Porvair Sciences has published an in-depth application report demonstrating how their Microlute® CP Reverse Phase Solid Phase Extraction (SPE) microplates provide a robust and highly reproducible SPE LC-MS sample preparation methodology for a range of neutral, acidic, and basic analytes. As a sample preparation method - Solid Phase Extraction is widely acknowledged as a 'go to' tool for the clean-up of samples before analysis by hyphenated techniques such as LC/MS or GC/MS...
INTEGRA Biosciences – a leading provider of high quality laboratory equipment – supplies a comprehensive range of liquid handling tools that are ideal for sterile cell biology workflows. Each piece of equipment, from electronic pipettes to robotic pipetting systems and media dispensers, has been expertly designed to fit comfortably under a laminar flow hood to reduce the risk of cell culture contamination....
Merck, a leading science and technology company, has unveiled a representative study on scientific research productivity. Research productivity is defined in this study as the ratio of measurable input (e.g. number of researchers, financial investment) to measurable output (e.g. patents, publications). The study identified four factors that impact on research productivity in organizations worldwide...
Pharmaceutical solutions provider Pharmidex Pharmaceutical Services Ltd has massively increased its testing capacity with the help of a hire purchase solution from Siemens Financial Services (SFS). Founded in 2002, Pharmidex is a Contract Research Organisation (CRO) that provides high-quality bespoke experimental data to support drug discovery and development. Following its Medicines and Healthcare products Regulatory Agency (MHRA) accreditation, the company wanted to invest in the best possible technology to pursue its research...
(Education and Skills Funding Agency) assessment and has been successful in their application to the RoATP (Register of Apprenticeship Training Providers) to deliver apprenticeships to train the lab technicians and scientists of the future. This will help bridge the huge skills shortage of lab technicians and scientists across the UK....
CN Bio, a leading Organ-on-a-chip Company (OOC) that designs and manufactures single- and multi-organ microphysiological systems (MPS), has announced a research collaboration with the Infection Innovation Consortium (iiCON), a global collaborative infectious disease R&D programme, to validate the next generation of COVID-19 research tools. iiCON’s £174 million programme brings together industry, academia, and clinicians to accelerate the discovery, development...
A promising new approach to potentially treat Alzheimer’s disease – and also vaccinate against it – has been developed by a team of UK and German scientists. Both the antibody-based treatment and the protein-based vaccine developed by the team reduced Alzheimer’s symptoms in mouse models of the disease. The research is published in Molecular Psychiatry. The work is a collaboration between researchers at the University of Leicester, the University Medical Center Göttingen and the medical research charity LifeArc....
Eppendorf Lab Channel is a virtual platform where anyone can watch live and on-demand webinars for free, along with new product and application demonstrations. Peek over the shoulders of Eppendorf experts and let the details and insights illuminate the lab world. Attendees are encouraged to ask questions, interact with the experts, and gain new experiences up close and live....
Guardant Health, Inc. (Nasdaq: GH), a leading precision oncology company, and The Royal Marsden NHS Foundation Trust, one of the United Kingdom’s (UK) leading cancer research organizations, have agreed to enter into a partnership to establish an in-house liquid biopsy testing service using Guardant Health’s industry-leading proprietary digital sequencing platform....
INTEGRA’s VOYAGER adjustable tip spacing pipette is supporting crucial experimental work in longitudinal HIV studies. There have recently been tremendous breakthroughs in treatment of HIV infections, but challenges still remain. Scarlette Abbou, an engineer at the French National Centre for Scientific Research (CNRS), explained her lab’s work in this field: “CD4 T-cells – among others – act as reservoirs for HIV, and are established during the earliest stage of infection....
Hemp and marijuana are becoming more popular because of legalisation in multiple countries. The increase of this market also increases the offer of products and therefore the need to monitor different components. This application focusses on Residual Solvent analysis but Scion Instruments has an extended portfolio including potency analyses (AN091, 92, 93 and 130) and Terpene analysis (AN133 and 136) Residual Solvents are organic volatile products that are often used for the extraction...
