SCiLS Lab is the software developed by SCiLS GmbH which allows the user-friendly statistical analysis of large MALDI imaging datasets
MALDI (Matrix-Assisted Laser Desorption Ionization) imaging is a mass spectrometric imaging technique that allows the untargeted measurement of proteins, peptides, lipids, drugs and metabolites directly from tissue. MALDI imaging has been successfully applied in various research fields. A particular area of application is the histopathology research concerned with the definition of molecular phenotypes in cancer, like expression patterns that are associated with progression of cancer, or the discovery of novel proteins associated with metastasis....
At Forum Labo & Biotech, Malvern Instruments will exhibit the latest materials and biophysical characterization technology and instrumentation, including Archimedes, the new Zetasizer Nano ZSP and an extended range of sample dispersion accessories for the Mastersizer 3000.
In addition to participating in the exposition, the company is also running a half-day user training course on particle size measurement by laser diffraction and size of nanoparticles by dynamic light scattering, which is free of charge to Forum Labo attendees....
New Product Portfolio Release Significantly Reduces Hands-on Time for Tissue-based Research
Definiens, the global leader of image and data analysis solutions for quantitative digital pathology, today announced at the 4th International Definiens Symposium on Harvard Medical School campus the launch of new software that improves productivity in tissue-based research and biomarker development. The new software extends the functionality of Definiens’ existing product portfolio and provides a significant quality control advantage, with up to a two-fold reduction in hands on time for researchers.
Detection efficiency of Andor iXon 885 low-light EMCCD camera captures fluorescent interference patterns built up by individual massive molecules at double slit grating
Described as the "most beautiful experiment in physics", Richard Feynman spoke of the double-slit experiment as 'the heart of quantum physics', emphasizing how the diffraction of individual particles at a grating is an unambiguous demonstration of wave-particle duality and contrary to classical physics. Matter-wave interference has been observed for almost 90 years, first for electrons, neutrons, atoms, and small molecules. The first single-electron/double-slit experiment to back-up Feynman's assertion that an individual electron itself can behave like a wave was reported by Tonomura's team in 1989....
Read MoreJPK reports on the applied research of Ioan Notingher at the University of Nottingham using AFM and the Tip Assisted Optics module to study individual nanotubes and fibrils.May 9, 2013
JPK Instruments, a world-leading manufacturer of nanoanalytic instrumentation for research in life sciences and soft matter, reports on the research studies of Dr Ioan Notingher, associate professor in the faculty of science at the University of Nottingham.
With a research interest in the development of new optical and spectroscopic methods for studying biomaterials, he is applying JPK's atomic force microscope (AFM) system, the NanoWizard®, and tip assisted optics module (TAO). The research programmes of the Nottingham Nanoscience group span a range of exciting and topical themes in state-of-the-art nanoscale science.
FLIR Systems new Application Story Book brings together a wealth of useful information for organisations using or considering using thermal imaging for a scientific or research and development application.
Available as a pdf download or a 44-page hard copy brochure - the Applications Story Book provides a useful introduction to thermal imaging, how thermal imaging cameras work and reasons why you might choose to use this technique. The following pages detail the large number of Science / R&D applications where thermal imaging has become a preferred technique because of the information it can provide, its ease-of-use and non-destructive / non-contact testing methodology....
Read MoreMethod development to estimate the purity of vesicle preparations using Nanoparticle Tracking Analysis at the Cardiff University School of MedicineMay 7, 2013
NanoSight reports on how Nanoparticle Tracking Analysis, NTA, is being used in the development of a method to estimate the purity of vesicle preparations by comparing the ratio of nano-vesicle counts to protein concentration. This work is reported by Dr Aled Clayton of the School of Medicine at Cardiff University in an original research article published in the Journal of Extracellular Vesicles.
The School of Medicine at Cardiff University is one of the largest medical schools in the United Kingdom, home to over 3000 students and staff. It is a major international center for teaching and research providing a vibrant community of medical endeavor. The School is based at the University Hospital of Wales in Cardiff, but is also embedded at other hospital sites in Cardiff including Velindre Cancer Centre...
