The Qsep100 DNA Analyzer from Precision Biosystems performs rapid, high sensitivity assays at lower cost per sample compared to similar systems.
Capillary gel electrophoresis technology is recognized as an optimal approach to performing post PCR separation, detection of DNA and RNA fragments and assessing the quality of genomic DNA. The Qsep100 DNA Analyzer, by Precision Biosystems, uses micro-capillary gel electrophoresis combined with fluorescence detection, and is capable of performing 200 assays automatically as quickly as 2 minutes per sample. With costs per sample as low as $0.10 each, Qsep100 is...
Thermo Scientific MAbPac HIC-20 and MAbPac HIC-Butyl Columns Join Lineup
Laboratories characterizing monoclonal antibodies (mAb) now have additional hydrophobic interaction chromatography (HIC) selectivity options, thanks to the expanded family of Thermo Scientific MAbPac HIC HPLC columns. New Thermo Scientific MAbPac HIC-20 and MAbPac HIC-Butyl columns join the company’s line of columns for monoclonal antibody analysis, a response to customer demand for additional selectivity options for...
Advanced Chromatography Technologies Limited have launched new 0.5mm and 1.0mm i.d. microbore ACE UltraCore columns, based on high efficiency, low back pressure solid-core particles with unique Encapsulated Bonding Technology (EBT). These columns have been specifically designed for demanding MS application work and deliver extremely efficient, highly symmetrical peak shapes, which ensures improved MS signal intensity. The SuperC18 phase is...
J. G. Finneran Vial Loaders, manufactured from environmentally-friendly, recycled materials, provide a fast and convenient way of loading vials into all of your 96-well plates.
Finneran Vial Loaders are available with conical or flat bottom polypropylene or glass vials for our patented Multi-TierTM Micro Plate System, or glass conical or tapered bottom vials for many popular 96-Square Deep Well plates. Insert volume sizes range from 350µL glass conical, 6x32mm pulled-point inserts, to volumes of 2.0mL. The inserts are available in clear or amber, with an optional marking spot for easier sample identification....
The MiniVap™ blowdown evaporator from Porvair Sciences takes just minutes to remove volatile organic solvents from your 96-well microplates.
The MiniVap™ is the perfect tool for labs where smaller numbers of individual plates need drying. Incorporating advanced evaporator head technology and an innovative manifold design, which directly injects heated nitrogen into each well of a 96-well microplate simultaneously, the MiniVap enables researchers to remove the traditional laboratory ‘bottleneck’ of solvent evaporation from microplates prior to analysis or reconstitution in buffer...
Merck Millipore, the Life Science business of Merck, today announced the introduction of its AFS® 40E / 80E / 120E and 150E water purification systems.
These new systems have been developed to provide clinical laboratories with an economical and reliable water purification solution for daily water volumes of up to 3000 L. The AFS® 40E / 80E / 120E and 150E systems rely on two powerful technologies to produce water quality meeting Clinical and Laboratory Standards Institute® (CLSI®) Clinical Laboratory Reagent Water standards. State-of-the-art, proven Elix® electrodeionization (EDI) technology ensures constant water quality...
SampleGenie 4 is the latest version of Genevac’s unique technology for direct concentration of large sample volumes into vials, designed for use in the Rocket Synergy Evaporator.
SampleGenie technology enables large sample volumes to be dried directly into vials, eliminating a number of time-consuming sample handling steps and the attendant risk of errors. The latest generation SampleGenie further enhances the exceptional capabilities of the original design. Accommodating sample volumes of up to 250ml, and featuring a new vial adapter insert to suit a range of vials from 12mm to 28mm diameter and up to...
A completely new gel permeation/size exclusion chromatography (GPC/SEC) platform from Malvern Instruments breaks new ground in delivering the high performance, ease of use and productivity demanded in today’s analytical laboratories.
Malvern’s innovative OMNISEC platform integrates highly efficient sample separation via the OMNISEC RESOLVE module and high sensitivity analysis using OMNISEC REVEAL, a fully integrated multi-detector array. The system has applications wherever there is a need for detailed analysis and understanding of natural or synthetic polymers, proteins and macromolecules. GPC/SEC is a two-step analytical process that involves separating a...
Reliable containment of samples is crucial and the integrity, cleanliness and consistency of vials is critical for accurate analysis.
Many analysts think of vials as simple components that do not affect results which is an easy mistake to make…until something goes wrong. Using vials that are not fit for purpose can have a significant impact on the quality of analysis and there are a number of issues to look for in uncertified autosampler vials, including: Non-uniform bottom thickness which can damage needles and cause inconsistent sample draw...
