Kinesis has launched the new TELOS MicroPlate™, a versatile 96-well plate for the extraction of drug molecules from small volume biological fluid samples.

Available as either loose wells or populated plates, the TELOS MicroPlate is available in 5 and 10mg sorbent masses and allows analyte elution in as little as 50µl. The full range of TELOS neo Generic SPE Sorbents (PRP, PCX, WCX, PAX and WAX) are available in this novel format. The TELOS MicroPlate supports both high throughput assays (populated plate) and also those assays with varying sample numbers (loose wells), where the user can populate a plate to individual needs...

Thermo Fisher has developed a multianalyte-targeted technique that uses a spectro-electro array platform to resolve and quantify phenols, phenolic acids, and polyphenolsin a variety of natural products, supplements, herbs, spices, and beverages.

Application Note 1063: Targeted Analyses of Secondary Metabolites in Herbs, Spices, and Beverages Using a Novel Spectro-Electro Array Platformdemonstrates that this approach extends the range of compounds that can be simultaneously detected and enables the separation and quantitation of 49 different phytochemicals commonly found in a number of herbs, spices, and beverages...

Thermo Fisher Scientific has developed an ion chromatography (IC) method for determining low concentrations of morpholine in linezolid using an eluent generation system with suppressed conductivity detection.

Morpholine is used in the synthesis of linezolid and may be present in the drug product. This approach achieves efficient separation using a high-performance cation-exchange column with a high-purity electrolytically generated methanesulfonic acid eluent. Application Note 1062: Determination of Morpholine in Linezolid by Ion Chromatography demonstrates that this IC method also allows simultaneous determination of sodium, ammonium, potassium, and other cations present in the sample...

Organomation announces the newly redesigned MICROVAP product line

These evaporation systems are designed for controlled concentration of small samples.  All four models in the product line are light, compact and digitally controlled for ease of use. The MICROVAP blowdown evaporators are offered in four different models, each providing flexibility for sample preparation applications of different kinds. The single and triple position MICROVAP microplate evaporators, formerly referred to as MICRO-TITERS, concentrate samples held within 96 well plates.  These microplate evaporators can accommodate both deep well and micro well plates.....

Bruker has released an application note on the evaluation of matrix effects on the analysis of carbendazim in orange juice and wine using the EVOQ Elite liquid chromatography mass spectrometer (LC-MS/MS).

Carbendazim is a fungicide and a known endocrine with potentially harmful effects on human health. The US Food and Drug Administration (FDA) has limited the concentration of carbendazim in imports to 10 ppb. Using the EVOQ, Bruker has developed a quantitative Multiple Reaction Monitoring (MRM) method for carbendazim analysis in orange juice and wine matrices. The EVOQ’s sensitivity was demonstrated as detections of 0.005 ppb were made, far below the FDA limit. The application note is available to download...

Genevac has developed a protocol using its SuperCool 75 condenser

Genevac has developed a protocol using its SuperCool 75 condenser that, in conjunction with the Genevac HT-12 High Throughput Evaporator, has been proven to set a new benchmark for enhanced evaporation and lyophilisation results. The SuperCool 75 chills to -75C and operates at higher power than any other commercially available condenser, opening the door to greatly improved results with the Genevac LyoSpeed fast lyophilisation process for preparing powdered samples from HPLC fractions...

Dri-Pure® technology from Genevac offers significant benefits to scientists, especially those working in synthesis and purification. 

This innovative technology enables scientists to rapidly dry their samples without cross-contamination or loss of sample due to solvent bumping. Other methods of solvent removal tend to be very laborious or lead to unacceptable cross-contamination, Dri-Pure® running on a Genevac evaporator gives smooth, controlled solvent removal in optimum time. The patented Dri-Pure® technology is available for all current models of Genevac centrifugal evaporators, from the affordable EZ-2 through to the production-scale HT-24...

Thermo Fisher Scientific has developed a reliable method for determining levels of dithiocarbamate fungicides (DTCs) with high precision using gas chromatography-mass spectrometry (GC-MS).

