Exeter Analytical, specialists in elemental microanalysis, has developed proprietary techniques based on their Model 440 CHN analyser to enable accurate determination of percentage Carbon (C) and Hydrogen (H) in Carbon fibre composite materials.

Carbon fibre analysis is of great interest to developers of products that benefit from the unique strength to weight ratio and rigidity of Carbon fibre reinforced materials - often referred to as carbon fibre composites. Applications for Carbon fibre composites include aerospace, marine craft, formula 1 and high-end automobiles, bicycles, sports equipment and firearms manufacture. With this wide range of applications comes the need for accurate Carbon fibre / composite materials analysis...

AMSBIO has introduced a new range of neural progenitor cells, and cerebral cortical neurons, derived from human induced pluripotent stem (iPS) cells.

Despite the large investment and interest in neuroscience traditional methods of studying the human nervous system and disease pathogenesis and mechanisms required the generation of animal models. However, these methods are time consuming, costly and often fail to replicate the desired human pathologies and symptoms. Using cutting-edge stem cell technologies to generate high purity human neural cells and neurons, AMSBIO is able to provide healthy and Alzheimer disease patient derived cerebral cortical neurons and neural progenitor cells...

New Insights Published on Key Protein Interactions Involved in the Bacterial Flagellar Motor Complex Show Promise for Other Difficult Biomolecular Systems

New Application Note from Wyatt Technology Showcases the Ability of CG-MALS to Quantify Complex Proteins. Wyatt Technology Corporation, the world leader in absolute macromolecular characterization instrumentation and software, has today published a new application note highlighting a study on the complex interactions between proteins and how they modulate the rotational direction of bacteria flagella....

Link Technologies provides key protocols for oligonucleotide synthesis and modification 

Link Technologies Ltd, an ISO 9001:2008 certified specialist oligonucleotide reagent manufacturer, is providing scientists with a complete resource for oligonucleotide synthesis and modification. Spanning the breadth of oligo chemistry, the Link Technologies 2013/14 Product Guide leads users through practical methods and application-based advice for total assurance in reagent selection and performance of the resulting oligos....

Drawing upon many years’ experience, AMSBIO has developed a custom phospho-specific antibody production service that is both reliable and produces highly specific quality antisera.

Phospho-specific antibodies are widely accepted for use in defining regulatory mechanisms that control cell functions such as activation of enzymes and receptors, cellular transcription, signal transduction, and cell signalling networks. Phospho-specific antibodies from AMSBIO are affinity-purified rabbit polyclonal or monoclonal antibodies that are monospecific for a target protein that is phosphorylated on a specific tyrosine, threonine, or serine residue...

Preclinical results have already demonstrated its remarkable action on solid tumors

A first proprietary product is under development to treat ovarian cancer. This platform can be used with a wide range of anti-tumoral agents. Adocia a biotechnology company specializing in the development of ‘best-in-class’ medicines from already approved therapeutic proteins, announces today the signature of an exclusive license agreement with the CNRS, the University Bordeaux I, the Institut Polytechnique de Bordeaux and Aquitaine Science Transfert (SATT Aquitaine)...

Evolving Applications for Sintered Porous Plastics

Porvair Filtration Group has written a technical article that documents the evolution of how sintered porous plastics have been used in industrial applications to their incorporation today in novel Chromatin Immunoprepitation (ChIP) assay kits used by scientists at the forefront of epigenetics research. Sintered porous plastics are produced by heat sintering together porous polymers such as polyethylene and polypropylene...

Thermo Fisher Scientific is pleased to announce a new technical note which demonstrates high resolution chromatographic separations of organic acids in beer samples.

Organic acids are end products of yeast fermentation critical to the flavor of beer, but are also products of bacterial fermentation that introduce a sour flavor, either purposely or unintentionally due to spoilage. Technical Note 126: Determination of Organic Acids in Beer Samples Using a High-Pressure Ion Chromatography System specifically discusses the separation of organic acids in beer samples using a Thermo Scientific™ Dionex™ IonPac™ AS11-HC-4μm anion-exchange column....