Biologics characterisation from cradle to grave 12th – 13th May 2015 MedImmune Cambridge
Complete characterisation of proteins and peptides is essential across a wide range of industries and applications. The emergence of protein based bio-pharmaceuticals has resulted in increased reliance on the chromatographic and spectrometric techniques used to determine the key quantitative and qualitative attributes of such complex therapeutic entities.
As the importance of steroids in the regulation of bioprocesses has increased so has the demand for fast screening methods for their detection.
HPLC is a highly regarded analytical technique for pharmaceutical applications due to its unrivalled analytical validation characteristics; including accuracy, precision, limit of detection, specificity, linearity and range, and ruggedness. The high throughput demands of quantitative steroid analysis require faster run times and as a result there has been a focus on the development of fast HPLC screening methods to detect steroids...
Researchers at the University of Lethbridge, Alberta, Canada, are using Viscotek multi-detector Gel Permeation/Size Exclusion Chromatography (GPC/SEC) (Malvern Instruments, UK) to analyze performance defining polymer features in the development of novel polymer coatings for metal nanoparticles.
“Multi-detection GPC/SEC helps us to monitor and control reaction conditions to engineer advanced polymer coatings which stabilize nanoparticle suspensions to ease their handling and preserve their industrial value,” said Dr. Farhad Faghihi, Research Associate at the University of Lethbridge. “GPC/SEC is the only technique that we have to determine molecular weight and molecular weight distribution with the speed and accuracy...
New Clarit-E® Choice Stretch Horizontal Electrophoresis Tank
If you need to separate samples with very similar molecular weights, the new Clarit-E® Choice Stretch Electrophoresis Gel Tanks from Alpha Laboratories Ltd. provide the perfect solution. Plus, when you need high throughput, these tanks allow up to 350 samples to be resolved per gel. The extended run lengths of the Choice Stretch Horizontal Tanks allow restriction fragments or other close molecular weight sample bands...
Waters Corporation has announced that its ionKey/MS System™ was ranked among thetop analytical instrument innovations of 2014 by TheAnalytical Scientist magazine.
Introduced at Pittcon 2014, ionKey/MS represents a new approach for achieving exceptional sensitivity, robustness and ease-of-use out of mass spectrometry for applications as far-ranging as bioanalyses, pharmacokinetic studies, and biomarker validation to food safety and environmental analyses. Intended for use with the Waters ACQUITY® UPLC® M-Class System and Waters mass spectrometers including the Xevo® TQ-S Mass Spectrometer and SYNAPT® G2-Si Mass Spectrometer, the Waters® ionKey/MS System physically integrates a UPLC separation into the mass spectrometer....
TSQ Endura LC-MS delivers high sensitivity, extreme uptime
Laboratories performing clinical research and other high throughput LC-MS workflows have access to a new triple quadrupole platform designed for higher uptime than any competitive instrument. The Thermo Scientific Endura triple stage quadrupole mass spectrometer shares much of the advanced technology of the Thermo Scientific TSQ Quantiva MS system developed at the same time to transform the triple quadrupole LC-MS category.....
The globalization of the food chain has meant that the focus on food safety is greater than ever before and as a result, food manufacturers are facing increasingly stringent regulatory requirements.
One area that is receiving a growing amount of attention is mycotoxin intake from contaminated food and feed which causes mycotoxin intoxication. Mycotoxins are secondary fungal metabolites that are typically produced by fungi growing on grains and fruit during shipment or storage. When ingested, mycotoxins may cause acute or chronic disease and it has been shown that repeated exposure to low level mycotoxin ingestion can affect...
iChromatography/Analtech, the only U.S.-based manufacturer of Thin Layer Chromatography Plates, started 2015 with the launch of a new website.
The new site - iChromatography.com - is designed to help visitors find their chromatography product faster and easier as well as discover new developments in the field of separation science. "Since we started more than 50 years ago, we've always been committed to providing not only great products, but the best customer service and information possible to our current and future customers," said Steven C. Miles, General Manager for...
J.G. Finneran Associates designed Limited Volume Inserts with and without Bottom Springs to ensure that autosamplers extract even the smallest sample volumes every time, without damaging injection needles or breaking sample containers.
The inserts preassembled with polymer bottom springs act as shock absorbers to protect sample needles from bottoming out during sample extraction. Inserts without the bottom springs automatically centers in the vial and provides a perfect seal with the septa. The pulled point internal design permits sufficient sample withdrawal and allows chemists the ability to analyze smaller sample volumes in standard size vials.
Read MoreImproved Determination of Key Analytes in Fine Particulate MatterJan 21, 2015
Thermo Fisher Scientific has developed an ion chromatography method with suppressed conductivity detection for sensitive determination of inorganic anions and carboxylic acids (fluoride, acetate, formate, mesylate, chloride, nitrate, succinate, malonate, sulfate, and oxalate) in airborne particulate matter (PM2.5).