The complex extraction and identification of DTCs is performed on various food samples after a thorough method validation. Application Note 10333, Analysis of Dithocarbamate Pesticides by GC-MS, compares DTC levels in various food samples to matrix-matched calibration standards. SIM mode analysis provides high selectivity with easy-to-integrate chromatograms. The analysis uses a Thermo Scientific™ TRACE GC Ultra™ gas chromatograph equipped with a Thermo Scientific™ TriPlus™ RSH liquid autosampler coupled to a Thermo Scientific™ ITQ™ 900 ion trap mass spectrometer...

Jenway’s 67 series spectrophotometers offer high quality split-beam optics and a cutting-edge user interface for fast, intuitive operation.

Excellent data portability and secure multi-user operation add to the versatility of these advanced instruments. The 67 series spectrophotometers are covered by a three year warranty which includes the xenon lamp. Both models 6705 and 6715 facilitate measurements from 190nm to 1100nm using a pulsed xenon light source. Model 6715 has an ultra narrow bandwidth of 1.5nm providing even better scanning resolution

Now available, J.G. Finneran Associates manufactures 20mL Clear and Amber Headspace Vials with ceramic write-on spots with graduated marks for easier labeling and identification. 

The graduated marks provide the ability to fill the vial to a desired level and facilitates viewing the sample volumes.  The marking spots can be written on with a #2 pencil.  Our line of headspace vials, are made from only Type I borosilicate glass for durability, heat resistance and low extraction.  The Finneran headspace vials are designed for high pressure strength during the heating process thus reducing the possibility of cracking or strain lines.

Merck Millipore Launches CpGenome™ Direct Prep Bisulfite Modification Kit for Simplified One-Step Conversion of Unmethylated Cytosines

The launch of Malvern Instruments’ Viscotek SEC-MALS 20 chromatography detector has triggered record downloads of one of the supporting white papers ‘Static light scattering technologies for GPC/SEC explained’, underlining the enthusiasm amongst users for straightforward information on GPC/SEC analysis.

The recent addition of Viscotek SEC-MALS 20 to Malvern’s range of detectors puts the company in the unique position of being the sole provider of every commercially available light scattering technology for GPC/SEC. Customers can therefore be assured of a truly unbiased choice of detector solutions. The popular white paper is just one of a suite of educational information and application notes provided by Malvern’s specialist team to help users select the right detector for their application...

Porvair Filtration Group has introduced Hydrofil HTZ – an innovative dual 0.2µm membrane sterilisation filter cartridge that incorporates a pharmaceutical grade, positively charged Nylon 6,6 membrane.

The positive zeta-potential of the nylon membrane enables highly effective reduction of most endotoxins derived from bacteria which typically have a negative charge in water. The dual membrane structure results in a significant increase in the endotoxin adsorption capacity of the filter. Applications for Hydrofil HTZ include GMP pharmaceutical grade water systems where endotoxins levels need to be kept below Limulus Amebocyte Lysate (LAL) assay detection limits and recirculation of parenteral products through endotoxin removal filters to allow batch release...

Wyatt Technology Instrumentation Employed by the Medical Research Council to Perform Breakthrough Research into Human Health and Disease

Wyatt Technology Corporation, the world leader in absolute macromolecular characterization instrumentation and software, today announced that its technology is being used by the Medical Research Council (MRC) Laboratory of Molecular Biology (LMB) to make advancements in tackling specific problems in human health and disease such as understanding different biophysical processes, including mechanisms of viral diseases and immunity....

Thermo Fisher Scientific has developed a simple and economical size-exclusion chromatography (SEC) analysis method that enables nuclear power plants (NPPs) with pressurized water reactors to determine low concentrations of polyacrylic acid (PAA) in secondary feed water containing ethanolamine (ETA) and hydrazine.

Application Note 1058: Determination of Polyacrylic Acid in Nuclear Power Plant Pressurized Water Reactor Secondary Feed Water demonstrates that a SEC column separation with detection at 200 nm can determine PAA with a method detection limit of 2.6 μg/L. This method uses water as the eluent to maximize sensitivity and eliminate the need for eluent preparation...

Worldwide Glass Resources, Inc is pleased to announce that we have expanded our current Headspace vial series to include a writing patch with fill lines.

