Magritek, a leading provider of compact NMR and MRI instruments, reports on the use of their Spinsolve Benchtop NMR spectrometer in the teaching of practical chemistry to students at Bloomfield College in New Jersey.
Dr Maria Vogt is Professor of Chemistry at Bloomfield College, an undergraduate college in New Jersey. She teaches lectures and runs labs in Organic Chemistry and Biochemistry. Having had a prior research career and publishing more than 45 papers, Dr Vogt now devotes her efforts to prepare students for the "real world" by exposing them to as many hands-on and instrumental skills as possible prior to...
JPK Instruments, a world-leading manufacturer of nanoanalytic instrumentation for research in life sciences and soft matter, reports on the research into the interaction of bacteria with microstructured surfaces in the Department of Physics at the University of Kaiserslautern in Germany.
Dr Christine Müller-Renno is a member of the Ziegler Group in the Physics Department at the University of Kaiserslautern in Germany. The main topics of their research are in nano- and microelectronics, as well as in medical engineering and fluid analysis. Other topics include catalysts and stain-resistant coatings by the use of nanomaterials. The Group uses the JPK NanoWizard® AFM to study the...
How Providing Comprehensive Data Can Accelerate Drug Development
Sartorius Stedim BioOutsource today announced that its scientific experts will be presenting a live webinar about optimizing biosimilar analysis on Thursday, June 2, at 3 pm BST, 10 am EDT. The webinar is essential listening for researchers who want to understand how to select optimal clones and processes to accelerate development of their biosimilars. During the one-hour webinar, Dr. Martin De Cecco, and...
BioTek Instruments is pleased to announce its collaboration with Merck on an integrated solution for long-term live cell experiments and dynamic time-lapse analyses, including automated cell perfusion and imaging.
The solution leverages each company’s respective expertise, and consists of BioTek’s new Lionheart™ FX Automated Live Cell Imager and Merck’s new CellASIC® ONIX2 Microfluidic System. This collaborative solution was introduced at the American Association of Cancer Research (AACR) Annual Meeting recently held in New Orleans, LA. The Lionheart FX Automated Live Cell Imager is optimized for live cell...
ARGENX announced today having signed a major deal with AbbVie in the field of immuno-oncology.
This deal is the result of a highly productive collaboration between ARGENX, a biotech company, and the teams of Professors Pierre Coulie and Sophie Lucas of the Université catholique de Louvain (UCL), who are recognized worldwide as leaders in the field of immuno-oncology. This collaboration has resulted in an innovative therapeutic approach to stimulate the immune system of cancer patients...
The Division of Cell and Developmental Biology, part of the University of Dundee’s School of Life Sciences, is taking advantage of Anachem’s recently launched Rainin TerraRack™ pipette tip racks to minimize storage and waste disposal requirements.
Ian Newton, Scientific Officer in the Näthke lab, explained: “Our laboratory is focused on adenomatous polyposis coli (APC), a multi-functional protein which has a role in a variety of basic cellular processes, including cell migration, cell adhesion, and proliferation. Mutations in APC are closely linked with both inherited and sporadic colon cancer, and we use a variety of techniques to investigate the various protein interactions of APC in vivo....
Cepheid Highlights Role of Diagnostics as Valuable Tool in Growing Fight Against Antibiotic Resistance
Cepheid (Nasdaq: CPHD) have announced the launch of its 'Diagnostics First' campaign to raise awareness for the use of accurate and fast diagnostic tests to inform optimal treatment decisions and avoid over-prescription of the world's limited arsenal of antibiotics. "Since the introduction of antibiotics in the 1940s, doctors have had to rely on their expertise, intuition, and experience to diagnose patients and initiate antibiotic therapy well before diagnostic test results were available...
The company will launch its breakthrough technology-platform dedicated to identifying next-generation therapeutic peptides
PeptiMimesis, a biopharma company dedicated to the discovery and development of therapeutic transmembrane peptides, today announces the release of the €0.5m ($0.6m) first tranche of a €1.2m ($1.4m) investment made by Cap Innov’Est, a regionally-based seed fund. The company will use this funding to initiate its research activities on the design and characterization of transmembrane peptides...
AMSBIO has released a new 16-page practical guide that provides a detailed overview on how blockers can be used to reduce non-specific binding in immunoassays.
Immunoassay Blocking Reagents (Blockers) are typically applied to ELISA and Lateral Flow-based assays, specifically paired monoclonal sandwich assays, competitive assays and antigen capture (IgG/IgM) assays. They work by removing interfering proteins in patient samples that could produce false results and an incorrect diagnosis. Choosing the best assay format depends on the intended application of the...
