Are you plagued with poor peak shapes, low sensitivities, sample carry over and/or low recoveries for challenging compounds. Several substances are able to interact with the usual inert column hardware materials such as stainless steel or titanium. The adsorption on metallic surfaces typically leads to peak tailing, loss of recovery and sample carry over. Critical substances are especially metal-coordinating compounds, such as fumonisins, sphingophospholipids or organophosphates in general....
Researchers from the University of Birmingham, U.K., have confirmed the speed, accuracy and simplicity of a novel, highly sensitive testing method for COVID-19 that can be deployed at entertainment venues, airport arrival terminals, and in remote settings where clinical testing laboratories are not available. The scientists used a three way comparison study to confirm that the Exponential Amplification Reaction (EXPAR) method is just as sensitive, but faster, than both PCR and LAMP tests...
Recent work by a team of researchers at Queen’s University Belfast and University College London has reported on a newly developed strategy for the manufacture of a high drug loaded amorphous solid dispersion (HDASD) using a hot-melt extrusion (HME) based platform. Around 80% of new drug candidates that emerge are classified as poorly soluble...
A Glasgow University spinout specialising in the next generation of green insecticides has secured seed investment of £1.3 million to support ongoing development of its unique nature-inspired pesticides, the first of their kind to be developed worldwide. Established in May 2020 after four years of research funded by UKRI BBSRC and the EC, and commercialisation support from Scottish Enterprise’s High Growth Spinout Programme, SOLASTA Bio develops environmentally-friendly products that meet a global need for new and effective crop protection...
Thermo Fisher Scientific, the world leader in serving science, and ChromSword, a provider of innovative software products, have collaborated to launch an automated high performance liquid chromatography (HPLC) and ultra-high performance liquid chromatography (UHPLC) method development system that enables chromatographers to deliver robust and validated methods in less time and with higher confidence...
Solvent evaporation specialists - BioChromato Inc. has published an informative web page that describes how Vacuum Vortex Concentration (VVC) methodology enables users of its Smart Series of Evaporators remove even higher boiling solvents including water, DMSO and DMF quickly and safely. At the heart of each BioChromato Smart Evaporator is a highly efficient spiral airflow created by a special concentrator plug or “Spiral Plug”....
Cresset, innovative provider of outstanding software for molecule discovery and design, is pleased to announce that OncoArendi Therapeutics SA (WSE: OAT), a biotechnology company which specializes in the discovery and development of new drugs, has licensed Flare™ for use in its internal development programs. Cresset software uses its proprietary descriptors of shapes and electrostatics to help chemists understand the key interactions that underpin biological activity...
Autoscribe Informatics has released a new veterinary laboratory case study focusing on the benefits that Matrix Gemini LIMS has bought to Scone Equine Hospital. The LIMS is in daily use in the largest equine veterinary practice in Australia. Explaining why Scone Equine chose Matrix Gemini LIMS the laboratory supervisor said “We ended up deciding on Matrix due to the flexibility that the system offered...
IDEXX has welcomed the publication of a study carried out by the Public Health Laboratory of L'Hospitalet in Barcelona, Spain, which compared the IDEXX Legiolert® test with the standard method for detection and enumeration of Legionella (ISO 11731). Comparing the methods in both potable and non-potable water samples according to the rigorous ISO 17994 protocol, the study found that Legiolert detected more positive results than ISO 11731 and was statistically more sensitive for Legionella pneumophila....
OGT™, A Sysmex Group Company, has revealed the expansion of support activities with CytoCell® University – an initiative that promises to partner with scientists to provide innovative and expert training on the basics of fluorescence in situ hybridisation (FISH). CytoCell University’s FISH training reaffirms OGT’s mission to support scientists around the globe and help customers advance genetic analysis.
To protect consumers and patients, the filling weight of finished goods and drugs must be checked gravimetrically. Uniformity of dosage unit measurements ensure that the mean weight meets the specified nominal package contents and is within permissible tolerances in order to avoid over- and underdosing. Average weight control prevents underfilling of prepacked goods...
