In this application note the drug-to-antibody ratio (DAR) of a cys-linked ADC-mimic is determined using online native HIC-MS. Using the innovative BioPro HIC BF column and a direct coupling to the mass spectrometer even degraded payloads can be detected. The application also demonstrates how to overcome the high salt concentrations which are necessary for HIC methods....
AMSBIO has published an interview with researchers at Yamaguchi University Graduate School of Medicine, Department of Gastroenterology and Hepatology, Japan, that covers their groundbreaking work to develop cell regeneration therapies for liver cirrhosis. The interview covers the involvement of the Graduate School of Medicine in the development of StemFit® for Mesenchymal Stem Cell (MSC), a new chemically defined medium which minimizes the risk of hazardous animal derived ingredients....
Excellims Corporation (Excellims), a leading provider of high performance ion mobility spectrometers (HPIMS) / mass spectrometry (MS), has won The Analytical Scientist Innovation Award (TASIA) 2020. TASIAs showcase the technologies driving progress in measurement science. The award recognizes that HPIMS brings the power of state-of-the-art Ion Mobility out of the lab: enabling high resolution and sensitive chemical detection at the point of need...
Autoscribe Informatics, a leading global laboratory informatics provider, announced the release of a new white paper examining the role of a Laboratory Information Management System (LIMS) in supporting ISO17025 accreditation. The white paper explores the ways in which a Laboratory Information Management System (LIMS) can play a key role in achieving, maintaining, and benefiting from ISO17025 accreditation.
Cell Guidance Systems Ltd, a specialist in exosome research reagents and services, has announced the launch of a new product for the purification of exosomes from blood and other samples. The Exo-spin™ 96 exosome purification kit allows researchers to purify exosome samples in the standard 96 well plate format. The Exo-spin 96 kit is based on the increasingly popular size exclusion chromatography (SEC) method of exosome purification which is now used by most exosome research labs....
Lonza and the Vaccines Manufacturing and Innovation Centre (VMIC), a not-for-profit organization established to provide the UK’s first strategic vaccine development and advanced manufacturing capability, announced a project to implement the MODA-EM™ Solution to automate quality control (QC) in the new facility. VMIC plans to implement the MODA-EM™ Solution as part of its strategy to develop a state-of-the-art manufacturing center due to open in 2021 – fast-tracked to open a year ahead of schedule...
Micronic launches an optional Docking Station for its CS500, CS510 and CS520 Screw Cap Recappers. Using the Docking Station in combination with the Screw Cap Recappers, a consistent capping and decapping action is assured, allowing research laboratories to recap 96-well, 48-well and 24-well format sample storage tubes securely and uniformly for an optimal sealing performance...
Accelerated Technology Laboratories, Inc. (ATL), a leader in Laboratory Information Management Systems (LIMS), kicks off the 2021 LIMS Webcast Series on Wednesday, January 20th with LIMS – On-Premises or SaaS (Cloud) Deployment: Which is Right for My Laboratory? When selecting a LIMS today, organizations have deployment options. Traditionally, laboratories deployed the LIMS software on-site...
TESTA Analytical Solutions has published a technical report that evaluates an exciting new liquid flowmeter device designed to provide continuous real-time monitoring of the pump flow rate of any liquid chromatography system. High Performance Liquid Chromatography (HPLC) is nowadays one of the most widely used techniques in analytical chemistry. The range of applications soluble using HPLC covers a vast range of sample types, concentrations and compositions....
Abbott has received CE Mark for its new quantitative SARS-CoV-2 IgG (Immunoglobulin G) lab-based serology test. IgG antibody testing that gives a quantitative result (measuring the amount of antibodies) provides important insights to people as they recover from COVID-19 and help evaluate a person's immune response to a vaccine. Countries around the world are preparing for the authorisation and the distribution of COVID-19 vaccines....
Illumina, Inc. and Harvard Pilgrim Health Care announce a risk-sharing agreement to make whole-genome sequencing (WGS) available to certain Harvard Pilgrim members, effective January 1, 2021. The program will leverage WGS to support faster diagnoses of genetic diseases in children, potentially eliminating the long, costly diagnostic odyssey experienced by many families, with the goal of improving patient outcomes....