Ziath reports how it has worked with the Hubrecht Institute (Utrecht, Netherlands) which has developed a pioneering automated test robot, called STRIP-1, which can process up to 20,000 samples for SARS-CoV-2 testing in just 24 hours. This makes it much faster than all other automated SARS-CoV-2 testing systems used to date. In addition, all samples can be tracked precisely because they have a 2D-barcode on the bottom of each tube that is scanned multiple times throughout the process....
Research on hunger wins 2021 Eppendorf & Science Prize. The American scientist Amber L. Alhadeff, Ph.D., Principal Investigator at the Monell Chemical Senses Center and the University of Pennsylvania, USA has won the 2021 Eppendorf & Science Prize for Neurobiology for her work on the gut-brain control of hunger circuits. Alhadeff’s research has revealed how hunger-sensitive neurons in the brain receive signals from the gastrointestinal tract, and how they influence food intake and other survival behaviors....
Ubiquigent Limited (Ubiquigent) announces the extension and expansion of its long-term collaboration with Bristol Myers Squibb. Under the terms of the agreement, Ubiquigent will provide Bristol Myers Squibb with increased access to its deubiquitylase (DUB) enzyme inhibitor drug discovery platform to provide further support to additional therapeutic areas...
The new Test Labs infection prevention research and test laboratory in Peterborough, which opened officially in January 2021, has achieved prestigious UKAS accreditation in less than twelve months, one of the fastest awards in the history of the accreditation body. Parent company Inivos created the facility after the Covid pandemic redirected government and commercial laboratories’ focus which stretched their capacity....
Sartorius and Waters will partner to implement the BioAccord™ LC-MS System from Waters as a new bioprocess analyzer with data connectivity to Sartorius’ Ambr® multi-parallel bioreactor systems to deliver mass spectral information on drug substances, related analytes and cell culture media. This combination will greatly accelerate and improve the accuracy and speed of tasks from clone selection to bioprocess optimization...
A UK-based aquaculture business aims to remove billions of tonnes of carbon from the atmosphere each year by growing and harvesting floating seaweed in the Atlantic Ocean. Seafields is developing and testing new technologies focused on growing and capturing Sargassum, a seaweed that has escaped its normal environment in the Sargasso Sea and has exploded in growth in the last two decades...
Blood alcohol analysis is one of a variety of headspace methods performed in forensic toxicology laboratories. The Versa was evaluated to determine its suitability to perform an occasional blood alcohol test. Methanol, acetone, ethanol, isopropanol and acetaldehyde along with n-propanol, a typical internal standard, were tested with the Versa headspace instrument....
Centrifugal Partition Chromatography (CPC) or Counter Current Chromatography (CCC), as it is sometimes known, is a cost-effective solution for natural product purification using liquid-liquid phases rather than a solid stationary phase. With no column to replace or silica to recycle, CPC offers low solvent consumption compared with traditional chromatography techniques and requires no extensive pre-treatment of samples....
VectorBuilder Inc., a global leader in vector design, optimization and GMP manufacturing, and Landau Biotechnology Co., a world leader in developing nonhuman primate (NHP) models for clinical research applications, have signed a strategic partnership that will establish the world’s first primate gene therapy R&D center. The center will build advanced vector screening and optimization platforms to provide unique CRO services to the rapidly growing gene and cell therapy industry....
SCION Instruments has recently published its latest Application Note “Analysis of Fusel Alcohols Using HT3 Headspace Sampling”. Fusel alcohols are a common by-product of the fermentation process, but abnormal quantities or types can indicate alcoholic beverage adulteration. Method SSD: TM:200 is a direct injection method for testing these alcohols. The method states that Non-Beverage Alcohol (NBA) products, not miscible with water, cannot be analyzed by this method....
UK-based HydRegen are using a DrySyn OCTO reaction station from Asynt to help develop a next generation biocatalyst system that enables cleaner, safer, and more efficient chemical manufacture. HydRegen spun-out from the Vincent Group in the Dept. of Chemistry at the University of Oxford in March 2021. They are developing novel and sustainable strategies for using the growing toolbox of NADH-dependent redox biocatalysts in chemical synthesis...
