NovAliX, a Contract Research Organization (CRO) specializing in drug research and development, announces its partnership with Sanofi for the development of new DNA-Encoded Libraries (DELs). This multi-year agreement will see the partners join forces to design both general and focused chemical libraries, and carry out screening activities to identify new and useful chemical structures...
Asynt reports upon a new paper, written by a multidisciplinary team of experts at the Institute for Process Research and Chemistry (iRPD) at the University of Leeds (UK), that describes how the fReactor flow chemistry system with add-on photochemical flow modules improves synthetic reactions commonly used in the preparation of drug intermediates. In contrast to many tubular or plate-based flow chemistry systems, the Asynt fReactor with Photo Flow modules is especially well-suited...
The results of Olympus’ ongoing joint research program to create an AI-based pathology diagnostic tool with the potential to streamline pathologists’ workloads were announced at the Japan Society of Digital Pathology Study annual meeting. The diagnostic tool achieved 100% sensitivity and 50% or more specificity for all gastric biopsy pathology specimens analyzed...
Moderna, Inc., a biotechnology company pioneering messenger RNA (mRNA) therapeutics and vaccines, has announced updates to its strategy to address SARS-CoV-2 variants of concern, given the emergence of the B.1.1.529 (Omicron) variant. The recently described Omicron variant includes mutations seen in the Delta variant that are believed to increase transmissibility and mutations seen in the Beta and Delta variants that are believed to promote immune escape....
A recent article published in mBio (American Society for Microbiology) illustrates how the cVLP vaccine developed by AdaptVac and University of Copenhagen has successfully been produced using a robust production platform providing scalability, low cost, and safety. Attana technology has been applied by the team of Prof Ali Salanti at the University of Copenhagen in their development of a COVID-19 vaccine based on the patented Capsid Virus-Like Particle (cVLP) technology...
Accelerated Technology Laboratories, Inc. (ATL), a leader in Laboratory Information Management Systems (LIMS), wraps up the 2021 LIMS Webcast Series on Wednesday, December 8th with Using a LIMS to Streamline Your Quality Management System (QMS) and Document Handling Procedures. For most laboratories, the Quality Management System (QMS) creates efficient processes, helps to meet regulatory and quality program requirements, and ensures customer satisfaction...
The use of only one SEC column brings a certain limitation due to its dedicated pore size and a limited column volume. By coupling two columns this hurdle can be overcome. Doubling the column length implies a doubled column volume which results in improved resolution of peaks. Additionally, if using two columns with different pore size, the applicable molecular weight range can be increased significantly....
UK medical research charity LifeArc announces its commitment to spend up to £1.3 billion by 2030 to help deliver new diagnostics, drugs, devices and digital solutions that transform the way diseases such as motor neurone disease are prevented, identified and treated. LifeArc plans to double its average annual spend, over the period to 2030. And the charity aims to leverage additional money, skills and resource from others to multiply the impact they can have for patients, together...
The Pistoia Alliance, a global, not-for-profit alliance that advocates for greater collaboration in life sciences R&D, has today outlined predictions for the life sciences industry in 2022. The predictions come from three experts recently appointed by the Alliance to drive collaboration efforts across its three key themes. Their insights span the urgent fights against antimicrobial resistance, the potential of quantum computing and commercial space travel, and autonomous laboratories.
A Schlenk Line is a tubular glass apparatus commonly used in chemistry or material laboratory research to carry out experiments under a vacuum and an inert atmosphere (like nitrogen or argon). It is used when samples are sensitive to air/moisture and the vacuum is also often used to remove the last traces of solvent from a sample. A Schlenk Line typically contains a dual glass manifold with multiple ports; the number of ports is configurable....
Porvair Sciences has published an in-depth application report demonstrating how their Microlute® CP Reverse Phase Solid Phase Extraction (SPE) microplates provide a robust and highly reproducible SPE LC-MS sample preparation methodology for a range of neutral, acidic, and basic analytes. As a sample preparation method - Solid Phase Extraction is widely acknowledged as a 'go to' tool for the clean-up of samples before analysis by hyphenated techniques such as LC/MS or GC/MS...
