Thermo Fisher Scientific’s Cryo-TEM provides critical information for small molecule and biologic drug discovery
A new contract research laboratory operated by France-based NovAliX will provide pharmaceutical companies with access to high-resolution cryo-transmission electron microscopy (cryo-TEM) by Thermo Fisher Scientific for facilitating small molecule and biologic drug discovery. NovAliX’s new laboratory will use the cryo-TEM to provide two-dimensional...
AMSBIO has published a new 36-page catalogue that details its comprehensive range of high purity reagents for proteoglycan and glycosaminoglycan research.
Proteoglycans are glycosylated proteins which contain covalently attached highly anionic glycosaminoglycans (GAGs). Proteoglycans are present in different forms within different types of extracellular matrices and connective tissues. Heparan sulfate proteoglycans (HSPGs) are known to play important structural and functional roles in linking the component proteins of the basement membrane, controlling the permeability properties of the membranes and signal...
SCION Instruments, the world-renowned designer and manufacturer of GC, GC-MS systems and accessories has announced a number of improvements and upgrades to its portfolio of offerings at this year’s PITTCON.
Firstly, the company announces the release of its CompassCDS software platform v4.0, which features new capabilities that extend its applicability to a wider range of laboratories. CompassCDS brings more than 20 years of customer experience and development, and provides a user-friendly and application-rich GUI with unique integration and extended calculation and reporting capabilities.
The Micronic externally threaded 3.00ml tube provides an ideal and fully traceable storage solution for fresh frozen tissue samples with a size of 0.5cm3 to 1.0cm3.
Micronic 3.00ml tissue tubes offer easy and unambiguous identification and storage of fresh frozen tissue samples. The tubes have a unique 2D Data-Matrix code laser encrypted on the tube bottom and a large human readable code on the tube sidewall. The unique 2D code identifies the sample. Scanning the Micronic 24-2 storage rack will also identify the tube sample code with the location in the rack. For highly accurate and reliable results, the Micronic 3.00ml...
AMSBIO has introduced a new range of cancer cell line models and culture media for the most difficult to culture tumor types where no models may exist.
Alex Sim, Managing Director at AMSBIO said, "Our new partnership with Cellaria Biosciences expands our existing portfolio by introducing patient-derived cancer models; allowing customers to conduct research and drug discovery initiatives to advance precision medicine.” Directly derived from patient tumors without any genetic manipulation, these new products provide the assurance of primary cells....
Asynt has announced new inserts for its DrySyn heating blocks enabling scientists to now conduct precise temperature controlled, stirred experiments in 0.5-2ml tapered, 2-5ml and 10-20ml microwave vials.
Available as an option for the DrySyn Parallel Synthesis Kit the new microwave vial inserts allow you to heat and stir up to 27 small scale reactions in parallel using any standard hotplate. The DrySyn Parallel Synthesis kit enables clean, safe synthesis without the hazards or problems associated with silicon oil baths or heating mantles....
Metrohm USA is proud to announce the release of the Mira M-3 handheld Raman spectrometer.
Based on method-driven software, the M-3 changes the landscape of handheld Raman, bringing the controls of a benchtop instrument to a handheld platform. The M-3 allows full adjustment of laser power, integration time, and data processing through customizable operating procedures. Unlike competitive handheld instruments that hide all control of data collection, the user is able to...
Veolia Water Technologies is proud to announce the new arrival as part of its market-leading MEDICA EDI range of water purifiers.
Filling the long-standing gap in the market for the growing laboratories which require less than 50 litres of purified water per hour, the MEDICA EDI 15/30 is a compact, high performance water purification system designed to feed up to 1.5 l/min of CLRW standard grade water - directly to smaller Clinical Diagnostic Analysers....