Illumina, Inc. has donated $1 million in sequencing capabilities to the Molecular Diagnostic Reference Laboratory at Kasturba Hospital, in the Municipal Corporate of Greater Mumbai, to help expand SARS-CoV-2 sequencing capabilities in the region and support the broader genomic surveillance effort across India. Kasturba Hospital was the first hospital in Mumbai to begin sequencing SARS-CoV-2 this year and will examine how variants of the virus are being spread across India....
Academics in search of solutions to creating more energy efficient phones and television screens now have high-performance machinery at their fingertips, after Northumbria University has invested in a suite of new state-of-the-art equipment to push its leading-edge research forward. Investment in a Fluorescence Spectrometer, which has now been installed in a lab within Northumbria’s department of Mathematics, Physics and Electrical Engineering, will further research led by Dr Marc Etherington
A new approach to tackling the spread of malaria in sub-Saharan Africa, which combines affordable, easy-to-administer blood tests with machine learning and unbreakable encryption, has generated encouraging early results in Uganda. Malaria is one of the world's leading causes of illness and death, sickening around 228 million people each year, more than 400,000 of them fatally. Like COVID-19, malaria can spread asymptomatically, making widespread field testing vital to containing outbreaks and saving lives. ...
We spoke to scientists who are spending their careers trying to unlock the secrets and possibilities of cell research. Watch Heather read her incredible love letter as we begin our journey to explore the amazing connection between scientists and cells. Heather’s research sets out to uncover key indicators that will allow physicians to detect bone metastasis in breast cancer patients, allowing for greater survival rates....
Eli Lilly and Company and their industry partners, including sample management specialists – Ziath, are speeding the discovery of new medicines through the fully automated Lilly Life Sciences Studio (L2S2) lab in San Diego, USA. L2S2 was set up as part of the Lilly Discovery Automation Research and Technologies Group. The lab has brought together a team of talented automation engineers and scientists in the design, implementation, and operation of a variety of innovative automation projects which are introduced in an informative video...
HORIBA UK announces the first UK installation of its Fluorolog-QM modular research-grade fluorescence spectrometer, the world’s highest-performance fluorescence analyser. The spectrometer will form an integral part of research into novel fluorophores by Dr Marc Etherington of Northumbria University (Newcastle, UK). His team is opening up new scientific understanding of fluorophores in order to offer light-based solutions to real-world issues, including the development of new materials to reduce the energy consumption of household devices....
Nanopharm Ltd., an Aptar Pharma company and leader in contract research and development of orally inhaled and nasally delivered drug products (OINDP) and Leyden Labs, a company targeting commonalities of viral families to protect humanity from known and future viruses, have announced that they have entered into an agreement to develop nasal sprays that may provide broad protection against respiratory viruses...
PharmEnable, an AI drug discovery company unlocking challenging biological targets, announces that it has entered into a drug discovery collaboration with LifeArc, an independent UK medical research charity, to apply their respective technologies and expertise to discover novel oral antiviral drugs with activity against coronaviruses....
At the start of the COVID-19 pandemic in March 2020, Dr Mason and his team set about turning their knowledge of functional genomics to sequencing and understanding the clinical impact of the SARS-CoV-2 virus. The lab developed multiple methods to detect infections, track strain evolution, and identify biomarkers of disease course to assist with clinical identification and treatment....
Agilent Technologies Inc., has announced the availability of an optimized and verified eMethod for PFAS Analysis in Water by LC/TQ for testing per- and polyfluoroalkyl substances (PFAS) in drinking and surface water using liquid chromatography and mass spectrometry. PFAS—known as ‘Forever Chemicals’—are a group of man-made chemicals that include PFOA, PFOS, GenX, and many others....
Researchers at Queen's University Belfast are using microfluidics to fabricate particles for the encapsulation of drugs and biologics for imaging, treatment and cell targeting. Dr Dimitrios Lamprou, a Reader in Pharmaceutical Engineering at the School of Pharmacy, explained: “Our work involves the microfluidic preparation of lipid (liposome) and polymer-based (PLGA) nanoparticles that can efficiently encapsulate cancer drugs...
