Special Offers & Promotions



Latest News



View Channel

New Products



View Channel

Video Presentations



View Channel

Separation Science



View Channel

Microscopy & Image Analysis



View Channel

Laboratory Automation & IT Solutions



View Channel


Cell Line Engineering Breakthrough Cuts Drug Development Times by Up To 12 Months

publication date: Nov 2, 2023
author/source: Promega UK Ltd


A new development in Cell Line Engineering technology is set to cut drug development times by up to 12 months, allowing greater reinvestment in lifesaving medicines, and a quicker path to market.

Promega, the company behind the breakthrough, has developed ready-to-use CRISPR-generated Knock-In Reporter Cell Lines that contain a proprietary, small bioluminescent tag. Not only will this discovery accelerate products to market, but it can save biotech companies up to £6 million in the drug development process.

Philip Hargreaves Ph.D, Director of Strategic Marketing & Business Development at Promega UK, comments: “The field of drug discovery is hugely competitive but is essential for the future of modern medicine. Transitioning from an early-stage platform to a ready-to-use product is a costly process with companies typically spending between £100k and £500k a month. For them, time is of the essence.

“This new development not only means that companies have more time to turn an idea into a viable solution before they run out of financial runway, but also that they have more money to reinvest in the product itself and the R&D behind it. It is a win-win.”

A contributing factor to the relatively high (approximately one-third) failure rate of biotech startups is that, at a high burn rate of their funds, they run out of money before they achieve sufficient progress to attract second round funding. 

CRISPR-generated Knock-In Reporter Cell Lines can take up to 12 months to develop, a period which could burn up to £6 million worth of cash. Using Promega’s optimised, ready-to-use products, startups can begin work with them immediately upon receipt. Consequently, the time taken to fully develop the biotech’s lead compounds or biologic entities is significantly shortened.

Hargreaves continues: “It is extremely time-consuming, and costly, for any pharma or biotech company to develop the required range of consistent, highly quality controlled, flexible knock-in cell lines with the desired reporter tag for their development needs. This breakthrough massively reduces these constraints by offering a proven, ready-to-go product that can empower them to develop lifesaving medications faster.”

In addition to accelerating the development process, Promega’s CRISPR-generated Knock-In Reporter Cell Lines free up R&D resource so that biotechs can look at a broader range of target molecules and projects, reducing and spreading their risk.   

Hargreaves concludes, “We’re giving biotechs the gift of time. By the time their first round of funding runs out, a company using our technology should be in a much better position. They’re more likely to have hit key milestones, which fosters that all-important trust amongst investors that biotech’s need to continue their research and development.”

Find out more about Promega and its CRISPR-engineered cell lines.


View Product Information



About Promega

Promega Corporation is a leader in providing innovative solutions and technical support to the life sciences industry. The company’s portfolio of over 4,000 products supports a range of life science work across areas such as cell biology; DNA, RNA and protein analysis; drug development; human identification and molecular diagnostics.

For over 40 years these tools and technologies have grown in their application and are used today by scientists and technicians in labs for academic and government research, forensics, pharmaceuticals, clinical diagnostics and agricultural and environmental testing. Promega is headquartered in Madison, WI, USA with branches in 16 countries and over 50 global distributors.


Recent news from Promega


If you have not logged into the website then please enter your details below.


Subscribe to any of our newsletters for the latest on new laboratory products, industry news, case studies and much more!

Newsletters from Lab Bulletin


Request your free copies HERE




Popular this Month

Top 10 most popular articles this month



Today's Picks



Looking for a Supplier?

Search by company or by product


Company Name:






Please note Lab Bulletin does not sell, supply any of the products featured on this website. If you have an enquiry, please use the contact form below the article or company profile and we will send your request to the supplier so that they can contact you directly.

Lab Bulletin is published by newleaf marketing communications ltd.


Media Partners


Exhibitions & Events