While the cultured meat industry is gaining momentum, scaling up the production process and reducing the cost remain key challenges. The primary focus of the collaboration between Merck and the two universities will be the development of next generation, scalable bioreactor designs that can support meat and seafood manufacture on a commercial scale....
The first study of its kind reports on the enhancement of skin permeability of risperidone (RIS) using eutectic systems. A recent study undertaken at the University of Petra in Jordan describes for the first time the formation of room temperature therapeutic deep eutectic solvent (THEDES) of RIS, an antipsychotic drug that is used in the treatment of schizophrenia, mixed and manic states associated with bipolar disorder and irritability in children and adolescents with autism....
Malvern Panalytical was delighted to welcome His Royal Highness The Earl of Wessex to its Malvern, Worcestershire, headquarters. Malvern Panalytical was selected for the Royal visit, amongst a small number of other Worcestershire businesses, primarily because of its scientific and technical contribution to the development of medicines and vaccines to treat and prevent COVID-19...
SP Scientific Products (SP) has announced one of the world’s largest simultaneous installations of commercial lyophilizers for use in the production of diagnostic tests. The order, for SP lyophilizers, was made last year by a leading global healthcare company in response to the need for an increase in SARS-CoV-2 testing. With the urgency of the pandemic and requirement for speed, SP was able to complete the delivery of 16 freeze dryers – including manufacturing, testing, and installation - in just four months...
To meet the high demand for lipids, a key component of mRNA-based vaccines and therapeutics, Merck, a leading science and technology company, has launched a new, high-purity synthetic cholesterol product, nine months ahead of schedule. “Tapping into two decades’ experience of developing and manufacturing high-quality lipids, we designed a proprietary process to bring our new SAFC® synthetic cholesterol product to market nearly a year early,” said Andrew Bulpin...
Moderna, a biotechnology company pioneering messenger RNA (mRNA) therapeutics and vaccines, and Samsung Biologics, a leading global CDMO providing a fully integrated end-to-end contract development and manufacturing service, today announced a Manufacturing Services and Supply Agreement in which Samsung Biologics will provide large scale, commercial fill-finish manufacturing for mRNA-1273, Moderna’s COVID-19 vaccine....
The Archaeology Department of the University of Liverpool has carried out two ground-breaking projects that have improved our understanding of how human culture developed in ancient times. Playing a key role in that research has been the Keyence VHX-7000 Series Digital Microscope, the world's first 4K ultra high accuracy microscope. Elizabeth Thomas, an Archaeology PhD student at the university, had the opportunity to use the Keyence digital microscope when conducting research...
A new eBook from Freeman Technology, a Micromeritics company and global leader in powder characterisation, explores the application of powder flow measurements for monitoring and optimising granulation processes. Granulation is a vital unit operation for many industries, notably the pharmaceutical sector, but endpoint detection and scale-up remain a challenge. ‘Powder Flow Testing for Granulation Processes’ focuses on the value of bulk powder characterisation...
Due to the corona crisis hand sanitizer became part of our daily routine. Alcohol-based hand sanitizers with at least 60 to 95% alcohol is recommended by the World Health Organisation (WHO), with the main components being ethanol, isopropyl alcohol (IPA) and/or n-propanol. To determine the effectiveness and impurities of the hand sanitizer a GC analysis can be performed. This analysis faces many challenges since hand sanitizer is made in a water matrix, which is a difficult matrix for Gas Chromatography....
Gilson and Acumium announce their collaboration to develop contemporary technologies and tools for academic and industrial cell culture laboratories. The partnership aims to bring scientists new digital solutions for managing cell culture protocols, data collection and maximizing data use. Both companies see these advances to be of particular importance to pharmaceutical research and the burgeoning cell-based cancer therapeutics arena...
A team of international scientists have identified key cellular factors that are crucial for the infection of SARS-CoV-2, the virus that causes COVID-19. The study – led by the Universities of Glasgow and Oxford and the Rosalind Franklin Institute and published in Molecular Cell – provides crucial new insights into the SARS-CoV-2 life cycle, revealing new pathways to target the virus within host cells and leading the way for potential new treatment options as we move into the next phase of the pandemic....
