Biotech Fluidics has published a practical review paper that demonstrates how its MarvelX™ and MarvelXACT™ high pressure fluidic connections enable users to achieve reliable, repeatable, and consistent UHPLC performance. In this paper, fluidic experts explore the connection challenges facing users of modern UHPLC instruments. One of the biggest challenges in designing high performance fluidic connections for UHPLC is ensuring a reliable seal at the bottom of the connection port...
Agilent Technologies Inc. has announced the opening of a new full-scale Integrated Biology Center located at Monash University in Malaysia, focused on building local capabilities to accelerate research and development (R&D) in the field of science. The inauguration was held in conjunction with the company’s Academia-Industrial Day 2023, hosting distinguished guests from the research community...
Oligonucleotides must be of high purity when used within molecular biology applications such as qPCR, next-generation sequencing, and microarray analysis. In the following application note, Gilson explore how the VERITY® Oligo Purification System, configured with automated preparative and analytical HPLC capabilities, can be a solution to isolate, analyze, and desalt reagent-grade oligonucleotides in one continuous run...
LEEUWENHOEK’S THIRD CENTURY - Revealing the Sights of the Seventeenth Century by Brian J Ford Hon FRMS, Hon FLS. There was much excitement around the world when I revealed one of the most extraordinary revelations of my entire academic life – the original microscope specimens, prepared by Antony van Leeuwenhoek in the 1600s, had survived intact. They lay secure in folded paper envelopes hidden among his letters to London, and carefully preserved at the Royal Society...
PacBio, a leading developer of high-quality, highly accurate sequencing solutions and GeneDx, a leader in delivering improved health outcomes through genomic and clinical insights, have announced a research collaboration with the University of Washington to study the capabilities of HiFi long-read whole genome sequencing (WGS) to increase diagnostic rates in pediatric patients with genetic conditions...
BioServe Space Technologies at the University of Colorado Boulder and Sierra Space have developed a pathfinder spaceflight investigation designed to expand hematopoietic stem cells (stem cells that develop into blood cells) derived from umbilical cord blood in microgravity. The project is being done in partnership with researchers from the Mayo Clinic (Jacksonville, Florida) and ClinImmune on the University of Colorado Medical Campus...
When working within a life sciences laboratory one of the most important assets is your samples. This is why it is imperative to preserve, store and retrieve samples while maintaining their integrity. With any large store or “library” of compounds or other samples, being able to easily retrieve a specified sub-set of samples is key to any research workflow - this is the so-called “pick list.” A new technical paper from Ziath describes how their Mirage 2D tube rack reader and Mohawk semi-automated tube picker...
To enhance the reproducibility of flow chemistry scale-up - precise control of mixing and temperature in highly exothermic or rapid reactions in particular is essential. The expanding range of Glass Static Mixer (GSM) chip reactor blocks from Uniqsis produce an efficient, turbulent mixed reagent stream for flow chemistry reactions that is not diffusion dependent. Available in sizes from 270µl to 20 ml, the Uniqsis range of high-quality GSM chips can be used to perform reactions from -80°C to over 150°C...
A new study demonstrates how the combination of DNA-encoded libraries (DELs) and NanoBRET Target Engagement technology can accelerate early-stage drug discovery. Reported in Cell Chemical Biology, researchers from Promega Corporation and WuXi AppTec generated new chemical probes from molecules identified through a DEL screen. This research opens new opportunities to develop novel NanoBRET Target Engagement Assays aimed at many understudied classes of proteins, rapidly accelerating “hit to lead” efforts in identifying new potential therapeutics...
A major milestone towards the redefinition of the second has been achieved by scientists at the National Physical Laboratory (NPL) with the first inclusion of a UK optical frequency standard (NPL-Sr1) in the determination of International Atomic Time (TAI). Calculating TAI is a major resource for determining Coordinated Universal Time (UTC), the shared international reference time scale that countries worldwide use to synchronise clocks...
Elsevier, a global leader in scientific information and data analytics, releases an alpha version of Scopus AI for researcher testing – a next generation tool that combines generative AI with Scopus' trusted content and data to help researchers get deeper insights faster, support collaboration and societal impact of research. For more than a decade, Elsevier has been using AI and machine learning technologies responsibly in its products combined with its unparalleled peer-reviewed content, extensive data sets, and sophisticated analytics...
