BioChromato Inc. reports on how Pharmaceutical companies undertaking Absorption, Distribution, Metabolism and Excretion (ADME) studies are benefiting from integrating RAPID Easy Piercing Seals (EPS) into their screening protocols. Optimization of the ADME properties of a drug molecule is one of the most difficult and challenging part of the drug discovery process. The ADME profile of a compound has a major impact on the likelihood of its success as a drug....
Kromek a worldwide supplier of detection technology focusing on the medical, security screening and nuclear markets, announces that it has commenced a £1.25m programme funded by Innovate UK to customise its biological threat-detection solution for the automated detection of all airborne viruses, including COVID-19, to support end-use cases....
Making people stand in front of a scanner to have their body temperature read can result in a large number of false negatives, allowing people with Covid-19 to pass through airports and hospitals undetected. Leading experts in physiology have suggested instead that taking temperature readings of a person’s fingertip and eye would give a significantly better and more reliable reading and help identify those with fever....
Waters Corporation (NYSE:WAT) today announced that its Xevo TQ-XS atmospheric pressure gas chromatography (APGC) mass spectrometry (MS) platform is an accepted alternative for the identification and quantification of dioxins and furans in environmental samples. Dioxins are a byproduct of human industrial activity and their effects on human health are well documented....
BioChromato Inc. has published an interview with the Department of Medicinal Chemistry and Molecular Pharmacology at Purdue University (Indiana, USA) that explains how the Smart Evaporator C1 has assisted them in isolating and purifying novel compounds from DMSO solutions for potential pharmaceutical use. Because the US Federal Drug Administration (FDA) does not approve DMSO formulations for human administration, researchers at Purdue University wanted to synthesise a new Platinum (IV) chloride complex...
Autoscribe Informatics took the opportunity in a recent webinar to discuss the much-misunderstood subject of LIMS validation. Within regulated environments LIMS validation is a vital process, and yet is a subject that is open to many different interpretations. Regulatory bodies throughout the world, such as the US Food and Drug Administration (FDA), require that software systems be tested and proven to work as intended....
Illumina, Inc. is transforming genomic data bottlenecks into catalysts with the launch of Illumina Connected Analytics (ICA). This new and integrated bioinformatics solution provides a comprehensive, private, cloud-based data platform that empowers customers to manage, analyze, and explore large volumes of multi-omic data in a secure, scalable, and flexible environment.
ZEISS introduces ZEISS Solutions Lab, an innovative service, that provides its customers with rapid access to new applications for their microscopy systems or correlative microscopy suites. ZEISS Solutions Lab enables customers to select, or to drive demand for module-based workflows built on ZEISS software packages for a wide variety of requirements specific to their research needs...
New research on the structure and dynamics of a branched form of DNA called a three-way junction could lead to more effectively targeted treatments for degenerative disorders like Huntington’s Disease, scientists say. In a new paper published in the journal Nature Communications, chemists from the University of Glasgow show for the first time how three-way DNA junctions undergo unexpected rearrangements in their structure....
Excalibur Healthcare Services Ltd, a leading UK-based provider of high-quality medical products and services, has announced that its Rapid SARS COV-2 Antigen Screening test is the first ever lateral flow antigen test to receive regulatory approval for use in mass screening for COVID-19 in asymptomatic, pre-symptomatic and symptomatic populations....
ZEISS announces that it has formed a research collaboration partnership with the Max Planck Florida Institute for Neuroscience (MPFI). Using an LSM 980 NLO next generation confocal microscope supplied by ZEISS, MPFI will investigate using implanted GRadient INdex (GRIN) lenses in combination with the Airyscan 2 area detector for deep brain functional neuroscience research....
Upgrading a microscope with a motorized stage enhances a microscope’s capability by allowing for rapid, smooth, and highly repeatable sample movement. This can be difficult to achieve or impractical, using a manual stage, especially when the experiment requires the operator to perform repeated, precise, and accurate movements over a long time period. Motorized stages allow the user to pre-program movements, set and save location points for return inspection, and integrate the stage’s positioning within the imaging process....
