INTEGRA Biosciences provides an extensive range of multichannel and electronic pipettes – as well as robotic-assisted platforms – to help increase the throughput of your cell culture workflows. Switching to electronic pipettes or automated systems has been proven to offer significant advantages over manual processes, providing reproducible results with fewer handling errors, while eliminating the painstaking work of repetitive liquid handling....
Novel Concepts Medical, founded by Rachel Alkalay, PhD, and based in Tel Aviv, is delighted to announce the successful testing of its plant-based formulations for the treatment of SARS-CoV-2, the virus responsible for the COVID-19 pandemic. The testing methodology was devised by Dr. Alkalay, who is the inventor of these formulations. The testing, led by Tracey Campbell, PhD, was carried out by the Centre for Microbial Chemical Biology at the Michael G. DeGroote Institute for Infectious Disease Research at McMaster University...
40 senior people working across UK labs were surveyed by Automata on their current challenges and views. The poll identified that automation is seen as a solution to relieve existing pressures, improve day-to-day capacity and turnaround time, reduce human error and ultimately enhance patient outcomes. Respondents worked across pathology (60%) and diagnostics (38%), with the vast majority (93%) of those questioned undertaking NHS work...
In this article Jason Myers, PhD, CEO at Genapsys discusses the benefits of automating components of NGS workflows as well as some tips for evaluating approaches to automation in labs of any size. Additionally, it will share the implications of automation for the future of NGS-based diagnostics and its role in bringing valuable health insights to more patients than ever...
Metrion Biosciences Limited (“Metrion”), the specialist ion channel contract research and drug discovery company, has announced it has expanded its capabilities and expertise through the addition of automated low volume liquid handling capability and 384-well electrophysiology and fluorescence-based high throughput screening (HTS) assay systems. In the newly created position of Head of Screening Technologies, Dr Gary Clark will lead the implementation...
With chemists engineering new “designer drugs” everyday, law enforcement and regulatory bodies need testing to quickly and accurately determine the composition of these compounds. This study will present a static headspace method for rapidly determining drug components for use in forensic applications. A HT3 Headspace Analyzer will be used to examine bath salt samples for the presence of mephedrone (MPD) and methylenedioxypyrovalerone (MPDV or MDPK) by GC/MS.
FUJIFILM Irvine Scientific, Inc., a world leader in the development and manufacture of serum-free and chemically defined cell culture media for bioproduction and cell therapy manufacturing, has announced the establishment of an Innovation and Collaboration Center in Suzhou New District, China. Through this new center, experts will collaborate with customers to design upstream cell culture processes that meet their biomanufacturing needs...
BioChromato Inc. has published an interview that describes a new bioremediation technique developed by a leading Environmental Research Center and how the Smart Evaporator C1 offers a productive tool for preparing microbial degradation culture media for analysis. The novel bioremediation technique, based upon patented degrading microorganisms impregnated on carbonized wood, has been demonstrated to detoxify persistent organic pollutants (POPs) that cannot be decomposed by natural processes in soil.
A diffraction grating is used to separate polychromatic light into its constituent wavelengths. In a Raman spectrometer diffraction gratings are used to separate the constituent wavelengths of the collected Raman scatter onto different pixels of the CCD camera for detection. All Raman spectrometers will require at least one diffraction grating and will frequently be configured to contain more than one to allow the user optimum grating selection for their samples and excitation wavelength(s).
YMC-Triart C18 UHPLC columns with an ID of 1 mm are the ideal choice for high sensitivity LC/MS analyses. In this new application note, the screening of 6 antineoplastic drugs is shown. This analysis requires the highest sensitivity since even the smallest amounts of these drugs need to be detected due to their adverse very serious, life-threatening effects. By choosing a high efficiency column with a small internal diameter of 1 mm and coupling it to mass spectrometry the benefit becomes clear: excellent peak shapes – also for low sensitivity compounds!
MolGen B.V. is grounded in its history of developing and marketing advanced bulk chemistry kits for DNA/RNA extraction that successfully satisfied the needs of seed and plant breeding, MolGen today remains committed to finding new ways to advance how it helps those who work in agriculture laboratories. Based in The Netherlands, leveraging from a knowledgeable environment, MolGen has grown in just a few short years and now offers agriculture partners of all sizes a wide range of chemistry tools...