California Seed and Plant (CSP) Labs, a leading private plant pathology and genetics testing laboratory in California, is using VIAFLO 96 and VIAFLO 384 handheld electronic pipettes from INTEGRA Biosciences to streamline its nucleic acid extraction and sample processing workflows. These 24, 96 and 384 channel pipettes are used to help assess seed, plant and soil health with greater efficiency and reproducibility, supporting innovations in the agricultural industry to keep up with rising global food demands...
The automation of laboratories used to be considered very costly and not very flexible, because the workflows are very complex and amounts of data are constantly increasing. Yet, as chemical and pharmaceutical industry product lifecycles become shorter and shorter, the need for digitalization has become urgent. In this article, Christof Franzke, Senior Technical Consultant Key Accounts at COPA-DATA, the industrial software specialist, explains the vital role of the zenon platform in the roll-out of modularization and digitalization in laboratories...
Accelerated Technology Laboratories, Inc. (ATL), a leader in Laboratory Information Management Systems (LIMS), continues the 2023 LIMS Webcast Series on Wednesday, August 9, with Why We Love LIMS: ATL Customers Tell Their LIMS Success Stories. Feedback from webcast attendees has always been very positive when we invite ATL LIMS clients to share their views on how a LIMS has become an essential component of their laboratory operations...
Scientists and engineers at the National Physical Laboratory (NPL)are working with colleagues at the Science and Technology Facilities Council’s (STFC) RAL Space to deliver a small satellite calibration facility. The new facility is being designed, manufactured and tested at NPL’s Teddington site in south-west London and will be located at Harwell Campus. It will draw on expertise from NPL’s STAR-cc-OGSE facility, which provides innovative solutions for calibrating scientific instruments on satellites before their launch into space...
A £5 million award from the UK Space Agency will allow Northumbria University to take forward world-leading research to build a new satellite communications system, setting the scene for Northumbria to launch the UK’s first university-led multi-satellite space mission. The funding announcement made today allow the University to move forward with its prototype work on this new laser-based system, which has the potential to transform the satellite communications industry...
Illumina Inc., a global leader in DNA sequencing and array-based technologies, in collaboration with Nashville Biosciences, LLC, a leading clinical and genomic data company and wholly owned subsidiary of Vanderbilt University Medical Center (VUMC), has announced the five founding members of the Alliance for Genomic Discovery (AGD). The multiyear agreement aims to accelerate development of therapeutics through large-scale genomics and the establishment of a preeminent clinical genomic resource...
Despite recommendations from the European Society for Medical Oncology and the EU Beating Cancer Plan, uptake of next-generation sequencing (NGS) in lung cancer remains slow and inequitable across Europe. In the first report of its kind, experts highlight action needed to correct disparity in access to a gold-standard diagnostic technology that could benefit tens of thousands of lung cancer patients across Europe every year...
In 2022, raw sewage was pumped into English rivers and seas for 1.75 million hours, or 200 cumulative years. Despite awareness of the need for environmental safeguarding growing every year, UK waterways still suffer pollution of the foulest kind. And it isn’t only sewage that waste companies have to worry about: here Matt Allen, product manager for elemental analysers at SciMed, the UK’s largest distributor of lab equipment, explains why testing water for halogen species will be a serious consideration in the near future...
Discovery Park, in Sandwich, Kent has launched a new business support programme and competition, ‘Discovery Spark’. Discovery Spark is currently accepting applications from life-science start-ups, with a closing deadline of 20 August. From the first cohort of up to 12 companies, one business will be selected to win a prize package worth over £100,000, including £50,000 investment from Discovery Park Ventures, 1 year of free lab space at Discovery Park, plus wrap-around business support and dedicated mentoring...
Researchers are set to to combine expertise in drug discovery, artificial intelligence (AI), and experimental cancer models and platforms in a new programme to design the precision cancer drugs of the future. Under an academic and commercial collaboration between The Institute of Cancer Research, London, the Bellvitge Biomedical Research Institute (IDIBELL), Barcelona, and the company Vivan Therapeutics, a multi-disciplijnary team will seek to create drugs that can counteract drug resistance...
NK:IO, a leader in NK cell biology applied to the development of exceptionally potent, off-the-shelf cell therapies targeting solid tumours, has announced it has been awarded £1.6M in grant funding from Innovate UK’s New Cancer Therapeutics program. The funding will support preclinical development, including development of a manufacturing process in collaboration with the Cell and Gene Therapy Catapult, whose mission is to support the UK’s cell and gene therapy industry...