INTEGRA Biosciences – a leading provider of high quality laboratory equipment – supplies a comprehensive range of liquid handling tools that are ideal for sterile cell biology workflows. Each piece of equipment, from electronic pipettes to robotic pipetting systems and media dispensers, has been expertly designed to fit comfortably under a laminar flow hood to reduce the risk of cell culture contamination....
Merck, a leading science and technology company, has unveiled a representative study on scientific research productivity. Research productivity is defined in this study as the ratio of measurable input (e.g. number of researchers, financial investment) to measurable output (e.g. patents, publications). The study identified four factors that impact on research productivity in organizations worldwide...
Pharmaceutical solutions provider Pharmidex Pharmaceutical Services Ltd has massively increased its testing capacity with the help of a hire purchase solution from Siemens Financial Services (SFS). Founded in 2002, Pharmidex is a Contract Research Organisation (CRO) that provides high-quality bespoke experimental data to support drug discovery and development. Following its Medicines and Healthcare products Regulatory Agency (MHRA) accreditation, the company wanted to invest in the best possible technology to pursue its research...
(Education and Skills Funding Agency) assessment and has been successful in their application to the RoATP (Register of Apprenticeship Training Providers) to deliver apprenticeships to train the lab technicians and scientists of the future. This will help bridge the huge skills shortage of lab technicians and scientists across the UK....
CN Bio, a leading Organ-on-a-chip Company (OOC) that designs and manufactures single- and multi-organ microphysiological systems (MPS), has announced a research collaboration with the Infection Innovation Consortium (iiCON), a global collaborative infectious disease R&D programme, to validate the next generation of COVID-19 research tools. iiCON’s £174 million programme brings together industry, academia, and clinicians to accelerate the discovery, development...
A promising new approach to potentially treat Alzheimer’s disease – and also vaccinate against it – has been developed by a team of UK and German scientists. Both the antibody-based treatment and the protein-based vaccine developed by the team reduced Alzheimer’s symptoms in mouse models of the disease. The research is published in Molecular Psychiatry. The work is a collaboration between researchers at the University of Leicester, the University Medical Center Göttingen and the medical research charity LifeArc....
Eppendorf Lab Channel is a virtual platform where anyone can watch live and on-demand webinars for free, along with new product and application demonstrations. Peek over the shoulders of Eppendorf experts and let the details and insights illuminate the lab world. Attendees are encouraged to ask questions, interact with the experts, and gain new experiences up close and live....
Guardant Health, Inc. (Nasdaq: GH), a leading precision oncology company, and The Royal Marsden NHS Foundation Trust, one of the United Kingdom’s (UK) leading cancer research organizations, have agreed to enter into a partnership to establish an in-house liquid biopsy testing service using Guardant Health’s industry-leading proprietary digital sequencing platform....
INTEGRA’s VOYAGER adjustable tip spacing pipette is supporting crucial experimental work in longitudinal HIV studies. There have recently been tremendous breakthroughs in treatment of HIV infections, but challenges still remain. Scarlette Abbou, an engineer at the French National Centre for Scientific Research (CNRS), explained her lab’s work in this field: “CD4 T-cells – among others – act as reservoirs for HIV, and are established during the earliest stage of infection....
Hemp and marijuana are becoming more popular because of legalisation in multiple countries. The increase of this market also increases the offer of products and therefore the need to monitor different components. This application focusses on Residual Solvent analysis but Scion Instruments has an extended portfolio including potency analyses (AN091, 92, 93 and 130) and Terpene analysis (AN133 and 136) Residual Solvents are organic volatile products that are often used for the extraction...
Ziath reports how it has worked with the Hubrecht Institute (Utrecht, Netherlands) which has developed a pioneering automated test robot, called STRIP-1, which can process up to 20,000 samples for SARS-CoV-2 testing in just 24 hours. This makes it much faster than all other automated SARS-CoV-2 testing systems used to date. In addition, all samples can be tracked precisely because they have a 2D-barcode on the bottom of each tube that is scanned multiple times throughout the process....