Harvard professor explains how to programme complex oligo structures for new applications 

The quarterly newsletter DECODED, from Integrated DNA Technologies (IDT) explores the work of Dr Pen Yin, assistant professor of systems biology at Harvard Medical School, who is harnessing the base pairing properties of DNA to create 3D structures of “DNA bricks”. This new nano-construction technique is based on short DNA oligos, which assemble at right-angles to interlocking sequences, forming 3D units. With such a heavy dependency on oligonucleotide quality, Dr Yin has relied on IDT. These DNA bricks are inspiring many future applications, such as catalysts and drug compounds, and can eventually be used to create electrical circuit boards on the nanometer scale...

Dates and Agenda Set, Registration Now Open for Quantitative Proteomics and ProteoMMX 3.0 Events

Waters Corporation (NYSE:WAT) and the Biochemical Society announced today the opening of registration for the Biochemical Society’s Quantitative Proteomics Training Day and the ProteoMMX 3.0 Symposium, consecutive events taking place March 24 - 27, 2014 in Chester, England. The Quantitative Proteomics Training Day is aimed at researchers seeking to gain familiarity with the field of quantitative proteomics. ProteoMMX 3.0, following immediately after the Training Day, is dedicated to current thinking and state of the art research in quantitative proteomics...

Neutrophils are a vital part of the body’s immune system.

Recognized as the most abundant type of white blood cell present in human blood, neutrophils function primarily as the body’s first line of defense against infection and inflammation. Within minutes of stimulation, neutrophils migrate from the blood to tissue where they accumulate at sites of infection. One of the most common lab tests ordered on a regular basis is the counting of neutrophils in the blood (absolute neutrophil count)...

Titian’s Mosaic sample management software selected for the European Lead Factory initiative

Leading sample management software provider, Titian Software, has announced that its Mosaic software is to play a central role in compound library screening for a major new European drug discovery initiative, the European Lead Factory (ELF).  Following a successful bid to the Innovative Medicines Initiative (IMI), over 8.7m euros has been invested by BioCity Scotland (BCS) to establish a compound management facility at Newhouse Scotland, and selected Titian’s Mosaic sample management software for streamlining compound operations...

Malvern Instruments has posted a new application note demonstrating the use of the company’s Viscotek SEC-MALS 20 multi angle light scattering (MALS) detector for size exclusion chromatography (SEC) in the analysis of monoclonal antibodies.

The application note, ‘Molecular weight measurements of an antibody using Viscotek SEC-MALS 20’, reports experimental data for the analysis of aggregates within monoclonal antibody formulations and can be freely downloaded. Monoclonal antibodies are being targeted for use in a growing range of therapeutic applications. Measuring the molecular weight of the protein, monomer, oligomers and aggregates within the sample and in formulations is an important part of assessing their safety and efficacy as drugs.....

To Rapidly Optimise Detergent Chemistries to meet any Decontamination Regulations

Scientific Digital Imaging’s [AIM-SDI] Synoptics Health Division, a manufacturer of innovative digital imaging systems for healthcare applications, today announced that the UK’s leading healthcare detergent manufacturer and supplier, Serchem, is utilising ProReveal, a test to detect proteins on surgical instruments, to accurately diagnose the efficacy and optimise the chemistry of its detergents for protein removal....

NanoSight reports on how Nanoparticle Tracking Analysis, NTA, is being used to study extracellular vesicles in the research laboratories of Dr Gregory Gores of the Mayo Clinic in Rochester, Minnesota.

The Gores Laboratory of the Mayo Clinic does basic research into liver disease. One of the main research areas of interest is lipotoxicity and its role in development of nonalcoholic steatohepatitis, a common feature of metabolic syndrome or obesity. The group has developed the hypothesis that lipotoxicity induces the release of extracellular vesicles (exosomes and microvesicles) from the liver cells. They speculate that these extracellular vesicles are involved in immune cell recruitment and activation, resulting in liver inflammation...