Collaboration between scientists and technologists helps to advance cryo-electron microscopy and life sciences research. TESCAN ORSAY HOLDING a.s. announces a joint research collaboration agreement between the Institute of Molecular Genetics of the Academy of Sciences of the Czech Republic (IMG AS CR) and leading scientific instrumentation companies in Europe. Observing viruses or proteins in detail has been the dream of scientists world-wide for years....
Method of choice: The combination of size exclusion chromatography (SEC) and light scattering detection (LS) determines molecular weight, especially for higher molecular species such as aggregates or oligomers. As an additional plus sample size and topology can also be revealed. Special attention needs to be turned to the quality of SEC columns in order to provide signals unaffected by spikes. YMC’s SEC columns support LS-detection perfectly due to a high level of inertness...
Waldner is expanding its operations in India with a strong partner: GD Lab Solutions Pvt. Ltd. and Waldner, two long-standing partners, are set to merge and combine their competencies and expertise. Waldner is a global market-leading company in the development and manufacture of laboratory fume hoods, room air controls, service supply systems, and laboratory furniture....
The addition of the new NovaSeq 6000 to Macrogen Europe’s range of industry-leading NGS and Sanger sequencing platforms comes at time of growing demand for its DNA sequencing services, for example from biomarker and drug discovery applications in oncology, immunology and metagenomics. The increased sequencing capacity helps clients in industry, academia and research institutes keep their projects on track....
BioChromato Inc. has published a report describing how their ionRocket sample preparation device, used in combination with Direct Analysis in Real Time Mass Spectrometry (DART-MS) and Kendrick Mass Defect (KMD) analysis, provides a valuable new tool for chain analysis of fluoroelastomers. Because of their excellent heat, chemical and abrasion resistance - fluoropolymers are widely used in automotive parts and many other industrial products....
At Edwards, beyond a broad range of pumps, we also offer other vacuum solutions which contribute to an effective and safe vacuum configuration. To make sure you operate, configure and maintain your vacuum set-up in the best way possible you should ask yourself 5 quick questions. Run through the checklist here...
Look at every stage of the development of COVID-19 vaccines and you will find a commonality — automation. From genome sequencing to clinical trials and mass production, the development speed was made possible using highly repeatable automated processes. Here Matthew Dean, sales engineer for medical applications at precision motor and drives specialist maxon UK and Ireland, discusses how improvements in motors and drive systems have enabled the development of the automated technology needed to address today’s challenges....
Over the past 20 years, Worldwide Glass Resources® has emerged as a leader in custom vial design, engineering and manufacturing for global Distributors, OEM’s, Diagnostic and Packaging Companies. From personalized custom barcoded high recovery vials for Pharmaceutical Purification and Compound Libraries to custom vials for Covid Kits, our in-house engineering and production teams are ready to assist with your next vial project....
NovAliX, a drug discovery-focused Contract Research Organization (CRO), announces the expansion of its cryogenic electron microscopy (cryo-EM) technology capability. NovAliX will benefit from the implementation at its premises of Thermo Fisher Scientific’s high-resolution microscope, the Thermo Scientific Glacios Cryo-TEM, with additional micro-electron diffraction (microED) capabilities for solving protein and small molecule structures using nanoscale crystals....
Researchers from the School of Chemistry at the University of St Andrews (UK) are using a DrySyn Spiral Evaporator from Asynt to help synthesize novel reactive colloidal nanoparticles that present an exciting tool to create a new generation of 'smart' nanomaterials. The unique properties of nanomaterials mean that potential applications extend from use in smart drug delivery systems through to new catalysts and helping to deliver greater efficiency in solar cells....
Through this acquisition, PerkinElmer will be able to grow its overall Diagnostics business and specifically its immunodiagnostics segment. Moreover, the deal will enable PerkinElmer to combine its channel expertise and testing capabilities with IDS’s best-in-class chemiluminescence products in endocrinology, autoimmunity and infectious diseases to better serve customers around the world....
