Analysis of thousands of NHS records has uncovered a link between an increased dosage of insulin in the treatment of type 2 diabetes and a heightened risk of death in patients.
In a report published today in the journal of Diabetes, Obesity and Metabolism, researchers from Cardiff University were also able to show a correlation between patients treated with a higher dosage of insulin and a raised risk of cancer development, heart attacks and stroke. Researchers identified these trends by scrutinizing the medical history of 6,484 patients with type 2 diabetes extracted from the UK Clinical Practice Research Datalink (CPRD). Patients were on average aged 64 at the beginning of the study in 2000, and were followed for an average of...
FMI’s NEW Video unlocks the secret to precision valveless piston pumping through a series of 3D pump animations and HD graphic illustrations.
This high definition streaming video also contains supporting technical descriptions, as well as specific advantages CeramPump® technology offers. For over 55 years, critical medical, analytical, laboratory, industrial, and OEM instrumentation applications requiring precision metering and dosing have relied on Fluid Metering, Inc.’s (FMI) CeramPump® valveless piston pumping technology. The CeramPump’s® innovative pumping...
The Indian pharmaceutical market accounts for more than 10% of global drug production.
It is one of the country’s biggest employers, with more than 340,000 Indian employees dedicated to an industry that is worth in excess of $22 billion, and pharmaceutical exports of some $14.7 billion in 2013, with 55% heading to highly regulated Western markets. Zydus Cadila, a fully integrated, global healthcare provider and the fifth largest pharmaceutical company in India, recently decided to improve its solid oral dosage form production...
ZEISS announces the sublicensing of Lattice light sheet microscopy, also called Bessel beam plane illumination microscopy, to Intelligent Imaging Innovations (3i).
ZEISS and the Howard Hughes Medical Institute’s Janelia Research Campus had signed an exclusive license agreement for the commercialization of Lattice light sheet microscopy earlier this year. By granting the exclusive sublicense to 3i, ZEISS is contributing to making Lattice light sheet microscopy available to scientists and early adopters in a timely manner. 3i will sell and support the development system based on Dr. Eric Betzig’s original design...
The microbiome is a new concept that will be heard of increasingly in the next few years.
It relates to the bacteria in our gut which outnumber our human cells 10-1. It turns out that not only they are the majority, but they are in control as well! A packed meeting, the third in the Core Exploring the Science of Digestion series, heard how the microbiome may influence mood, personality and possibly intelligence as well as playing a key role in diseases of the gastrointestinal tract such as C. difficile, Crohn’s disease and...
Lab M is seeing demand grow quickly for the company’s recently launched µPrep™ Half Fraser Broth ISO (+FAC), a complete primary enrichment broth designed for use in the isolation of Listeria spp. from foodstuffs.
Media in Lab M’s µPrep™ range are supplied ready-to-reconstitute in 20 litre bags. They are designed primarily for high throughput laboratories where speed, convenience, reliability and cost-effectiveness are high priorities. “Since we launched µPrep™ Half Fraser Broth ISO (+FAC) in July 2014, customers have been very clear that simple reconstitution with no mess and no autoclaving is a significant factor in their choice of media format...
A Morphologi G3-ID particle characterization system from Malvern Instruments is opening cutting-edge research opportunities in environmental science at the School of Science, Environment and Engineering, Southern Cross University (SCU), in Australia.
The Morphologi G3-ID, which is sold and supported in Australia by ATA Scientific, combines automated particle imaging with Raman spectroscopy to deliver particle size, morphology and chemical identification of particles within a dispersion. The technique is helping users to better understand the composition and behavior of natural particles within the environment and is generating substantial cost and efficiency savings in areas that...
In collaboration with scientists from the European Union Reference Laboratory for Dioxins and PCBs in Feed and Food, Thermo Fisher Scientific has developed a simple, reliable and robust method for detecting and confirming low levels of dioxins in food and feed samples using a triple quadrupole gas chromatograph-mass spectrometer (GC-MS/MS) system equipped with an autosampler.
Application Note 10406: Validation of GC-MS/MS for Detection and Confirmation of Low-Level Dioxins illustrates the excellent selectivity and sensitivity of this GC-MS/MS System for low levels of dioxins, even in complex matrices. Dioxins are a group of chemically-related compounds, including polychlorinated dibenzodioxins (PCDDs), polychlorinated dibenzofurans (PCDFs), and some dioxin-like polychlorinated biphenyls (PCBs). These compounds are...
Malvern Instruments has released new guidance on using automated image analysis to detect and quantify agglomerates.