Genomics plc have announced that it has entered into a research collaboration with DNAnexus, the global leader in cloud-based genome informatics and data management.
The companies will work together to improve researchers’ ability to analyse population-scale sequencing data. With DNA sequencing costs continuing to fall, sequencing projects involving tens or hundreds of thousands of people are becoming increasingly common. Such projects include Genomics England’s 100,000 Genomes Project, and the Regeneron Genetics Center and Geisinger Health DiscovEHR...
Experimental “Internet of Things” System Uses Connected Devices to Enable Remote Measurement of Health and Quality of Life in Real-Time - Multi-Year Project Could Potentially Change How Clinical Trials are Conducted
Pfizer Inc. (NYSE:PFE) and IBM (NYSE:IBM) today announced a first-of-its-kind research collaboration to develop innovative remote monitoring solutions aimed at transforming how clinicians deliver care to patients suffering from Parkinson’s disease. The experimental approach will rely on a system of sensors, mobile devices, and machine learning to provide real-time, around-the-clock disease symptom information to clinicians and researchers....
Read MoreResearchers put the Paradigm of Endless Endpoint Assays in Biased Agonism Studies to QuestionMay 20, 2016
BMG LABTECH’s Readers are Used to Measure Binding Kinetics Over Minutes
Single reading events of a signaling molecule at a given time should no longer be considered as the only insightful indicator to predict the usefulness of a new drug candidate. In fact, the authors of a new study claim that it is necessary to explore the kinetic context of the binding event instead....
The European Region is the first in the world to have achieved interruption of indigenous malaria transmission.
The number of indigenous malaria cases dropped from 90 712 in 1995 to zero cases in 2015. Ahead of World Malaria Day 2016, WHO announces that the European Region hit its 2015 target to wipe out malaria, thus contributing to the global goal to “End malaria for good”. Key partners funded malaria elimination efforts in European countries substantially. “This is a major milestone in Europe’s public health...
Findings from Sheffield Teaching Hospitals NHS Trust
Beckman Coulter today announced that the Sheffield Teaching Hospitals Virology Department is the first site to introduce the company’s DxN VERIS HBV assay* routinely. Operating on the DxN VERIS Molecular Diagnostics System, that consolidates DNA extraction, amplification and detection within a single automated instrument, the HBV assay will allow the laboratory to offer service users greater precision at...
eMolecules Inc. and World Fusion US, Inc. today announced a global partnership resulting in the integration of eMolecules’ drug discovery ecommerce solutions with World Fusion’s “Life Science Knowledge Bank” (LSKB).
“We are really excited about the opportunities that this partnership creates and we view this as a great start in our vision of enabling the Japanese marketplace to reduce the time and cost of drug discovery” said Dr. Niko Gubernator, CEO at eMolecules, Inc. “Not only does this partnership extend our reach into the Japanese marketplace, but the integration of World Fusion’s LSKB informatics platform with...
Cytocell Chromoprobe Multiprobe® non-human FISH probes set to benefit animal husbandry and research
Oxford Gene Technology (OGT), The Molecular Genetics Company, has developed a new range of non-human fluorescence in situ hybridisation (FISH) probes, for pig, chicken and mouse. The probes were developed as part of an Innovate UK knowledge transfer partnership (KTP) funded project in collaboration with the University of Kent, and was given an ‘outstanding’ award reserved for the top 10% of KTP projects...
GÉANT, Europe?s leading collaboration on network and related infrastructure for research and education, has signed a partnership agreement with Microsoft to act as network connectivity provider for Microsoft?s Azure ExpressRoutes service.
This will connect Microsoft?s cloud services directly to Europe?s vital research and education community, and represents further growth in the portfolio of above-the-net services offered by GÉANT and its National Research and Education Network (NREN) partners to over 50 million users at 10,000 institutions. Microsoft Azure ExpressRoutes enables institutions to extend their on-premises network into the...
PAREXEL enhances its Regulatory Cloud; leverages EMC® Documentum® for Life Sciences software solution suite to offer an end-to-end regulatory solution
PAREXEL International Corporation (NASDAQ: PRXL), a leading global biopharmaceutical services organisation, and EMC Corporation (NYSE: EMC) today announced they have entered into an alliance to offer an end-to-end Regulatory Information Management (RIM) and Regulatory Content Management solution. By combining PAREXEL® LIQUENT InSight® Regulatory Information Management platform...
Researchers at Birmingham University have used Markes’ BenchTOF-Select time-of-flight mass spectrometer in combination with two-dimensional gas chromatography (GC×GC) to improve the separation and identification of hydrocarbons in motor oil.
