Exeter Analytical has produced a new video that provides an informative introduction to the technique of elemental microanalysis that provides precise determination of percentage Carbon (C), Hydrogen (H) and Nitrogen in a sample.

The use of CHN microanalysis as a routine technique to provide a precise and accurate elemental analysis of a sample is widely accepted across many market sectors worldwide. CHN microanalysis is a powerful and relatively straightforward method for determining whether or not a sample is pure by providing a precise and accurate analysis of a sample's percentage carbon, hydrogen and nitrogen content....

Linkam Scientific Instruments report on the use of their stages for supramolecular polymer research at the Eindhoven University of Technology in the Netherlands.

As part of the Supramolecular polymer chemistry group at the Eindhoven University of Technology, Doctorial candidate Berry Bögels and his colleagues are focused on using self-assembly to create smart materials. –Specifically, Mr Bögels has been working on developing membranes that can be used in applications such as drug delivery systems, dialysis and biosensors.....

Ground-breaking speed and resolution of Andor iStar ICCD camera provides instantaneous visual evidence of quantum entanglement events for the first time.

Quantum Entanglement is one of the most counterintuitive features of quantum mechanics, in which the quantum states of two physically separated particles are linked. If a measurement is made that causes one particle of a pair to take on a definite value, the other particle will take the anti-correlated value instantaneously, even when separated by large distances.....

Quotient Clinical – the pioneer of Translational Pharmaceutics™ – has announced a significant expansion of its capacity and capabilities.

This investment is a direct response to the rapid rate of adoption of the Company’s Translational Pharmaceutics platform and unique approach by a growing international client base. Translational Pharmaceuticsintegrates formulation development, real-time manufacturing and clinical testing to offer shorter timelines, reduced costs and increased success rates in early phase drug development....

Children learning to speak depend on functional hearing.

So-called cochlear implants allow deaf people to hear again by stimulating the auditory nerve directly. Researchers at the Technische Universitaet Muenchen (TUM) are working to overcome current limits of the technology. They are investigating the implementation of signals in the auditory nerve and the subsequent neuronal processing in the brain. Using the computer models developed at the TUM manufacturers of cochlear implants improve their devices...

New Eppendorf Microinjection Suite at the Hadyn Ellis building supports researchers in pioneering work

As part of Eppendorf’s commitment to UK Science and to delivering the highest quality instruments and consumables to the life science community, the company has provided Cardiff University’s flagship Hadyn Ellis building, newly opened in November 2013, with a complete microinjection facility. The new Eppendorf Microinjection Suite will support pioneering work in critically important areas such as how recently identified ‘cancer stem cells’ drive the growth of the most common types of cancer, as well as bringing about a better understanding of a range of neurodegenerative disorders...

The primary particle in the perception of the visible range

Mankind has always enjoyed enduring works of art. The particles of the pigments have always been playing a major role. For example, the oldest cave paintings still impress us today. One of the most renowned experts for the production of historical pigments is Dr. Kremer from Aichstetten (Bavaria, Germany). FRITSCH laboratory mills are of great importance in Dr. Kremer’s pigment processing....

Graduates from the Centre’s four year PhD programme will lead new industries based on the optimal integration of photonics in electronic systems

UCL and Cambridge University have successfully gained funding for a new Engineering and Physical Sciences Research Council (EPSRC) Centre for Doctoral Training (CDT) in Integrated Photonic and Electronic Systems (IPES). The new Centre builds on the enormous success of the EPSRC funded collaboration between these two world-leading universities who set up a joint CDT for Photonic Systems Development in 2009...

Immune Response Triggered By Honeybee Venom Supports Hypothesis On The Origin Of Allergies 

Allergy-like immune reactions could represent a mechanism of the body that protects it against toxins. This surprising conclusion has been reached by scientists at Stanford University, USA, working on a research project co-financed by the Austrian Science Fund FWF. The recently published findings prove that honeybee venom triggers an immune response in mice associated with the formation of IgE antibodies, which are also typical for allergic responses....

Trio of Andor iXon EMCCD cameras on Revolution XD microscope make possible the simultaneous tracking of key autophagosome markers to deliver new insights into organelle biogenesis 

Frost & Sullivan: Healthcare innovation hinges on managing escalating amounts of data priming to more than triple the market

The partnership is based on Oncodesign's Nanocyclix(R) technology platform for next generation kinase inhibitors and UCB’s expertise in neurology  

Oncodesign, a drug discovery company and oncology pharmacology service provider, announces today that it has entered into a research collaboration and exclusive license option with UCB, a global biopharmaceutical leader specialised in neurology and immunology. The collaboration will leverage the respective expertise of Oncodesign and UCB to bring innovative therapeutic solutions to patients suffering from neurodegenerative disorders....

OGT provides insight on NGS enrichment optimisation

Oxford Gene Technology (OGT), provider of innovative genetics research and biomarker solutions to advance molecular medicine, has produced a free whitepaper titled ‘The importance of enrichment assay choice and optimisation for confident variant detection.’ The paper investigates the main strategies employed to optimise target enrichment for next generation sequencing (NGS) assays, assisting researchers to make informed decisions when designing studies...

