Metabolic phenotyping using nuclear magnetic resonance (NMR) spectroscopy and liquid chromatography-mass spectrometry (LC-MS) has been applied to the characterization of the metabolic effects of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection on human blood plasma. Metabolomic analysis was used to quantify key lipid and protein components of blood samples collected from...
INTEGRA Biosciences’ cost-effective liquid handling products are ideal for molecular diagnostics workflows, particularly during the COVID-19 crisis, making it easy for labs to scale up their testing capacities quickly and easily. It is often assumed that high throughput can only be achieved with huge investment. This simply isn’t the case with INTEGRA’s affordable pipetting solutions, which can increase lab productivity and the reproducibility of results, without the need for large liquid handling platforms and at an affordable price.
The Native Antigen Company (now part of LGC’s Clinical Diagnostics Division), one of the world’s leading suppliers of reagents that enables research into vaccines and diagnostics for emerging and endemic infectious diseases, has announced the introduction of ten new monoclonal antibodies recognising SARS-CoV-2, the causative agent of COVID-19. These ten antibodies recognise different epitopes of the SARS-CoV-2 Spike glycoprotein, nine of which are SARS-CoV-2-specific and do not cross-react with other human coronaviruses...
Cobra Biologics (Cobra), part of the Cognate BioServices family, an international CDMO manufacturer of biological materials and pharmaceuticals, and Scancell Holdings plc (Scancell), the developer of novel immunotherapies for the treatment of cancer and infectious disease, today announced that they have entered into a collaboration for Cobra to manufacture Scancell’s COVID-19 vaccine....
Renishaw has introduced the Particle Analysis software module for its inVia™ confocal Raman microscope. The module automates the inVia microscope so that it can identify particles on images and then chemically analyse them using Raman spectroscopy. Renishaw's inVia Raman system has a high-quality microscope that is ideal for producing optical images of particles on surfaces....
Are you looking for robust and reproducible columns to evaluate peptides? Do you want to separate oligonucleotides with high resolution? Robust YMC-Triart C18 columns are the perfect choice for reliable and reproducible (U)HPLC analyses of peptides and oligonucleotides with exceptional resolution. The wide temperature- (up to 90°C) and pH-range (1-12) provide increased flexibility....
Phase 3 clinical trials are underway for COVID-19 vaccines, some of which call for an ultra-low freezer for storage and transport. Examples described in a September Wall Street Journal article notes the unusually cold storage temperatures – as low as -80?C – required. Covid-19 vaccine candidates are one of many applications for ultra-low freezers. This post provides you with info on when and how to specify one of these units
Postnova Analytics powerful EAF4 technology combines the principle of Electrical and Asymmetrical Flow Field-Flow Fractionation in just one system. Electrical and Cross Flow Fields can now be applied in one Field-Flow Fractionation (FFF) channel opening up completely new routes for separations which are based on particle size / molar mass and also on particle / molecule charge....
PCR Biosystems, the UK-based PCR experts, have expanded their range of specialist molecular biology kits with the introduction of NGSBIO Library Quant Kit for Illumina®. The new kit contains all the components necessary for accurate and sensitive quantification of DNA libraries prior to next generation sequencing (NGS) with Illumina platforms....
Accelerated Technology Laboratories, Inc. (ATL), a leader in Laboratory Information Management Systems (LIMS), continues the 2020 LIMS Webcast Series on Wednesday, October 14th with LIMS: A Critical Tool for Food Safety Testing. The webcast will focus on the pivotal role of a LIMS in helping food companies combat the challenges faced every day in delivering high quality products....
From October 1, 2020, until January 15, 2021, young researchers not older than 35 years, with an advanced degree, who are working in Europe can apply for the Eppendorf Award for Young European Investigators. This highly prestigious 20,000 EUR prize acknowledges outstanding contributions to biomedical research in Europe based on methods of molecular biology, including novel analytical concepts....
Eppendorf introduces the refrigerated 24-place centrifuge 5425 R, the successor of its popular centrifuge 5424 R. The new device comes with a bundle of improvements, making applications in the field of molecular and cell biology easier than ever. The superior cooling system not only protects temperature-sensitive samples of any kind even at full speed, it is also ready to start immediately with a cool down time of only 8 minutes...