Biotech Fluidics has published a practical review paper that demonstrates how its MarvelX™ and MarvelXACT™ high pressure fluidic connections enable users to achieve reliable, repeatable, and consistent UHPLC performance. In this paper, fluidic experts explore the connection challenges facing users of modern UHPLC instruments. One of the biggest challenges in designing high performance fluidic connections for UHPLC is ensuring a reliable seal at the bottom of the connection port...
Agilent Technologies Inc. has announced the opening of a new full-scale Integrated Biology Center located at Monash University in Malaysia, focused on building local capabilities to accelerate research and development (R&D) in the field of science. The inauguration was held in conjunction with the company’s Academia-Industrial Day 2023, hosting distinguished guests from the research community...
Oligonucleotides must be of high purity when used within molecular biology applications such as qPCR, next-generation sequencing, and microarray analysis. In the following application note, Gilson explore how the VERITY® Oligo Purification System, configured with automated preparative and analytical HPLC capabilities, can be a solution to isolate, analyze, and desalt reagent-grade oligonucleotides in one continuous run...
LEEUWENHOEK’S THIRD CENTURY - Revealing the Sights of the Seventeenth Century by Brian J Ford Hon FRMS, Hon FLS. There was much excitement around the world when I revealed one of the most extraordinary revelations of my entire academic life – the original microscope specimens, prepared by Antony van Leeuwenhoek in the 1600s, had survived intact. They lay secure in folded paper envelopes hidden among his letters to London, and carefully preserved at the Royal Society...
PacBio, a leading developer of high-quality, highly accurate sequencing solutions and GeneDx, a leader in delivering improved health outcomes through genomic and clinical insights, have announced a research collaboration with the University of Washington to study the capabilities of HiFi long-read whole genome sequencing (WGS) to increase diagnostic rates in pediatric patients with genetic conditions...
BioServe Space Technologies at the University of Colorado Boulder and Sierra Space have developed a pathfinder spaceflight investigation designed to expand hematopoietic stem cells (stem cells that develop into blood cells) derived from umbilical cord blood in microgravity. The project is being done in partnership with researchers from the Mayo Clinic (Jacksonville, Florida) and ClinImmune on the University of Colorado Medical Campus...
When working within a life sciences laboratory one of the most important assets is your samples. This is why it is imperative to preserve, store and retrieve samples while maintaining their integrity. With any large store or “library” of compounds or other samples, being able to easily retrieve a specified sub-set of samples is key to any research workflow - this is the so-called “pick list.” A new technical paper from Ziath describes how their Mirage 2D tube rack reader and Mohawk semi-automated tube picker...
To enhance the reproducibility of flow chemistry scale-up - precise control of mixing and temperature in highly exothermic or rapid reactions in particular is essential. The expanding range of Glass Static Mixer (GSM) chip reactor blocks from Uniqsis produce an efficient, turbulent mixed reagent stream for flow chemistry reactions that is not diffusion dependent. Available in sizes from 270µl to 20 ml, the Uniqsis range of high-quality GSM chips can be used to perform reactions from -80°C to over 150°C...
A new study demonstrates how the combination of DNA-encoded libraries (DELs) and NanoBRET Target Engagement technology can accelerate early-stage drug discovery. Reported in Cell Chemical Biology, researchers from Promega Corporation and WuXi AppTec generated new chemical probes from molecules identified through a DEL screen. This research opens new opportunities to develop novel NanoBRET Target Engagement Assays aimed at many understudied classes of proteins, rapidly accelerating “hit to lead” efforts in identifying new potential therapeutics...
A major milestone towards the redefinition of the second has been achieved by scientists at the National Physical Laboratory (NPL) with the first inclusion of a UK optical frequency standard (NPL-Sr1) in the determination of International Atomic Time (TAI). Calculating TAI is a major resource for determining Coordinated Universal Time (UTC), the shared international reference time scale that countries worldwide use to synchronise clocks...
Elsevier, a global leader in scientific information and data analytics, releases an alpha version of Scopus AI for researcher testing – a next generation tool that combines generative AI with Scopus' trusted content and data to help researchers get deeper insights faster, support collaboration and societal impact of research. For more than a decade, Elsevier has been using AI and machine learning technologies responsibly in its products combined with its unparalleled peer-reviewed content, extensive data sets, and sophisticated analytics...