Makes Identifying Microorganisms on HardyCHROM™ Media Quick and Simple
Synbiosis, a long-established, expert manufacturer of automated microbiological systems, today announced its Chromogenic ID software for use with ChromaZona, ProtoCOL 3 and Protos 3 automated colony counters has been upgraded and validated for automatic identification of bacteria and yeast on Hardy Diagnostics' HardyCHROM™ media....
The Lumen 200 Fluorescence Illumination System from Prior Scientific offers a powerful, cost effective alternative to traditional short arc Mercury vapour lamps and bulbs used in fluorescence microscopy.
Mercury vapour lamps and bulbs suffer from a number of limiting disadvantages including an operational lifetime rarely exceeding 200 hours and the need for time consuming alignment procedures during installation. In addition Mercury vapour bulbs are susceptible to flickering, limiting the use of these light sources in quantitative fluorescent microscopy....
Genevac has published an informative customer article that reviews the development of a new sample preparation method using its EZ-2 centrifugal evaporator to help simplify and accelerate the detection and quantitation of algal toxins in surface water.
Due to a warming global environment there has been a rise in occurrences of cyanobacteria blooms in lakes which can generate cyanotoxins. With surface water a major source of drinking water, the presence of cyano bacterial blooms pose a potential threat to human health. Using Ultra-high Performance Liquid Chromatography (UPLC) researchers have been able to...
The fluorescent probe NR12S detects changes in plasma membrane cholesterol levels
The cell membrane is a bilayer of phospholipids with embedded proteins. It contains cholesterol that determines the membrane’s fluidity, permeability and activity of membrane proteins. Changes in membrane cholesterol are implicated in diseases such as Alzheimer’s and cancer, demanding its investigation....
Horizon Discovery Group plc, the world leader in the application of gene editing technologies including molecular reference standards, announces the launch of its first HDx™ cfDNA (cell-free DNA) Reference Standard in Synthetic Plasma.
Since being pioneered by Horizon co-founder Professor Alberto Bardelli for the detection of KRAS mutations in serum to identify resistant populations to EGFR targeted therapy, liquid biopsy testing has emerged as one of the fastest growing areas in diagnostics, with cfDNA testing set to reach $9.0 billion by 2022....
Deben have supplied leading German instrument manufacturers, JPK Instruments, with a tensile stage to use in conjunction with the world-renowned NanoWizard® AFM platform.
Dr Torsten Mueller is a member of the development team with German nanoscience instrument makers, JPK Instruments. Dr Mueller and his colleagues are based in Berlin supporting a worldwide user network which is continuously testing JPK with requests for new capabilities for their life science and materials nanoscience systems....
New kit enables covalent conjugation of antibodies and proteins to magnetic particles
Innova Biosciences (Innova), a specialist provider of bioconjugation products and services, today announced the launch of its Magnetic Conjugation Kit, the newest addition to the company’s range of particle conjugation technologies. The new kit allows researchers to covalently conjugate antibodies and proteins to 0.5µm magnetic particles without the need....
The new MicroCal PEAQ-DSC microcalorimeter from Malvern Instruments resets the performance standard for characterizing protein and biomolecule stability.
This latest innovation in Differential Scanning Calorimetry (DSC) has been created specifically for the regulated environment and delivers essential data to guide biopharmaceutical development, from protein engineering, through pre-formulation and process development, to formulation and manufacture of the final product. The new system offers developers a quick stability assay to identify biotherapeutics with good stability potential and enables them to determine...
JPK Instruments reports on how STM is being used to study surface plasmons in the Molecular Nanoscience Group at ISMO – Institut des Sciences Moléculaires d’Orsay – CNRS and the Université Paris-Sud.
One of the research goals of the Molecular Nanoscience Group at ISMO is to work towards circuits and devices in which surface plasmons (not electrons or photons) are used to transfer and manipulate information. However, why develop plasmonics when there are already solutions using electronics and photonics?....