While the cultured meat industry is gaining momentum, scaling up the production process and reducing the cost remain key challenges. The primary focus of the collaboration between Merck and the two universities will be the development of next generation, scalable bioreactor designs that can support meat and seafood manufacture on a commercial scale....
The first study of its kind reports on the enhancement of skin permeability of risperidone (RIS) using eutectic systems. A recent study undertaken at the University of Petra in Jordan describes for the first time the formation of room temperature therapeutic deep eutectic solvent (THEDES) of RIS, an antipsychotic drug that is used in the treatment of schizophrenia, mixed and manic states associated with bipolar disorder and irritability in children and adolescents with autism....
Malvern Panalytical was delighted to welcome His Royal Highness The Earl of Wessex to its Malvern, Worcestershire, headquarters. Malvern Panalytical was selected for the Royal visit, amongst a small number of other Worcestershire businesses, primarily because of its scientific and technical contribution to the development of medicines and vaccines to treat and prevent COVID-19...
SP Scientific Products (SP) has announced one of the world’s largest simultaneous installations of commercial lyophilizers for use in the production of diagnostic tests. The order, for SP lyophilizers, was made last year by a leading global healthcare company in response to the need for an increase in SARS-CoV-2 testing. With the urgency of the pandemic and requirement for speed, SP was able to complete the delivery of 16 freeze dryers – including manufacturing, testing, and installation - in just four months...
To meet the high demand for lipids, a key component of mRNA-based vaccines and therapeutics, Merck, a leading science and technology company, has launched a new, high-purity synthetic cholesterol product, nine months ahead of schedule. “Tapping into two decades’ experience of developing and manufacturing high-quality lipids, we designed a proprietary process to bring our new SAFC® synthetic cholesterol product to market nearly a year early,” said Andrew Bulpin...
Moderna, a biotechnology company pioneering messenger RNA (mRNA) therapeutics and vaccines, and Samsung Biologics, a leading global CDMO providing a fully integrated end-to-end contract development and manufacturing service, today announced a Manufacturing Services and Supply Agreement in which Samsung Biologics will provide large scale, commercial fill-finish manufacturing for mRNA-1273, Moderna’s COVID-19 vaccine....
The Archaeology Department of the University of Liverpool has carried out two ground-breaking projects that have improved our understanding of how human culture developed in ancient times. Playing a key role in that research has been the Keyence VHX-7000 Series Digital Microscope, the world's first 4K ultra high accuracy microscope. Elizabeth Thomas, an Archaeology PhD student at the university, had the opportunity to use the Keyence digital microscope when conducting research...
A new eBook from Freeman Technology, a Micromeritics company and global leader in powder characterisation, explores the application of powder flow measurements for monitoring and optimising granulation processes. Granulation is a vital unit operation for many industries, notably the pharmaceutical sector, but endpoint detection and scale-up remain a challenge. ‘Powder Flow Testing for Granulation Processes’ focuses on the value of bulk powder characterisation...
Due to the corona crisis hand sanitizer became part of our daily routine. Alcohol-based hand sanitizers with at least 60 to 95% alcohol is recommended by the World Health Organisation (WHO), with the main components being ethanol, isopropyl alcohol (IPA) and/or n-propanol. To determine the effectiveness and impurities of the hand sanitizer a GC analysis can be performed. This analysis faces many challenges since hand sanitizer is made in a water matrix, which is a difficult matrix for Gas Chromatography....
Gilson and Acumium announce their collaboration to develop contemporary technologies and tools for academic and industrial cell culture laboratories. The partnership aims to bring scientists new digital solutions for managing cell culture protocols, data collection and maximizing data use. Both companies see these advances to be of particular importance to pharmaceutical research and the burgeoning cell-based cancer therapeutics arena...
A team of international scientists have identified key cellular factors that are crucial for the infection of SARS-CoV-2, the virus that causes COVID-19. The study – led by the Universities of Glasgow and Oxford and the Rosalind Franklin Institute and published in Molecular Cell – provides crucial new insights into the SARS-CoV-2 life cycle, revealing new pathways to target the virus within host cells and leading the way for potential new treatment options as we move into the next phase of the pandemic....