The ability of uncontrolled agglomeration to substantially impact the performance and value of powder products makes efficient agglomerate detection vital across a number of industries. ‘Identification of agglomerates using automated image analysis’ presents practical strategies for efficiently and robustly differentiating agglomerates from primary particles, to support product development, QC and process troubleshooting....
Reducing infection transmission risk on a paediatric high dependency unit was just one of the topics under discussion at Lyon, France on the first day of the Healthcare Infection Society Conference 2014.
A study showing how the Bioquell Pod has benefited the Alder Hey Children’s NHS Foundation Trust was presented to leading healthcare professionals. The Bioquell Pod is an infection control enclosure that has been designed to limit the spread of pathogens in ward environments and can be used to convert units into single occupancy rooms. It facilitates infection control management by segregating patients while offering easy...
These high-profile experts will help with the quick and safe launch of the preclinical development program for a new class of antibiotics
Nosopharm, a company devoted to the research and development of new anti-infective drugs, today announces the appointment of four international experts to its scientific advisory board. These appointments reflect a new phase of development for its novel antibiotic class called Odilorhabdins. The members of the scientific advisory board will aid in the selection of a clinical candidate. This will be the first-generation Odilorhabdin derived from the...
The new AdvanDx mecA XpressFISH assay, exclusively available in the UK from Alpha Laboratories, is the first and only molecular assay that detects the active resistance gene (mecA) from positive Staphylococcus aureus blood cultures.
It provides results one to three days sooner than conventional methods, allowing for early and appropriate therapy for patients with methicillin-resistant S.aureus (MRSA) and methicillin-sensitive S.aureus (MSSA) infections. Differentiation also enables de-escalation of vancomycin treatment for patients with MSSA infections. Methicillin-resistant Staphylococcus aureus (MRSA) is one of the most common antimicrobial resistant pathogens and can...
JPK Instruments, a world-leading manufacturer of nanoanalytic instrumentation for research in life sciences and soft matter, reports on the use of AFM and the CellHesion® module to study plant cell wall biology in the School of Chemical Engineering at the University of Queensland.
The Australian Research Council Centre of Excellence in Plant Cell Walls is a collaborative project involving the Universities of Adelaide, Melbourne and Queensland in partnership with South Australia State Government and seven international institutions. Their aim is to advance fundamental scientific understanding of plant cell wall biology. Cell wall composition determines the quality of most plant-based products used in modern human societies...
Syngene, a world-leading manufacturer of sensitive image analysis solutions, is proud to announce its G:BOX Chemi XRQ is being used by scientists at a well-respected European University to accurately detect proteins in metabolic disorders including diabetes.
Researchers at the major university are using a G:BOX Chemi XRQ multi-task imager to precisely analyse agarose gels of mouse and rabbit DNA stained with the safe fluorescent dye SybrSafe®. They are also utilising the G:BOX Chemi XRQ to easily image both large and small SDS-PAGE gels and chemiluminescent Western blots of proteins. This is allowing scientists at the university to accurately detect proteins and is contributing to identifying potential therapeutic targets in...
LaVison BioTec, developers of advanced microscopy solutions for the life sciences, report on the research of Dr Peter Friedl and his imaging of cancer growth using intravital microscopy.
Peter Friedl holds the chair for Microscopical Imaging of the Cell at the St. Radboud University Nijmegen Medical Centre, University of Nijmegen, The Netherlands. He also holds a 20% joint-appointment as head of the imaging section at the David H. Koch Center, Department of Genitourinary Oncology, MD Anderson Cancer Center, Houston, TX, USA. His research work focuses on imaging cancer growth, metastasis and therapy response in the...
Fast, efficient and non-destructive towards precious samples, light microscopy plays a vital role throughout forensic science operations, especially in Dr Kevin Farrugia’s laboratory.
Employing the Olympus DSX100 Opto-digital system, Dr Farrugia’s research at the University of Abertay (Dundee, Scotland) has been greatly enhanced through a combination of digital and optical technologies. Such advanced light microscopy has yielded greater insights into a variety of forensic samples, revealing fingerprints on metal, pen marks on paper and characterising unique designs on seized illicit tablets...
An automated dynamic light scattering system from Malvern Instruments has become established as an essential part of the analytical toolkit used by SARomics Biostructures AB, a leading provider of protein 3D structure determination and structure-based drug design services.
The Zetasizer APS automated plate sampling system is supporting the systematic study of the aggregation behavior of proteins, a fundamental component of the services provided by SARomics Biostructures. The company, which is based in Lund, Sweden within the biotech cluster of the Medicon Valley, is a research-intensive organization with clients around the world.
FLIR Systems, the global leader in thermal imaging, has announced its 15th Annual InfraMation Conference to be held May 12-15 2015 in Nashville, Tenneesee (USA).
