• Smart Subtract® enhances chromatographic subtraction, making GC–MS and GC×GC–MS data comparisons faster and more intuitive.
• Reduces analysis time from days to minutes by automating the identification of key differences between complex chromatograms.
• Designed for seamless integration into existing workflows, ensuring precise, user-friendly results without the need for statistical expertise.

SepSolve Analytical Ltd (Peterborough, UK) has launched Smart Subtract®, a powerful new tool that transforms how chromatographic data is compared. Identifying differences between ‘good’ and ‘bad’ batches has long been a time-consuming and labour-intensive process, often taking days or even weeks to yield meaningful insights. Smart Subtract reduces this to minutes while delivering more accurate results.

Smart Subtract redefines the familiar subtraction workflow by integrating advanced statistical algorithms, enabling analysts to pinpoint key differences with greater speed and accuracy. This allows for the faster detection of contaminants, odours in recycled materials, and subtle variations in fragrance formulations, among many other applications. Designed for flexibility, it supports a wide range of file formats for both 1D and 2D GC–MS, making it easy to integrate with existing instruments and workflows.

With its intuitive interface, Smart Subtract delivers clear, actionable results without the need for analysts to learn complex statistical methods. It generates a subtracted chromatogram that retains spectral information, enabling the automated identification of key differences in minutes. Its ability to quickly visualise and communicate findings makes it particularly valuable for teams sharing results with non-chemists and stakeholders, helping to streamline decision-making and enhance efficiency.

Dr Laura McGregor, Product Marketing Manager at SepSolve Analytical, said:  "With Smart Subtract, we're removing the bottlenecks in chromatographic data processing, giving analysts a faster, more efficient way to compare samples with confidence."

Smart Subtract is available now.

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