Breakthrough advance offers the potential to defuse a ‘ticking timebomb’ for serious lung disease, including for over 1 billion smokers worldwide
The world’s biggest study into an individual’s genetic make-up and the risk of developing lung disease could allow scientists to more accurately ‘predict’ - based on genes and smoking - your chance of developing COPD, a deadly disease which is the third commonest cause of death in the world....
Second Crowdcube campaign for growth and international expansion
Following on from an extremely successful fund raising campaign in 2015, and a product launch in July 2016, ioLight is delighted to announce that its second crowd funding campaign is now live on the Crowdcube platform. The ioLight microscope is the first professional quality pocket digital microscope....
AMSBIO has published a new 25-page Neuroscience catalogue that details its extensive range of specific tools and reagents to enable researchers stay at the forefront of their field.
Cellular models are key tools that open the door to numerous neuroscience applications including neurodegeneration, neurogensis and developmental diseases. With the discovery that neural stem cells exist in the adult brain many researchers are now seeking to use these cells in in vitro studies....
Biological experiments are generating increasingly large and complex sets of data.
This has made it difficult to reproduce experiments at other research laboratories in order to confirm – or refute – the results. The difficulty lies not only in the complexity of the data, but also in the elaborate computer programmes and systems needed to analyse them. Scientists from the Luxembourg Centre for Systems Biomedicine (LCSB) of the University of...
MRC researchers at the University of Leicester have shed light on critical gene network involved in neurological disease
“Studying the roles of genes such as ATF4 in human neurons could lead to tailored interventions that could one day prevent or delay the neuronal loss seen in Parkinson’s” – Dr Miguel Martins, MRC Toxicology Unit, University of Leicester. A genetic ‘switch’ has been discovered by MRC researchers at the University of Leicester which could help to prevent or delay the...
A new contract research laboratory operated by France-based NovAliX will provide pharmaceutical companies with access to high-resolution cryo-transmission electron microscopy (cryo-TEM) by Thermo Fisher Scientific for facilitating small molecule and biologic drug discovery. NovAliX’s new laboratory will use the cryo-TEM to provide two-dimensional...
Proteoglycans are glycosylated proteins which contain covalently attached highly anionic glycosaminoglycans (GAGs). Proteoglycans are present in different forms within different types of extracellular matrices and connective tissues. Heparan sulfate proteoglycans (HSPGs) are known to play important structural and functional roles in linking the component proteins of the basement membrane, controlling the permeability properties of the membranes and signal...
Firstly, the company announces the release of its CompassCDS software platform v4.0, which features new capabilities that extend its applicability to a wider range of laboratories. CompassCDS brings more than 20 years of customer experience and development, and provides a user-friendly and application-rich GUI with unique integration and extended calculation and reporting capabilities.
Micronic 3.00ml tissue tubes offer easy and unambiguous identification and storage of fresh frozen tissue samples. The tubes have a unique 2D Data-Matrix code laser encrypted on the tube bottom and a large human readable code on the tube sidewall. The unique 2D code identifies the sample. Scanning the Micronic 24-2 storage rack will also identify the tube sample code with the location in the rack. For highly accurate and reliable results, the Micronic 3.00ml...
Alex Sim, Managing Director at AMSBIO said, "Our new partnership with Cellaria Biosciences expands our existing portfolio by introducing patient-derived cancer models; allowing customers to conduct research and drug discovery initiatives to advance precision medicine.” Directly derived from patient tumors without any genetic manipulation, these new products provide the assurance of primary cells....
Available as an option for the DrySyn Parallel Synthesis Kit the new microwave vial inserts allow you to heat and stir up to 27 small scale reactions in parallel using any standard hotplate. The DrySyn Parallel Synthesis kit enables clean, safe synthesis without the hazards or problems associated with silicon oil baths or heating mantles....
Based on method-driven software, the M-3 changes the landscape of handheld Raman, bringing the controls of a benchtop instrument to a handheld platform. The M-3 allows full adjustment of laser power, integration time, and data processing through customizable operating procedures. Unlike competitive handheld instruments that hide all control of data collection, the user is able to...
