Secondary school pupils from across the north of Scotland have been experimenting with science over the past month as Robert Gordon University (RGU) continues its tradition of widening access to STEM subjects from an early age.
Members of RGU’s School of Pharmacy and Life Sciences have held a number of events in recent weeks to engage with youngsters and imprint the scientific curiosity that can take them far in their future careers. It began with the celebration for National Pathology Week, where...
SP Scientific announces publication of an independent study evaluating their LyoCapsule™ Freeze Dryer for pharmaceutical product formulation and process development.
The development of biopharmaceuticals often requires lyophilized formulations to produce stable drug products, beginning with laboratory experiments followed by scale-up to larger lyophilizers. Limited supply and high cost of Active Pharmaceutical Ingredient (API) can present major challenges during formulation and process development....
€1.6 million grant will support ‘precise docking of very large DNA cargoes in genomes’ project
Sphere Fluidics, a company providing single cell analysis systems underpinned by its patented picodroplet technology, and Geneva Biotech, an EMBL spin-out developing world-class viral and non-viral DNA delivery systems, have received a €1.6 million grant from Eurostars....
The WHO reports an estimated 429,000 malaria deaths each year.
The disease mostly affects tropical and subtropical regions and in particular the African continent. The Fraunhofer Institute for Silicate Research ISC teamed up with the Fraunhofer Institute for Molecular Biology and Applied Ecology IME and the Institute of Tropical Medicine at the University of Tübingen....
The Bundesanstalt für Materialforschung und -prüfung (Federal Institute for Materials Research and Testing, BAM) and Analytik Jena AG have agreed to cooperate extensively in the research and development of optical spectrometry in the area of elemental analysis.
The two parties signed a corresponding cooperation agreement last week in Berlin. The focus of the two partners’ future research efforts will be on the development of new devices and applications for element determination. In this connection, the teams will work jointly on the further development...
University of Leicester and Medical Research Council researchers lead study to monitor effectiveness of drugs on cancer patients
University and MRC researchers have developed a new platform for assessing anti-cancer drug efficacy in lung cancer that is more reflective of patient response than previously used model systems. The platform relies on the derivation of ‘explants’ from tumour tissue obtained fresh from surgery....
Uniqsis has published an application note that describes an efficient 2-step synthesis of a library of pyrazoles under continuous flow-through conditions developed by chemists at GalChimia (Coruna, Spain) on a FlowSyn™ continuous flow reactor system.
Pyrazoles are an important and well represented chemotype in drug discovery displaying wide ranging biological actions that include analgesic, anti-inflammatory, antipyretic, tranquilizing, muscle relaxing, anticonvulsant, antidiabetic and antibacterial activities....
While colorectal cancer screening already saves many thousands of lives, there is still room for improvement.
By looking at a combination of specific proteins rather than at a single blood protein alone, substantially more patients with colorectal cancer and advanced adenomas could be detected. The study describing these findings, conducted by researchers from the Netherlands Cancer Institute and VU University Medical Center....
New application note gives researchers insights and guidance on maximizing HDR-mediated insertion of short fragments in CRISPR genome editing
As an advocate for the genomics age, Integrated DNA Technologies (IDT), has published a new application note on optimization of CRISPR-Cas9 for homology-directed repair (HDR) applications. Available as part of the IDT collection of CRISPR application notes and protocols, this article supports researchers using CRISPR...
Melbourne-based melanoma researcher selected as the winner of ‘RNAscope ISH Get Hybridized’ giveaway, supporting cutting-edge research
Advanced Cell Diagnostics (ACD), a Bio-Techne brand, has announced the winner of its ‘RNAscope ISH Get Hybridized’ giveaway, designed to recognize and support groundbreaking research with RNAscope®in situ hybridization (ISH) technology. The winner, Dr. Andreas Behren, Group Leader in Cancer Immunobiology....
Leeds Beckett University and global research and development company, Axxonet Global, have announced an official partnership which will see the organisations collaborate on cutting-edge medical diagnostics and technology, forensic science and digital security projects.
The signing of an official Memorandum of Understanding (MoU) agreement follows the successful work that Leeds Beckett has been carrying out with Axxonet Global Limited and its Indian partner, Axxonet System Technologies India, over the last year, developing assistive technologies for medical systems, supporting age-related disorders and Parkinson’s disease. The partner organisations will engage in joint research and development projects in the areas of...
Researchers at Kanazawa University and the University of Tokyo report in Nature Communications the visualization of the dynamics of ‘molecular scissors’ — the main mechanism of the CRISPR-Cas9 genetic-engineering technique.
