Researchers in the Department of Microbiology and Immunology at the University of Otago, New Zealand, are focused on understanding the mechanisms and clinical consequences of drug resistant viruses, as well as performing antiviral drug discovery. The group is using INTEGRA’s ASSIST PLUS pipetting robot and VOYAGER adjustable tip spacing pipettes to streamline a number of its workflows....
Agilent Technologies Inc. has announced it will expand its state-of-the-art production facility in Frederick, Colorado, that develops and manufactures “oligos,” which are short DNA and RNA molecules used to create nucleic acid-based therapeutics. Oligos hold the potential to be used in developing treatments for cancer, COVID-19, cardiovascular disease, rare and infectious diseases, and other conditions....
While it is well recognised that the risk of a severe COVID-19 infection is linked to certain long-term health conditions, little is known, so far, about the effects of multimorbidity and polypharmacy (taking multiple medications) on the risk of a serious coronavirus infection. Now, a new study led by the University of Glasgow and published in PLOS ONE, is the first to link both multimorbidity and polypharmacy with the risk of having a positive COVID-19 test....
(U)HPLC analysis of original composition of cannabis plant material is necessary for such purposes as phenotype determination and quality control of medical cannabis used for therapeutic treatment. For fast and secure results YMC developed robust (U)HPLC methods for RP and chiral LC. Also, challenging distinction between cannabigerol (CBG) andcannabidiol (CBD) are easily achieved....
A double door, or pass-through autoclave provides a pathway for objects into a room. Anything entering or leaving via this portal is sterilised. This is especially useful when either trying to keep biologically hazardous materials inside or out of a room. However, not all pass-through autoclaves are equal. Let’s have a look at some of the features you should consider when purchasing a pass-through autoclave...
Carterra® Inc., the world leader in high-throughput antibody screening and characterization, has announced the availability of a highly accurate assay for simultaneously measuring the concentration and binding of IgG, IgM, and IgA antibodies to the Receptor Binding Domain (RBD) of SARS-CoV-2. Carterra’s new label-free assay provides, for the first time, detailed resolution of the immune response of patients recovering from COVID-19 in a single assay...
Edinburgh-based biotech company Ingenza Ltd. has made a significant breakthrough in the race to develop and manufacture a cost-effective vaccine against SARS-CoV-2, the virus responsible for the current COVID-19 pandemic. Ingenza has been working closely with researchers at Oxford University and the UK CPI, Wilton, since the start of the outbreak, and the collaboration is continuing to make excellent progress...
An international team of scientists, led by the University of Glasgow, has announced findings that could pave the way to a new treatment for asthma and chronic obstructive pulmonary disease (COPD). The breakthrough findings, published in Science Translational Medicine, identify a new class of drugs that reverse the symptoms of asthma in animal models....
More than 305,000 high-resolution, multi-channel COVID-19 cellular images captured in less than four weeks with Molecular Devices ImageXpress® Micro Confocal High-Content Imaging System are now available to the scientific community. With the COVID-19 pandemic impacting millions around the globe, researchers are racing to develop a vaccine or drug treatment. In an effort to better understand the cellular responses to COVID-19, the digital biology company Recursion has publicly released the world’s largest imaging dataset....
Autoscribe Informatics has just released a new case study in conjunction with Swiss Precision Diagnostics (SPD) who have replaced their legacy Laboratory Information Management System (LIMS) with Matrix Gemini. The new LIMS integrates data from volunteer sample collection, laboratory testing and a clinical biobank to provide integrated data management across their organization....
Intravacc and the Celonic Group has announced that they have signed a research agreement to further design, develop and produce a Covid-19 vaccine based on an immunogenic Spike (S) protein of SARS-CoV-2 combined with Intravacc’s prorietary Outer Membrane Vesicle (OMV) technology. In the beginning of March this year Intravacc started working on the development of four candidate coronavirus vaccines...
This year, in addition to the academic year course ‘Honors Computational Medicinal Chemistry’, 80 rising juniors and seniors will embark upon a special summer short-course entitled ‘Computing COVID-19’, utilizing StarDrop in conjunction with other bioinformatics tools. Optibrium’s lead product, StarDrop, is a comprehensive suite of integrated software...
Avacta Group plc, the developer of Affimer® biotherapeutics and reagents, is pleased to announce that it has entered into a collaboration with the Liverpool School of Tropical Medicine (“LSTM”) to clinically validate the rapid, saliva-based coronavirus antigen test that Avacta is developing with Cytiva. LSTM has been at the forefront of research into infectious, debilitating and disabling diseases since 1898....
Further easing of import restrictions by the Government will provide faster access to patients prescribed cannabis-based medicines — and is the removal of yet another barrier in a market expected to grow in the coming years. Here, Katie Gray, marketing manager at Lab Innovations 2020, the largest laboratory event in the UK, looks at why labs will need to become more adaptable....
Researchers are turning to INTEGRA Biosciences VIAFLO 96/384 handheld electronic pipette for rapid and precise filling of specialized 3D cell culture plates, to increase throughput and meet the demands of high volume drug discovery programs. Specialized 3D cell culture plates, such as Corning® Elplasia® microplates, enable highly reproducible growth of uniform 3D cultures for downstream applications...
Advanced Biological Laboratories (ABL) announced the CE-IVD marking of its DeepChek®-HIV assays, is now available for in-vitro diagnostics. Intended to be used on HIV-1 Group M viruses from patients diagnosed with HIV infection, the assays deliver standardized, open and flexible solution suited to clinical settings performing sequencing through Capillary Electrophoresis and Next Generation Sequencing (NGS) systems...
Absolute Antibody Ltd., an industry-leading provider of recombinant antibody products and services, has announced a partnership with University of Zurich to offer synthetic nanobodies against the receptor binding domain (RBD) of SARS-CoV-2, the coronavirus that causes COVID-19. Under the partnership, the original nanobodies and newly engineered formats are now available to the global research community for use as serological controls and in COVID-19 therapeutic development....
Contract research organization (CRO) Radix BioSolutions is using the entire span of INTEGRA pipetting products to streamline its workflows and increase reproducibility. Dr Kerry Oliver, President and CSO of Radix, explained: “Our services cover everything from quantifying biomarkers and reagent labeling services to the development and production of multiplexed assays, and we use INTEGRA products across our workflow.”...
Tackling a pandemic is a massive effort that calls people from disciplines far and wide. Politicians, public figures and, of course, medical staff are all deeply involved in the response. Hidden just behind the front lines, however, are laboratories that are working to bring these unprecedented times to an end. Here, Lab Innovations 2020 hears from Anthony Cooke, CEO of Cambridge Clinical Laboratories...
A team of scientists at the University of Glasgow has identified a cat in the UK that was infected with SARS-CoV-2, the virus that causes COVID-19. Researchers from the MRC-University of Glasgow Centre for Virus Research (CVR) in partnership with the Veterinary Diagnostic Service (VDS) of the University’s School of Veterinary Medicine made the discovery as part of their joint research programme...
Merck, a leading science and technology company, opened its M Lab™ Collaboration Center in Shanghai, the company’s largest of nine centers worldwide. “With the booming pharmaceutical industry in Asia and greater emphasis on novel drug therapies, we see an increase in R&D on leading-edge treatments including cell and gene therapies in China,” said Udit Batra, member of the Merck Executive Board and CEO, Life Science....
An article in the June 18, 2020 edition of the journal Nature Biotechnology details a timely project at the University of California, Berkeley: how to create a CLIA-certified COVID-19 testing lab from a research lab, in only three weeks. Read more about how we radically reduced a 6-12 month timeline....