department of Life Sciences at University of Swansea, UK - Chromatrap® uses a solid phase porous polymer functionalised with protein A, allowing the chromatin capture to be more efficient than bead based methods. The Chromatrap spin column approach offers significant advantages compared to methods based on sepharose or magnetic beads, which involve many steps of separation, pipetting and re-suspension. Independent tests with Chromatrap demonstrate levels of DNA pull down up to 25 times higher than with traditional bead based procedures, excellent DNA enrichment with signal-to-noise ratios typically 2 to 3 times better than competing procedures...
Read MoreMarkes International launches new low-flow sampling pump for thermal desorptionApr 3, 2013
Markes International (Llantrisant, UK) has announced the launch of the ACTI-VOC™ low-flow sampling pump specifically for thermal desorption tubes
ACTI-VOC is a robust low-flow pump for sampling vapour-phase organic compounds (VOCs) onto sorbent tubes for subsequent analysis by thermal desorption (TD)–GC(MS). Being lightweight, easy-to-use and intrinsically safe, ACTI-VOC is ideal for personal monitoring and a wide range of other air and gas sampling applications. Unlike other personal monitoring pumps on the market, ACTI-VOC is optimised for sampling onto TD tubes, and automatically compensates for different impedances, ensuring constant flow rates whatever the sorbent packing....
New Thermo Scientific solid-core particle phases, diquat/paraquat columns, size exclusion columns and SureStop 9mm vials exhibited at Pittcon 2013
Thermo Fisher Scientific Inc., the world leader in serving science, have featured a number of new chromatography consumables during Pittcon 2013, being held in Philadelphia from March 17-21, 2013. Among them are several columns designed for improved analysis of chemical compounds. The company has added five phases to its family of Thermo Scientific Accucore solid core HPLC columns...
Thermo Fisher Scientific is pleased to announce a new carbohydrate column, the Thermo Scientific™ CarboPac™ PA10 (0.4 x 50 mm) Capillary Column, optimized for the high sensitivity determination of amino, neutral, and acidic monosaccharides found in carbohydrate moieties of mammalian glycoproteins. The column is also ideal for the separation of alditols and sugars in matrices such as fruits and vegetables
This new polymeric column is packed with 10 μm diameter non-porous beads featuring a cross-linked structure to ensure long column life and stability from pH 0–14 at all concentrations of buffer salts. Advantages of this column include simple, isocratic separations, gradient compatibility, and sample derivatization is not required. The column should be of interest to researchers and chemists in the food and beverage, pharmaceutical and biopharmaceutical markets...
J.G. Finneran is the original designer and manufacturer of the Patented Top Hat™ Septa assembled in a polypropylene 24-400mm closure for use with 20mL, 30mL, 40mL and 60mL sampling vials
No need for bonding, the .125” thick Top Hat™ PTFE/silicone septa and closure are designed to provide a positive physical lock to assure that the preassembled components arrive intact. The unique septa/liner is molded to provide a leak proof seal....
RSA (Reduced Surface Activity) Glass vials are produced by a revolutionary new patent pending production process that virtually eliminates all silanols and produces glass which has a greatly reduced surface activity for basic compounds
RSA Glass vials are not coated or silanized. The lack of surface silanols make RSA Glass vials an excellent choice for many applications. If you are working with sensitive compounds commonly found in natural products, biological samples or chemical synthesis, the glass wall of your vial could be a problem for basic compounds. With RSA Glass vials this problem is eliminated....
Read MoreWaters and Dow Announce Major Breakthrough in Advanced Polymer Analysis at PittconMar 21, 2013
Waters Re-Ignites Innovation in the Chemical Materials Market with ACQUITY APC
Waters ushered in the next era in polymer discovery with the introduction of the ACQUITY APC System. The system, which was developed in collaboration with The Dow Chemical Company, delivers dramatically improved polymer peak resolution, particularly for low molecular weight polymers and oligomers up to 20 times faster than traditional gel permeation chromatography (GPC)...