California Seed and Plant (CSP) Labs, a leading private plant pathology and genetics testing laboratory in California, is using VIAFLO 96 and VIAFLO 384 handheld electronic pipettes from INTEGRA Biosciences to streamline its nucleic acid extraction and sample processing workflows. These 24, 96 and 384 channel pipettes are used to help assess seed, plant and soil health with greater efficiency and reproducibility, supporting innovations in the agricultural industry to keep up with rising global food demands...
The automation of laboratories used to be considered very costly and not very flexible, because the workflows are very complex and amounts of data are constantly increasing. Yet, as chemical and pharmaceutical industry product lifecycles become shorter and shorter, the need for digitalization has become urgent. In this article, Christof Franzke, Senior Technical Consultant Key Accounts at COPA-DATA, the industrial software specialist, explains the vital role of the zenon platform in the roll-out of modularization and digitalization in laboratories...
Accelerated Technology Laboratories, Inc. (ATL), a leader in Laboratory Information Management Systems (LIMS), continues the 2023 LIMS Webcast Series on Wednesday, August 9, with Why We Love LIMS: ATL Customers Tell Their LIMS Success Stories. Feedback from webcast attendees has always been very positive when we invite ATL LIMS clients to share their views on how a LIMS has become an essential component of their laboratory operations...
Scientists and engineers at the National Physical Laboratory (NPL)are working with colleagues at the Science and Technology Facilities Council’s (STFC) RAL Space to deliver a small satellite calibration facility. The new facility is being designed, manufactured and tested at NPL’s Teddington site in south-west London and will be located at Harwell Campus. It will draw on expertise from NPL’s STAR-cc-OGSE facility, which provides innovative solutions for calibrating scientific instruments on satellites before their launch into space...
A £5 million award from the UK Space Agency will allow Northumbria University to take forward world-leading research to build a new satellite communications system, setting the scene for Northumbria to launch the UK’s first university-led multi-satellite space mission. The funding announcement made today allow the University to move forward with its prototype work on this new laser-based system, which has the potential to transform the satellite communications industry...
Illumina Inc., a global leader in DNA sequencing and array-based technologies, in collaboration with Nashville Biosciences, LLC, a leading clinical and genomic data company and wholly owned subsidiary of Vanderbilt University Medical Center (VUMC), has announced the five founding members of the Alliance for Genomic Discovery (AGD). The multiyear agreement aims to accelerate development of therapeutics through large-scale genomics and the establishment of a preeminent clinical genomic resource...
Despite recommendations from the European Society for Medical Oncology and the EU Beating Cancer Plan, uptake of next-generation sequencing (NGS) in lung cancer remains slow and inequitable across Europe. In the first report of its kind, experts highlight action needed to correct disparity in access to a gold-standard diagnostic technology that could benefit tens of thousands of lung cancer patients across Europe every year...
In 2022, raw sewage was pumped into English rivers and seas for 1.75 million hours, or 200 cumulative years. Despite awareness of the need for environmental safeguarding growing every year, UK waterways still suffer pollution of the foulest kind. And it isn’t only sewage that waste companies have to worry about: here Matt Allen, product manager for elemental analysers at SciMed, the UK’s largest distributor of lab equipment, explains why testing water for halogen species will be a serious consideration in the near future...
Discovery Park, in Sandwich, Kent has launched a new business support programme and competition, ‘Discovery Spark’. Discovery Spark is currently accepting applications from life-science start-ups, with a closing deadline of 20 August. From the first cohort of up to 12 companies, one business will be selected to win a prize package worth over £100,000, including £50,000 investment from Discovery Park Ventures, 1 year of free lab space at Discovery Park, plus wrap-around business support and dedicated mentoring...
Researchers are set to to combine expertise in drug discovery, artificial intelligence (AI), and experimental cancer models and platforms in a new programme to design the precision cancer drugs of the future. Under an academic and commercial collaboration between The Institute of Cancer Research, London, the Bellvitge Biomedical Research Institute (IDIBELL), Barcelona, and the company Vivan Therapeutics, a multi-disciplijnary team will seek to create drugs that can counteract drug resistance...
NK:IO, a leader in NK cell biology applied to the development of exceptionally potent, off-the-shelf cell therapies targeting solid tumours, has announced it has been awarded £1.6M in grant funding from Innovate UK’s New Cancer Therapeutics program. The funding will support preclinical development, including development of a manufacturing process in collaboration with the Cell and Gene Therapy Catapult, whose mission is to support the UK’s cell and gene therapy industry...