Application Note 1107: Determination of Anions and Carboxylic Acids in Urban Fine Particles (PM2.5) demonstrates that this new method can determine more analytes relevant to air contamination than either of the two standard methods currently in use. The determination is performed using a high-pressure ion chromatography system, the Thermo Scientific™ Dionex™ ICS-5000+ Reagent-Free™ HPIC™ system, equipped with a...
Leaks at gas chromatography (GC) column connections are a common source of frustration and wasted time in laboratories.
Time is often spent manually tightening connections between columns using a handheld tool – time which could otherwise be spent analyzing results or running more investigations. Preventing GC leaks has become a priority for researchers looking to save time and money while achieving high quality results. GC column connections leak because capillary column ferrules made of graphite polyimide blends loosen after...
VICI’s Pulsed Discharge helium ionization Detector (PDD) extends the detection capabilities of the popular Agilent 6890 and new 7890 GCs.
The basic operating mode of the PDD can replace many of the detectors currently used by GC manufacturers. Pulsed discharge detector Model D-3-1-HP is designed for plug-and-play installation on Agilent GCs, with models available for the 6890 and 7890. The D-3-1-HP is optimized for trace level work in the helium photoionization mode, and utilizes the electronics and power supply of the host GC. The system includes detector cell, pulser, and...
In collaboration with scientists from the European Union Reference Laboratory for Dioxins and PCBs in Feed and Food, Thermo Fisher Scientific has developed a simple, reliable and robust method for detecting and confirming low levels of dioxins in food and feed samples using a triple quadrupole gas chromatograph-mass spectrometer (GC-MS/MS) system equipped with an autosampler.
Application Note 10406: Validation of GC-MS/MS for Detection and Confirmation of Low-Level Dioxins illustrates the excellent selectivity and sensitivity of this GC-MS/MS System for low levels of dioxins, even in complex matrices. Dioxins are a group of chemically-related compounds, including polychlorinated dibenzodioxins (PCDDs), polychlorinated dibenzofurans (PCDFs), and some dioxin-like polychlorinated biphenyls (PCBs). These compounds are...
Capillary gel electrophoresis technology is recognized as an optimal approach to performing post PCR separation, detection of DNA and RNA fragments and assessing the quality of genomic DNA. The Qsep100 DNA Analyzer, by Precision Biosystems, uses micro-capillary gel electrophoresis combined with fluorescence detection, and is capable of performing 200 assays automatically as quickly as 2 minutes per sample. With costs per sample as low as $0.10 each, Qsep100 is...
Laboratories characterizing monoclonal antibodies (mAb) now have additional hydrophobic interaction chromatography (HIC) selectivity options, thanks to the expanded family of Thermo Scientific MAbPac HIC HPLC columns. New Thermo Scientific MAbPac HIC-20 and MAbPac HIC-Butyl columns join the company’s line of columns for monoclonal antibody analysis, a response to customer demand for additional selectivity options for...
Advanced Chromatography Technologies Limited have launched new 0.5mm and 1.0mm i.d. microbore ACE UltraCore columns, based on high efficiency, low back pressure solid-core particles with unique Encapsulated Bonding Technology (EBT). These columns have been specifically designed for demanding MS application work and deliver extremely efficient, highly symmetrical peak shapes, which ensures improved MS signal intensity. The SuperC18 phase is...
Finneran Vial Loaders are available with conical or flat bottom polypropylene or glass vials for our patented Multi-TierTM Micro Plate System, or glass conical or tapered bottom vials for many popular 96-Square Deep Well plates. Insert volume sizes range from 350µL glass conical, 6x32mm pulled-point inserts, to volumes of 2.0mL. The inserts are available in clear or amber, with an optional marking spot for easier sample identification....
The MiniVap™ is the perfect tool for labs where smaller numbers of individual plates need drying. Incorporating advanced evaporator head technology and an innovative manifold design, which directly injects heated nitrogen into each well of a 96-well microplate simultaneously, the MiniVap enables researchers to remove the traditional laboratory ‘bottleneck’ of solvent evaporation from microplates prior to analysis or reconstitution in buffer...
These new systems have been developed to provide clinical laboratories with an economical and reliable water purification solution for daily water volumes of up to 3000 L. The AFS® 40E / 80E / 120E and 150E systems rely on two powerful technologies to produce water quality meeting Clinical and Laboratory Standards Institute® (CLSI®) Clinical Laboratory Reagent Water standards. State-of-the-art, proven Elix® electrodeionization (EDI) technology ensures constant water quality...