The paper, entitled ‘Using variable ionisation energy time-of-flight mass spectrometry with comprehensive GC×GC to identify isomeric species’, shows how spectra acquired at 14 eV on BenchTOF-Select can be used to positively identify isomers from the previously unresolved complex mixture (UCM) in these samples. The paper is the first literature citation of Markes’ new Select-eV technology, which uses revolutionary...
Molecular diagnostic approaches to cancer detection and monitoring can benefit from a multiple-template strategy that analyzes DNA from circulating tumor cells (ctcDNA) and circulating cell-free DNA (ccfDNA) in blood, as well as from tissue biopsies, according to a new NCI-supported clinical trial published by scientists from Cynvenio Biosystems, Inc., and collaborators.
The new research was published online in the journal Oncotarget. The findings show that data gained through Next-Generation Sequencing (NGS) of ccfDNA and ctcDNA liquid biopsy templates differ, but complement, each other and should be used in combination. Analysis of each template enables the capture of different moments in a tumor’s evolution, providing additional and complementary information to that provided by...
Particle Metrix, developers of versatile particle characterization solutions for the life sciences, report on the work of the Burger Laboratory at Ottawa Hospital Research Institute.
The Lab is studying the role of microparticles in the pathogenesis of diabetic vascular and kidney disease. Dr Dylan Burger leads a research group at Ottawa Hospital’s Research Institute. Their research focuses on understanding the biological role of membrane vesicles (specifically exosomes and microparticles/microvesicles) in vascular and renal disease. In particular, they are interested in the impact of...
Protein research opens “promising” window into the potential treatment of Alzheimer’s disease
Research co-led by the University of Glasgow has made a potential breakthrough in the treatment of Alzheimer’s disease. The study, led by scientists at the University of Glasgow and the Hong Kong University of Science and Technology (HKUST), has discovered that a protein called IL-33 can reverse Alzheimer’s disease-like pathology and cognitive decline in mice. The research, which is published today in...
Dr Maria Vogt is Professor of Chemistry at Bloomfield College, an undergraduate college in New Jersey. She teaches lectures and runs labs in Organic Chemistry and Biochemistry. Having had a prior research career and publishing more than 45 papers, Dr Vogt now devotes her efforts to prepare students for the "real world" by exposing them to as many hands-on and instrumental skills as possible prior to...
Dr Christine Müller-Renno is a member of the Ziegler Group in the Physics Department at the University of Kaiserslautern in Germany. The main topics of their research are in nano- and microelectronics, as well as in medical engineering and fluid analysis. Other topics include catalysts and stain-resistant coatings by the use of nanomaterials. The Group uses the JPK NanoWizard® AFM to study the...
Sartorius Stedim BioOutsource today announced that its scientific experts will be presenting a live webinar about optimizing biosimilar analysis on Thursday, June 2, at 3 pm BST, 10 am EDT. The webinar is essential listening for researchers who want to understand how to select optimal clones and processes to accelerate development of their biosimilars. During the one-hour webinar, Dr. Martin De Cecco, and...
The solution leverages each company’s respective expertise, and consists of BioTek’s new Lionheart™ FX Automated Live Cell Imager and Merck’s new CellASIC® ONIX2 Microfluidic System. This collaborative solution was introduced at the American Association of Cancer Research (AACR) Annual Meeting recently held in New Orleans, LA. The Lionheart FX Automated Live Cell Imager is optimized for live cell...
This deal is the result of a highly productive collaboration between ARGENX, a biotech company, and the teams of Professors Pierre Coulie and Sophie Lucas of the Université catholique de Louvain (UCL), who are recognized worldwide as leaders in the field of immuno-oncology. This collaboration has resulted in an innovative therapeutic approach to stimulate the immune system of cancer patients...
Cepheid (Nasdaq: CPHD) have announced the launch of its 'Diagnostics First' campaign to raise awareness for the use of accurate and fast diagnostic tests to inform optimal treatment decisions and avoid over-prescription of the world's limited arsenal of antibiotics. "Since the introduction of antibiotics in the 1940s, doctors have had to rely on their expertise, intuition, and experience to diagnose patients and initiate antibiotic therapy well before diagnostic test results were available...
PeptiMimesis, a biopharma company dedicated to the discovery and development of therapeutic transmembrane peptides, today announces the release of the €0.5m ($0.6m) first tranche of a €1.2m ($1.4m) investment made by Cap Innov’Est, a regionally-based seed fund. The company will use this funding to initiate its research activities on the design and characterization of transmembrane peptides...
