As the COVID-19 pandemic continues, the worldwide search for an effective treatment is still ongoing. Remdesivir and GS-441524 are antiviral drugs that have been examined for the treatment of COVID-19 caused by SARS-CoV-2 (severe acute respiratory syndrome coronavirus 2). Remdesivir is a nucleotide analogue inhibitor that can inhibit the replication of animal and human coronaviruses...
A new eBook from Freeman Technology, a Micromeritics company and global leader in powder characterisation, explores the application of powder flow measurements for monitoring and optimising granulation processes. Granulation is a vital unit operation for many industries, notably the pharmaceutical sector, but endpoint detection and scale-up remain a challenge. ‘Powder Flow Testing for Granulation Processes’ focuses on the value of bulk powder characterisation...
Method of choice: The combination of size exclusion chromatography (SEC) and light scattering detection (LS) determines molecular weight, especially for higher molecular species such as aggregates or oligomers. As an additional plus sample size and topology can also be revealed. Special attention needs to be turned to the quality of SEC columns in order to provide signals unaffected by spikes. YMC’s SEC columns support LS-detection perfectly due to a high level of inertness...
BioChromato Inc. has published a report describing how their ionRocket sample preparation device, used in combination with Direct Analysis in Real Time Mass Spectrometry (DART-MS) and Kendrick Mass Defect (KMD) analysis, provides a valuable new tool for chain analysis of fluoroelastomers. Because of their excellent heat, chemical and abrasion resistance - fluoropolymers are widely used in automotive parts and many other industrial products....
This guide is for anyone working in a biobank or laboratory seeking a comprehensive and reliable way of identifying and tracking biological samples destined for long-term cryogenic storage in liquid nitrogen or ultra-low temperature freezers. The guide should impart the reader with a deeper understanding of the many attributes of a cryogenic label, the thought process behind choosing a label, the selection of labels in the LabTAG catalog, and how to integrate it all within your process....
Porvair Sciences Ultraseal Pro is the new fully automated heat-sealing instrument designed to consistently seal and protect a wide range of microplates and tubes. Protecting precious samples during storage and transportation is an essential final step for a wide range of laboratory and clinical applications. Of the various methods for sealing microplates, heat sealing has become the preferred option....
Have you ever experienced problems with a new method? Are your system suitability tests failing now for a method established years ago? Is is your HPLC column dying too fast? There are many possible reasons for these issues and their root cause can be hard to find. Our new (U)HPLC Troubleshooting Guide provides an easy breakdown of potential solutions for the most common issues in analytical liquid chromatography...
It is well known that flow properties of powders are governed by the intrinsic grain properties and forces acting on and between the grains. It is no surprise that the amount of API present in a blend impacts powder processability. To this end, GranuTools has developed, over the past years, a whole range of state-of-the-art equipments to allow characterizing the flow properties of powders and granular materials in many different geometries to match process conditions....
Are you dealing with demanding substances that tend to coordinate with metals? Are you looking for an inert solution for your peptide/protein, (oligo)nucleotide or sensitive small molecules? This is the solution for your problems! The bioinert YMC-Triart columns are fully biocompatible due to their PEEK lined stainless steel column bodies and the use of PEEK frits. You can achieve excellent peak shapes for sensitive compounds. Check out YMC's new flyer to discover more about biocompatible YMC-Triart metal-free columns....
Download this free infographic from Thermo Fisher Scientific to learn about SARS-CoV-2 infection and replication, disease progression and spread of COVID-19, and the importance and types of COVID-19 testing. There are different types of technologies used to test for SARS-CoV-2. The two tests that are most often used are PCR and antigen. PCR is 99% accurate and detects viral ....
Analytik Jena has published a new e-book for water and wastewater analysis. It demonstrates efficient methods and solutions for a wide range of selected routine and special applications. The e-book focuses on some central areas of water and wastewater analysis: In addition to the analysis of TOC/TNb and AOX, elemental analysis, and UV/Vis spectroscopy, the e-book also highlights molecular biological detection solutions....