Once an effective COVID19 vaccine is available in the required quantities and is to be delivered to the vaccination centres, a specific logistical task also needs to be addressed: The vaccine must be transported at a temperature of at least -70oC to -80oC and stored on site at the vaccination centre. L&R Kältetechnik has developed a safe, flexible and economical concept for this demanding type of deep-freeze storage: a deep-freeze storage system that is installed in an industrial container...
The Multicell PLUS is an exciting addition to the Asynt range of pressure reactors, offering scientists an extremely flexible and customisable device for screening chemical reactions under high pressure conditions. With its own unique safety-locking mechanism and robust, adjustable support frame / lifting platform option, the Multicell PLUS high-pressure reactor sets a new benchmark for operator safety, all-round accessibility and ease-of-use...
ZEISS is expanding its imaging technology capabilities with 3D and big image data software by acquiring a majority stake in the imaging business of arivis. With this investment, ZEISS is further strengthening its software competencies and market position in 3D image visualization, image processing, and analysis software for research microscopy. Both companies have a long-standing collaboration and strategic partnership, as arivis has been an important development partner for ZEISS for more than seven years..
Agilent Technologies Inc. has announced its clinical informatics platform Alissa Interpret has been adopted by the North West Genomic Laboratory Hub (NW GLH) based in Manchester and Liverpool, part of Manchester University NHS Foundation Trust, England. The NW GLH and its partners are responsible for delivering genomic testing across the whole of the North West....
EKF Diagnostics, the global in vitro diagnostics company, announces that it has introduced one of the first tests to precisely measure levels of COVID-19 neutralizing antibodies in individuals. Unlike other antibody tests, the Kantaro COVID-SeroKlir SARS-CoV-2 IgG antibody test kit determines both the presence and specific quantities of human IgG antibodies to the SARS-CoV-2 virus. This enables a broad range of COVID-19 applications...
Porvair Sciences will exhibit its latest specialist microplates and microplate instrumentation at the forthcoming SLAS 2021 Digital International Conference and Exhibition (January 25-27th 2021). Microplates product manager - Krzysztof Kielmann commented "A particular focus of our virtual exhibit will be specialist microplates and instrumentation for labs supporting the global COVID-19 testing effort....
The Differential Refractive Index (DRI) detector from Testa Analytical Solution e.K offers unmatched accuracy and reliability for determination of absolute concentration and total mass balance in Gel Permeation Chromatography / Size Exclusion Chromatography (GPC/SEC) applications. The baseline signal stability of any liquid chromatography detector is very important, as it is a limiting factor in peak determination....
eNUVIO announce the release of the first completely reusable 3D cell culture microplate on the market. Scientific research currently consumes high-volumes of single-use plastics - from serological pipettes and pipette tips to vials and culture microplates - these are just a few of the many plastic items thrown in the garbage in labs everyday. eNUVIO’s completely reusable EB-Plate comes to the market at the right time as the demand for 3D cell culture microplates...
Merck announce the launch of its new Scepter™ 3.0 handheld automated cell counter, a solution that enables convenient, on-demand cell volume, cell diameter and cell concentration data. The device uses precision microfluidics to measure and count cells via electrical impedance within 30 seconds. The Scepter™ 3.0 cell counter offers researchers true automation without the risk of error that accompanies vision-based systems, using a combination of analog and digital hardware for sensing, signal processing, data storage, and graphical display....
With the release of ZEISS Lattice Lightsheet 7, ZEISS places a turn-key lattice light sheet instrument at the disposal of the life science research community. Based on the pioneering research and developments of Ernst H. K. Stelzer while at EMBL, Heidelberg, on light sheet technology and of Nobel laureate Eric Betzig while at the Janelia Research Campus of HHMI on structuring light sheets as optical lattices to render them thinner and longer...
Agilent Technologies Inc. has announced a new ICP-MS instrument, the Agilent 7850 ICP-MS System, that provides new smart tools to minimize common time traps that can affect ICP-MS analysis workflows.Building on decades of innovation, the 7850 ICP-MS combines market-leading performance with new smart software features that bring advanced capabilities to the routine ICP-MS laboratory....
