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BMG LABTECH and InvivoSciences, Inc. Initiate Market Collaboration to Accelerate Drug Discovery in Engineered 3D Tissues

BMG LABTECH and InvivoSciences announced today a strategic collaboration to market the time-dependent fluorescent assessment of engineered 3D heart tissues using advanced microplate reader technologies.

CLARIOstar The Microplate Reader from BMG LabtechBMG Labtech, Inc. - the Microplate Reader Company - and InvivoSciences, Inc. - a leader in stem cell tissue engineering providing a novel solution in first-in-class drug discovery - announced today a strategic collaboration to market the time-dependent fluorescent assessment of engineered 3D heart tissues using advanced microplate reader technologies.

Employing an automated system, 3D heart tissues are fabricated with cardiomyocytes derived from human induced pluripotent stem cells. The ultra- sensitive plate reader, CLARIOstar®, will analyze rapid beat-to-beat changes (up to 50 Hz) in the fluorescence intensities of dyes that indicate physiological states in engineered 3D heart tissue after drug/compound application.

In addition, InvivoSciences, Inc. is sponsoring a workshop during Cell Based Assays Summit in Munich Germany, December 02-04, 2013. BMG LABTECH will have a short presentation at the workshop to discuss applications of microplate readers in cell and tissue based assays.

While on January 20th 2014, InvivoSciences and BMG LABTECH will be presenting a workshop tutorial at Society for Laboratory Automation and Screening (SLAS) in San Diego, CA.

These Workshops will highlight applications of pluripotent cells and engineered tissues in drug discovery, including disease model generation as well as personalized and regenerative medicine. Cost-effective and flexible approaches of pluripotent cell culture and its scale up procedures will be presented.

"InvivoSciences has established themselves as a leader in engineered 3D tissues using pluripotent stem cells," said E.J. Dell, Ph.D., International Marketing Director of BMG LABTECH. "We are pleased to partner with them to create a drug discovery platform that is biologically more relevant to researchers."

Ayla Annac, Co-founder and CEO of InvivoSciences comments, "We are especially proud and pleased to establish a long-term relationship with the leading developer and internationally-recognized manufacture of microplate readers, BMG LABTECH."

BMG LABTECH is a leading developer and global manufacturer of microplate reader instrumentation. Produced in Germany since 1989, BMG LABTECH microplate readers represent the highest quality instrumentation of their kind. BMG LABTECH is dedicated to bringing the newest innovations in microplate reader technology to our customers in fields such as HTS, ADME/Tox, 3D cell-based analysis, and assay development.

InvivoSciences, Inc. (IVS) is discovering, developing, and commercializing 3D tissue-based high content analysis technology for drug discovery including drug repositioning, improving drug safety, and developing personalized medicine to improve human health.


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