Read MoreWaters and DANI Instruments Announce Integrated and Compatible NetworkMar 19, 2013
Waters Empower Software Now Works Seamlessly with DANI Headspace and GC instruments
Waters Corporation (NYSE: WAT) and DANI Instruments today announced that Waters® Empower® Chromatography Data Software now provides control for DANI Headspace and Gas Chromatography instruments. Through this partnership, customers will now be able to take advantage of the full potential of both companies.Empower Software enables laboratory-based organizations to protect their original instrument investment by controlling a vast range of chromatographic modules, connecting them to arguably the most powerful data management system and reporting tool in the industry...
By simply placing a p3 plate on the MicroShake™ dedicated plate holder and agitating for less than 30 seconds - rapid and complete mixing of serum samples with acetonitrile is ensured. The MicroShake™ has been rigorously tested with p3 plates to ensure that no breakthrough of supernatant liquid can occur and has been shown to be the fastest way to ensure protein precipitation throughout the sample....
Waters Corporation (NYSE: WAT) is now shipping UNIFI® Scientific Information System, release version 1.6, for the Waters® Biopharmaceutical Platform Solution, Regulated Bioanalysis Platform Solution, Screening Platform Solution, Pesticide Screening Application Solution and Metabolite Identification Application Solution. UNIFI 1.6 features improved software performance, default and customizable workflows capabilities, and multi-user server-based connectivity....
These UHPLC and HPLC columns offer excellent stability across an extended pH range (pH 1.5 to 11.5), allowing chromatographers to routinely exploit beneficial selectivity changes at low, intermediate and high pH. ACE SuperC18 columns are designed for use with LC/MS compatible buffers and offer ultra-low bleed for improved LC/MS compatibility. They can be used with both MeOH and MeCN mobile phases and offer rapid column equilibration without memory effects...
Chromatographic and mass spectrometric analysis in vegetable matter, smoke aerosols, particulates and products of combustion will be explored by specialists from a variety of industries. An exhibition of analytical instrumentation by leading manufacturers will also form an important element of the symposium....
In the study, a pair of unknown proteins, prepared and characterized by the ABRF, was sent out to multiple labs to determine binding affinity and stoichiometry. In a single afternoon consisting of 2 CG-MALS runs, the Wyatt Calypso system correctly determined that Protein Y (26.3 kDa) contains two binding sites for Protein X (11.9 kDa). The first X binds with KD of 10 nM and the second X binds with 14 μM. This analysis agreed perfectly with extensive analytical ultracentrifugation (AUC) and isothermal titration calorimetry (ITC) measurements performed by ABRF prior to distributing the samples....
At a ceremony at St. John’s Research Institute (Bangalore, India) Waters announced the selection of the St. John’s Research Institute for its Centers of Innovation Program for research in the field of structural proteomics. It is the first institution in India to receive the designation of a Waters® Center of Innovation. Under the direction of Prof. Dr. Amit Kumar Mandal, a Professor of Molecular Medicine and Clinical Proteomics, St. John’s has earned a reputation for its research in blood disorders and other diseases that disproportionately affect disadvantaged populations...
This centrifugal device streamlines the affinity purification workflow and minimizes protein loss. Users experience consistent, accurate sample preparation, resulting in more reliable recovery, uncompromised purity and easier data generation.
It is with much sadness that we write to inform you that Bernie finally lost his battle with a liver condition, with which he had been suffering for the past few years, and died on Saturday evening at around 8:30pm in the UK. The effects of the liver disease had become more pronounced in recent months and, despite various medical attempts to try and treat him, the condition worsened and also started to affect his other major organs. Bernie died peacefully, his wife Jude and son Kevin were with him....
Combining a new 48-well needle head with a dedicated HPLC vial holder that accepts 48 standard 1.5ml vials* transforms any MiniVap or UltraVap system into a high throughput HPLC sample evaporator. Applications that will benefit from the new HPLC sample evaporators include pre-concentration prior to injection (to increase sensitivity) as well as evaporation to dryness of post-column fractions for recovery of compounds....