In this application note the drug-to-antibody ratio (DAR) of a cys-linked ADC-mimic is determined using online native HIC-MS. Using the innovative BioPro HIC BF column and a direct coupling to the mass spectrometer even degraded payloads can be detected. The application also demonstrates how to overcome the high salt concentrations which are necessary for HIC methods....
AMSBIO has published an interview with researchers at Yamaguchi University Graduate School of Medicine, Department of Gastroenterology and Hepatology, Japan, that covers their groundbreaking work to develop cell regeneration therapies for liver cirrhosis. The interview covers the involvement of the Graduate School of Medicine in the development of StemFit® for Mesenchymal Stem Cell (MSC), a new chemically defined medium which minimizes the risk of hazardous animal derived ingredients....
Excellims Corporation (Excellims), a leading provider of high performance ion mobility spectrometers (HPIMS) / mass spectrometry (MS), has won The Analytical Scientist Innovation Award (TASIA) 2020. TASIAs showcase the technologies driving progress in measurement science. The award recognizes that HPIMS brings the power of state-of-the-art Ion Mobility out of the lab: enabling high resolution and sensitive chemical detection at the point of need...
Autoscribe Informatics, a leading global laboratory informatics provider, announced the release of a new white paper examining the role of a Laboratory Information Management System (LIMS) in supporting ISO17025 accreditation. The white paper explores the ways in which a Laboratory Information Management System (LIMS) can play a key role in achieving, maintaining, and benefiting from ISO17025 accreditation.
Cell Guidance Systems Ltd, a specialist in exosome research reagents and services, has announced the launch of a new product for the purification of exosomes from blood and other samples. The Exo-spin™ 96 exosome purification kit allows researchers to purify exosome samples in the standard 96 well plate format. The Exo-spin 96 kit is based on the increasingly popular size exclusion chromatography (SEC) method of exosome purification which is now used by most exosome research labs....
Lonza and the Vaccines Manufacturing and Innovation Centre (VMIC), a not-for-profit organization established to provide the UK’s first strategic vaccine development and advanced manufacturing capability, announced a project to implement the MODA-EM™ Solution to automate quality control (QC) in the new facility. VMIC plans to implement the MODA-EM™ Solution as part of its strategy to develop a state-of-the-art manufacturing center due to open in 2021 – fast-tracked to open a year ahead of schedule...
Micronic launches an optional Docking Station for its CS500, CS510 and CS520 Screw Cap Recappers. Using the Docking Station in combination with the Screw Cap Recappers, a consistent capping and decapping action is assured, allowing research laboratories to recap 96-well, 48-well and 24-well format sample storage tubes securely and uniformly for an optimal sealing performance...
Accelerated Technology Laboratories, Inc. (ATL), a leader in Laboratory Information Management Systems (LIMS), kicks off the 2021 LIMS Webcast Series on Wednesday, January 20th with LIMS – On-Premises or SaaS (Cloud) Deployment: Which is Right for My Laboratory? When selecting a LIMS today, organizations have deployment options. Traditionally, laboratories deployed the LIMS software on-site...
TESTA Analytical Solutions has published a technical report that evaluates an exciting new liquid flowmeter device designed to provide continuous real-time monitoring of the pump flow rate of any liquid chromatography system. High Performance Liquid Chromatography (HPLC) is nowadays one of the most widely used techniques in analytical chemistry. The range of applications soluble using HPLC covers a vast range of sample types, concentrations and compositions....
Abbott has received CE Mark for its new quantitative SARS-CoV-2 IgG (Immunoglobulin G) lab-based serology test. IgG antibody testing that gives a quantitative result (measuring the amount of antibodies) provides important insights to people as they recover from COVID-19 and help evaluate a person's immune response to a vaccine. Countries around the world are preparing for the authorisation and the distribution of COVID-19 vaccines....
Illumina, Inc. and Harvard Pilgrim Health Care announce a risk-sharing agreement to make whole-genome sequencing (WGS) available to certain Harvard Pilgrim members, effective January 1, 2021. The program will leverage WGS to support faster diagnoses of genetic diseases in children, potentially eliminating the long, costly diagnostic odyssey experienced by many families, with the goal of improving patient outcomes....
