New Family of UltraPerformance LC Columns Pushes the Limits of Separation Efficiency and Throughput. Waters Corporation (NYSE:WAT) today introduced CORTECS™ Columns, a new family of 1.6 micron solid-core UltraPerformance LC® Columns that set a new standard in LC column performance. The higher efficiency brought to chromatography with CORTECS Columns allows laboratories to produce greater amounts of information faster with every chromatographic separation...
INTEGRA has released a new video demonstrating a solid phase extraction (SPE) microplate method for reproducible, high throughput isolation of high-quality DNA-free total RNA.
Large scale gene expression screening projects require reliable high-throughput methods to isolate high quality RNA from a large number of samples. To meet this need, a growing number of commercial 96-well format RNA isolation kits are now available. Typically such kits are compatible with commonly used 96-well plate vacuum manifolds enabling the extraction (isolation) procedure to be accelerated...
A new application note from Porvair Sciences details a protocol for its Chromatrap® ChIP assay kit that has been developed to enrich epigenetic marks from primary human tissue cells.
Chromatrap® Pro-A, the novel solid-based matrix for chromatin immunoprecipitation assays (ChIP) has been successfully used for isolation of high quality chromatin from difficult biopsy material. Focusing on an application to precipitate epigenetic marks from primary endometrial stromal cells - results show high abundant epigenetic marks from 1 million cells isolated from a tissue biopsy, with selective amplification of positive gene targets relative to negative IgG and negative gene loci....
At ASMS Waters is previewing an enhanced range of Omics Research Platform Solutions, powered by TransOmics™ 2.0 Informatics.
The new TransOmics 2.0 informatics packages for proteomics and metabolomics/lipidomics, created exclusively for Waters by its strategic business partner Nonlinear Dynamics (Newcastle upon Tyne, UK), are based on extended versions of the Nonlinear Dynamics Progenesis™ LC-MS and CoMet products. The TransOmics 2.0 informatics packages are specifically designed to process and visualize SYNAPT High Definition Mass Spectrometry (HDMS) Omics data, denominated with Collision Cross Section (CCS), from the new Waters SYNAPT G2-Si HDMS mass spectrometer....
Read MoreOrganomation Announces the New Automatic 20 Position N-EVAP Nitrogen EvaporatorJun 14, 2013
Organomation unveils the company’s new Automatic 20 Position Nitrogen Evaporator. This latest addition to the company’s widely successful N-EVAP product line allows for automatic operation to save laboratory technicians time while reducing human error.
Sales Technician Anthony Sacino stated that “The 20 Position Automatic Nitrogen Evaporator was modeled after our most popular product line: the N-EVAP nitrogen evaporators. With their precise needle control and water bath heating technology these instruments have stood the test of time. By reducing human error, the Automatic 20 Position model brings the precision of our nitrogen evaporators to the next level.”...
Waters Corporation (NYSE:WAT) has unveiled the new Waters® SYNAPT® G2-Si Mass Spectrometer at the 61st conference of the American Society of Mass Spectrometry (ASMS).
The company is also previewing its UNIFI® CCS Research Edition and the new TransOmics Version 2.0 informatics products for the new SYNAPT G2-Si mass spectrometer and demonstrating their benefits for a variety of small molecule applications and cutting-edge Omics-focused research. The SYNAPT G2-Si System integrates a third dimension of resolution and separation power into a new suite of untargeted and targeted LC/MS/MS workflows. This powerful new tool gives researchers a means with which to gain a deeper understanding of molecular biology and disease mechanisms, to develop the next generation of healthcare treatments or chemical materials, or to screen food products or environmental samples for contaminants...
For those working at the forefront of polymer development, adding a Malvern Viscotek viscometer detector into gel permeation/size exclusion chromatography (GPC/SEC) set ups can help deliver the enhanced information need to achieve challenging performance specifications.
Studies with evolving commercial polymers, such as polymethylmethacrylate (PMMA) and polylactic acid (PLA), show how the structural information revealed by measuring viscosity parameters enables researchers to intelligently modify polymer chain length and branching to meet precise goals. Malvern Viscotek viscometers can be supplied as part of an integrated triple detector Viscotek GPC/SEC system or as an addition to any existing separation system....