Benefits & Features

• Writing patches designed with 3 fill lines that provide approximate volume measurements
• Patches manufactured with ceramic paint which accepts ink and pencil
• Ceramic paint meet Rohs standards
• 100% QC - Manufactured using the latest Camera Gauging Systems for consistent reproducibility and tight tolerances
• 100% auto-length gauged
• Manufactured only with Type I Borosilicate glass
• Consistent wall weight for uniform thermal transfer
• Vials available in 18mm Screw Thread Finish, 20mm tapered and 20mm standard finishes which are designed and engineered to work flawlessly with our closures....

Porvair Filtration Group, a world leader in filtration and separation technology, has announced that its Ashland, Virginia production facility is launching a range of 'Made in America' Sinterflo® stainless steel purification filters to cope with increased North American demand for top quality products on short delivery times.

In continuing its initiative to provide a reliable alternate source of high quality products for exacting filtration needs Porvair has invested heavily into its manufacturing facility in the USA and is now making robust, well designed cartridges for the North American market.  All standard cartridge lengths, micron ratings, and end fittings are available in 316L stainless steel format; some within a 24 hour lead time....

MicroSolv Technology Corporation, USA manufacture the unique Cogent TYPE-C™ silica hydride HPLC phases.

These phases show improved column bleed and increased stability over traditional silica based phases. In addition to the unique Cogent TYPE-C™ silica hydride HPLC phases MicroSolv also manufacture a range of high purity Type B silica columns including longer chain C27 and C30 phases. A wide range of application notes are available and summaries of 3 of these are below. Analysis of Tetrahydrocannabinol Metabolite in Urine on Cogent Phenyl Hydride. 9-Carboxy-11-nor-delta 9-tetrahydrocannabinol is the main metabolite of tetrahydrocannabinol (THC), formed in the body after consumption of cannabis...

Thermo Fisher Scientific has developed an on-line solid phase extraction (SPE)high-performance liquid chromatography (HPLC) with ultraviolet absorbance detection method to determine the 14 explosives and related compounds specified in U.S.

Environmental Protection Agency Method 8330A in environmental water samples. Application Note 1066: Sensitive Determination of Explosive Compounds in Waterdemonstrates that this approach eliminates the labor associated with off-line extraction and provides a convenient method that achieves reduced method detection limits (less than 0.35 μg/mL) when determining these compounds in water...

Advanced Chromatography Technologies is pleased to announce the launch of a range of ultra low dispersion, high quality pre-column filters, especially designed for UHPLC and HPLC applications. 

One of the most common causes of LC column failure is particulate material collecting on the inlet frit of the column, causing high back pressure and/or distortion of peak shape. By one estimate, over 70% of LC column failures are caused by inlet frit plugging. UHPLC columns, especially those packed with sub-2μm size particles, are particularly vulnerable to inlet frit plugging. Advanced Chromatography Technologies offers three different ranges of pre-column filters, each designed for column specific protection...

ACE CN-ES is a new range of UHPLC and HPLC columns from Advanced Chromatography Technologies Limited

These columns incorporate the latest in stationary phase design, combining CN polar selectivity with enhanced hydrophobicity, enabling the benefits of both interactions to be fully exploited. The unique ligand design of the ACE CN-ES incorporates an extended alkyl chain spacer between the silica surface and cyano group, which gives extra phase stability and increased column lifetime. ACE CN-ES is suitable for both reversed-phase and normal-phase separations and can be used in 100% aqueous mobile phase conditions. Particle sizes of 2, 3, 5 and 10µm are available...

Thermo Fisher Scientific has developed a reliable method for determining phthalates in alcoholic beverages by single-quadrupole gas chromatography-mass spectrometry.

The method met the special testing requirements set by the China method GB/T 21911-2008 for determining phthalates in food. Application Note 10339, Determination of Phthalates in Liquor Beverages by Single Quadrupole GC-MS, describes a sensitive and accurate single-quadrupole GC-MS method for determining levels of phthalate plasticizers in alcoholic beverages. The method is sensitive, rapid, and accurate, and covers a wide linear range to meet the need for trace level detection of phthalate esters in different types of beverages....