Once an effective COVID19 vaccine is available in the required quantities and is to be delivered to the vaccination centres, a specific logistical task also needs to be addressed: The vaccine must be transported at a temperature of at least -70oC to -80oC and stored on site at the vaccination centre. L&R Kältetechnik has developed a safe, flexible and economical concept for this demanding type of deep-freeze storage: a deep-freeze storage system that is installed in an industrial container...
The Multicell PLUS is an exciting addition to the Asynt range of pressure reactors, offering scientists an extremely flexible and customisable device for screening chemical reactions under high pressure conditions. With its own unique safety-locking mechanism and robust, adjustable support frame / lifting platform option, the Multicell PLUS high-pressure reactor sets a new benchmark for operator safety, all-round accessibility and ease-of-use...
ZEISS is expanding its imaging technology capabilities with 3D and big image data software by acquiring a majority stake in the imaging business of arivis. With this investment, ZEISS is further strengthening its software competencies and market position in 3D image visualization, image processing, and analysis software for research microscopy. Both companies have a long-standing collaboration and strategic partnership, as arivis has been an important development partner for ZEISS for more than seven years..
Agilent Technologies Inc. has announced its clinical informatics platform Alissa Interpret has been adopted by the North West Genomic Laboratory Hub (NW GLH) based in Manchester and Liverpool, part of Manchester University NHS Foundation Trust, England. The NW GLH and its partners are responsible for delivering genomic testing across the whole of the North West....
EKF Diagnostics, the global in vitro diagnostics company, announces that it has introduced one of the first tests to precisely measure levels of COVID-19 neutralizing antibodies in individuals. Unlike other antibody tests, the Kantaro COVID-SeroKlir SARS-CoV-2 IgG antibody test kit determines both the presence and specific quantities of human IgG antibodies to the SARS-CoV-2 virus. This enables a broad range of COVID-19 applications...
Porvair Sciences will exhibit its latest specialist microplates and microplate instrumentation at the forthcoming SLAS 2021 Digital International Conference and Exhibition (January 25-27th 2021). Microplates product manager - Krzysztof Kielmann commented "A particular focus of our virtual exhibit will be specialist microplates and instrumentation for labs supporting the global COVID-19 testing effort....
The Differential Refractive Index (DRI) detector from Testa Analytical Solution e.K offers unmatched accuracy and reliability for determination of absolute concentration and total mass balance in Gel Permeation Chromatography / Size Exclusion Chromatography (GPC/SEC) applications. The baseline signal stability of any liquid chromatography detector is very important, as it is a limiting factor in peak determination....
eNUVIO announce the release of the first completely reusable 3D cell culture microplate on the market. Scientific research currently consumes high-volumes of single-use plastics - from serological pipettes and pipette tips to vials and culture microplates - these are just a few of the many plastic items thrown in the garbage in labs everyday. eNUVIO’s completely reusable EB-Plate comes to the market at the right time as the demand for 3D cell culture microplates...
Merck announce the launch of its new Scepter™ 3.0 handheld automated cell counter, a solution that enables convenient, on-demand cell volume, cell diameter and cell concentration data. The device uses precision microfluidics to measure and count cells via electrical impedance within 30 seconds. The Scepter™ 3.0 cell counter offers researchers true automation without the risk of error that accompanies vision-based systems, using a combination of analog and digital hardware for sensing, signal processing, data storage, and graphical display....
With the release of ZEISS Lattice Lightsheet 7, ZEISS places a turn-key lattice light sheet instrument at the disposal of the life science research community. Based on the pioneering research and developments of Ernst H. K. Stelzer while at EMBL, Heidelberg, on light sheet technology and of Nobel laureate Eric Betzig while at the Janelia Research Campus of HHMI on structuring light sheets as optical lattices to render them thinner and longer...
Agilent Technologies Inc. has announced a new ICP-MS instrument, the Agilent 7850 ICP-MS System, that provides new smart tools to minimize common time traps that can affect ICP-MS analysis workflows.Building on decades of innovation, the 7850 ICP-MS combines market-leading performance with new smart software features that bring advanced capabilities to the routine ICP-MS laboratory....