Read MoreAgar provides improved standards for AFM with Geller NIST and NPL-traceable calibration samplesMay 7, 2013
Agar Scientific, a leading supplier of microscopy accessories and consumables, provides NIST and NPL traceable Certified Reference Materials from Geller Microanalytical Laboratory.
As a leading supplier of accessories for microscopy, Agar Scientific has long been known for the quality of its wide range of calibration standards for Electron Microscopy. For AFM users, the Geller reference standards MRS-3, 4 and 5 are a series of high quality standards that are NIST/NPL traceable. They allow the accurate calibration of scanning probe instruments such as STM and AFM...
Read MoreLeica Microsystems and Leica Biosystems strengthen market position in BrazilMay 3, 2013
Long-Standing Leica Distributors Aotec Have Been Acquired
Leica Microsystems and Leica Biosystems have cemented ties with their Brazilian Leica distributor: All shares of Aotec Instrumentos Cientificos Ltda of São Paulo, Brazil, have been acquired. Aotec is a provider of microscopy and histopathology solutions and has been a Leica distributor for more than 25 years. All Aotec associates will remain with Aotec. Furthermore, the company is actively hiring additional staff to enlarge the Brazilian teams. Leica Microsystems and Leica Biosystems thereby strengthen their market position...
Read MoreMolecular Devices to exhibit at LaboTec Suisse 2013May 3, 2013
Molecular Devices will be showcasing their SpectraMax® i3 multi-mode microplate reader and AquaMax® Washer during LaboTec Suisse
The SpectraMax® i3 Multi-Mode Detection Platform is available as a stand-alone reader with three broad detection modes: luminescence, absorbance, and fluorescence. Users are then given the option to upgrade to additional applications and detection modes which expands the system's detection capability making it highly versatile, and able to offer application options far exceeding those of standard readers...
Unique QC and training software to help standardise blood film review
Haematology specialists, HORIBA UK Ltd – Medical, has introduced a new innovative service, The Quality Slide Program (QSP). Launched in France in 2012 to meet ISO guidelines for laboratory accreditation in blood film review and already used by over 40 laboratories, this program is now available in the UK. QSP is a digital blood cell morphology QC and training program. With the software, 6 digital blood films are published for download each month
Xmark Media reports on the 2013 Photonex London Roadshow
With the attendance topping over 200 delegates, the day proved to be an outstanding success with well-attended parallel scientific sessions complemented with a benchtop equipment exhibition.The 2013 Photonex London Roadshow organised by Xmark Media attracted over 200 delegates to an intensive day of scientific presentations, industry-led tutorials and a comprehensive equipment exhibition establishing the model for future meetings to be held across the UK in years to come. Sponsored by the UCL-Cambridge Centre for Doctoral Training (CDT) and held in the impressive setting of the North Cloisters at University College, London....
Greiner Bio-One, a leading technology partner for the diagnostic and pharmaceutical industries, is unveiling the 96 well SensoPlate Plus
As a microscopy plate with a transparent borosilicate glass bottom and a black cycloolefin frame, SensoPlate Plus was developed especially for use in high-resolution microscopy and fluorescence correlation spectroscopy (FCS). Microscopic applications such as confocal microscopy and fluorescence correlation spectroscopy are sophisticated methods that can benefit from SensoPlate Plus. Consisting of a black cycloolefin frame, 96 well SensoPlate Plus features an ultra-clear borosilicate 175 ?m cover glass bottom affixed with a low autofluorescence adhesive...
Read MoreAnalytik Jena Acquires UVPApr 19, 2013
Analytik Jena AG, based in Jena, Germany has acquired all of the outstanding shares of Upland, California based UVP, LLC including its subsidiary, Ultra-Violet Products, Ltd., located in Cambridge UK.
UVP is a leading manufacturer of bioimaging systems for applications in proteomics, genomics, plant and animal sciences. The company also manufactures ultraviolet products, light sources, and laboratory equipment such as hybridization ovens, transilluminators, crosslinkers and PCR hoods....
BioTek continues providing unique solutions and technological advancements in microplate instrumentation by proudly announcing the first combination Hybrid multi-mode microplate reader and imaging system — the Cytation™3 Cell Imaging Multi-Mode Reader!