INTEGRA’s automated pipetting solutions are helping scientists meet the challenge of efficiently pooling potentially infectious samples prior to testing for disease surveillance and diagnostics, increasing throughput and accelerating time to results. Pooling of patient samples is commonly used in immunoassays and molecular diagnostics to increase testing capacity while reducing reagent costs for the analysis of SARS-CoV-2 and other infectious agents....
NovAliX, a Contract Research Organization (CRO) specializing in drug research and development, announces its partnership with Sanofi for the development of new DNA-Encoded Libraries (DELs). This multi-year agreement will see the partners join forces to design both general and focused chemical libraries, and carry out screening activities to identify new and useful chemical structures...
Asynt reports upon a new paper, written by a multidisciplinary team of experts at the Institute for Process Research and Chemistry (iRPD) at the University of Leeds (UK), that describes how the fReactor flow chemistry system with add-on photochemical flow modules improves synthetic reactions commonly used in the preparation of drug intermediates. In contrast to many tubular or plate-based flow chemistry systems, the Asynt fReactor with Photo Flow modules is especially well-suited...
The results of Olympus’ ongoing joint research program to create an AI-based pathology diagnostic tool with the potential to streamline pathologists’ workloads were announced at the Japan Society of Digital Pathology Study annual meeting. The diagnostic tool achieved 100% sensitivity and 50% or more specificity for all gastric biopsy pathology specimens analyzed...
Moderna, Inc., a biotechnology company pioneering messenger RNA (mRNA) therapeutics and vaccines, has announced updates to its strategy to address SARS-CoV-2 variants of concern, given the emergence of the B.1.1.529 (Omicron) variant. The recently described Omicron variant includes mutations seen in the Delta variant that are believed to increase transmissibility and mutations seen in the Beta and Delta variants that are believed to promote immune escape....
A recent article published in mBio (American Society for Microbiology) illustrates how the cVLP vaccine developed by AdaptVac and University of Copenhagen has successfully been produced using a robust production platform providing scalability, low cost, and safety. Attana technology has been applied by the team of Prof Ali Salanti at the University of Copenhagen in their development of a COVID-19 vaccine based on the patented Capsid Virus-Like Particle (cVLP) technology...
Accelerated Technology Laboratories, Inc. (ATL), a leader in Laboratory Information Management Systems (LIMS), wraps up the 2021 LIMS Webcast Series on Wednesday, December 8th with Using a LIMS to Streamline Your Quality Management System (QMS) and Document Handling Procedures. For most laboratories, the Quality Management System (QMS) creates efficient processes, helps to meet regulatory and quality program requirements, and ensures customer satisfaction...
The use of only one SEC column brings a certain limitation due to its dedicated pore size and a limited column volume. By coupling two columns this hurdle can be overcome. Doubling the column length implies a doubled column volume which results in improved resolution of peaks. Additionally, if using two columns with different pore size, the applicable molecular weight range can be increased significantly....
UK medical research charity LifeArc announces its commitment to spend up to £1.3 billion by 2030 to help deliver new diagnostics, drugs, devices and digital solutions that transform the way diseases such as motor neurone disease are prevented, identified and treated. LifeArc plans to double its average annual spend, over the period to 2030. And the charity aims to leverage additional money, skills and resource from others to multiply the impact they can have for patients, together...
The Pistoia Alliance, a global, not-for-profit alliance that advocates for greater collaboration in life sciences R&D, has today outlined predictions for the life sciences industry in 2022. The predictions come from three experts recently appointed by the Alliance to drive collaboration efforts across its three key themes. Their insights span the urgent fights against antimicrobial resistance, the potential of quantum computing and commercial space travel, and autonomous laboratories.
A Schlenk Line is a tubular glass apparatus commonly used in chemistry or material laboratory research to carry out experiments under a vacuum and an inert atmosphere (like nitrogen or argon). It is used when samples are sensitive to air/moisture and the vacuum is also often used to remove the last traces of solvent from a sample. A Schlenk Line typically contains a dual glass manifold with multiple ports; the number of ports is configurable....
