Merck Millipore offers a comprehensive portfolio of reliable and reproducible HPLC separation tools even for the most challenging analysis problems in research and development, quality control, environmental, clinical and biochemical analysis.
Join us at HPLC as Merck Millipore highlights its Chromolith® High Resolution HPLC technology, which offers higher efficiency, improved peak shape, and more than two times lower back-pressure than any particulate packed column with the same dimensions. Additionally, the Chromolith® columns have a more than 30% longer lifetime compared with particulate columns....
Read MoreSolid Phase Microextraction (SPME) Specialty Vials and SealsMay 29, 2013
Thicker Lip Vials, Thin Seals
The new Finneran SPME Vials with a thicker lip are ideal for most SPME applications. The thicker lip vial creates a tighter seal on the vial. The Finneran SPME Vials are manufactured from high quality Type 1 borosilicate glass. This new thicker lip vial is available in 10mL and 20mL capacities. To complete the package – JG Finneran offers the 20m gold magnetic seal, 8mm hole with a thin 0.60” PTFE/silicone seal. The thin seal is a perfect choice for SPME applications. The thin seal extends the life of the needle and is available in blue or clear....
Read MoreNot happy with your ion chromatograph? Switch to Metrohm now and save!May 28, 2013
Anyone thinking about exchanging his existing IC system should not wait any longer and switch to Metrohm now.
Less need for expensive consumables, outstanding warranties and integral, fully automated sample preparation will benefit users with lower running costs, more efficiency, and highly dependable Swiss technology - for routine analysis and research alike. Investing in Metrohm ion chromatography means routine analysis with fewer consumables such as syringe filters and filter caps required. Integral, fully automated sample preparation (inline dilution, inline calibration, inline dialysis) saves time and stress....
Spinnovation Analytical B.V. and Pivot Park have entered into an agreement where Spinnovation will supply analytical services at the newly established life sciences park, while gaining access to Pivot Park’s advanced analytical platform.
Pivot Park, located on the former Organon/Schering Plough/MSD research site in Oss, the Netherlands, is a centre for open-innovation, where facilities, instruments and knowledge are made available to the pharmaceutical and biotech companies based on the site. Spinnovation will further support the park’s research and productivity with its portfolio of analytical services specifically designed to address both the needs of the small-molecule pharmaceutical and the biopharmaceutical industries. The agreement will allow Spinnovation to expand and complement its extensive technology platform, thanks to exclusive access to several high-end analytical instruments....
Read MoreAccelerating Isolation of Oils, Fuels and Fats from Natural SourcesMay 20, 2013
Genevac, world leaders in solvent removal technology, has over 20 year’s experience of supplying evaporators for removal of solvents from oil, fat and fuel samples.
Oils, fats and fuels are normally isolated from natural sources using extraction or separation techniques that present the final sample in a solution of organic solvent. Before analysis such samples must be dried or concentrated. Whether extracting and recovering additives, evaluating lipid content of foods, characterising reclaimed cooking oils before reprocessing / conversion to biofuels, or investigating drillling test samples - oils, fuels and fats can often prove difficult to dry without using very high temperatures which may lead to loss of the more volatile fractions within the sample....
Read MoreDebunking Myths about Peak Area Response of Glycoprotein OligosaccharidesMay 20, 2013
Thermo Fisher Scientific has released a technical note (TN) that challenges the common misconception that there is significant variation in high-performance anion-exchange chromatography with pulsed amperometric detection (HPAE-PAD) peak area response of oligosaccharides.
TN 133: HPAE-PAD Peak Area Response of Glycoprotein Oligosaccharides summarizes the peer-reviewed scientific literature concerning this subject. This review concludes that the variation in HPAE-PAD oligosaccharide response with structure is minimal, especially among sets of similar oligosaccharides such as those found on many glycoproteins.....
Merck Millipore highlights its new ZIC®-HILIC technology, a zwitterionic HILIC phase for LC-MS separation of polar compounds.
Merck Millipore offers a comprehensive portfolio of reliable and reproducible LC-MS separation tools even for the most challenging analysis problems in research and development, quality control, environmental, clinical and biochemical analysis.Merck Millipore will host a breakfast seminar on HILIC and analytical chromatography. Presentations include a discussion on how separation selectivity differs between HILIC columns; models will be shown to explain how to select columns....