SampleGenie technology enables large sample volumes to be dried directly into vials, eliminating a number of time-consuming sample handling steps and the attendant risk of errors. The latest generation SampleGenie further enhances the exceptional capabilities of the original design. Accommodating sample volumes of up to 250ml, and featuring a new vial adapter insert to suit a range of vials from 12mm to 28mm diameter and up to...
Malvern’s innovative OMNISEC platform integrates highly efficient sample separation via the OMNISEC RESOLVE module and high sensitivity analysis using OMNISEC REVEAL, a fully integrated multi-detector array. The system has applications wherever there is a need for detailed analysis and understanding of natural or synthetic polymers, proteins and macromolecules. GPC/SEC is a two-step analytical process that involves separating a...
Many analysts think of vials as simple components that do not affect results which is an easy mistake to make…until something goes wrong. Using vials that are not fit for purpose can have a significant impact on the quality of analysis and there are a number of issues to look for in uncertified autosampler vials, including: Non-uniform bottom thickness which can damage needles and cause inconsistent sample draw...
Complete characterisation of proteins and peptides is essential across a wide range of industries and applications. The emergence of protein based bio-pharmaceuticals has resulted in increased reliance on the chromatographic and spectrometric techniques used to determine the key quantitative and qualitative attributes of such complex therapeutic entities.
HPLC is a highly regarded analytical technique for pharmaceutical applications due to its unrivalled analytical validation characteristics; including accuracy, precision, limit of detection, specificity, linearity and range, and ruggedness. The high throughput demands of quantitative steroid analysis require faster run times and as a result there has been a focus on the development of fast HPLC screening methods to detect steroids...
“Multi-detection GPC/SEC helps us to monitor and control reaction conditions to engineer advanced polymer coatings which stabilize nanoparticle suspensions to ease their handling and preserve their industrial value,” said Dr. Farhad Faghihi, Research Associate at the University of Lethbridge. “GPC/SEC is the only technique that we have to determine molecular weight and molecular weight distribution with the speed and accuracy...
If you need to separate samples with very similar molecular weights, the new Clarit-E® Choice Stretch Electrophoresis Gel Tanks from Alpha Laboratories Ltd. provide the perfect solution. Plus, when you need high throughput, these tanks allow up to 350 samples to be resolved per gel. The extended run lengths of the Choice Stretch Horizontal Tanks allow restriction fragments or other close molecular weight sample bands...
Introduced at Pittcon 2014, ionKey/MS represents a new approach for achieving exceptional sensitivity, robustness and ease-of-use out of mass spectrometry for applications as far-ranging as bioanalyses, pharmacokinetic studies, and biomarker validation to food safety and environmental analyses. Intended for use with the Waters ACQUITY® UPLC® M-Class System and Waters mass spectrometers including the Xevo® TQ-S Mass Spectrometer and SYNAPT® G2-Si Mass Spectrometer, the Waters® ionKey/MS System physically integrates a UPLC separation into the mass spectrometer....
Laboratories performing clinical research and other high throughput LC-MS workflows have access to a new triple quadrupole platform designed for higher uptime than any competitive instrument. The Thermo Scientific Endura triple stage quadrupole mass spectrometer shares much of the advanced technology of the Thermo Scientific TSQ Quantiva MS system developed at the same time to transform the triple quadrupole LC-MS category.....
The new site - iChromatography.com - is designed to help visitors find their chromatography product faster and easier as well as discover new developments in the field of separation science. "Since we started more than 50 years ago, we've always been committed to providing not only great products, but the best customer service and information possible to our current and future customers," said Steven C. Miles, General Manager for...
The inserts preassembled with polymer bottom springs act as shock absorbers to protect sample needles from bottoming out during sample extraction. Inserts without the bottom springs automatically centers in the vial and provides a perfect seal with the septa. The pulled point internal design permits sufficient sample withdrawal and allows chemists the ability to analyze smaller sample volumes in standard size vials.
Application Note 1107: Determination of Anions and Carboxylic Acids in Urban Fine Particles (PM2.5) demonstrates that this new method can determine more analytes relevant to air contamination than either of the two standard methods currently in use. The determination is performed using a high-pressure ion chromatography system, the Thermo Scientific™ Dionex™ ICS-5000+ Reagent-Free™ HPIC™ system, equipped with a...
The basic operating mode of the PDD can replace many of the detectors currently used by GC manufacturers. Pulsed discharge detector Model D-3-1-HP is designed for plug-and-play installation on Agilent GCs, with models available for the 6890 and 7890. The D-3-1-HP is optimized for trace level work in the helium photoionization mode, and utilizes the electronics and power supply of the host GC. The system includes detector cell, pulser, and...