Official launch of an integrated purification system featuring Microsaic’s MiD®
Microsaic Systems plc (AIM: MSYS), welcomes the official launch by Biotage AB (Uppsala, Sweden), a leading global supplier of laboratory equipment, of the Isolera™ Dalton, a fully integrated system for Flash chromatography and mass identification incorporating Microsaic’s novel miniature mass spectrometer – the Microsaic MiD®....Read MoreReproducible Isolation of High Quality RNAJun 5, 2013
INTEGRA has released a new video demonstrating a solid phase extraction (SPE) microplate method for reproducible, high throughput isolation of high-quality DNA-free total RNA.
Large scale gene expression screening projects require reliable high-throughput methods to isolate high quality RNA from a large number of samples. To meet this need, a growing number of commercial 96-well format RNA isolation kits are now available. Typically such kits are compatible with commonly used 96-well plate vacuum manifolds enabling the extraction (isolation) procedure to be accelerated....
Read MoreBiotage Breaks New Ground with Its Fully Integrated Mass Directed Flash SystemJun 4, 2013
Biotage, a leading global supplier of solutions and technology for analytical, medicinal and peptide chemistry, announces the launch of the new Isolera™ Dalton - a fully automated miniaturized mass directed flash purification system.
The new system raises the bar for flash purification by integrating, for the first time, a miniaturized mass detector and an advanced flash chromatography system into one commercially available platform. The mass detector and Isolera™ Spektra flash purification system are seamlessly integrated via the Isolera™ Dalton Nanolink unit, an intelligent sampling device which handles all fluids and synching calculations between the two units.....
Creative Biolabs has developed and commercializes a full range of integrated innovative Bio-fishing services that are based on phage display technology.
With extensive experience in construction of various phage display libraries, including cDNA, peptide and scFv/Fab antibody libraries, Creative Biolabs focuses on developing high specific, high affinity monoclonal antibodies for research, diagnostic and therapeutic use. Creative Biolabs also is professional in screening these libraries against protein, peptide, cells, special surfaces and chemicals.....
Read MoreMerck Millipore to Highlight Latest Advances In Fast HPLC and Separations of Polar Compounds at HPLCMay 30, 2013
Merck Millipore offers a comprehensive portfolio of reliable and reproducible HPLC separation tools even for the most challenging analysis problems in research and development, quality control, environmental, clinical and biochemical analysis.
Join us at HPLC as Merck Millipore highlights its Chromolith® High Resolution HPLC technology, which offers higher efficiency, improved peak shape, and more than two times lower back-pressure than any particulate packed column with the same dimensions. Additionally, the Chromolith® columns have a more than 30% longer lifetime compared with particulate columns....
Read MoreSolid Phase Microextraction (SPME) Specialty Vials and SealsMay 29, 2013
Thicker Lip Vials, Thin Seals
The new Finneran SPME Vials with a thicker lip are ideal for most SPME applications. The thicker lip vial creates a tighter seal on the vial. The Finneran SPME Vials are manufactured from high quality Type 1 borosilicate glass. This new thicker lip vial is available in 10mL and 20mL capacities. To complete the package – JG Finneran offers the 20m gold magnetic seal, 8mm hole with a thin 0.60” PTFE/silicone seal. The thin seal is a perfect choice for SPME applications. The thin seal extends the life of the needle and is available in blue or clear....
Read MoreNot happy with your ion chromatograph? Switch to Metrohm now and save!May 28, 2013
Anyone thinking about exchanging his existing IC system should not wait any longer and switch to Metrohm now.
Less need for expensive consumables, outstanding warranties and integral, fully automated sample preparation will benefit users with lower running costs, more efficiency, and highly dependable Swiss technology - for routine analysis and research alike. Investing in Metrohm ion chromatography means routine analysis with fewer consumables such as syringe filters and filter caps required. Integral, fully automated sample preparation (inline dilution, inline calibration, inline dialysis) saves time and stress....