By combining multi-detection and automated digital microscopy in one instrument, cell biology researchers can now glean data-rich quantitative and qualitative information from their cells like never before. Modular architecture allows users to select only what they need now, and upgrade with additional modes as their needs evolve...
Protea Biosciences, a leading developer of innovative bioanalytical products and services, announced today the release of an extended mass spectrometry imaging (MSI) service offering from the Mass Spec Imaging Center (MSIC™).
This new service portfolio offers advanced MSI services using Protea’s proprietary LAESI DP-1000 Direct Ionization System as well as MALDI (Matrix-Assisted Laser Desorption/Ionization) mass spectrometry for a wide variety of sample types and applications. “This new portfolio of services offers researchers an opportunity to ‘detect’ where their molecules of interest reside in a biological matrix,” said Alessandro Baldi PhD, Protea’s Vice President and General Manager. “This spatial information offers critical insight for researchers working in the fields like metabolomics, biomarker discovery, drug discovery, and histopathology.”....
Phenom-World’s proX desktop SEM will deliver more detailed information in an even faster way. The leading supplier of desktop scanning electron microscopes extends its integrated Element Identification software package with a comprehensive Elemental Mapping and Line Scan option
All Phenom-World scanning electron microscopes are intuitive to use, compact, fast to create results and built to high quality standards. The most extended solution in the range is the Phenom proX. The advanced system identifies different elements in a specimen by using the integrated Element Identification software and specially designed EDS detector...
Anasys Instruments continues to expand the capabilities of their nanoscale materials characterization techniques with the Lorentz Contact Resonance (LCR) imaging mode. This is now available for their afm+® and nanoIR™ systems
The Lorentz Contact Resonance imaging mode further enhances the capabilities of the afm+ and nanoIR systems from Anasys. LCR allows rapid broadband nanomechanical measurements over a range of temperatures. LCR imaging differentiates between multiple components of a sample and allows precise location of the probe for subsequent chemical or thermal analysis with nanoscale resolution...
Read MoreNew Software for Research & Scientific Thermal ImagersApr 16, 2013
FLIR Systems has introduced a new and considerably enhanced version of its FLIR ResearchIR thermal measurement, recording, and analysis software
Designed for research and development and advanced scientific applications, the new software provides a comprehensive set of easy-to-use acquisition, diagnostics, and data sharing tools. In addition the new software includes customisable, savable workspaces that allow users to simply arrange how images, data, charts, and plots are displayed. ResearchIR connects directly to scientific FLIR thermal imaging cameras via USB, Firewire, Gigabit Ethernet, and Camera Link enabling fast viewing of thermal snapshots and movie files...
Read MoreZEISS SIGMA used to analyze Russian meteorite that fell in Chelyabinsk regionApr 15, 2013
Carl Zeiss Microscopy announces that it provided equipment used in the analysis of a meteorite that recently fell in the Chelyabinsk region of Russia
Russian News Agencies said on 18 February that scientists have confirmed the extra-terrestrial origin of dozens of tiny fragments found near Chebarkul Lake. The analysis was performed by the Research-Educational Centre “Nanomaterials and Nanotechnologies" in Urals Federal University. The Ural Federal University (UrFU) is a state-owned university and one of nine in Russia which have the ‘Federal’ status....
Majority of SelectScience members voted for ZEISS light sheet microscope system
At the American Association for Cancer Research (AACR) Annual Meeting 2013 in Washington, D.C., USA, SelectScience announced that ZEISS Lightsheet Z.1 has been awarded with the Best New Life Science Product of 2012 by members of SelectScience. The winning product is recognized as having significantly contributed towards laboratory efforts in 2012...