Porvair Sciences has published an in-depth application report demonstrating how their Microlute® CP Reverse Phase Solid Phase Extraction (SPE) microplates provide a robust and highly reproducible SPE LC-MS sample preparation methodology for a range of neutral, acidic, and basic analytes. As a sample preparation method - Solid Phase Extraction is widely acknowledged as a 'go to' tool for the clean-up of samples before analysis by hyphenated techniques such as LC/MS or GC/MS...
INTEGRA Biosciences – a leading provider of high quality laboratory equipment – supplies a comprehensive range of liquid handling tools that are ideal for sterile cell biology workflows. Each piece of equipment, from electronic pipettes to robotic pipetting systems and media dispensers, has been expertly designed to fit comfortably under a laminar flow hood to reduce the risk of cell culture contamination....
Merck, a leading science and technology company, has unveiled a representative study on scientific research productivity. Research productivity is defined in this study as the ratio of measurable input (e.g. number of researchers, financial investment) to measurable output (e.g. patents, publications). The study identified four factors that impact on research productivity in organizations worldwide...
Pharmaceutical solutions provider Pharmidex Pharmaceutical Services Ltd has massively increased its testing capacity with the help of a hire purchase solution from Siemens Financial Services (SFS). Founded in 2002, Pharmidex is a Contract Research Organisation (CRO) that provides high-quality bespoke experimental data to support drug discovery and development. Following its Medicines and Healthcare products Regulatory Agency (MHRA) accreditation, the company wanted to invest in the best possible technology to pursue its research...
CN Bio, a leading Organ-on-a-chip Company (OOC) that designs and manufactures single- and multi-organ microphysiological systems (MPS), has announced a research collaboration with the Infection Innovation Consortium (iiCON), a global collaborative infectious disease R&D programme, to validate the next generation of COVID-19 research tools. iiCON’s £174 million programme brings together industry, academia, and clinicians to accelerate the discovery, development...
A promising new approach to potentially treat Alzheimer’s disease – and also vaccinate against it – has been developed by a team of UK and German scientists. Both the antibody-based treatment and the protein-based vaccine developed by the team reduced Alzheimer’s symptoms in mouse models of the disease. The research is published in Molecular Psychiatry. The work is a collaboration between researchers at the University of Leicester, the University Medical Center Göttingen and the medical research charity LifeArc....
Eppendorf Lab Channel is a virtual platform where anyone can watch live and on-demand webinars for free, along with new product and application demonstrations. Peek over the shoulders of Eppendorf experts and let the details and insights illuminate the lab world. Attendees are encouraged to ask questions, interact with the experts, and gain new experiences up close and live....
Guardant Health, Inc. (Nasdaq: GH), a leading precision oncology company, and The Royal Marsden NHS Foundation Trust, one of the United Kingdom’s (UK) leading cancer research organizations, have agreed to enter into a partnership to establish an in-house liquid biopsy testing service using Guardant Health’s industry-leading proprietary digital sequencing platform....
INTEGRA’s VOYAGER adjustable tip spacing pipette is supporting crucial experimental work in longitudinal HIV studies. There have recently been tremendous breakthroughs in treatment of HIV infections, but challenges still remain. Scarlette Abbou, an engineer at the French National Centre for Scientific Research (CNRS), explained her lab’s work in this field: “CD4 T-cells – among others – act as reservoirs for HIV, and are established during the earliest stage of infection....
Hemp and marijuana are becoming more popular because of legalisation in multiple countries. The increase of this market also increases the offer of products and therefore the need to monitor different components. This application focusses on Residual Solvent analysis but Scion Instruments has an extended portfolio including potency analyses (AN091, 92, 93 and 130) and Terpene analysis (AN133 and 136) Residual Solvents are organic volatile products that are often used for the extraction...