Thermo Fisher Scientific Inc., the world leader in serving science, introduced the Thermo Scientific™ Dionex™ ERS™ 500 Electrolytically Regenerated Suppressor which replaces the Thermo Scientific™ Dionex™ SRS™ 300 Self Regenerating Suppressor.
The Dionex ERS 500 Suppressor minimizes dispersion to deliver higher resolution separations, especially when coupled with Thermo Scientific™ Dionex™ 4 µm based IC columns. The Dionex ERS 500 suppressor permits improved compatibility with a wider range of detection techniques including MS, ICP, ICP-MS etc. due to its improved backpressure resilience. Additionally, the Dionex ERS 500 suppressor precludes the need for periodic chemical regeneration, allowing for greater ease of use and reproducibility.....
Scientists at the specialised biotech company PharmAbcine are completing formulation and stability studies in a fraction of the time thanks to an Optim 1000 microvolume protein analysis and characterisation instrument from Avacta Analytical.
PharmAbcine was established in the Republic of Korea in 2008 specifically for the development of human monoclonal antibodies into drugs for the treatment of human diseases, including cancer and inflammatory diseases. With one product already undergoing clinical trials for blocking angiogenesis in glioblastomas, and a second monoclonal in development stages, the Company is keen to use high throughput technologies where possible, as Dr Weon Sup Lee, Head of the R&D Center at PharmAbcine, explained....
Read MorePorvair Sciences Announces Summer Show ProgramMay 17, 2013
Porvair Sciences has announced that its latest applications focused microplates and microplate equipment will be exhibited at Forum LABO, European Lab Automation ASMS and HPLC 2013
Visitors to Porvair’s stands at these important events will be able to meet technical specialists, see the company's new UltraVap Mistral microplate evaporator, recently launched range of HPLC sample evaporators and review a wide selection of high quality microplates. Also available will be copies of new mini catalogues for Porvair’s deep well plates, assay plates plus a special catalogue dedicated to serving the North American market....
Read MoreOrbital Shaker Helps Accelerate Protein Precipitation Sample PreparationMay 3, 2013
Porvair Sciences has announced an online video demonstrating its MicroShake™ orbital shaker and how it can be used to accelerate sample preparation when using the company's popular p3 protein precipitation plates
By simply placing a p3 plate on the MicroShake™ dedicated plate holder and agitating for less than 30 seconds - rapid and complete mixing of serum samples with acetonitrile is ensured. The MicroShake™ has been rigorously tested with p3 plates to ensure that no breakthrough of supernatant liquid can occur and has been shown to be the fastest way to ensure protein precipitation throughout the sample....
Read MoreWaters Biopharmaceutical, Bioanalysis and Screening Solutions Now Shipping with UNIFI 1.6Apr 26, 2013
UNIFI 1.6 is Industry’s First Multi-User, Server-Based Technology for Management of Analytical LC, LC/MS, and LC/MS/MS Data
Waters Corporation (NYSE: WAT) is now shipping UNIFI® Scientific Information System, release version 1.6, for the Waters® Biopharmaceutical Platform Solution, Regulated Bioanalysis Platform Solution, Screening Platform Solution, Pesticide Screening Application Solution and Metabolite Identification Application Solution. UNIFI 1.6 features improved software performance, default and customizable workflows capabilities, and multi-user server-based connectivity....
Thermo Scientific™ Barnstead™ water purification systems are designed for you and your applications - from everyday needs to the most critical needs. Benefit from solutions that address the challenges of a shared laboratory environment
Advanced ergonomics, remote dispensing and innovative water monitoring technologies help you produce lab water with ease. Feed water monitoring alerts you to fluctuations in the feed water quality. UV intensity monitoring reduces the risk of false total organic carbon (TOC) values. Design a configuration that best suits your lab. Choose from numerous mounting options, as well as flexible dispensing options. Many systems can be easily upgraded to allow for additional capacity. The portfolio includes two systems that produce both Type 1 and Type 2 water....
Advanced Chromatography Technologies is pleased to announce the launch of ACE SuperC18
These UHPLC and HPLC columns offer excellent stability across an extended pH range (pH 1.5 to 11.5), allowing chromatographers to routinely exploit beneficial selectivity changes at low, intermediate and high pH. ACE SuperC18 columns are designed for use with LC/MS compatible buffers and offer ultra-low bleed for improved LC/MS compatibility. They can be used with both MeOH and MeCN mobile phases and offer rapid column equilibration without memory effects...