One of the techniques used in genetic engineering — the process of artificially modifying the genome of a living organism — involves the so-called CRISPR-Cas9 nuclease system. Using this system, a cell’s DNA can be cut at a desired site, where genes can be deleted or added....
High resolution 3D block face imaging for biological samples with fast acquisition rates and minimal sample damage
In collaboration with the National Center for Microscopy and Imaging Research (NCMIR) at the University of California San Diego, ZEISS releases a new Focal Charge Compensation module for block face imaging with ZEISS GeminiSEM and 3View® from Gatan, Inc....
Palm oil is widely used in the food industry, for example in products such as margarine, spreads, chocolate, or pure as oil.
Various studies carried out during the last years have proven the presence of 3-monochloropropane-1, 2-diol (3-MCPD) fatty acid ester in refined palm oil, which is suspected to raise the risk of cancer. 3-MCPD is formed when fats and oils are exposed to high temperatures, in the presence of organic and inorganic bound chlorine....
Biotechnology Group at the University of Leicester working in collaboration with spin-out company MIP Diagnostics Ltd
Experts from the Biotechnology Group at the University of Leicester led by Professor Sergey Piletsky in collaboration with the spin-off company MIP Diagnostics Ltd have announced the development of polymeric materials with molecular recognition capabilities which hold the potential to outperform natural antibodies....
Join Precision NanoSystems for a roundtable discussion on nanomedicines as part of the 3rd International Electronic Conference on Medicinal Chemistry.
Organised by Pharmaceuticals journal, this free online conference runs until November 30th, and deals with all aspects of research in drug discovery and development. As a partner of the event, Precision NanoSystems is hosting a virtual roundtable, providing an opportunity to discuss the current hot topics in nanomedicine research....
A leading European manufacturer of health products is benefiting from the control capabilities of peristaltic pumps from Watson-Marlow Fluid Technology Group (WMFTG).
The pumps are being used for the precise metering of water-based buffer agents such as hydrogen chloride (HCl) and glycerol, at one of its production facilities on the island of Sicily. Established in 1946, Fidia Farmaceutici SpA is headquartered in Abano Terne near Padua, Italy....
Deben reports on how Luleå University of Technology is using their CT5000TEC compression/tensile stage with integrated temperature control to improve the understanding of deformation and strain under different loads and temperatures.
This work is being performed in a ZEISS Xradia 510 Versa 3D x-ray microscope. Dr Fredrik Forsberg is an Associate Senior Lecturer in the Department of Engineering Sciences & Mathematics at Luleå University of Technology (LTU) in Sweden. His research goal at the x-ray microtomography lab...
NeoGenomics Inc. a leading global specialty oncology testing laboratory, opened the doors of its new Rolle, Switzerland facility on Wednesday, November 8th to bring its unique Pharma Services offering to the global research community.
Rolle was chosen as NeoGenomics’ European Headquarters because of the existing talent pool, favorable business environment, and proximity to leading academic institutions in Geneva and Lausanne. The event kicked off with a ribbon-cutting ceremony and remarks by NeoGenomics’ Chairman and CEO, Douglas VanOort...
Porvair Sciences has published an informative video demonstrating how to use a solid-state filter microplate to remove interfering proteins from serum, plasma or even whole blood samples prior to analysis by LC/MS
Biological samples commonly contain proteins that interfere with downstream applications. The Porvair Sciences Protein Precipitation Plate (P3) plate uses the CRASH method, in which the protein is denatured with acetronitrile and the flocculant filtered out, allowing 96 samples to be handled at one time....
Read MoreThe MRC CLIMB Project Receives Honours in 2017 HPCwire Reader's and Editor's Choice AwardsNov 21, 2017
The MRC-funded Cloud Infrastructure for Microbial Bioinformatics (CLIMB) has been recognized in the annual HPCwire Readers’ and Editors’ Choice Awards
CLIMB was awarded the following honours - “Best Use of HPC in Life Sciences” for Real-Time analysis of Zika genomes, supported by Lenovo, OpenStack, IBM, Red Hat and Dell EMC and “Best HPC Collaboration (Academia/Government/Industry)” for CLIMB drawing on Lenovo...
In April 2018, changes to energy efficiency regulations will mean that every non-domestic privately rented property must have an energy performance certificate (EPC) rating of at least an E. Energy efficiency is vital in meeting regulations, cutting costs and minimising carbon emissions....
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Members of RGU’s School of Pharmacy and Life Sciences have held a number of events in recent weeks to engage with youngsters and imprint the scientific curiosity that can take them far in their future careers. It began with the celebration for National Pathology Week, where...