Ziath reports how it has worked with the Hubrecht Institute (Utrecht, Netherlands) which has developed a pioneering automated test robot, called STRIP-1, which can process up to 20,000 samples for SARS-CoV-2 testing in just 24 hours. This makes it much faster than all other automated SARS-CoV-2 testing systems used to date. In addition, all samples can be tracked precisely because they have a 2D-barcode on the bottom of each tube that is scanned multiple times throughout the process....
Research on hunger wins 2021 Eppendorf & Science Prize. The American scientist Amber L. Alhadeff, Ph.D., Principal Investigator at the Monell Chemical Senses Center and the University of Pennsylvania, USA has won the 2021 Eppendorf & Science Prize for Neurobiology for her work on the gut-brain control of hunger circuits. Alhadeff’s research has revealed how hunger-sensitive neurons in the brain receive signals from the gastrointestinal tract, and how they influence food intake and other survival behaviors....
Ubiquigent Limited (Ubiquigent) announces the extension and expansion of its long-term collaboration with Bristol Myers Squibb. Under the terms of the agreement, Ubiquigent will provide Bristol Myers Squibb with increased access to its deubiquitylase (DUB) enzyme inhibitor drug discovery platform to provide further support to additional therapeutic areas...
The new Test Labs infection prevention research and test laboratory in Peterborough, which opened officially in January 2021, has achieved prestigious UKAS accreditation in less than twelve months, one of the fastest awards in the history of the accreditation body. Parent company Inivos created the facility after the Covid pandemic redirected government and commercial laboratories’ focus which stretched their capacity....
Sartorius and Waters will partner to implement the BioAccord™ LC-MS System from Waters as a new bioprocess analyzer with data connectivity to Sartorius’ Ambr® multi-parallel bioreactor systems to deliver mass spectral information on drug substances, related analytes and cell culture media. This combination will greatly accelerate and improve the accuracy and speed of tasks from clone selection to bioprocess optimization...
A UK-based aquaculture business aims to remove billions of tonnes of carbon from the atmosphere each year by growing and harvesting floating seaweed in the Atlantic Ocean. Seafields is developing and testing new technologies focused on growing and capturing Sargassum, a seaweed that has escaped its normal environment in the Sargasso Sea and has exploded in growth in the last two decades...
Blood alcohol analysis is one of a variety of headspace methods performed in forensic toxicology laboratories. The Versa was evaluated to determine its suitability to perform an occasional blood alcohol test. Methanol, acetone, ethanol, isopropanol and acetaldehyde along with n-propanol, a typical internal standard, were tested with the Versa headspace instrument....
Centrifugal Partition Chromatography (CPC) or Counter Current Chromatography (CCC), as it is sometimes known, is a cost-effective solution for natural product purification using liquid-liquid phases rather than a solid stationary phase. With no column to replace or silica to recycle, CPC offers low solvent consumption compared with traditional chromatography techniques and requires no extensive pre-treatment of samples....
VectorBuilder Inc., a global leader in vector design, optimization and GMP manufacturing, and Landau Biotechnology Co., a world leader in developing nonhuman primate (NHP) models for clinical research applications, have signed a strategic partnership that will establish the world’s first primate gene therapy R&D center. The center will build advanced vector screening and optimization platforms to provide unique CRO services to the rapidly growing gene and cell therapy industry....
SCION Instruments has recently published its latest Application Note “Analysis of Fusel Alcohols Using HT3 Headspace Sampling”. Fusel alcohols are a common by-product of the fermentation process, but abnormal quantities or types can indicate alcoholic beverage adulteration. Method SSD: TM:200 is a direct injection method for testing these alcohols. The method states that Non-Beverage Alcohol (NBA) products, not miscible with water, cannot be analyzed by this method....
UK-based HydRegen are using a DrySyn OCTO reaction station from Asynt to help develop a next generation biocatalyst system that enables cleaner, safer, and more efficient chemical manufacture. HydRegen spun-out from the Vincent Group in the Dept. of Chemistry at the University of Oxford in March 2021. They are developing novel and sustainable strategies for using the growing toolbox of NADH-dependent redox biocatalysts in chemical synthesis...