Read MoreApr 22, 2013
A two day symposium focussing on today’s challenges to Separation Science posed by Complex Matrices to be held at the Bat Research Labs on 22nd & 23rd May 2013
Chromatographic and mass spectrometric analysis in vegetable matter, smoke aerosols, particulates and products of combustion will be explored by specialists from a variety of industries. An exhibition of analytical instrumentation by leading manufacturers will also form an important element of the symposium....
Wyatt Technology is pleased to report the success of the Calypso® composition-gradient multi-angle light scattering (CG-MALS) system in a study conducting by the Molecular Interactions Research Group (MIRG) of the Association of Biomolecular Research Facilities (ABRF). The conclusions of the 2012 MIRG study were announced at the ABRF 2013 annual meeting in Palm Springs earlier this month.
In the study, a pair of unknown proteins, prepared and characterized by the ABRF, was sent out to multiple labs to determine binding affinity and stoichiometry. In a single afternoon consisting of 2 CG-MALS runs, the Wyatt Calypso system correctly determined that Protein Y (26.3 kDa) contains two binding sites for Protein X (11.9 kDa). The first X binds with KD of 10 nM and the second X binds with 14 μM. This analysis agreed perfectly with extensive analytical ultracentrifugation (AUC) and isothermal titration calorimetry (ITC) measurements performed by ABRF prior to distributing the samples....
Structural Proteomics Laboratory Directed by Prof. Dr. Amit Kumar Mandal Recognized for Global Disease Research
At a ceremony at St. John’s Research Institute (Bangalore, India) Waters announced the selection of the St. John’s Research Institute for its Centers of Innovation Program for research in the field of structural proteomics. It is the first institution in India to receive the designation of a Waters® Center of Innovation. Under the direction of Prof. Dr. Amit Kumar Mandal, a Professor of Molecular Medicine and Clinical Proteomics, St. John’s has earned a reputation for its research in blood disorders and other diseases that disproportionately affect disadvantaged populations...
Merck Millipore, the Life Science division of Merck, has introduced Amicon® Pro Purification System for Protein Purification
This centrifugal device streamlines the affinity purification workflow and minimizes protein loss. Users experience consistent, accurate sample preparation, resulting in more reliable recovery, uncompromised purity and easier data generation.
Centrifugal device streamlines the affinity purification workflow and minimizes protein loss
Combines the bind, wash, elute, buffer exchange and concentration steps into one device
Supports additional applications including depletion of abundant proteins, protein enrichment and clean-up of antibody labeling reactions
It is with much sadness that we write to inform you that Bernie finally lost his battle with a liver condition, with which he had been suffering for the past few years, and died on Saturday evening at around 8:30pm in the UK. The effects of the liver disease had become more pronounced in recent months and, despite various medical attempts to try and treat him, the condition worsened and also started to affect his other major organs. Bernie died peacefully, his wife Jude and son Kevin were with him....
Porvair Sciences announces new versions of its MiniVap and UltraVap blowdown evaporators that use warm air or nitrogen to speed up the evaporation of common HPLC solvents such as dichloromethane, methanol and acetonitrile from sample vials, significantly improving throughput and removing this common laboratory bottleneck
Combining a new 48-well needle head with a dedicated HPLC vial holder that accepts 48 standard 1.5ml vials* transforms any MiniVap or UltraVap system into a high throughput HPLC sample evaporator. Applications that will benefit from the new HPLC sample evaporators include pre-concentration prior to injection (to increase sensitivity) as well as evaporation to dryness of post-column fractions for recovery of compounds....
Read MoreISOLUTE Myco SPE columns, a dedicated product for the efficient extraction of mycotoxins from food matricesApr 9, 2013
Biotage has announced the launch of ISOLUTE® Myco SPE columns, a new product for the ‘catch and release’ clean up of mycotoxins from food matrices, prior to analysis by LC-MS/MS
The ISOLUTE® Myco sorbent is a proprietary polymeric phase (patent pending) optimized for the extraction of a broad spectrum of mycotoxins from a wide range of foodstuffs; enabling chemists to utilize a single SPE product to extract all relevant mycotoxins from an individual foodstuff. Using a single, easy to use sample preparation product, along with optimized matrix specific application notes, scientists can prepare diverse samples for analysis by LC-MS/MS...