NovAliX, a Contract Research Organization (CRO) specializing in drug research and development, announces its partnership with Sanofi for the development of new DNA-Encoded Libraries (DELs). This multi-year agreement will see the partners join forces to design both general and focused chemical libraries, and carry out screening activities to identify new and useful chemical structures...
Asynt reports upon a new paper, written by a multidisciplinary team of experts at the Institute for Process Research and Chemistry (iRPD) at the University of Leeds (UK), that describes how the fReactor flow chemistry system with add-on photochemical flow modules improves synthetic reactions commonly used in the preparation of drug intermediates. In contrast to many tubular or plate-based flow chemistry systems, the Asynt fReactor with Photo Flow modules is especially well-suited...
The results of Olympus’ ongoing joint research program to create an AI-based pathology diagnostic tool with the potential to streamline pathologists’ workloads were announced at the Japan Society of Digital Pathology Study annual meeting. The diagnostic tool achieved 100% sensitivity and 50% or more specificity for all gastric biopsy pathology specimens analyzed...
Moderna, Inc., a biotechnology company pioneering messenger RNA (mRNA) therapeutics and vaccines, has announced updates to its strategy to address SARS-CoV-2 variants of concern, given the emergence of the B.1.1.529 (Omicron) variant. The recently described Omicron variant includes mutations seen in the Delta variant that are believed to increase transmissibility and mutations seen in the Beta and Delta variants that are believed to promote immune escape....
A recent article published in mBio (American Society for Microbiology) illustrates how the cVLP vaccine developed by AdaptVac and University of Copenhagen has successfully been produced using a robust production platform providing scalability, low cost, and safety. Attana technology has been applied by the team of Prof Ali Salanti at the University of Copenhagen in their development of a COVID-19 vaccine based on the patented Capsid Virus-Like Particle (cVLP) technology...
Accelerated Technology Laboratories, Inc. (ATL), a leader in Laboratory Information Management Systems (LIMS), wraps up the 2021 LIMS Webcast Series on Wednesday, December 8th with Using a LIMS to Streamline Your Quality Management System (QMS) and Document Handling Procedures. For most laboratories, the Quality Management System (QMS) creates efficient processes, helps to meet regulatory and quality program requirements, and ensures customer satisfaction...
The use of only one SEC column brings a certain limitation due to its dedicated pore size and a limited column volume. By coupling two columns this hurdle can be overcome. Doubling the column length implies a doubled column volume which results in improved resolution of peaks. Additionally, if using two columns with different pore size, the applicable molecular weight range can be increased significantly....
UK medical research charity LifeArc announces its commitment to spend up to £1.3 billion by 2030 to help deliver new diagnostics, drugs, devices and digital solutions that transform the way diseases such as motor neurone disease are prevented, identified and treated. LifeArc plans to double its average annual spend, over the period to 2030. And the charity aims to leverage additional money, skills and resource from others to multiply the impact they can have for patients, together...
The Pistoia Alliance, a global, not-for-profit alliance that advocates for greater collaboration in life sciences R&D, has today outlined predictions for the life sciences industry in 2022. The predictions come from three experts recently appointed by the Alliance to drive collaboration efforts across its three key themes. Their insights span the urgent fights against antimicrobial resistance, the potential of quantum computing and commercial space travel, and autonomous laboratories.
A Schlenk Line is a tubular glass apparatus commonly used in chemistry or material laboratory research to carry out experiments under a vacuum and an inert atmosphere (like nitrogen or argon). It is used when samples are sensitive to air/moisture and the vacuum is also often used to remove the last traces of solvent from a sample. A Schlenk Line typically contains a dual glass manifold with multiple ports; the number of ports is configurable....