The ISOLUTE® Myco sorbent is a proprietary polymeric phase (patent pending) optimized for the extraction of a broad spectrum of mycotoxins from a wide range of foodstuffs; enabling chemists to utilize a single SPE product to extract all relevant mycotoxins from an individual foodstuff. Using a single, easy to use sample preparation product, along with optimized matrix specific application notes, scientists can prepare diverse samples for analysis by LC-MS/MS...
Thermo Fisher Scientific Inc., the world leader in serving science, has introduced the Thermo Scientific TriPlus 300 Headspace Autosampler, designed for fast start-up, high productivity, and flexibility for analyzing organic volatiles. Throughput of this new valve-and-loop headspace autosampler is enhanced by its 120-vial sample tray capacity and large 18-vial incubation oven overlap capacity, enabling long, unattended high-throughput runs....
Thermo Fisher Scientific Inc., the world leader in serving science, has introduced the next generation of its gold-standard Chromeleon chromatography data system (CDS), which now supports mass spectrometry along with mainstream front-end separation techniques in the same software package. Thermo Scientific Dionex Chromeleon 7.2 CDS bridges the gap between gas, liquid, or ion chromatography and mass spectrometry to offer enterprise-wide gains in laboratory productivity....
“The Alliance HPLC System has been the benchmark for HPLC in the laboratory for nearly two decades. Because of its dependability, high quality and flexible operation, tens of thousands of these systems are used every day to run methods varying from USP monographs to polymer analyses,” said Ian King, Vice President of Separation Technologies for the Waters Division. “Since its introduction, the Alliance HPLC System has been continually enhanced accommodating an enormous range of separation challenge...
Developed in conjunction with Department of Life Sciences at University of Swansea, UK - Chromatrap® uses a solid phase porous polymer functionalised with protein A, allowing the chromatin capture to be more efficient than bead based methods. The Chromatrap spin column approach offers significant advantages compared to methods based on sepharose or magnetic beads, which involve many steps of separation, pipetting and re-suspension. Independent tests with Chromatrap demonstrate levels of DNA pull down up to 25 times higher than with traditional bead based procedures, excellent DNA enrichment with signal-to-noise ratios typically 2 to 3 times better than competing procedures...
ACTI-VOC is a robust low-flow pump for sampling vapour-phase organic compounds (VOCs) onto sorbent tubes for subsequent analysis by thermal desorption (TD)–GC(MS). Being lightweight, easy-to-use and intrinsically safe, ACTI-VOC is ideal for personal monitoring and a wide range of other air and gas sampling applications. Unlike other personal monitoring pumps on the market, ACTI-VOC is optimised for sampling onto TD tubes, and automatically compensates for different impedances, ensuring constant flow rates whatever the sorbent packing....
Thermo Fisher Scientific Inc., the world leader in serving science, have featured a number of new chromatography consumables during Pittcon 2013, being held in Philadelphia from March 17-21, 2013. Among them are several columns designed for improved analysis of chemical compounds. The company has added five phases to its family of Thermo Scientific Accucore solid core HPLC columns...
This new polymeric column is packed with 10 μm diameter non-porous beads featuring a cross-linked structure to ensure long column life and stability from pH 0–14 at all concentrations of buffer salts. Advantages of this column include simple, isocratic separations, gradient compatibility, and sample derivatization is not required. The column should be of interest to researchers and chemists in the food and beverage, pharmaceutical and biopharmaceutical markets...
No need for bonding, the .125” thick Top Hat™ PTFE/silicone septa and closure are designed to provide a positive physical lock to assure that the preassembled components arrive intact. The unique septa/liner is molded to provide a leak proof seal....
RSA Glass vials are not coated or silanized. The lack of surface silanols make RSA Glass vials an excellent choice for many applications. If you are working with sensitive compounds commonly found in natural products, biological samples or chemical synthesis, the glass wall of your vial could be a problem for basic compounds. With RSA Glass vials this problem is eliminated....
Waters ushered in the next era in polymer discovery with the introduction of the ACQUITY APC System. The system, which was developed in collaboration with The Dow Chemical Company, delivers dramatically improved polymer peak resolution, particularly for low molecular weight polymers and oligomers up to 20 times faster than traditional gel permeation chromatography (GPC)...