Thermo Scientific TriPlus 300 Headspace Autosampler features 120-vial sample tray and 18-vial incubation capacity for high-throughput capability
Thermo Fisher Scientific Inc., the world leader in serving science, has introduced the Thermo Scientific TriPlus 300 Headspace Autosampler, designed for fast start-up, high productivity, and flexibility for analyzing organic volatiles. Throughput of this new valve-and-loop headspace autosampler is enhanced by its 120-vial sample tray capacity and large 18-vial incubation oven overlap capacity, enabling long, unattended high-throughput runs....
Join us at HPLC as Merck Millipore highlights its Chromolith® High Resolution HPLC technology, which offers higher efficiency, improved peak shape, and more than two times lower back-pressure than any particulate packed column with the same dimensions. Additionally, the Chromolith® columns have a more than 30% longer lifetime compared with particulate columns....
The new Finneran SPME Vials with a thicker lip are ideal for most SPME applications. The thicker lip vial creates a tighter seal on the vial. The Finneran SPME Vials are manufactured from high quality Type 1 borosilicate glass. This new thicker lip vial is available in 10mL and 20mL capacities. To complete the package – JG Finneran offers the 20m gold magnetic seal, 8mm hole with a thin 0.60” PTFE/silicone seal. The thin seal is a perfect choice for SPME applications. The thin seal extends the life of the needle and is available in blue or clear....
Less need for expensive consumables, outstanding warranties and integral, fully automated sample preparation will benefit users with lower running costs, more efficiency, and highly dependable Swiss technology - for routine analysis and research alike. Investing in Metrohm ion chromatography means routine analysis with fewer consumables such as syringe filters and filter caps required. Integral, fully automated sample preparation (inline dilution, inline calibration, inline dialysis) saves time and stress....
Pivot Park, located on the former Organon/Schering Plough/MSD research site in Oss, the Netherlands, is a centre for open-innovation, where facilities, instruments and knowledge are made available to the pharmaceutical and biotech companies based on the site. Spinnovation will further support the park’s research and productivity with its portfolio of analytical services specifically designed to address both the needs of the small-molecule pharmaceutical and the biopharmaceutical industries. The agreement will allow Spinnovation to expand and complement its extensive technology platform, thanks to exclusive access to several high-end analytical instruments....
Oils, fats and fuels are normally isolated from natural sources using extraction or separation techniques that present the final sample in a solution of organic solvent. Before analysis such samples must be dried or concentrated. Whether extracting and recovering additives, evaluating lipid content of foods, characterising reclaimed cooking oils before reprocessing / conversion to biofuels, or investigating drillling test samples - oils, fuels and fats can often prove difficult to dry without using very high temperatures which may lead to loss of the more volatile fractions within the sample....
TN 133: HPAE-PAD Peak Area Response of Glycoprotein Oligosaccharides summarizes the peer-reviewed scientific literature concerning this subject. This review concludes that the variation in HPAE-PAD oligosaccharide response with structure is minimal, especially among sets of similar oligosaccharides such as those found on many glycoproteins.....
Merck Millipore offers a comprehensive portfolio of reliable and reproducible LC-MS separation tools even for the most challenging analysis problems in research and development, quality control, environmental, clinical and biochemical analysis.Merck Millipore will host a breakfast seminar on HILIC and analytical chromatography. Presentations include a discussion on how separation selectivity differs between HILIC columns; models will be shown to explain how to select columns....
The Dionex ERS 500 Suppressor minimizes dispersion to deliver higher resolution separations, especially when coupled with Thermo Scientific™ Dionex™ 4 µm based IC columns. The Dionex ERS 500 suppressor permits improved compatibility with a wider range of detection techniques including MS, ICP, ICP-MS etc. due to its improved backpressure resilience. Additionally, the Dionex ERS 500 suppressor precludes the need for periodic chemical regeneration, allowing for greater ease of use and reproducibility.....
PharmAbcine was established in the Republic of Korea in 2008 specifically for the development of human monoclonal antibodies into drugs for the treatment of human diseases, including cancer and inflammatory diseases. With one product already undergoing clinical trials for blocking angiogenesis in glioblastomas, and a second monoclonal in development stages, the Company is keen to use high throughput technologies where possible, as Dr Weon Sup Lee, Head of the R&D Center at PharmAbcine, explained....
Visitors to Porvair’s stands at these important events will be able to meet technical specialists, see the company's new UltraVap Mistral microplate evaporator, recently launched range of HPLC sample evaporators and review a wide selection of high quality microplates. Also available will be copies of new mini catalogues for Porvair’s deep well plates, assay plates plus a special catalogue dedicated to serving the North American market....