Immunoassay Blocking Reagents (Blockers) are typically applied to ELISA and Lateral Flow-based assays, specifically paired monoclonal sandwich assays, competitive assays and antigen capture (IgG/IgM) assays. They work by removing interfering proteins in patient samples that could produce false results and an incorrect diagnosis. Choosing the best assay format depends on the intended application of the...
The companies will work together to improve researchers’ ability to analyse population-scale sequencing data. With DNA sequencing costs continuing to fall, sequencing projects involving tens or hundreds of thousands of people are becoming increasingly common. Such projects include Genomics England’s 100,000 Genomes Project, and the Regeneron Genetics Center and Geisinger Health DiscovEHR...
Pfizer Inc. (NYSE:PFE) and IBM (NYSE:IBM) today announced a first-of-its-kind research collaboration to develop innovative remote monitoring solutions aimed at transforming how clinicians deliver care to patients suffering from Parkinson’s disease. The experimental approach will rely on a system of sensors, mobile devices, and machine learning to provide real-time, around-the-clock disease symptom information to clinicians and researchers....
Single reading events of a signaling molecule at a given time should no longer be considered as the only insightful indicator to predict the usefulness of a new drug candidate. In fact, the authors of a new study claim that it is necessary to explore the kinetic context of the binding event instead....
The number of indigenous malaria cases dropped from 90 712 in 1995 to zero cases in 2015. Ahead of World Malaria Day 2016, WHO announces that the European Region hit its 2015 target to wipe out malaria, thus contributing to the global goal to “End malaria for good”. Key partners funded malaria elimination efforts in European countries substantially. “This is a major milestone in Europe’s public health...
Beckman Coulter today announced that the Sheffield Teaching Hospitals Virology Department is the first site to introduce the company’s DxN VERIS HBV assay* routinely. Operating on the DxN VERIS Molecular Diagnostics System, that consolidates DNA extraction, amplification and detection within a single automated instrument, the HBV assay will allow the laboratory to offer service users greater precision at...
“We are really excited about the opportunities that this partnership creates and we view this as a great start in our vision of enabling the Japanese marketplace to reduce the time and cost of drug discovery” said Dr. Niko Gubernator, CEO at eMolecules, Inc. “Not only does this partnership extend our reach into the Japanese marketplace, but the integration of World Fusion’s LSKB informatics platform with...
Oxford Gene Technology (OGT), The Molecular Genetics Company, has developed a new range of non-human fluorescence in situ hybridisation (FISH) probes, for pig, chicken and mouse. The probes were developed as part of an Innovate UK knowledge transfer partnership (KTP) funded project in collaboration with the University of Kent, and was given an ‘outstanding’ award reserved for the top 10% of KTP projects...
This will connect Microsoft?s cloud services directly to Europe?s vital research and education community, and represents further growth in the portfolio of above-the-net services offered by GÉANT and its National Research and Education Network (NREN) partners to over 50 million users at 10,000 institutions. Microsoft Azure ExpressRoutes enables institutions to extend their on-premises network into the...
PAREXEL International Corporation (NASDAQ: PRXL), a leading global biopharmaceutical services organisation, and EMC Corporation (NYSE: EMC) today announced they have entered into an alliance to offer an end-to-end Regulatory Information Management (RIM) and Regulatory Content Management solution. By combining PAREXEL® LIQUENT InSight® Regulatory Information Management platform...
The paper, entitled ‘Using variable ionisation energy time-of-flight mass spectrometry with comprehensive GC×GC to identify isomeric species’, shows how spectra acquired at 14 eV on BenchTOF-Select can be used to positively identify isomers from the previously unresolved complex mixture (UCM) in these samples. The paper is the first literature citation of Markes’ new Select-eV technology, which uses revolutionary...
The new research was published online in the journal Oncotarget. The findings show that data gained through Next-Generation Sequencing (NGS) of ccfDNA and ctcDNA liquid biopsy templates differ, but complement, each other and should be used in combination. Analysis of each template enables the capture of different moments in a tumor’s evolution, providing additional and complementary information to that provided by...
The Lab is studying the role of microparticles in the pathogenesis of diabetic vascular and kidney disease. Dr Dylan Burger leads a research group at Ottawa Hospital’s Research Institute. Their research focuses on understanding the biological role of membrane vesicles (specifically exosomes and microparticles/microvesicles) in vascular and renal disease. In particular, they are interested in the impact of...
Research co-led by the University of Glasgow has made a potential breakthrough in the treatment of Alzheimer’s disease. The study, led by scientists at the University of Glasgow and the Hong Kong University of Science and Technology (HKUST), has discovered that a protein called IL-33 can reverse Alzheimer’s disease-like pathology and cognitive decline in mice. The research, which is published today in...