Spinnovation Analytical B.V. and Pivot Park have entered into an agreement where Spinnovation will supply analytical services at the newly established life sciences park, while gaining access to Pivot Park’s advanced analytical platform.
Pivot Park, located on the former Organon/Schering Plough/MSD research site in Oss, the Netherlands, is a centre for open-innovation, where facilities, instruments and knowledge are made available to the pharmaceutical and biotech companies based on the site. Spinnovation will further support the park’s research and productivity with its portfolio of analytical services specifically designed to address both the needs of the small-molecule pharmaceutical and the biopharmaceutical industries. The agreement will allow Spinnovation to expand and complement its extensive technology platform, thanks to exclusive access to several high-end analytical instruments....
Read MoreAccelerating Isolation of Oils, Fuels and Fats from Natural SourcesMay 20, 2013
Genevac, world leaders in solvent removal technology, has over 20 year’s experience of supplying evaporators for removal of solvents from oil, fat and fuel samples.
Oils, fats and fuels are normally isolated from natural sources using extraction or separation techniques that present the final sample in a solution of organic solvent. Before analysis such samples must be dried or concentrated. Whether extracting and recovering additives, evaluating lipid content of foods, characterising reclaimed cooking oils before reprocessing / conversion to biofuels, or investigating drillling test samples - oils, fuels and fats can often prove difficult to dry without using very high temperatures which may lead to loss of the more volatile fractions within the sample....
Read MoreDebunking Myths about Peak Area Response of Glycoprotein OligosaccharidesMay 20, 2013
Thermo Fisher Scientific has released a technical note (TN) that challenges the common misconception that there is significant variation in high-performance anion-exchange chromatography with pulsed amperometric detection (HPAE-PAD) peak area response of oligosaccharides.
TN 133: HPAE-PAD Peak Area Response of Glycoprotein Oligosaccharides summarizes the peer-reviewed scientific literature concerning this subject. This review concludes that the variation in HPAE-PAD oligosaccharide response with structure is minimal, especially among sets of similar oligosaccharides such as those found on many glycoproteins.....
Merck Millipore highlights its new ZIC®-HILIC technology, a zwitterionic HILIC phase for LC-MS separation of polar compounds.
Merck Millipore offers a comprehensive portfolio of reliable and reproducible LC-MS separation tools even for the most challenging analysis problems in research and development, quality control, environmental, clinical and biochemical analysis.Merck Millipore will host a breakfast seminar on HILIC and analytical chromatography. Presentations include a discussion on how separation selectivity differs between HILIC columns; models will be shown to explain how to select columns....
Thermo Fisher Scientific Inc., the world leader in serving science, introduced the Thermo Scientific™ Dionex™ ERS™ 500 Electrolytically Regenerated Suppressor which replaces the Thermo Scientific™ Dionex™ SRS™ 300 Self Regenerating Suppressor.
The Dionex ERS 500 Suppressor minimizes dispersion to deliver higher resolution separations, especially when coupled with Thermo Scientific™ Dionex™ 4 µm based IC columns. The Dionex ERS 500 suppressor permits improved compatibility with a wider range of detection techniques including MS, ICP, ICP-MS etc. due to its improved backpressure resilience. Additionally, the Dionex ERS 500 suppressor precludes the need for periodic chemical regeneration, allowing for greater ease of use and reproducibility.....
Scientists at the specialised biotech company PharmAbcine are completing formulation and stability studies in a fraction of the time thanks to an Optim 1000 microvolume protein analysis and characterisation instrument from Avacta Analytical.
PharmAbcine was established in the Republic of Korea in 2008 specifically for the development of human monoclonal antibodies into drugs for the treatment of human diseases, including cancer and inflammatory diseases. With one product already undergoing clinical trials for blocking angiogenesis in glioblastomas, and a second monoclonal in development stages, the Company is keen to use high throughput technologies where possible, as Dr Weon Sup Lee, Head of the R&D Center at PharmAbcine, explained....