INTEGRA Biosciences provides an extensive range of multichannel and electronic pipettes – as well as robotic-assisted platforms – to help increase the throughput of your cell culture workflows. Switching to electronic pipettes or automated systems has been proven to offer significant advantages over manual processes, providing reproducible results with fewer handling errors, while eliminating the painstaking work of repetitive liquid handling....
Novel Concepts Medical, founded by Rachel Alkalay, PhD, and based in Tel Aviv, is delighted to announce the successful testing of its plant-based formulations for the treatment of SARS-CoV-2, the virus responsible for the COVID-19 pandemic. The testing methodology was devised by Dr. Alkalay, who is the inventor of these formulations. The testing, led by Tracey Campbell, PhD, was carried out by the Centre for Microbial Chemical Biology at the Michael G. DeGroote Institute for Infectious Disease Research at McMaster University...
40 senior people working across UK labs were surveyed by Automata on their current challenges and views. The poll identified that automation is seen as a solution to relieve existing pressures, improve day-to-day capacity and turnaround time, reduce human error and ultimately enhance patient outcomes. Respondents worked across pathology (60%) and diagnostics (38%), with the vast majority (93%) of those questioned undertaking NHS work...
In this article 
Metrion Biosciences Limited (“Metrion”), the specialist ion channel contract research and drug discovery company, has announced it has expanded its capabilities and expertise through the addition of automated low volume liquid handling capability and 384-well electrophysiology and fluorescence-based high throughput screening (HTS) assay systems. In the newly created position of Head of Screening Technologies, Dr Gary Clark will lead the implementation...
With chemists engineering new “designer drugs” everyday, law enforcement and regulatory bodies need testing to quickly and accurately determine the composition of these compounds. This study will present a static headspace method for rapidly determining drug components for use in forensic applications. A HT3 Headspace Analyzer will be used to examine bath salt samples for the presence of mephedrone (MPD) and methylenedioxypyrovalerone (MPDV or MDPK) by GC/MS.
FUJIFILM Irvine Scientific, Inc., a world leader in the development and manufacture of serum-free and chemically defined cell culture media for bioproduction and cell therapy manufacturing, has announced the establishment of an Innovation and Collaboration Center in Suzhou New District, China. Through this new center, experts will collaborate with customers to design upstream cell culture processes that meet their biomanufacturing needs...
BioChromato Inc. has published an interview that describes a new bioremediation technique developed by a leading Environmental Research Center and how the Smart Evaporator C1 offers a productive tool for preparing microbial degradation culture media for analysis. The novel bioremediation technique, based upon patented degrading microorganisms impregnated on carbonized wood, has been demonstrated to detoxify persistent organic pollutants (POPs) that cannot be decomposed by natural processes in soil.
A diffraction grating is used to separate polychromatic light into its constituent wavelengths. In a Raman spectrometer diffraction gratings are used to separate the constituent wavelengths of the collected Raman scatter onto different pixels of the CCD camera for detection. All Raman spectrometers will require at least one diffraction grating and will frequently be configured to contain more than one to allow the user optimum grating selection for their samples and excitation wavelength(s).
YMC-Triart C18 UHPLC columns with an ID of 1 mm are the ideal choice for high sensitivity LC/MS analyses. In this new application note, the screening of 6 antineoplastic drugs is shown. This analysis requires the highest sensitivity since even the smallest amounts of these drugs need to be detected due to their adverse very serious, life-threatening effects. By choosing a high efficiency column with a small internal diameter of 1 mm and coupling it to mass spectrometry the benefit becomes clear: excellent peak shapes – also for low sensitivity compounds!
MolGen B.V. is grounded in its history of developing and marketing advanced bulk chemistry kits for DNA/RNA extraction that successfully satisfied the needs of seed and plant breeding, MolGen today remains committed to finding new ways to advance how it helps those who work in agriculture laboratories. Based in The Netherlands, leveraging from a knowledgeable environment, MolGen has grown in just a few short years and now offers agriculture partners of all sizes a wide range of chemistry tools...