Porvair Sciences announce the availability of a new guide that makes selection of the optimum Solid Phase Extraction (SPE) microplate for your application both quick and easy. SPE is a widely used method of sample preparation that concentrates and purifies analytes from a solution by means of absorption, followed by the elution of the analyte with a solvent appropriate for instrumental analysis, with techniques such as LC-MS...
Cherwell Laboratories, specialist supplier of products for environmental monitoring and process validation, has drawn on its extensive pharmaceutical and related industry knowledge to publish an eBook titled, “Growth Promotion Testing: A Guide to Good Practices” which is available to download from Cherwell’s website. The guide is intended for anyone involved in growth promotion testing of microbiological media, providing an overview of key considerations and best practice for this key quality control (QC) test...
The 2021 Gilson Product Guide is now available to download. This year, it’s packed with our liquid handling, extraction and purification instruments, enabling verifiable science and making lab life easier for researchers. With the current pandemic, this new guide also features solutions dedicated to COVID-19 research. We’ve consolidated our tools, technology, services, and resources to help scientists as they ramp up testing capabilities or study the virus...
Autoscribe Informatics, a leading global laboratory informatics provider, announced the release of a new white paper examining the role of a Laboratory Information Management System (LIMS) in supporting ISO17025 accreditation. The white paper explores the ways in which a Laboratory Information Management System (LIMS) can play a key role in achieving, maintaining, and benefiting from ISO17025 accreditation.
Okadaic acid is diarrhetic toxin (DSP) which can be found in shellfish. Due to its inhibitory effects towards specific protein phosphatases it is a promising compound for various potential medical uses. This application note shows the LC-MS/MS analysis of okadaic acid and its derivates with different YMC-Triart phases. All phases are suitable for the separation of these compounds with high resolution....
In some methods derived from the Pharmacopoeia the stipulation of a specific injection solvent can lead to issues with peak shape and a reduced sensitivity for some or all compounds analysed. With a custom injection program, you can overcome this hurdle and still be conform to Pharmacopoeia guidelines. Your gain will be a higher chance to achieve your system suitability criterions and a more reproducible and robust analysis...
Scientific Laboratory Supplies are delighted to announce the new SLS Product and Chemicals Catalogues are both OUT NOW! Packed full of equipment, consumables and chemicals for any busy laboratory, regardless of application, there is plenty of choice from your favourite brands – all in one place. You will find over 15,000 products – 20% of which are new for this edition in the new product catalogue....
Autoscribe Informatics, a leading global laboratory informatics provider, announced the release of a new white paper on the validation of Laboratory Information Management Systems (LIMS). The white paper discusses what LIMS validation is and the steps involved, the responsibilities of the customer and supplier, how GAMP5 affects LIMS validation, and the deliverables you can expect from a LIMS validation project....
In order to address separation requirements of different compounds, YMC offers two different HIC columns, BioPro HIC HT and BioPro HIC BF. They both have in common their non-porous polymethacrylate particle, while their properties and chromatographic behaviours are quite different. In this application note the retention behaviour of BioPro HIC HT and BioPro HIC BF columns is compared by separating two commercial monoclonal antibodies from each other.
(U)HPLC analysis of original composition of cannabis plant material is necessary for such purposes as phenotype determination and quality control of medical cannabis used for therapeutic treatment. For fast and secure results YMC developed robust (U)HPLC methods for RP and chiral LC. Also, challenging distinction between cannabigerol (CBG) andcannabidiol (CBD) are easily achieved....
Scientific Laboratory Supplies (SLS) are pleased to announce the launch of their new Sustainable Laboratory Solutions brochure, web subsite and their pledge to the ‘One Tree Planted’ charity. After months of research into what their customers are really looking for, from a supplier, regarding sustainability within the laboratory environment SLS have brought together some really useful information to help laboratory...
