Dionex is proud to announce a newly developed method that can fully recover low concentrations (< 1 μg/L) of three microcystins (-RR, -YR, and -LR) when added to water samples. Application Note 261: Sensitive Determination of Microcystins in Drinking and Environmental Waters demonstrates recovery at lower concentrations than the maximum recommended by the World Health Organization (WHO). This method is fully automated and easily configured on an UltiMate® 3000 ×2 Dual HPLC system, using Acclaim® PA2 columns for solid-phase extraction (SPE) and analysis.

Microcystin contamination of drinking water at low nanomolar concentrations is considered a risk factor for cancer; therefore, WHO has proposed a provisional guideline concentration of 1.0 μg/L for microcystin-LR in drinking water. This new target-cut on-line SPE method with dual function (analyte capture and partial separation) operates under automatic control of Chromeleon® Chromatography Data System (CDS) software and offers full automation, absence of operator influence, and strict process control.

Dionex (NASDAQ:DNEX) is a global leader in the manufacturing and marketing of liquid chromatography and sample preparation systems, consumables, and software for chemical analysis. The company's systems are used worldwide in environmental analysis and by the life sciences, chemical, petrochemical, food and beverage, power generation, and electronics industries. Our expertise in applications and instrumentation helps analytical scientists to evaluate and develop pharmaceuticals, establish environmental regulations, and produce better industrial products.

Acclaim, Chromeleon, and UltiMate are registered trademarks of Dionex Corporation