Read MoreSouth Africa's University of the Orange Free State use Linkam's THMS600 stage to study liquid crystalsApr 12, 2013
Market leaders in temperature controlled microscopy, Linkam Scientific Instruments report on the use of the popular THMS600 heating stage for liquid crystal research at the University of the Free State, Republic of South Africa
Researchers in the physical chemistry department of the University of the Orange Free State (UFS) have examined the discotic liquid crystal properties of a number of long chain metal free and zinc phthalocyanines using the Linkam THMS600 hot stage. Phthalocyanines are aromatic compounds, with a variable length carbon chain, produced when the phthalocyanine molecule reacts with metals to form brightly colored complexes. These metal and non-metal derivatives are used for many applications, with new uses being continuously developed. They are found in dyes, chemical sensors, catalysts, non-linear optical materials and have been used for photodynamic cancer treatments....
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MALDI (Matrix-Assisted Laser Desorption Ionization) imaging is a mass spectrometric imaging technique that allows the untargeted measurement of proteins, peptides, lipids, drugs and metabolites directly from tissue. MALDI imaging has been successfully applied in various research fields. A particular area of application is the histopathology research concerned with the definition of molecular phenotypes in cancer, like expression patterns that are associated with progression of cancer, or the discovery of novel proteins associated with metastasis....
Definiens, the global leader of image and data analysis solutions for quantitative digital pathology, today announced at the 4th International Definiens Symposium on Harvard Medical School campus the launch of new software that improves productivity in tissue-based research and biomarker development. The new software extends the functionality of Definiens’ existing product portfolio and provides a significant quality control advantage, with up to a two-fold reduction in hands on time for researchers.
Described as the "most beautiful experiment in physics", Richard Feynman spoke of the double-slit experiment as 'the heart of quantum physics', emphasizing how the diffraction of individual particles at a grating is an unambiguous demonstration of wave-particle duality and contrary to classical physics. Matter-wave interference has been observed for almost 90 years, first for electrons, neutrons, atoms, and small molecules. The first single-electron/double-slit experiment to back-up Feynman's assertion that an individual electron itself can behave like a wave was reported by Tonomura's team in 1989....
With a research interest in the development of new optical and spectroscopic methods for studying biomaterials, he is applying JPK's atomic force microscope (AFM) system, the NanoWizard®, and tip assisted optics module (TAO). The research programmes of the Nottingham Nanoscience group span a range of exciting and topical themes in state-of-the-art nanoscale science.
Available as a pdf download or a 44-page hard copy brochure - the Applications Story Book provides a useful introduction to thermal imaging, how thermal imaging cameras work and reasons why you might choose to use this technique. The following pages detail the large number of Science / R&D applications where thermal imaging has become a preferred technique because of the information it can provide, its ease-of-use and non-destructive / non-contact testing methodology....
The School of Medicine at Cardiff University is one of the largest medical schools in the United Kingdom, home to over 3000 students and staff. It is a major international center for teaching and research providing a vibrant community of medical endeavor. The School is based at the University Hospital of Wales in Cardiff, but is also embedded at other hospital sites in Cardiff including Velindre Cancer Centre...
As a leading supplier of accessories for microscopy, Agar Scientific has long been known for the quality of its wide range of calibration standards for Electron Microscopy. For AFM users, the Geller reference standards MRS-3, 4 and 5 are a series of high quality standards that are NIST/NPL traceable. They allow the accurate calibration of scanning probe instruments such as STM and AFM...
Leica Microsystems and Leica Biosystems have cemented ties with their Brazilian Leica distributor: All shares of Aotec Instrumentos Cientificos Ltda of São Paulo, Brazil, have been acquired. Aotec is a provider of microscopy and histopathology solutions and has been a Leica distributor for more than 25 years. All Aotec associates will remain with Aotec. Furthermore, the company is actively hiring additional staff to enlarge the Brazilian teams. Leica Microsystems and Leica Biosystems thereby strengthen their market position...
The SpectraMax® i3 Multi-Mode Detection Platform is available as a stand-alone reader with three broad detection modes: luminescence, absorbance, and fluorescence. Users are then given the option to upgrade to additional applications and detection modes which expands the system's detection capability making it highly versatile, and able to offer application options far exceeding those of standard readers...