Are you plagued with poor peak shapes, low sensitivities, sample carry over and/or low recoveries for challenging compounds. Several substances are able to interact with the usual inert column hardware materials such as stainless steel or titanium. The adsorption on metallic surfaces typically leads to peak tailing, loss of recovery and sample carry over. Critical substances are especially metal-coordinating compounds, such as fumonisins, sphingophospholipids or organophosphates in general....
Researchers from the University of Birmingham, U.K., have confirmed the speed, accuracy and simplicity of a novel, highly sensitive testing method for COVID-19 that can be deployed at entertainment venues, airport arrival terminals, and in remote settings where clinical testing laboratories are not available. The scientists used a three way comparison study to confirm that the Exponential Amplification Reaction (EXPAR) method is just as sensitive, but faster, than both PCR and LAMP tests... 
Recent work by a team of researchers at Queen’s University Belfast and University College London has reported on a newly developed strategy for the manufacture of a high drug loaded amorphous solid dispersion (HDASD) using a hot-melt extrusion (HME) based platform. Around 80% of new drug candidates that emerge are classified as poorly soluble...
A Glasgow University spinout specialising in the next generation of green insecticides has secured seed investment of £1.3 million to support ongoing development of its unique nature-inspired pesticides, the first of their kind to be developed worldwide. Established in May 2020 after four years of research funded by UKRI BBSRC and the EC, and commercialisation support from Scottish Enterprise’s High Growth Spinout Programme, SOLASTA Bio develops environmentally-friendly products that meet a global need for new and effective crop protection...
Thermo Fisher Scientific, the world leader in serving science, and ChromSword, a provider of innovative software products, have collaborated to launch an automated high performance liquid chromatography (HPLC) and ultra-high performance liquid chromatography (UHPLC) method development system that enables chromatographers to deliver robust and validated methods in less time and with higher confidence...
Solvent evaporation specialists - BioChromato Inc. has published an informative web page that describes how Vacuum Vortex Concentration (VVC) methodology enables users of its Smart Series of Evaporators remove even higher boiling solvents including water, DMSO and DMF quickly and safely. At the heart of each BioChromato Smart Evaporator is a highly efficient spiral airflow created by a special concentrator plug or “Spiral Plug”....
Cresset, innovative provider of outstanding software for molecule discovery and design, is pleased to announce that OncoArendi Therapeutics SA (WSE: OAT), a biotechnology company which specializes in the discovery and development of new drugs, has licensed Flare™ for use in its internal development programs. Cresset software uses its proprietary descriptors of shapes and electrostatics to help chemists understand the key interactions that underpin biological activity...
Autoscribe Informatics has released a new veterinary laboratory case study focusing on the benefits that Matrix Gemini LIMS has bought to Scone Equine Hospital. The LIMS is in daily use in the largest equine veterinary practice in Australia. Explaining why Scone Equine chose Matrix Gemini LIMS the laboratory supervisor said “We ended up deciding on Matrix due to the flexibility that the system offered...
IDEXX has welcomed the publication of a study carried out by the Public Health Laboratory of L'Hospitalet in Barcelona, Spain, which compared the IDEXX Legiolert® test with the standard method for detection and enumeration of Legionella (ISO 11731). Comparing the methods in both potable and non-potable water samples according to the rigorous ISO 17994 protocol, the study found that Legiolert detected more positive results than ISO 11731 and was statistically more sensitive for Legionella pneumophila....
OGT™, A Sysmex Group Company, has revealed the expansion of support activities with CytoCell® University – an initiative that promises to partner with scientists to provide innovative and expert training on the basics of fluorescence in situ hybridisation (FISH). CytoCell University’s FISH training reaffirms OGT’s mission to support scientists around the globe and help customers advance genetic analysis.
To protect consumers and patients, the filling weight of finished goods and drugs must be checked gravimetrically. Uniformity of dosage unit measurements ensure that the mean weight meets the specified nominal package contents and is within permissible tolerances in order to avoid over- and underdosing. Average weight control prevents underfilling of prepacked goods...