Read MorePorvair Sciences Announces Summer Show ProgramMay 17, 2013
Porvair Sciences has announced that its latest applications focused microplates and microplate equipment will be exhibited at Forum LABO, European Lab Automation ASMS and HPLC 2013
Visitors to Porvair’s stands at these important events will be able to meet technical specialists, see the company's new UltraVap Mistral microplate evaporator, recently launched range of HPLC sample evaporators and review a wide selection of high quality microplates. Also available will be copies of new mini catalogues for Porvair’s deep well plates, assay plates plus a special catalogue dedicated to serving the North American market....
Read More
New Family of UltraPerformance LC Columns Pushes the Limits of Separation Efficiency and Throughput. Waters Corporation (NYSE:WAT) today introduced CORTECS™ Columns, a new family of 1.6 micron solid-core UltraPerformance LC® Columns that set a new standard in LC column performance. The higher efficiency brought to chromatography with CORTECS Columns allows laboratories to produce greater amounts of information faster with every chromatographic separation...
Large scale gene expression screening projects require reliable high-throughput methods to isolate high quality RNA from a large number of samples. To meet this need, a growing number of commercial 96-well format RNA isolation kits are now available. Typically such kits are compatible with commonly used 96-well plate vacuum manifolds enabling the extraction (isolation) procedure to be accelerated...
The new catalogue contains:
The new TransOmics 2.0 informatics packages for proteomics and metabolomics/lipidomics, created exclusively for Waters by its strategic business partner Nonlinear Dynamics (Newcastle upon Tyne, UK), are based on extended versions of the Nonlinear Dynamics Progenesis™ LC-MS and CoMet products. The TransOmics 2.0 informatics packages are specifically designed to process and visualize SYNAPT High Definition Mass Spectrometry (HDMS) Omics data, denominated with Collision Cross Section (CCS), from the new Waters SYNAPT G2-Si HDMS mass spectrometer....
Sales Technician Anthony Sacino stated that “The 20 Position Automatic Nitrogen Evaporator was modeled after our most popular product line: the N-EVAP nitrogen evaporators. With their precise needle control and water bath heating technology these instruments have stood the test of time. By reducing human error, the Automatic 20 Position model brings the precision of our nitrogen evaporators to the next level.”...
Studies with evolving commercial polymers, such as polymethylmethacrylate (PMMA) and polylactic acid (PLA), show how the structural information revealed by measuring viscosity parameters enables researchers to intelligently modify polymer chain length and branching to meet precise goals. Malvern Viscotek viscometers can be supplied as part of an integrated triple detector Viscotek GPC/SEC system or as an addition to any existing separation system....
Microsaic Systems plc (AIM: MSYS), welcomes the official launch by Biotage AB (Uppsala, Sweden), a leading global supplier of laboratory equipment, of the Isolera™ Dalton, a fully integrated system for Flash chromatography and mass identification incorporating Microsaic’s novel miniature mass spectrometer – the Microsaic MiD®....
Large scale gene expression screening projects require reliable high-throughput methods to isolate high quality RNA from a large number of samples. To meet this need, a growing number of commercial 96-well format RNA isolation kits are now available. Typically such kits are compatible with commonly used 96-well plate vacuum manifolds enabling the extraction (isolation) procedure to be accelerated....
The new system raises the bar for flash purification by integrating, for the first time, a miniaturized mass detector and an advanced flash chromatography system into one commercially available platform. The mass detector and Isolera™ Spektra flash purification system are seamlessly integrated via the Isolera™ Dalton Nanolink unit, an intelligent sampling device which handles all fluids and synching calculations between the two units.....
With extensive experience in construction of various phage display libraries, including cDNA, peptide and scFv/Fab antibody libraries, Creative Biolabs focuses on developing high specific, high affinity monoclonal antibodies for research, diagnostic and therapeutic use. Creative Biolabs also is professional in screening these libraries against protein, peptide, cells, special surfaces and chemicals.....