Haematology specialists, HORIBA UK Ltd – Medical, has introduced a new innovative service, The Quality Slide Program (QSP). Launched in France in 2012 to meet ISO guidelines for laboratory accreditation in blood film review and already used by over 40 laboratories, this program is now available in the UK. QSP is a digital blood cell morphology QC and training program. With the software, 6 digital blood films are published for download each month
With the attendance topping over 200 delegates, the day proved to be an outstanding success with well-attended parallel scientific sessions complemented with a benchtop equipment exhibition.The 2013 Photonex London Roadshow organised by Xmark Media attracted over 200 delegates to an intensive day of scientific presentations, industry-led tutorials and a comprehensive equipment exhibition establishing the model for future meetings to be held across the UK in years to come. Sponsored by the UCL-Cambridge Centre for Doctoral Training (CDT) and held in the impressive setting of the North Cloisters at University College, London....
As a microscopy plate with a transparent borosilicate glass bottom and a black cycloolefin frame, SensoPlate Plus was developed especially for use in high-resolution microscopy and fluorescence correlation spectroscopy (FCS). Microscopic applications such as confocal microscopy and fluorescence correlation spectroscopy are sophisticated methods that can benefit from SensoPlate Plus. Consisting of a black cycloolefin frame, 96 well SensoPlate Plus features an ultra-clear borosilicate 175 ?m cover glass bottom affixed with a low autofluorescence adhesive...
UVP is a leading manufacturer of bioimaging systems for applications in proteomics, genomics, plant and animal sciences. The company also manufactures ultraviolet products, light sources, and laboratory equipment such as hybridization ovens, transilluminators, crosslinkers and PCR hoods....
By combining multi-detection and automated digital microscopy in one instrument, cell biology researchers can now glean data-rich quantitative and qualitative information from their cells like never before. Modular architecture allows users to select only what they need now, and upgrade with additional modes as their needs evolve...
This new service portfolio offers advanced MSI services using Protea’s proprietary LAESI DP-1000 Direct Ionization System as well as MALDI (Matrix-Assisted Laser Desorption/Ionization) mass spectrometry for a wide variety of sample types and applications. “This new portfolio of services offers researchers an opportunity to ‘detect’ where their molecules of interest reside in a biological matrix,” said Alessandro Baldi PhD, Protea’s Vice President and General Manager. “This spatial information offers critical insight for researchers working in the fields like metabolomics, biomarker discovery, drug discovery, and histopathology.”....
All Phenom-World scanning electron microscopes are intuitive to use, compact, fast to create results and built to high quality standards. The most extended solution in the range is the Phenom proX. The advanced system identifies different elements in a specimen by using the integrated Element Identification software and specially designed EDS detector...
The Lorentz Contact Resonance imaging mode further enhances the capabilities of the afm+ and nanoIR systems from Anasys. LCR allows rapid broadband nanomechanical measurements over a range of temperatures. LCR imaging differentiates between multiple components of a sample and allows precise location of the probe for subsequent chemical or thermal analysis with nanoscale resolution...
Designed for research and development and advanced scientific applications, the new software provides a comprehensive set of easy-to-use acquisition, diagnostics, and data sharing tools. In addition the new software includes customisable, savable workspaces that allow users to simply arrange how images, data, charts, and plots are displayed. ResearchIR connects directly to scientific FLIR thermal imaging cameras via USB, Firewire, Gigabit Ethernet, and Camera Link enabling fast viewing of thermal snapshots and movie files...
At the American Association for Cancer Research (AACR) Annual Meeting 2013 in Washington, D.C., USA, SelectScience announced that ZEISS Lightsheet Z.1 has been awarded with the Best New Life Science Product of 2012 by members of SelectScience. The winning product is recognized as having significantly contributed towards laboratory efforts in 2012...
Researchers in the physical chemistry department of the University of the Orange Free State (UFS) have examined the discotic liquid crystal properties of a number of long chain metal free and zinc phthalocyanines using the Linkam THMS600 hot stage. Phthalocyanines are aromatic compounds, with a variable length carbon chain, produced when the phthalocyanine molecule reacts with metals to form brightly colored complexes. These metal and non-metal derivatives are used for many applications, with new uses being continuously developed. They are found in dyes, chemical sensors, catalysts, non-linear optical materials and have been used for photodynamic cancer treatments....