LGC, has supported two surveys published recently in Nature Methods that demonstrate that there remains a lack of transparency in the published literature

LGC, UK’s designated National Measurement Institute (NMI) for chemical and bioanalytical measurement, has supported two surveys – published recently in Nature Methods - that demonstrate that there remains a lack of transparency in the published literature when real time quantitative PCR (qPCR) data is presented. The surveys also reveal that literature citing MIQE (Minimum Information for Publication of Quantitative Real-Time PCR Experiments) show greater transparency and reporting of the technical details necessary for high-quality, reproducible results...

Move Will Prevent Millions of Animals From Having Harsh Chemicals Dripped Into Their Eyes and Rubbed Into Their Skin 

After an extensive PETA India campaign, with help from MP Maneka Gandhi and others – the Drugs Technical Advisory Board (DTAB), which operates under the Ministry of Health & Family Welfare, has recommended the addition of a suitable provision under The Drugs and Cosmetics Rules, 1945, to prohibit the import of cosmetics that have been tested on animals abroad. This decision – made in the DTAB's 65^th meeting, held on 25 November 2013 – comes on the heels of recently enacted bans on the import, marketing and sale of cosmetics and their ingredients tested on animals in the European Union and Israel as well as a recent decision to eliminate animal tests for cosmetics by the Bureau of Indian Standards, which oversees standards for cosmetics...

More testing and better treatment coverage recommended

According to new data issued today by the European Centre for Disease Prevention and Control (ECDC) and the WHO Regional Office for Europe, more than 131 000 new HIV infections were reported in the WHO European Region in 2012: 10 000 (8%) more than in 2011. This confirms a steady increase across the Region over that year: a 9% rise in countries in eastern Europe and central Asia (EECA) and a less than 1% rise in countries in the European Union and European Economic Area (EU/EEA)...

Thermo Fisher has developed a multianalyte-targeted technique that uses a spectro-electro array platform to resolve and quantify phenols, phenolic acids, and polyphenolsin a variety of natural products, supplements, herbs, spices, and beverages.

Application Note 1063: Targeted Analyses of Secondary Metabolites in Herbs, Spices, and Beverages Using a Novel Spectro-Electro Array Platformdemonstrates that this approach extends the range of compounds that can be simultaneously detected and enables the separation and quantitation of 49 different phytochemicals commonly found in a number of herbs, spices, and beverages...

Thermo Fisher Scientific has developed an ion chromatography (IC) method for determining low concentrations of morpholine in linezolid using an eluent generation system with suppressed conductivity detection.

Morpholine is used in the synthesis of linezolid and may be present in the drug product. This approach achieves efficient separation using a high-performance cation-exchange column with a high-purity electrolytically generated methanesulfonic acid eluent. Application Note 1062: Determination of Morpholine in Linezolid by Ion Chromatography demonstrates that this IC method also allows simultaneous determination of sodium, ammonium, potassium, and other cations present in the sample...

The DNA Section of the Orange County Crime Laboratory (OCCL) in California, USA, has recently taken delivery of its first Air LiHa equipped Freedom EVO^® workstation for DNA quantitation and amplification reaction set-up.

Complementing the laboratory’s existing liquid displacement Freedom EVO platforms for DNA extraction, this new instrument will help to streamline the workflow and improve pipetting precision. Robert Binz, a Forensic Scientist at OCCL, explained: “We purchased our first Freedom EVO in 2010 to speed up DNA extraction....

JPK Instrument reports on how the NanoWizard AFM is being applied in the study of nanostructures and nano-sized systems

JPK Instruments, a world-leading manufacturer of nanoanalytic instrumentation for research in life sciences and soft matter, reports on how the NanoWizard AFM is being applied in the study of nanostructures and nano-sized systems at the École Polytechnique Federale de Lausanne. The Laboratory of the Physics of Living Matter (LPMV) at the École Polytechnique Federale de Lausanne, better known as EPFL, uses various techniques for the study of the nanosciences....