INTEGRA’s automated pipetting solutions are helping scientists meet the challenge of efficiently pooling potentially infectious samples prior to testing for disease surveillance and diagnostics, increasing throughput and accelerating time to results. Pooling of patient samples is commonly used in immunoassays and molecular diagnostics to increase testing capacity while reducing reagent costs for the analysis of SARS-CoV-2 and other infectious agents....
NovAliX, a Contract Research Organization (CRO) specializing in drug research and development, announces its partnership with Sanofi for the development of new DNA-Encoded Libraries (DELs). This multi-year agreement will see the partners join forces to design both general and focused chemical libraries, and carry out screening activities to identify new and useful chemical structures...
Asynt reports upon a new paper, written by a multidisciplinary team of experts at the Institute for Process Research and Chemistry (iRPD) at the University of Leeds (UK), that describes how the fReactor flow chemistry system with add-on photochemical flow modules improves synthetic reactions commonly used in the preparation of drug intermediates. In contrast to many tubular or plate-based flow chemistry systems, the Asynt fReactor with Photo Flow modules is especially well-suited...
The results of Olympus’ ongoing joint research program to create an AI-based pathology diagnostic tool with the potential to streamline pathologists’ workloads were announced at the Japan Society of Digital Pathology Study annual meeting. The diagnostic tool achieved 100% sensitivity and 50% or more specificity for all gastric biopsy pathology specimens analyzed...
Moderna, Inc., a biotechnology company pioneering messenger RNA (mRNA) therapeutics and vaccines, has announced updates to its strategy to address SARS-CoV-2 variants of concern, given the emergence of the B.1.1.529 (Omicron) variant. The recently described Omicron variant includes mutations seen in the Delta variant that are believed to increase transmissibility and mutations seen in the Beta and Delta variants that are believed to promote immune escape....
A recent article published in mBio (American Society for Microbiology) illustrates how the cVLP vaccine developed by AdaptVac and University of Copenhagen has successfully been produced using a robust production platform providing scalability, low cost, and safety. Attana technology has been applied by the team of Prof Ali Salanti at the University of Copenhagen in their development of a COVID-19 vaccine based on the patented Capsid Virus-Like Particle (cVLP) technology...
Accelerated Technology Laboratories, Inc. (ATL), a leader in Laboratory Information Management Systems (LIMS), wraps up the 2021 LIMS Webcast Series on Wednesday, December 8th with Using a LIMS to Streamline Your Quality Management System (QMS) and Document Handling Procedures. For most laboratories, the Quality Management System (QMS) creates efficient processes, helps to meet regulatory and quality program requirements, and ensures customer satisfaction...
The use of only one SEC column brings a certain limitation due to its dedicated pore size and a limited column volume. By coupling two columns this hurdle can be overcome. Doubling the column length implies a doubled column volume which results in improved resolution of peaks. Additionally, if using two columns with different pore size, the applicable molecular weight range can be increased significantly....
UK medical research charity LifeArc announces its commitment to spend up to £1.3 billion by 2030 to help deliver new diagnostics, drugs, devices and digital solutions that transform the way diseases such as motor neurone disease are prevented, identified and treated. LifeArc plans to double its average annual spend, over the period to 2030. And the charity aims to leverage additional money, skills and resource from others to multiply the impact they can have for patients, together...
The Pistoia Alliance, a global, not-for-profit alliance that advocates for greater collaboration in life sciences R&D, has today outlined predictions for the life sciences industry in 2022. The predictions come from three experts recently appointed by the Alliance to drive collaboration efforts across its three key themes. Their insights span the urgent fights against antimicrobial resistance, the potential of quantum computing and commercial space travel, and autonomous laboratories.
A Schlenk Line is a tubular glass apparatus commonly used in chemistry or material laboratory research to carry out experiments under a vacuum and an inert atmosphere (like nitrogen or argon). It is used when samples are sensitive to air/moisture and the vacuum is also often used to remove the last traces of solvent from a sample. A Schlenk Line typically contains a dual glass manifold with multiple ports; the number of ports is configurable....