By simply placing a p3 plate on the MicroShake™ dedicated plate holder and agitating for less than 30 seconds - rapid and complete mixing of serum samples with acetonitrile is ensured. The MicroShake™ has been rigorously tested with p3 plates to ensure that no breakthrough of supernatant liquid can occur and has been shown to be the fastest way to ensure protein precipitation throughout the sample....
Waters Corporation (NYSE: WAT) is now shipping UNIFI® Scientific Information System, release version 1.6, for the Waters® Biopharmaceutical Platform Solution, Regulated Bioanalysis Platform Solution, Screening Platform Solution, Pesticide Screening Application Solution and Metabolite Identification Application Solution. UNIFI 1.6 features improved software performance, default and customizable workflows capabilities, and multi-user server-based connectivity....
These UHPLC and HPLC columns offer excellent stability across an extended pH range (pH 1.5 to 11.5), allowing chromatographers to routinely exploit beneficial selectivity changes at low, intermediate and high pH. ACE SuperC18 columns are designed for use with LC/MS compatible buffers and offer ultra-low bleed for improved LC/MS compatibility. They can be used with both MeOH and MeCN mobile phases and offer rapid column equilibration without memory effects...
Chromatographic and mass spectrometric analysis in vegetable matter, smoke aerosols, particulates and products of combustion will be explored by specialists from a variety of industries. An exhibition of analytical instrumentation by leading manufacturers will also form an important element of the symposium....
In the study, a pair of unknown proteins, prepared and characterized by the ABRF, was sent out to multiple labs to determine binding affinity and stoichiometry. In a single afternoon consisting of 2 CG-MALS runs, the Wyatt Calypso system correctly determined that Protein Y (26.3 kDa) contains two binding sites for Protein X (11.9 kDa). The first X binds with KD of 10 nM and the second X binds with 14 μM. This analysis agreed perfectly with extensive analytical ultracentrifugation (AUC) and isothermal titration calorimetry (ITC) measurements performed by ABRF prior to distributing the samples....
At a ceremony at St. John’s Research Institute (Bangalore, India) Waters announced the selection of the St. John’s Research Institute for its Centers of Innovation Program for research in the field of structural proteomics. It is the first institution in India to receive the designation of a Waters® Center of Innovation. Under the direction of Prof. Dr. Amit Kumar Mandal, a Professor of Molecular Medicine and Clinical Proteomics, St. John’s has earned a reputation for its research in blood disorders and other diseases that disproportionately affect disadvantaged populations...
This centrifugal device streamlines the affinity purification workflow and minimizes protein loss. Users experience consistent, accurate sample preparation, resulting in more reliable recovery, uncompromised purity and easier data generation.
It is with much sadness that we write to inform you that Bernie finally lost his battle with a liver condition, with which he had been suffering for the past few years, and died on Saturday evening at around 8:30pm in the UK. The effects of the liver disease had become more pronounced in recent months and, despite various medical attempts to try and treat him, the condition worsened and also started to affect his other major organs. Bernie died peacefully, his wife Jude and son Kevin were with him....
Combining a new 48-well needle head with a dedicated HPLC vial holder that accepts 48 standard 1.5ml vials* transforms any MiniVap or UltraVap system into a high throughput HPLC sample evaporator. Applications that will benefit from the new HPLC sample evaporators include pre-concentration prior to injection (to increase sensitivity) as well as evaporation to dryness of post-column fractions for recovery of compounds....
The ISOLUTE® Myco sorbent is a proprietary polymeric phase (patent pending) optimized for the extraction of a broad spectrum of mycotoxins from a wide range of foodstuffs; enabling chemists to utilize a single SPE product to extract all relevant mycotoxins from an individual foodstuff. Using a single, easy to use sample preparation product, along with optimized matrix specific application notes, scientists can prepare diverse samples for analysis by LC-MS/MS...
Thermo Fisher Scientific Inc., the world leader in serving science, has introduced the Thermo Scientific TriPlus 300 Headspace Autosampler, designed for fast start-up, high productivity, and flexibility for analyzing organic volatiles. Throughput of this new valve-and-loop headspace autosampler is enhanced by its 120-vial sample tray capacity and large 18-vial incubation oven overlap capacity, enabling long, unattended high-throughput runs....