Avacta Group plc, the developer of innovative cancer therapies and diagnostics based on its proprietary Affimer® and pre|CISION™ platforms, is pleased to announce that the BAMS™ assay to detect the SARS-CoV-2 virus has been launched as a research kit by its partner Adeptrix (Beverly, MA, USA) and the assay has been presented by Bruker Scientific (Billerica, MA, USA), a leading mass spectrometer manufacturer, in a new application note...
New Thermo Scientific Tox Explorer Collection provides instruments, columns and consumables with reliable and validated methods for reproducible result. Clinical research, forensic and anti-doping toxicology laboratories facing the challenges of analyzing increasing numbers of analytes in biological matrices, can now easily and rapidly optimize their liquid chromatography-mass spectrometry (LC-MS) methods for targeted screening and quantification....
EKF Diagnostics, the global in vitro diagnostics company, announces that the novel viral transport media PrimeStore® MTM (Molecular Transport Medium) has been successfully evaluated for effective SARS-CoV-2 inactivation in a new study published by Public Health England (PHE). To work safely with live SARS-CoV-2 samples requires the use of high-containment laboratories....
The COVID-19 pandemic is one of the most urgent infectious disease challenges the world has faced in recent history. Presently, few treatment options exist, therefore, the need to evaluate neutralizing antibodies to fight the SARS-CoV-2 virus is at an all-time high. Current screening methods to identify circulating SARS-CoV-2 neutralizing antibodies including the plaque reduction neutralization assay and other live virus cell based tests are inefficient and can require multiple days to complete.,,,
The COVID-19 crisis has led to unparalleled pressure on labs to ramp up capacity for SARS-CoV-2 testing. INTEGRA’s electronic pipettes, pipetting robots and other instruments have helped many labs tackle this challenge of increasing testing capacity while, at the same time, enhancing the reproducibility of results. VOYAGER adjustable tip spacing pipettes are ideal for transferring patient samples from individual collection tubes – either blood collection or swab tubes – to microplates in serological and PCR testing workflows...
AMSBIO announce new additions and certifications for their market-leading range of clinical grade, chemically defined cryopreservation excipient solutions - STEM-CELLBANKER® and HSC-BANKER®. STEM-CELLBANKER® DMSO Free GMP grade is a new chemically defined freezing solution that does not contain DMSO as an anti-freezing agent. It was developed for customers who prefer not to use DMSO-containing cryopreservation solution...
The UK genomic tools developer, RevoluGen Ltd.,has announced new data validating the performance of its high-molecular weight (HMW) DNA extraction kit, Fire Monkey. Scientists at the UK’s Quadram Institute together with collaborators in Pakistan have published positive results from Illumina whole genome sequencing (WGS) for extensively drug-resistant (XDR) Salmonella Typhi characterization in Pakistan, using Fire Monkey....
Gilson has developed a compact, low-cost tube filling system that has the flexibility to fill bottles, tubes, vials, or microplates quickly. With the current pandemic, there is an exponential demand for diagnostic testing of patients for COVID-19, the disease caused by the SARS-CoV-2 virus. Viral transport media (VTM) is a critical component of COVID-19 test kits and is used for the collection, transport, and storage of clinical specimens....
ACCU-FUSE™ Vial Kits manufactured by Worldwide Glass Resources® provide a new level of quality and confidence for trouble-free use of limited volume vials. The ACCU-FUSE™ vial is a glass to glass, sealed in insert, limited volume vial. It can be ordered individually or pre-packaged with closures as a kit. Our current line of 24 kitted options include 11mm Large Opening Crimp, 11mm Snap-Ring, 9mm Screw Thread and 10mm Screw Thread vials. All are offered in both clear and amber....
Inhibiting the growth of harmful bacteria and minimising the threat of cross-contamination is vital in hygiene critical areas within agricultural, pharmaceutical, food processing, educational and health care laboratories. Bacteria commonly encountered in these areas are capable of prolonged survival on most surfaces, in optimal conditions they can reproduce every twenty minutes, spreading rapidly where they dwell....