Filling the long-standing gap in the market for the growing laboratories which require less than 50 litres of purified water per hour, the MEDICA EDI 15/30 is a compact, high performance water purification system designed to feed up to 1.5 l/min of CLRW standard grade water - directly to smaller Clinical Diagnostic Analysers....
Synbiosis, a long-established, expert manufacturer of automated microbiological systems, today announced its Chromogenic ID software for use with ChromaZona, ProtoCOL 3 and Protos 3 automated colony counters has been upgraded and validated for automatic identification of bacteria and yeast on Hardy Diagnostics' HardyCHROM™ media....
Mercury vapour lamps and bulbs suffer from a number of limiting disadvantages including an operational lifetime rarely exceeding 200 hours and the need for time consuming alignment procedures during installation. In addition Mercury vapour bulbs are susceptible to flickering, limiting the use of these light sources in quantitative fluorescent microscopy....
Due to a warming global environment there has been a rise in occurrences of cyanobacteria blooms in lakes which can generate cyanotoxins. With surface water a major source of drinking water, the presence of cyano bacterial blooms pose a potential threat to human health. Using Ultra-high Performance Liquid Chromatography (UPLC) researchers have been able to...
The cell membrane is a bilayer of phospholipids with embedded proteins. It contains cholesterol that determines the membrane’s fluidity, permeability and activity of membrane proteins. Changes in membrane cholesterol are implicated in diseases such as Alzheimer’s and cancer, demanding its investigation....
Since being pioneered by Horizon co-founder Professor Alberto Bardelli for the detection of KRAS mutations in serum to identify resistant populations to EGFR targeted therapy, liquid biopsy testing has emerged as one of the fastest growing areas in diagnostics, with cfDNA testing set to reach $9.0 billion by 2022....
Dr Torsten Mueller is a member of the development team with German nanoscience instrument makers, JPK Instruments. Dr Mueller and his colleagues are based in Berlin supporting a worldwide user network which is continuously testing JPK with requests for new capabilities for their life science and materials nanoscience systems....
Innova Biosciences (Innova), a specialist provider of bioconjugation products and services, today announced the launch of its Magnetic Conjugation Kit, the newest addition to the company’s range of particle conjugation technologies. The new kit allows researchers to covalently conjugate antibodies and proteins to 0.5µm magnetic particles without the need....
This latest innovation in Differential Scanning Calorimetry (DSC) has been created specifically for the regulated environment and delivers essential data to guide biopharmaceutical development, from protein engineering, through pre-formulation and process development, to formulation and manufacture of the final product. The new system offers developers a quick stability assay to identify biotherapeutics with good stability potential and enables them to determine...
One of the research goals of the Molecular Nanoscience Group at ISMO is to work towards circuits and devices in which surface plasmons (not electrons or photons) are used to transfer and manipulate information. However, why develop plasmonics when there are already solutions using electronics and photonics?....
The world’s biggest study into an individual’s genetic make-up and the risk of developing lung disease could allow scientists to more accurately ‘predict’ - based on genes and smoking - your chance of developing COPD, a deadly disease which is the third commonest cause of death in the world....
Following on from an extremely successful fund raising campaign in 2015, and a product launch in July 2016, ioLight is delighted to announce that its second crowd funding campaign is now live on the Crowdcube platform. The ioLight microscope is the first professional quality pocket digital microscope....
Cellular models are key tools that open the door to numerous neuroscience applications including neurodegeneration, neurogensis and developmental diseases. With the discovery that neural stem cells exist in the adult brain many researchers are now seeking to use these cells in in vitro studies....
This has made it difficult to reproduce experiments at other research laboratories in order to confirm – or refute – the results. The difficulty lies not only in the complexity of the data, but also in the elaborate computer programmes and systems needed to analyse them. Scientists from the Luxembourg Centre for Systems Biomedicine (LCSB) of the University of...