As the COVID-19 pandemic continues, the worldwide search for an effective treatment is still ongoing. Remdesivir and GS-441524 are antiviral drugs that have been examined for the treatment of COVID-19 caused by SARS-CoV-2 (severe acute respiratory syndrome coronavirus 2). Remdesivir is a nucleotide analogue inhibitor that can inhibit the replication of animal and human coronaviruses...
A new eBook from Freeman Technology, a Micromeritics company and global leader in powder characterisation, explores the application of powder flow measurements for monitoring and optimising granulation processes. Granulation is a vital unit operation for many industries, notably the pharmaceutical sector, but endpoint detection and scale-up remain a challenge. ‘Powder Flow Testing for Granulation Processes’ focuses on the value of bulk powder characterisation...
Method of choice: The combination of size exclusion chromatography (SEC) and light scattering detection (LS) determines molecular weight, especially for higher molecular species such as aggregates or oligomers. As an additional plus sample size and topology can also be revealed. Special attention needs to be turned to the quality of SEC columns in order to provide signals unaffected by spikes. YMC’s SEC columns support LS-detection perfectly due to a high level of inertness...
BioChromato Inc. has published a report describing how their ionRocket sample preparation device, used in combination with Direct Analysis in Real Time Mass Spectrometry (DART-MS) and Kendrick Mass Defect (KMD) analysis, provides a valuable new tool for chain analysis of fluoroelastomers. Because of their excellent heat, chemical and abrasion resistance - fluoropolymers are widely used in automotive parts and many other industrial products....
This guide is for anyone working in a biobank or laboratory seeking a comprehensive and reliable way of identifying and tracking biological samples destined for long-term cryogenic storage in liquid nitrogen or ultra-low temperature freezers. The guide should impart the reader with a deeper understanding of the many attributes of a cryogenic label, the thought process behind choosing a label, the selection of labels in the LabTAG catalog, and how to integrate it all within your process....
Porvair Sciences Ultraseal Pro is the new fully automated heat-sealing instrument designed to consistently seal and protect a wide range of microplates and tubes. Protecting precious samples during storage and transportation is an essential final step for a wide range of laboratory and clinical applications. Of the various methods for sealing microplates, heat sealing has become the preferred option....
Have you ever experienced problems with a new method? Are your system suitability tests failing now for a method established years ago? Is is your HPLC column dying too fast? There are many possible reasons for these issues and their root cause can be hard to find. Our new (U)HPLC Troubleshooting Guide provides an easy breakdown of potential solutions for the most common issues in analytical liquid chromatography...
It is well known that flow properties of powders are governed by the intrinsic grain properties and forces acting on and between the grains. It is no surprise that the amount of API present in a blend impacts powder processability. To this end, GranuTools has developed, over the past years, a whole range of state-of-the-art equipments to allow characterizing the flow properties of powders and granular materials in many different geometries to match process conditions....
Are you dealing with demanding substances that tend to coordinate with metals? Are you looking for an inert solution for your peptide/protein, (oligo)nucleotide or sensitive small molecules? This is the solution for your problems! The bioinert YMC-Triart columns are fully biocompatible due to their PEEK lined stainless steel column bodies and the use of PEEK frits. You can achieve excellent peak shapes for sensitive compounds. Check out YMC's new flyer to discover more about biocompatible YMC-Triart metal-free columns....
Download this free infographic from Thermo Fisher Scientific to learn about SARS-CoV-2 infection and replication, disease progression and spread of COVID-19, and the importance and types of COVID-19 testing. There are different types of technologies used to test for SARS-CoV-2. The two tests that are most often used are PCR and antigen. PCR is 99% accurate and detects viral ....
Analytik Jena has published a new e-book for water and wastewater analysis. It demonstrates efficient methods and solutions for a wide range of selected routine and special applications. The e-book focuses on some central areas of water and wastewater analysis: In addition to the analysis of TOC/TNb and AOX, elemental analysis, and UV/Vis spectroscopy, the e-book also highlights molecular biological detection solutions....