A new application note from Malvern Instruments explores the role of particle size and the importance of particle size measurement in optimizing the formulation of drilling muds used in oil extraction processes.

TissueMark software automatically marks and detects potentially cancerous sections in tissue samples with unprecedented levels of speed and accuracy. 

Leap in precision equates to the shift from a freehand outline sketch of a country’s border to a high resolution map of the whole country. New technology, developed in Belfast, will soon enable pathologists to automate the process of marking tissue samples with unprecedented accuracy. TissueMark, developed by Belfast-based digital pathology specialists PathXL, is being launched today at the Association for Molecular Pathology conference in Phoenix, Arizona. TissueMark analyses the detailed structural patterns in tissue samples and marks the boundaries of potentially cancerous sections for more detailed analysis. The new software will help accelerate cancer research and discovery, reduce time in drug development and identify new markers of the disease...

Sanofi Pasteur Initiates Phase III Study of Investigational Clostridium Difficile Vaccine

Cdiffense trial to evaluate vaccine against a leading cause of life-threatening, healthcare-associated infections worldwide. Sanofi Pasteur, the vaccines division of Sanofi (EURONEXT: SAN and NYSE: SNY), announced today the initiation of its Phase III clinical program called Cdiffense to evaluate the safety, immunogenicity and efficacy of an investigational vaccine for the prevention of primary symptomatic Clostridium difficile infection (CDI). Clostridium difficile (C. diff) is a potentially life-threatening, spore-forming bacterium that causes intestinal disease....

Modeling Interactions Could Further Research of Treatments for Chronic Muscular Diseases

“Current drug development processes take anywhere from 10-15 years and cost somewhere in the region of $1.2 billion.” Neuromuscular junction studies are mainly concerned with understanding the connection between the nervous system and the muscular system, specifically with the synapses that transmits information across and back. By modelling this interaction in the lab, scientists hope to investigate subtle changes in muscle functional outputs in response to treatment with novel modulatory and inhibitory compounds. Such a system may prove invaluable in furthering research efforts aimed at the development of effective treatments and reducing the overall cost of clinical trials...

New customer feedback points up benefits of the Mastersizer 3000

A recent webinar showcasing new software features for the Mastersizer 3000 proved an opportunity for Malvern Instruments’ customers to reflect on how, two years on from its launch, this groundbreaking instrument is delivering valuable benefits. Customers cite its small footprint, truly intuitive and intelligent software interface, as well as the ease of transferring from an existing system to the new instrument, as the most popular features. The new software further enhances these elements of performance and was demonstrated during the webinar...

Bruker has released an application note on the evaluation of matrix effects on the analysis of carbendazim in orange juice and wine using the EVOQ Elite liquid chromatography mass spectrometer (LC-MS/MS).

Carbendazim is a fungicide and a known endocrine with potentially harmful effects on human health. The US Food and Drug Administration (FDA) has limited the concentration of carbendazim in imports to 10 ppb. Using the EVOQ, Bruker has developed a quantitative Multiple Reaction Monitoring (MRM) method for carbendazim analysis in orange juice and wine matrices. The EVOQ’s sensitivity was demonstrated as detections of 0.005 ppb were made, far below the FDA limit. The application note is available to download...

Autoscribe has published a new case study that shows how Thornton & Ross has improved its QC laboratory efficiency using the Matrix Gemini Laboratory Information Management System (LIMS).

Thornton & Ross Ltd is the largest independent pharmaceutical manufacturer in the UK. Its QC laboratory has an important function in both raw material evaluation and in production and this can significantly impact overall manufacturing performance. Thornton and Ross identified the need for a LIMS capable of controlling, managing, organising, documenting, analysing and reporting information, since increasing volumes of laboratory test data were overwhelming existing practices. Matrix Gemini was installed to manage data for a wide range of analytical techniques for both the raw materials and finished products teams...

Telstar has successfully developed two high containment barrier systems for the Korean Komipharm Pharmaceuticals Co Ltd, one of the largest producers of products from anti-cancer drugs in human oral dosage form to veterinary medicines in Asia

• Specially orientated to the manufacture of oncological pharmaceutical products and research in the Biotechnology field 

• Developed with in-house containment technology, the systems have been designed and manufactured by the Technology Centre for Barrier Isolation Systems of Telstar, located in UK....

OGT’s ASHG 2013 workshop highlights the need for comprehensive genomic analysis

Oxford Gene Technology (OGT), provider of innovative genetics research and biomarker solutions to advance molecular medicine, has made a recording of its recent American Society of Human Genetics (ASHG) workshop available to watch online. The oversubscribed workshop, titled “Complementing next generation sequencing experiments with high-resolution copy number variation detection”, was recorded at the meeting in Boston (US) on the 25^th of October 2013...