The InfraMation Conference is widely acknowledged as a leading international event for attendees to learn about the latest thermal imaging techniques and applications, and network with many hundreds of industry colleagues. This conference is for thermographers, regardless of which camera system they might use, or those just interested in the latest new applications of the technology. InfraMation 2015 will feature leading industry...
At the renowned Midsummer House Restaurant in Cambridge, UK the chefs have been experimenting with centrifugal evaporation, using the Genevac Rocket evaporator.
Using the centrifugal evaporation technique, Midsummer House chefs are taking large volumes of liquid and concentrating them down. These concentrates can be used to increase the depth of flavour of sauces or stocks or to create unique flavour combinations. Centrifugal evaporation is predominantly used in analytical laboratories, where the quality of the final product is absolutely vital – just as it is in the kitchen. At Midsummer House, Head Chef Daniel Clifford’s cooking has a...
Thermo Fisher Scientific has developed two robust methods to identify uronic acids in acid-hydrolyzed wood samples, with each method using a different specialized anion-exchange column as demonstrated in Application Note 1091: Determination of Uronic Acids and Wood Sugars in Wood-Based Hydrolysates.
Method 1 is a single high-performance anion-exchange chromatography with pulsed amperometric detection method that uses a mono- and disaccharide column, the Thermo Scientific™ Dionex™ CarboPac™ PA20 column, for wood sugars and uronic acids. Method 2 is a faster method that uses an oligosaccharide column...
With Ebola cases reaching the USA, the public has become more conscious about infectious diseases and infection control.
Hospitals face the challenge of infection prevention on a daily basis. Whilst some are in the process of setting up Ebola preparedness protocols, some like the Rome Memorial Hospital, New York, are already fully equipped to handle a case should it present itself. As broadcasted in two features on WKTV News and CNY, Rome Memorial already uses Bioquell’s hydrogen peroxide vapour (HPV) technology to fight more common infections...
LGC has announced that its ISO17025 accreditation from the United Kingdom Accreditation Service (UKAS) has been further extended to include steroids in its Occupational Drug Testing (ODT) suite of tests.
LGC is an international life sciences measurement and testing company with a specialism in testing for drugs of abuse. The ODT team was awarded ISO17025 accreditation for analysis of oral fluid in May 2014. Simon Hudson, Technical Director for the laboratory and managed services division of LGC commented, “We are proud to extend our ISO17025 accreditation for steroids in human urine samples. Having this further extension acknowledged by an...
This high definition streaming video also contains supporting technical descriptions, as well as specific advantages CeramPump® technology offers. For over 55 years, critical medical, analytical, laboratory, industrial, and OEM instrumentation applications requiring precision metering and dosing have relied on Fluid Metering, Inc.’s (FMI) CeramPump® valveless piston pumping technology. The CeramPump’s® innovative pumping...
It is one of the country’s biggest employers, with more than 340,000 Indian employees dedicated to an industry that is worth in excess of $22 billion, and pharmaceutical exports of some $14.7 billion in 2013, with 55% heading to highly regulated Western markets. Zydus Cadila, a fully integrated, global healthcare provider and the fifth largest pharmaceutical company in India, recently decided to improve its solid oral dosage form production...
ZEISS and the Howard Hughes Medical Institute’s Janelia Research Campus had signed an exclusive license agreement for the commercialization of Lattice light sheet microscopy earlier this year. By granting the exclusive sublicense to 3i, ZEISS is contributing to making Lattice light sheet microscopy available to scientists and early adopters in a timely manner. 3i will sell and support the development system based on Dr. Eric Betzig’s original design...
It relates to the bacteria in our gut which outnumber our human cells 10-1. It turns out that not only they are the majority, but they are in control as well! A packed meeting, the third in the Core Exploring the Science of Digestion series, heard how the microbiome may influence mood, personality and possibly intelligence as well as playing a key role in diseases of the gastrointestinal tract such as C. difficile, Crohn’s disease and...
Media in Lab M’s µPrep™ range are supplied ready-to-reconstitute in 20 litre bags. They are designed primarily for high throughput laboratories where speed, convenience, reliability and cost-effectiveness are high priorities. “Since we launched µPrep™ Half Fraser Broth ISO (+FAC) in July 2014, customers have been very clear that simple reconstitution with no mess and no autoclaving is a significant factor in their choice of media format...
The Morphologi G3-ID, which is sold and supported in Australia by ATA Scientific, combines automated particle imaging with Raman spectroscopy to deliver particle size, morphology and chemical identification of particles within a dispersion. The technique is helping users to better understand the composition and behavior of natural particles within the environment and is generating substantial cost and efficiency savings in areas that...