Join us at HPLC as Merck Millipore highlights its Chromolith® High Resolution HPLC technology, which offers higher efficiency, improved peak shape, and more than two times lower back-pressure than any particulate packed column with the same dimensions. Additionally, the Chromolith® columns have a more than 30% longer lifetime compared with particulate columns....
The new Finneran SPME Vials with a thicker lip are ideal for most SPME applications. The thicker lip vial creates a tighter seal on the vial. The Finneran SPME Vials are manufactured from high quality Type 1 borosilicate glass. This new thicker lip vial is available in 10mL and 20mL capacities. To complete the package – JG Finneran offers the 20m gold magnetic seal, 8mm hole with a thin 0.60” PTFE/silicone seal. The thin seal is a perfect choice for SPME applications. The thin seal extends the life of the needle and is available in blue or clear....
Less need for expensive consumables, outstanding warranties and integral, fully automated sample preparation will benefit users with lower running costs, more efficiency, and highly dependable Swiss technology - for routine analysis and research alike. Investing in Metrohm ion chromatography means routine analysis with fewer consumables such as syringe filters and filter caps required. Integral, fully automated sample preparation (inline dilution, inline calibration, inline dialysis) saves time and stress....
Pivot Park, located on the former Organon/Schering Plough/MSD research site in Oss, the Netherlands, is a centre for open-innovation, where facilities, instruments and knowledge are made available to the pharmaceutical and biotech companies based on the site. Spinnovation will further support the park’s research and productivity with its portfolio of analytical services specifically designed to address both the needs of the small-molecule pharmaceutical and the biopharmaceutical industries. The agreement will allow Spinnovation to expand and complement its extensive technology platform, thanks to exclusive access to several high-end analytical instruments....
Oils, fats and fuels are normally isolated from natural sources using extraction or separation techniques that present the final sample in a solution of organic solvent. Before analysis such samples must be dried or concentrated. Whether extracting and recovering additives, evaluating lipid content of foods, characterising reclaimed cooking oils before reprocessing / conversion to biofuels, or investigating drillling test samples - oils, fuels and fats can often prove difficult to dry without using very high temperatures which may lead to loss of the more volatile fractions within the sample....
TN 133: HPAE-PAD Peak Area Response of Glycoprotein Oligosaccharides summarizes the peer-reviewed scientific literature concerning this subject. This review concludes that the variation in HPAE-PAD oligosaccharide response with structure is minimal, especially among sets of similar oligosaccharides such as those found on many glycoproteins.....
Merck Millipore offers a comprehensive portfolio of reliable and reproducible LC-MS separation tools even for the most challenging analysis problems in research and development, quality control, environmental, clinical and biochemical analysis.Merck Millipore will host a breakfast seminar on HILIC and analytical chromatography. Presentations include a discussion on how separation selectivity differs between HILIC columns; models will be shown to explain how to select columns....
The Dionex ERS 500 Suppressor minimizes dispersion to deliver higher resolution separations, especially when coupled with Thermo Scientific™ Dionex™ 4 µm based IC columns. The Dionex ERS 500 suppressor permits improved compatibility with a wider range of detection techniques including MS, ICP, ICP-MS etc. due to its improved backpressure resilience. Additionally, the Dionex ERS 500 suppressor precludes the need for periodic chemical regeneration, allowing for greater ease of use and reproducibility.....
PharmAbcine was established in the Republic of Korea in 2008 specifically for the development of human monoclonal antibodies into drugs for the treatment of human diseases, including cancer and inflammatory diseases. With one product already undergoing clinical trials for blocking angiogenesis in glioblastomas, and a second monoclonal in development stages, the Company is keen to use high throughput technologies where possible, as Dr Weon Sup Lee, Head of the R&D Center at PharmAbcine, explained....
Visitors to Porvair’s stands at these important events will be able to meet technical specialists, see the company's new UltraVap Mistral microplate evaporator, recently launched range of HPLC sample evaporators and review a wide selection of high quality microplates. Also available will be copies of new mini catalogues for Porvair’s deep well plates, assay plates plus a special catalogue dedicated to serving the North American market....