Collaboration between scientists and technologists helps to advance cryo-electron microscopy and life sciences research. TESCAN ORSAY HOLDING a.s. announces a joint research collaboration agreement between the Institute of Molecular Genetics of the Academy of Sciences of the Czech Republic (IMG AS CR) and leading scientific instrumentation companies in Europe. Observing viruses or proteins in detail has been the dream of scientists world-wide for years....
Method of choice: The combination of size exclusion chromatography (SEC) and light scattering detection (LS) determines molecular weight, especially for higher molecular species such as aggregates or oligomers. As an additional plus sample size and topology can also be revealed. Special attention needs to be turned to the quality of SEC columns in order to provide signals unaffected by spikes. YMC’s SEC columns support LS-detection perfectly due to a high level of inertness...
Waldner is expanding its operations in India with a strong partner: GD Lab Solutions Pvt. Ltd. and Waldner, two long-standing partners, are set to merge and combine their competencies and expertise. Waldner is a global market-leading company in the development and manufacture of laboratory fume hoods, room air controls, service supply systems, and laboratory furniture....
The addition of the new NovaSeq 6000 to Macrogen Europe’s range of industry-leading NGS and Sanger sequencing platforms comes at time of growing demand for its DNA sequencing services, for example from biomarker and drug discovery applications in oncology, immunology and metagenomics. The increased sequencing capacity helps clients in industry, academia and research institutes keep their projects on track....
BioChromato Inc. has published a report describing how their ionRocket sample preparation device, used in combination with Direct Analysis in Real Time Mass Spectrometry (DART-MS) and Kendrick Mass Defect (KMD) analysis, provides a valuable new tool for chain analysis of fluoroelastomers. Because of their excellent heat, chemical and abrasion resistance - fluoropolymers are widely used in automotive parts and many other industrial products....
At Edwards, beyond a broad range of pumps, we also offer other vacuum solutions which contribute to an effective and safe vacuum configuration. To make sure you operate, configure and maintain your vacuum set-up in the best way possible you should ask yourself 5 quick questions. Run through the checklist here...
Look at every stage of the development of COVID-19 vaccines and you will find a commonality — automation. From genome sequencing to clinical trials and mass production, the development speed was made possible using highly repeatable automated processes. Here Matthew Dean, sales engineer for medical applications at precision motor and drives specialist maxon UK and Ireland, discusses how improvements in motors and drive systems have enabled the development of the automated technology needed to address today’s challenges....
Over the past 20 years, Worldwide Glass Resources® has emerged as a leader in custom vial design, engineering and manufacturing for global Distributors, OEM’s, Diagnostic and Packaging Companies. From personalized custom barcoded high recovery vials for Pharmaceutical Purification and Compound Libraries to custom vials for Covid Kits, our in-house engineering and production teams are ready to assist with your next vial project....
NovAliX, a drug discovery-focused Contract Research Organization (CRO), announces the expansion of its cryogenic electron microscopy (cryo-EM) technology capability. NovAliX will benefit from the implementation at its premises of Thermo Fisher Scientific’s high-resolution microscope, the Thermo Scientific Glacios Cryo-TEM, with additional micro-electron diffraction (microED) capabilities for solving protein and small molecule structures using nanoscale crystals....
Researchers from the School of Chemistry at the University of St Andrews (UK) are using a DrySyn Spiral Evaporator from Asynt to help synthesize novel reactive colloidal nanoparticles that present an exciting tool to create a new generation of 'smart' nanomaterials. The unique properties of nanomaterials mean that potential applications extend from use in smart drug delivery systems through to new catalysts and helping to deliver greater efficiency in solar cells....
Through this acquisition, PerkinElmer will be able to grow its overall Diagnostics business and specifically its immunodiagnostics segment. Moreover, the deal will enable PerkinElmer to combine its channel expertise and testing capabilities with IDS’s best-in-class chemiluminescence products in endocrinology, autoimmunity and infectious diseases to better serve customers around the world....