Special Offers & Promotions



Latest News



View Channel

New Products



View Channel

Video Presentations



View Channel

Separation Science



View Channel

Microscopy & Image Analysis



View Channel

Laboratory Automation & IT Solutions



View Channel


New Promega Kit Enables European Forensic Labs to Solve Challenging Cold Cases

publication date: May 24, 2024
author/source: Promega UK Ltd


  • Eight-colour kit provides more usable information from degraded or inhibited DNA samples
  • Includes all DNA markers recommended by the European Network of Forensic Science Institutes (ENFSI)
  • Promega is the first manufacturer to produce eight-color chemistry for forensic DNA analysis


Forensic laboratories in Europe now have a new DNA analysis kit to efficiently process challenging casework samples. The PowerPlex® 18E System, launched by Promega Corporation, uses eight-colour short tandem repeat (STR) analysis chemistry to extract more usable information from challenging samples. The kit includes all DNA markers recommended by the European Network of Forensic Science Institutes (ENFSI).

“Different regions have their own legal requirements and databases, as well as distinct genetic variations in their populations,” says Anupama Gopalakrishnan, Senior Product Manager at Promega Corporation. “This kit meets European forensic laboratories’ unique needs while also giving them more information from challenging DNA samples compared to earlier chemistries.”


Next-generation eight-colour STR kits 

STR analysis is the most widely used tool in human identification efforts. Most kits rely on five or six colours of dyes to mark regions of DNA that can help identify a match. Promega introduced the first commercially available eight-colour STR multiplex chemistry in 2023 and expands on that product family with the PowerPlex® 18E System. 

PowerPlex® 18E System features include: 

  • 18 loci aligned with recommendations from ENFSI: The kit includes the SE33 locus, which has been shown to be particularly informative for analysing DNA samples from European populations. At 170-324 base pairs, the size of the SE33 locus is the smallest of all commercially available multiplexes. 
  • All loci amplicons less than 325 base pairs in length: Shorter amplicons are less likely to disappear during STR analysis, helping labs avoid data loss when working with degraded or limited samples. 
  • Quality indicators for efficient troubleshooting: If an experiment fails to produce a usable profile, the quality indicators provide a quick visual cue for what might have gone wrong, such as inhibition, degradation or lack of DNA in the sample. 


The PowerPlex® 18E System and other eight-colour kits are intended to be used with the Spectrum CE System and the Spectrum Compact CE System, capillary electrophoresis instruments offered by Promega that support eight-colour fragment analysis. Promega has been developing and manufacturing products for DNA-based human identification for more than 30 years.


About Promega

Promega Corporation is a leader in providing innovative solutions and technical support to the life sciences industry. The company’s portfolio of over 4,000 products support a range of life science work across areas such as cell biology; DNA, RNA and protein analysis; drug development; human identification and molecular diagnostics. For over 40 years these tools and technologies have grown in their application and are used today by scientists and technicians in labs for academic and government research, forensics, pharmaceuticals, clinical diagnostics and agricultural and environmental testing. Promega is headquartered in Madison, WI, USA with branches in 16 countries and over 50 global distributors. 


Recent news from Promega



If you have not logged into the website then please enter your details below.


Subscribe to any of our newsletters for the latest on new laboratory products, industry news, case studies and much more!

Newsletters from Lab Bulletin


Request your free copies HERE




Popular this Month

Top 10 most popular articles this month



Today's Picks



Looking for a Supplier?

Search by company or by product


Company Name:






Please note Lab Bulletin does not sell, supply any of the products featured on this website. If you have an enquiry, please use the contact form below the article or company profile and we will send your request to the supplier so that they can contact you directly.

Lab Bulletin is published by newleaf marketing communications ltd.


Media Partners


Exhibitions & Events