Porvair Sciences has published an in-depth application report demonstrating how their Microlute® CP Reverse Phase Solid Phase Extraction (SPE) microplates provide a robust and highly reproducible SPE LC-MS sample preparation methodology for a range of neutral, acidic, and basic analytes. As a sample preparation method - Solid Phase Extraction is widely acknowledged as a 'go to' tool for the clean-up of samples before analysis by hyphenated techniques such as LC/MS or GC/MS...
INTEGRA Biosciences – a leading provider of high quality laboratory equipment – supplies a comprehensive range of liquid handling tools that are ideal for sterile cell biology workflows. Each piece of equipment, from electronic pipettes to robotic pipetting systems and media dispensers, has been expertly designed to fit comfortably under a laminar flow hood to reduce the risk of cell culture contamination....
Merck, a leading science and technology company, has unveiled a representative study on scientific research productivity. Research productivity is defined in this study as the ratio of measurable input (e.g. number of researchers, financial investment) to measurable output (e.g. patents, publications). The study identified four factors that impact on research productivity in organizations worldwide...
Pharmaceutical solutions provider Pharmidex Pharmaceutical Services Ltd has massively increased its testing capacity with the help of a hire purchase solution from Siemens Financial Services (SFS). Founded in 2002, Pharmidex is a Contract Research Organisation (CRO) that provides high-quality bespoke experimental data to support drug discovery and development. Following its Medicines and Healthcare products Regulatory Agency (MHRA) accreditation, the company wanted to invest in the best possible technology to pursue its research...
CN Bio, a leading Organ-on-a-chip Company (OOC) that designs and manufactures single- and multi-organ microphysiological systems (MPS), has announced a research collaboration with the Infection Innovation Consortium (iiCON), a global collaborative infectious disease R&D programme, to validate the next generation of COVID-19 research tools. iiCON’s £174 million programme brings together industry, academia, and clinicians to accelerate the discovery, development...
A promising new approach to potentially treat Alzheimer’s disease – and also vaccinate against it – has been developed by a team of UK and German scientists. Both the antibody-based treatment and the protein-based vaccine developed by the team reduced Alzheimer’s symptoms in mouse models of the disease. The research is published in Molecular Psychiatry. The work is a collaboration between researchers at the University of Leicester, the University Medical Center Göttingen and the medical research charity LifeArc....
Eppendorf Lab Channel is a virtual platform where anyone can watch live and on-demand webinars for free, along with new product and application demonstrations. Peek over the shoulders of Eppendorf experts and let the details and insights illuminate the lab world. Attendees are encouraged to ask questions, interact with the experts, and gain new experiences up close and live....
Guardant Health, Inc. (Nasdaq: GH), a leading precision oncology company, and The Royal Marsden NHS Foundation Trust, one of the United Kingdom’s (UK) leading cancer research organizations, have agreed to enter into a partnership to establish an in-house liquid biopsy testing service using Guardant Health’s industry-leading proprietary digital sequencing platform....
INTEGRA’s VOYAGER adjustable tip spacing pipette is supporting crucial experimental work in longitudinal HIV studies. There have recently been tremendous breakthroughs in treatment of HIV infections, but challenges still remain. Scarlette Abbou, an engineer at the French National Centre for Scientific Research (CNRS), explained her lab’s work in this field: “CD4 T-cells – among others – act as reservoirs for HIV, and are established during the earliest stage of infection....
Hemp and marijuana are becoming more popular because of legalisation in multiple countries. The increase of this market also increases the offer of products and therefore the need to monitor different components. This application focusses on Residual Solvent analysis but Scion Instruments has an extended portfolio including potency analyses (AN091, 92, 93 and 130) and Terpene analysis (AN133 and 136) Residual Solvents are organic volatile products that are often used for the extraction...
Ziath reports how it has worked with the Hubrecht Institute (Utrecht, Netherlands) which has developed a pioneering automated test robot, called STRIP-1, which can process up to 20,000 samples for SARS-CoV-2 testing in just 24 hours. This makes it much faster than all other automated SARS-CoV-2 testing systems used to date. In addition, all samples can be tracked precisely because they have a 2D-barcode on the bottom of each tube that is scanned multiple times throughout the process....