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Sterilizing Filter Cartridges for the Pharmaceutical Industry

Porvair Filtration Group has introduced Hydrofil HTZ – an innovative dual 0.2µm membrane sterilisation filter cartridge that incorporates a pharmaceutical grade, positively charged Nylon 6,6 membrane.

Porvair Filtration Group has introduced Hydrofil HTZThe positive zeta-potential of the nylon membrane enables highly effective reduction of most endotoxins derived from bacteria which typically have a negative charge in water. The dual membrane structure results in a significant increase in the endotoxin adsorption capacity of the filter.

Applications for Hydrofil HTZ include GMP pharmaceutical grade water systems where endotoxins levels need to be kept below Limulus Amebocyte Lysate (LAL) assay detection limits and recirculation of parenteral products through endotoxin removal filters to allow batch release.

Hydrofil HTZ filters are highly resistant to integrity failure caused by steam sterilisation or autoclave cycles and have excellent chemical compatibility characteristics. Porvair’s sterilising grade cartridges are integrity tested, with each individual module’s value recorded to ensure product safety. The materials of construction are approved by the Federal Drug Administration (FDA) and meet the standards of the United States Pharmacopeia Class VI (USP VI).

Porvair Filtration Group has over 25 years experience in providing innovative solutions that meet the customer’s requirements as well as standards set by regulatory authorities. Manufacturing of Porvair’s high performance, cost effective products is underpinned by a quality assurance programme, cGMP practices and clean room environment to ensure products meet the stringent requirements of the Pharmaceutical, Generics and Veterinary Medicines industry.

Porvair Filtration Group is an international leader in the development and supply of materials and products for applications in filtration and separation. The company's expertise in a wide range of media and the dedication of their design, manufacturing, sales, test and research teams ensure they are at the forefront of filtration technology, delivering world class performance to the Aerospace, Defense, Nuclear, Energy, Chemical Process, Industrial Process, Water Treatment, Printing and Life Science markets. With offices and manufacturing sites located in the UK, Europe and the USA combined with a world-wide network of market representatives and distributors, Porvair prides itself on its investment in continuous innovation and research to meet global demands.


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