Illumina, Inc. has donated $1 million in sequencing capabilities to the Molecular Diagnostic Reference Laboratory at Kasturba Hospital, in the Municipal Corporate of Greater Mumbai, to help expand SARS-CoV-2 sequencing capabilities in the region and support the broader genomic surveillance effort across India. Kasturba Hospital was the first hospital in Mumbai to begin sequencing SARS-CoV-2 this year and will examine how variants of the virus are being spread across India....
Academics in search of solutions to creating more energy efficient phones and television screens now have high-performance machinery at their fingertips, after Northumbria University has invested in a suite of new state-of-the-art equipment to push its leading-edge research forward. Investment in a Fluorescence Spectrometer, which has now been installed in a lab within Northumbria’s department of Mathematics, Physics and Electrical Engineering, will further research led by Dr Marc Etherington
A new approach to tackling the spread of malaria in sub-Saharan Africa, which combines affordable, easy-to-administer blood tests with machine learning and unbreakable encryption, has generated encouraging early results in Uganda. Malaria is one of the world's leading causes of illness and death, sickening around 228 million people each year, more than 400,000 of them fatally. Like COVID-19, malaria can spread asymptomatically, making widespread field testing vital to containing outbreaks and saving lives. ...
We spoke to scientists who are spending their careers trying to unlock the secrets and possibilities of cell research. Watch Heather read her incredible love letter as we begin our journey to explore the amazing connection between scientists and cells. Heather’s research sets out to uncover key indicators that will allow physicians to detect bone metastasis in breast cancer patients, allowing for greater survival rates....
Eli Lilly and Company and their industry partners, including sample management specialists – Ziath, are speeding the discovery of new medicines through the fully automated Lilly Life Sciences Studio (L2S2) lab in San Diego, USA. L2S2 was set up as part of the Lilly Discovery Automation Research and Technologies Group. The lab has brought together a team of talented automation engineers and scientists in the design, implementation, and operation of a variety of innovative automation projects which are introduced in an informative video...
HORIBA UK announces the first UK installation of its Fluorolog-QM modular research-grade fluorescence spectrometer, the world’s highest-performance fluorescence analyser. The spectrometer will form an integral part of research into novel fluorophores by Dr Marc Etherington of Northumbria University (Newcastle, UK). His team is opening up new scientific understanding of fluorophores in order to offer light-based solutions to real-world issues, including the development of new materials to reduce the energy consumption of household devices....
Nanopharm Ltd., an Aptar Pharma company and leader in contract research and development of orally inhaled and nasally delivered drug products (OINDP) and Leyden Labs, a company targeting commonalities of viral families to protect humanity from known and future viruses, have announced that they have entered into an agreement to develop nasal sprays that may provide broad protection against respiratory viruses...
PharmEnable, an AI drug discovery company unlocking challenging biological targets, announces that it has entered into a drug discovery collaboration with LifeArc, an independent UK medical research charity, to apply their respective technologies and expertise to discover novel oral antiviral drugs with activity against coronaviruses....
At the start of the COVID-19 pandemic in March 2020, Dr Mason and his team set about turning their knowledge of functional genomics to sequencing and understanding the clinical impact of the SARS-CoV-2 virus. The lab developed multiple methods to detect infections, track strain evolution, and identify biomarkers of disease course to assist with clinical identification and treatment....
Agilent Technologies Inc., has announced the availability of an optimized and verified eMethod for PFAS Analysis in Water by LC/TQ for testing per- and polyfluoroalkyl substances (PFAS) in drinking and surface water using liquid chromatography and mass spectrometry. PFAS—known as ‘Forever Chemicals’—are a group of man-made chemicals that include PFOA, PFOS, GenX, and many others....
Researchers at Queen's University Belfast are using microfluidics to fabricate particles for the encapsulation of drugs and biologics for imaging, treatment and cell targeting. Dr Dimitrios Lamprou, a Reader in Pharmaceutical Engineering at the School of Pharmacy, explained: “Our work involves the microfluidic preparation of lipid (liposome) and polymer-based (PLGA) nanoparticles that can efficiently encapsulate cancer drugs...