The development of biopharmaceuticals often requires lyophilized formulations to produce stable drug products, beginning with laboratory experiments followed by scale-up to larger lyophilizers. Limited supply and high cost of Active Pharmaceutical Ingredient (API) can present major challenges during formulation and process development....
Sphere Fluidics, a company providing single cell analysis systems underpinned by its patented picodroplet technology, and Geneva Biotech, an EMBL spin-out developing world-class viral and non-viral DNA delivery systems, have received a €1.6 million grant from Eurostars....
The disease mostly affects tropical and subtropical regions and in particular the African continent. The Fraunhofer Institute for Silicate Research ISC teamed up with the Fraunhofer Institute for Molecular Biology and Applied Ecology IME and the Institute of Tropical Medicine at the University of Tübingen....
The two parties signed a corresponding cooperation agreement last week in Berlin. The focus of the two partners’ future research efforts will be on the development of new devices and applications for element determination. In this connection, the teams will work jointly on the further development...
University and MRC researchers have developed a new platform for assessing anti-cancer drug efficacy in lung cancer that is more reflective of patient response than previously used model systems. The platform relies on the derivation of ‘explants’ from tumour tissue obtained fresh from surgery....
Pyrazoles are an important and well represented chemotype in drug discovery displaying wide ranging biological actions that include analgesic, anti-inflammatory, antipyretic, tranquilizing, muscle relaxing, anticonvulsant, antidiabetic and antibacterial activities....
By looking at a combination of specific proteins rather than at a single blood protein alone, substantially more patients with colorectal cancer and advanced adenomas could be detected. The study describing these findings, conducted by researchers from the Netherlands Cancer Institute and VU University Medical Center....
As an advocate for the genomics age, Integrated DNA Technologies (IDT), has published a new application note on optimization of CRISPR-Cas9 for homology-directed repair (HDR) applications. Available as part of the IDT collection of CRISPR application notes and protocols, this article supports researchers using CRISPR...
Advanced Cell Diagnostics (ACD), a Bio-Techne brand, has announced the winner of its ‘RNAscope ISH Get Hybridized’ giveaway, designed to recognize and support groundbreaking research with RNAscope® in situ hybridization (ISH) technology. The winner, Dr. Andreas Behren, Group Leader in Cancer Immunobiology....
The signing of an official Memorandum of Understanding (MoU) agreement follows the successful work that Leeds Beckett has been carrying out with Axxonet Global Limited and its Indian partner, Axxonet System Technologies India, over the last year, developing assistive technologies for medical systems, supporting age-related disorders and Parkinson’s disease. The partner organisations will engage in joint research and development projects in the areas of...
One of the techniques used in genetic engineering — the process of artificially modifying the genome of a living organism — involves the so-called CRISPR-Cas9 nuclease system. Using this system, a cell’s DNA can be cut at a desired site, where genes can be deleted or added....
High resolution 3D block face imaging for biological samples with fast acquisition rates and minimal sample damage
Various studies carried out during the last years have proven the presence of 3-monochloropropane-1, 2-diol (3-MCPD) fatty acid ester in refined palm oil, which is suspected to raise the risk of cancer. 3-MCPD is formed when fats and oils are exposed to high temperatures, in the presence of organic and inorganic bound chlorine....
Experts from the Biotechnology Group at the University of Leicester led by Professor Sergey Piletsky in collaboration with the spin-off company MIP Diagnostics Ltd have announced the development of polymeric materials with molecular recognition capabilities which hold the potential to outperform natural antibodies....
The pumps are being used for the precise metering of water-based buffer agents such as hydrogen chloride (HCl) and glycerol, at one of its production facilities on the island of Sicily. Established in 1946, Fidia Farmaceutici SpA is headquartered in Abano Terne near Padua, Italy....
Deben reports on how Luleå University of Technology is using their CT5000TEC compression/tensile stage with integrated temperature control to improve the understanding of deformation and strain under different loads and temperatures. 
Rolle was chosen as NeoGenomics’ European Headquarters because of the existing talent pool, favorable business environment, and proximity to leading academic institutions in Geneva and Lausanne. The event kicked off with a ribbon-cutting ceremony and remarks by NeoGenomics’ Chairman and CEO, Douglas VanOort...
Biological samples commonly contain proteins that interfere with downstream applications. The Porvair Sciences Protein Precipitation Plate (P3) plate uses the CRASH method, in which the protein is denatured with acetronitrile and the flocculant filtered out, allowing 96 samples to be handled at one time....
