Malvern Instruments will introduce the Zetasizer µV with OmniFACE and OmniSEC, a new SEC-LS (size exclusion chromatography - light scattering) detector package, at SCM-5, the 5^th International Symposium on the Separation and Characterization of Natural and Synthetic Macromolecules (26-28 January, Amsterdam).  

The proven Zetasizer µV offers dual DLS (dynamic light scattering) and SLS (static light scattering) capabilities. It can be used as a stand-alone detector analyzing samples in a cuvette, and now as a fully-featured modular chromatography detector. For protein applications, this makes the Zetasizer µV an ideal tool. Applications in stand-alone batch mode include the study of molecular size and formulation stability, and in SEC detector mode the measurement of molecular weight, determination of oligomeric state and detection and quantification of oligomers and aggregates.   

Malvern specialists are also taking an active role in the SCM-5 conference, presenting a paper on ‘Exploring the relationship between intrinsic viscosity and protein structure'.  

Malvern offers a range of solutions for characterizing natural and synthetic macromolecules. These include the Zetasizer family, employing dynamic and static light scattering to measure size and molecular weight; Viscotek advanced gel permeation chromatography/size exclusion chromatography (GPC/SEC) systems and detectors for rapid, reliable characterization of  molecular weight and molecular structure; and the Sysmex FPIA-3000 for dynamic imaging including applications for characterizing sub-visible/visible particles and the size and shape of protein aggregates.  

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