Porvair Sciences announce the availability of a new guide that makes selection of the optimum Solid Phase Extraction (SPE) microplate for your application both quick and easy. SPE is a widely used method of sample preparation that concentrates and purifies analytes from a solution by means of absorption, followed by the elution of the analyte with a solvent appropriate for instrumental analysis, with techniques such as LC-MS...
Cherwell Laboratories, specialist supplier of products for environmental monitoring and process validation, has drawn on its extensive pharmaceutical and related industry knowledge to publish an eBook titled, “Growth Promotion Testing: A Guide to Good Practices” which is available to download from Cherwell’s website. The guide is intended for anyone involved in growth promotion testing of microbiological media, providing an overview of key considerations and best practice for this key quality control (QC) test...
The 2021 Gilson Product Guide is now available to download. This year, it’s packed with our liquid handling, extraction and purification instruments, enabling verifiable science and making lab life easier for researchers. With the current pandemic, this new guide also features solutions dedicated to COVID-19 research. We’ve consolidated our tools, technology, services, and resources to help scientists as they ramp up testing capabilities or study the virus...
Autoscribe Informatics, a leading global laboratory informatics provider, announced the release of a new white paper examining the role of a Laboratory Information Management System (LIMS) in supporting ISO17025 accreditation. The white paper explores the ways in which a Laboratory Information Management System (LIMS) can play a key role in achieving, maintaining, and benefiting from ISO17025 accreditation.
Okadaic acid is diarrhetic toxin (DSP) which can be found in shellfish. Due to its inhibitory effects towards specific protein phosphatases it is a promising compound for various potential medical uses. This application note shows the LC-MS/MS analysis of okadaic acid and its derivates with different YMC-Triart phases. All phases are suitable for the separation of these compounds with high resolution....
In some methods derived from the Pharmacopoeia the stipulation of a specific injection solvent can lead to issues with peak shape and a reduced sensitivity for some or all compounds analysed. With a custom injection program, you can overcome this hurdle and still be conform to Pharmacopoeia guidelines. Your gain will be a higher chance to achieve your system suitability criterions and a more reproducible and robust analysis...
Scientific Laboratory Supplies are delighted to announce the new SLS Product and Chemicals Catalogues are both OUT NOW! Packed full of equipment, consumables and chemicals for any busy laboratory, regardless of application, there is plenty of choice from your favourite brands – all in one place. You will find over 15,000 products – 20% of which are new for this edition in the new product catalogue....
Autoscribe Informatics, a leading global laboratory informatics provider, announced the release of a new white paper on the validation of Laboratory Information Management Systems (LIMS). The white paper discusses what LIMS validation is and the steps involved, the responsibilities of the customer and supplier, how GAMP5 affects LIMS validation, and the deliverables you can expect from a LIMS validation project....
In order to address separation requirements of different compounds, YMC offers two different HIC columns, BioPro HIC HT and BioPro HIC BF. They both have in common their non-porous polymethacrylate particle, while their properties and chromatographic behaviours are quite different. In this application note the retention behaviour of BioPro HIC HT and BioPro HIC BF columns is compared by separating two commercial monoclonal antibodies from each other.
(U)HPLC analysis of original composition of cannabis plant material is necessary for such purposes as phenotype determination and quality control of medical cannabis used for therapeutic treatment. For fast and secure results YMC developed robust (U)HPLC methods for RP and chiral LC. Also, challenging distinction between cannabigerol (CBG) andcannabidiol (CBD) are easily achieved....
Scientific Laboratory Supplies (SLS) are pleased to announce the launch of their new Sustainable Laboratory Solutions brochure, web subsite and their pledge to the ‘One Tree Planted’ charity. After months of research into what their customers are really looking for, from a supplier, regarding sustainability within the laboratory environment SLS have brought together some really useful information to help laboratory...