Mogrify Limited, a UK company aiming to transform the development of ex vivo cell therapies and pioneer the field of in vivo reprogramming therapies, and the MRC Laboratory of Molecular Biology (LMB), a world-class research laboratory dedicated to understanding important biological processes at the molecular level, today announced an exploratory research collaboration. The project aims to develop novel protein expression systems by leveraging recent advances in direct cell reprogramming...
Teknova, a leading manufacturer of cell culture media and supplements, purification buffers, and molecular biology reagents, has completed the process of FDA notification for its Active Viral Transport Medium (ATM). ATM is a room temperature-stable version of Teknova’s CDC formulation Viral Transport Medium (VTM)and is manufactured under GMP conditions in compliance with ISO 13485 standards....
JEOL USA awarded two Grand Prizes to winners of its 2020 Electron Microscopy Image Contest, and kicked off its 2021 Image Contest at the beginning of the new year. The annual contest showcases JEOL microscope users’ artistically or esthetically pleasing images with good composition, sharp focus, and technical competency, especially in the use of accelerating voltage...
AMSBIO has introduced a series of kit products based upon high-quality SARS-CoV-2 antigen proteins to improve the efficiency of anti-SARS-CoV-2 drugs and vaccines development. These new kit products include SARS-CoV-2 inhibitor screening kits, antibody titer serologic assay kits, antigen detection kit and antigen pre-coated plates....
In line with the need for pharmaceutical research, cell and gene therapy, vaccine production and biobanking laboratories for dependable sample protection, the new series of controlled-rate freezers from Thermo Fisher Scientific provides precise, repeatable freezing capabilities, while enhancing data traceability to support GMP and 21 CFR part 11 requirements.
Scientists sequencing virus samples from the first confirmed cases of COVID-19 in Scotland (and through the first wave) have found evidence of community transmission, driven by multiple introductions through international travel, as early as February 2020. In new research, led by the University of Glasgow and published in Nature Microbiology, researchers have been able to confirm that SARS-CoV-2, the virus which causes COVID-19, had multiple introductions to Scotland in early 2020, mainly from European countries such as Italy and Spain....
Autogen, Inc. is pleased to announce the introduction of their newest fully automated workflow, the NeXTRACT 48. The NeXTRACT 48 is designed for the rapid extraction of viral DNA and/or RNA from a variety of samples including VTM, UVT, and sputum. This workflow processes 48 samples in 20 minutes and can easily process 800 samples or more per day, providing quick, consistent, and reproducible results....
Through this Acquisition, PerkinElmer will grow its portfolio of advanced infectious disease testing solutions to include tuberculosis detection to better serve customers around the world. Moreover, the deal will enable PerkinElmer to combine its channel expertise and leading workflow and testing capabilities with Oxford Immunotec’s leading proficiencies in T cell immunology with its proprietary test kits for latent tuberculosis....
Ziath has introduced a new version of DataPaq 5 (DP5) - its versatile web-based software product that allows scientists to directly read 2D-barcoded tubes at the point of sample storage or retrieval. DPDP5 offers a convenient way to use a 2D barcoded tube or rack scanner anywhere across a laboratory or an organisation’s site where a suitable laptop or computer is available. Thanks to its web server design, DP5 will run on both Microsoft and Apple operating systems....
Finneran Porvair has introduced new Convenience Kits for Per- and Polyfluoroalkyl substances (PFAS) testing. Because Per- and Polyfluoroalkyl substances don't break down they can accumulate over time in the environment and in the human body. There is increasing evidence that exposure to PFAS can adversely affect human health. As a result, regulatory bodies are increasingly legislating that many materials should be tested to ensure that they contain no traces of PFAS or that the traces are below allowed legal limits....