Follow us...

 

Search News Archives

Channels

News

 

 

View Channel

Laboratory Products

 

 

View Channel

Special Offers and Promotions

 

Microscopy | Image Analysis

 

 

View Channel

Separation Science

 

 

View Channel

Coronavirus (COVID-19)

 

 

View Channel

Research & Case Studies

 

 

View Channel

Conferences | Events

Alfa Chemistry Offers Acylation Reagents for Gas Chromatography and Other Instrumental Analytical Methods  

publication date: Nov 11, 2022
 | 
author/source: Alfa Chemistry

20221101_1 

 

Earlier this month, Alfa Chemistry announced the launch of acylation reagents, a type of derivatization reagents frequently used in Gas Chromatography (GC) analysis, and other instrumental analytical scenarios.

In order to bring out the best chromatographic analysis effect, sample compounds need to meet a few criteria, for instance, high-temperature resistance and rapid transformation into the vapor state without degradation. However, if these criteria are not met, derivatization reagents generally undergo chemical modifications that rearrange or transform the original compounds, thus affording new compounds suitable for GC analysis. In most cases, derivatization serves as a procedural technique to escalate the volatility, selectivity, stability, and detectability of samples.

There are varieties of derivatization reagents, including alkylation reagents, silylation reagents, acylation reagents, fluorescent derivatization reagents, ultraviolet derivatization reagents, hydroxyl derivatization reagents, chiral derivatization reagents, amino derivatization reagents and the like. Among them, acylation reagents are of vital importance for derivatization procedures as many compounds of interest consist of the amine and/or hydroxy groups.

Acylation can enhance the GC analytical performance due to increased analyte volatility. Acylation can also reduce the polarity of a molecule, making it more retentive in the reversed-phase HPLC applications, said one of the senior scientists from Alfa Chemistry.

Acid anhydrides, acid halides, and reactive acyl derivatives are the three types of acylation reagents that are most commonly used in acylation reactions for chromatography, with unique characterizations and applications.

Currently, Alfa Chemistry provides the following acylation reagents that customers can reach out to for their varied research purposes.

2,2,6,6-Tetramethyl-3,5-heptanedione (CAS 1118-71-4), 1-(Trifluoroacetyl)imidazole (CAS 1546-79-8), 6,6,7,7,8,8,8-Heptafluoro-2,2-dimethyl-3,5-octanedione (CAS 17587-22-3), N-Heptafluorobutyrylimidazole (CAS 32477-35-3), Methyl trifluoromethanesulfonate (CAS 333-27-7), Heptafluorobutyric anhydride (CAS 336-59-4), Pentafluoropropionic anhydride (CAS 356-42-3), Ethyl trifluoromethanesulfonate (CAS 425-75-2), Butylboronic acid (CAS 4426-47-5), N-Methyl-bis(trifluoroacetamide) (CAS 685-27-8), N-Methyl-bis-heptafluorobutyramide (CAS 73980-71-9), (±)-α-Methoxy-α-trifluoromethylphenylacetic acid (CAS 81655-41-6), 4-Bromophenacyl trifluoromethanesulfonate (CAS 93128-04-2), etc.

Ideally, a successful derivatization procedure should afford compounds that are readily distinguishable from starting materials and make sure that over 95 percent of the sample is derivatized. The scientist further added.

 

View Product Information

 

 

About Alfa Chemistry

Aiming high, Alfa Chemistry has become an established brand for troubleshooting challenges and difficulties arising from the analytical testing industry. The company is dedicated to the supply of a comprehensive range of reliable, high-purity reagents and standards for both manufacturers and analytical testing laboratories worldwide.

 

Recent news from Alfa Chemistry

 


If you have not logged into the website then please enter your details below.



 

Subscribe to any of our newsletters for the latest on new laboratory products, industry news, case studies and much more!

Newsletters from Lab Bulletin

 

Request your free copies HERE

 

 

 

Popular this Month

Top 10 most popular articles this month

 

Today's Picks

 

 


 

Looking for a Supplier?

Search by company or by product

 


Company Name:

Product:


 

 

 

 

Please note Lab Bulletin does not sell, supply any of the products featured on this website. If you have an enquiry, please use the contact form below the article or company profile and we will send your request to the supplier so that they can contact you directly.

Lab Bulletin is published by newleaf marketing communications ltd.


 

Media Partners