Application Note 10406: Validation of GC-MS/MS for Detection and Confirmation of Low-Level Dioxins illustrates the excellent selectivity and sensitivity of this GC-MS/MS System for low levels of dioxins, even in complex matrices. Dioxins are a group of chemically-related compounds, including polychlorinated dibenzodioxins (PCDDs), polychlorinated dibenzofurans (PCDFs), and some dioxin-like polychlorinated biphenyls (PCBs). These compounds are...
The ability of uncontrolled agglomeration to substantially impact the performance and value of powder products makes efficient agglomerate detection vital across a number of industries. ‘Identification of agglomerates using automated image analysis’ presents practical strategies for efficiently and robustly differentiating agglomerates from primary particles, to support product development, QC and process troubleshooting....
A study showing how the Bioquell Pod has benefited the Alder Hey Children’s NHS Foundation Trust was presented to leading healthcare professionals. The Bioquell Pod is an infection control enclosure that has been designed to limit the spread of pathogens in ward environments and can be used to convert units into single occupancy rooms. It facilitates infection control management by segregating patients while offering easy...
Nosopharm, a company devoted to the research and development of new anti-infective drugs, today announces the appointment of four international experts to its scientific advisory board. These appointments reflect a new phase of development for its novel antibiotic class called Odilorhabdins. The members of the scientific advisory board will aid in the selection of a clinical candidate. This will be the first-generation Odilorhabdin derived from the...
It provides results one to three days sooner than conventional methods, allowing for early and appropriate therapy for patients with methicillin-resistant S.aureus (MRSA) and methicillin-sensitive S.aureus (MSSA) infections. Differentiation also enables de-escalation of vancomycin treatment for patients with MSSA infections. Methicillin-resistant Staphylococcus aureus (MRSA) is one of the most common antimicrobial resistant pathogens and can...
The Australian Research Council Centre of Excellence in Plant Cell Walls is a collaborative project involving the Universities of Adelaide, Melbourne and Queensland in partnership with South Australia State Government and seven international institutions. Their aim is to advance fundamental scientific understanding of plant cell wall biology. Cell wall composition determines the quality of most plant-based products used in modern human societies...
Researchers at the major university are using a G:BOX Chemi XRQ multi-task imager to precisely analyse agarose gels of mouse and rabbit DNA stained with the safe fluorescent dye SybrSafe®. They are also utilising the G:BOX Chemi XRQ to easily image both large and small SDS-PAGE gels and chemiluminescent Western blots of proteins. This is allowing scientists at the university to accurately detect proteins and is contributing to identifying potential therapeutic targets in...
Peter Friedl holds the chair for Microscopical Imaging of the Cell at the St. Radboud University Nijmegen Medical Centre, University of Nijmegen, The Netherlands. He also holds a 20% joint-appointment as head of the imaging section at the David H. Koch Center, Department of Genitourinary Oncology, MD Anderson Cancer Center, Houston, TX, USA. His research work focuses on imaging cancer growth, metastasis and therapy response in the...
Employing the Olympus DSX100 Opto-digital system, Dr Farrugia’s research at the University of Abertay (Dundee, Scotland) has been greatly enhanced through a combination of digital and optical technologies. Such advanced light microscopy has yielded greater insights into a variety of forensic samples, revealing fingerprints on metal, pen marks on paper and characterising unique designs on seized illicit tablets... 
The Zetasizer APS automated plate sampling system is supporting the systematic study of the aggregation behavior of proteins, a fundamental component of the services provided by SARomics Biostructures. The company, which is based in Lund, Sweden within the biotech cluster of the Medicon Valley, is a research-intensive organization with clients around the world.
The InfraMation Conference is widely acknowledged as a leading international event for attendees to learn about the latest thermal imaging techniques and applications, and network with many hundreds of industry colleagues. This conference is for thermographers, regardless of which camera system they might use, or those just interested in the latest new applications of the technology. InfraMation 2015 will feature leading industry...
Using the centrifugal evaporation technique, Midsummer House chefs are taking large volumes of liquid and concentrating them down. These concentrates can be used to increase the depth of flavour of sauces or stocks or to create unique flavour combinations. Centrifugal evaporation is predominantly used in analytical laboratories, where the quality of the final product is absolutely vital – just as it is in the kitchen. At Midsummer House, Head Chef Daniel Clifford’s cooking has a...
LGC is an international life sciences measurement and testing company with a specialism in testing for drugs of abuse. The ODT team was awarded ISO17025 accreditation for analysis of oral fluid in May 2014. Simon Hudson, Technical Director for the laboratory and managed services division of LGC commented, “We are proud to extend our ISO17025 accreditation for steroids in human urine samples. Having this further extension acknowledged by an...